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Clinical and Experimental Hypertension, ISSN 1064-1963, 08/2019, Volume 41, Issue 6, pp. 577 - 582
Objective: The onset of essential hypertension is the result of a combination of genetic factors and the environment. The nuclear factor (NF)-κB1-94ins/del... 
essential hypertension | gene polymorphism | NF-κB1-94ins/del ATTG locus | Chinese Han population | Nuclear factor-κB1 | NF-kappa B1-94ins | SUSCEPTIBILITY | TUMOR | PROMOTER POLYMORPHISM | MECHANISMS | del ATTG locus | CANCER | OBESITY | Nuclear factor-kappa B1 | PHARMACOLOGY & PHARMACY | PERIPHERAL VASCULAR DISEASE | NF-KAPPA-B | TRANSCRIPTION FACTOR | ASSOCIATION | EXPRESSION
Journal Article
by Tuijnenburg, Paul and Lango Allen, Hana and Burns, Siobhan O and Burns, Siobhan and Greene, Daniel and Jansen, Machiel H and Staples, Emily and Stephens, Jonathan and Carss, Keren J and Carss, Keren and Biasci, Daniele and Baxendale, Helen and Thomas, Moira and Chandra, Anita and Kiani-Alikhan, Sorena and Longhurst, Hilary and Longhurst, Hilary J and Seneviratne, Suranjith and Seneviratne, Suranjith L and Oksenhendler, Eric and Simeoni, Ilenia and de Bree, Godelieve J and Tool, Anton T.J and van Leeuwen, Ester M.M and Ebberink, Eduard H.T.M and Meijer, Alexander B and Tuna, Salih and Whitehorn, Deborah and Brown, Matthew and Turro, Ernest and Thrasher, Adrian and Thrasher, Adrian J and Smith, Kenneth G.C and Thaventhiran, James E and Thaventhiran, James and Kuijpers, Taco W and Kuijpers, Taco and Adhya, Zoe and Alachkar, Hana and Anantharachagan, Ariharan and Antrobus, Richard and Arumugakani, Gururaj and Bacchelli, Chiara and Bethune, Claire and Bibi, Shahnaz and Boardman, Barbara and Booth, Claire and Browning, Michael and Brownlie, Mary and Clifford, Hayley and Cooper, Nichola and Davies, Sophie and Dempster, John and Devlin, Lisa and Doffinger, Rainer and Drewe, Elizabeth and Edgar, David and Egner, William and El-Shanawany, Tariq and Gaspar, Bobby and Ghurye, Rohit and Gilmour, Kimberley and Goddard, Sarah and Gordins, Pavel and Grigoriadou, Sofia and Hackett, Scott and Hague, Rosie and Harper, Lorraine and Hayman, Grant and Herwadkar, Archana and Hughes, Stephen and Huissoon, Aarnoud and Jolles, Stephen and Jones, Julie and Kelleher, Peter and Klein, Nigel and Kumararatne, Dinakantha and Laffan, James and Lear, Sara and Lorenzo, Lorena and Maimaris, Jesmeen and Manson, Ania and McDermott, Elizabeth and Millar, Hazel and Mistry, Anoop and Morrisson, Valerie and Murng, Sai and Nasir, Iman and Nejentsev, Sergey and Noorani, Sadia and Ponsford, Mark and Qasim, Waseem and Quinn, Ellen and Quinti, Isabella and Richter, Alex and Samarghitean, Crina and Sargur, Ravishankar and Savic, Sinisa and Sewall, Carrock and Shackley, Fiona and ... and NIHR BioResource-Rare Dis and NIHR BioResource–Rare Diseases Consortium
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 10/2018, Volume 142, Issue 4, pp. 1285 - 1296
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 06/2018, Volume 141, Issue 6, pp. 2085 - 2093.e1
Atopic dermatitis (AD) is a common inflammatory skin disease. A subset of patients with AD are susceptible to disseminated herpes simplex virus (HSV)... 
innate immunity | IL-29 | atopic dermatitis | nuclear factor κB1 | IFN-β1 | ankyrin repeat domain 1 | interferon regulatory 3 | Herpes simplex virus | eczema herpeticum | IFN-LAMBDA | IFN-beta 1 | PROTEIN | CYTOKINE MILIEU | DILATED CARDIOMYOPATHY | OVARIAN-CANCER | IMMUNOLOGY | ATOPIC-DERMATITIS | ALLERGY | IN-VIVO | ANKRD1 | EXPRESSION | TRANSCRIPTIONAL REPRESSOR | nuclear factor kB1 | RNA sequencing | Immune response | RNA | Dendritic cells | Herpes simplex | B cells | Biological response modifiers | T cells | Gene expression | Atopic dermatitis | Eczema | Cellular signal transduction | Interferon | Health aspects | Papillomavirus infections | Transcription factors | Immunoprecipitation | Laboratories | Pathogenesis | Genes | Viruses | Stimulation | Lymphocytes T | Infections | Dermatitis | Gene sequencing | Proteins | Signal transduction | Receptors | Demographics | Killer cells | Pathways | Lymphocytes | Skin diseases | Natural killer cells | Cytokines | siRNA | Eczema herpeticum | Pattern recognition | Ribonucleic acid--RNA | Patients | Studies | Polymerase chain reaction | Human subjects | Interferon regulatory factor 7 | Signaling | Monocytes | Acids | Lymphocytes B | Interferon regulatory factor 3 | Production methods | Antigen-presenting cells | Herpes viruses | Ankyrin | Interferon regulatory factor | Viral infections
Journal Article
Journal of Neural Transmission, ISSN 0300-9564, 9/2002, Volume 109, Issue 9, pp. 1181 - 1188
Biochemical and morphological studies revealed that oxidative stress and apoptosis play a role in neurodegeneration in Parkinson's disease (PD). Reactive... 
neurodegeneration | Parkinson's disease | genetics | nuclear factor Kappa B | Genetics | Nuclear factor Kappa B | Neurodegeneration | APOPTOSIS | SUSCEPTIBILITY | ALPHA-SYNUCLEIN | LOCUS | NEUROSCIENCES | CLINICAL NEUROLOGY | TUMOR-NECROSIS-FACTOR | MAPS | NEURONS | NF-KAPPA-B | TRANSCRIPTION FACTOR | SUBUNIT
Journal Article
Biomedical reports, ISSN 2049-9434, 09/2015, Volume 3, Issue 5, p. 736
Coronary artery disease (CAD) is the leading cause of fatalities worldwide. Nuclear factor (NF)-κB is a transcription factor that controls cell proliferation,... 
Journal Article
Biochemical Journal, ISSN 0264-6021, 06/2013, Volume 452, Issue 2, pp. 359 - 365
Activation of PKR (double-stranded-RNA-dependent protein kinase) by DNA plasmids decreases translation, and limits the amount of recombinant protein produced... 
Double-stranded-RNA- dependent protein kinase (PKR) | Virus protein 35 (VP35) | Tumour progression locus 2 (TPL-2) | A20-binding inhibitor of nuclear factor κB 2 (ABIN-2) | Cancer Osaka thyroid (COT) | Nuclear factor κB 1 (NF-κB1) | double-stranded-RNA-dependent protein kinase (PKR) | tumour progression locus 2 (TPL-2) | KAPPA-B-KINASE | virus protein 35 (VP35) | PROTEIN-KINASE | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIPOPOLYSACCHARIDE ACTIVATION | MECHANISMS | PROTEOLYSIS | cancer Osaka thyroid (COT) | DIRECT PHOSPHORYLATION | TPL-2 | TRANSIENT GENE-EXPRESSION | A20-binding inhibitor of nuclear factor kappa B 2 (ABIN-2) | nuclear factor kappa B 1 (NF-kappa B1) | SIGNAL-REGULATED KINASE | MAP Kinase Kinase Kinases - genetics | Humans | Viral Regulatory and Accessory Proteins - genetics | NF-kappa B p50 Subunit - biosynthesis | Multiprotein Complexes - genetics | Proto-Oncogene Proteins - genetics | Up-Regulation - genetics | Recombinant Proteins - genetics | NF-kappa B p50 Subunit - genetics | Recombinant Proteins - biosynthesis | Ebolavirus - genetics | Proto-Oncogene Proteins - biosynthesis | Transfection | MAP Kinase Kinase Kinases - biosynthesis | Multiprotein Complexes - biosynthesis | Adaptor Proteins, Signal Transducing - genetics | HEK293 Cells | Viral Regulatory and Accessory Proteins - physiology | Adaptor Proteins, Signal Transducing - biosynthesis | Ebolavirus - physiology | IKK, IκB kinase | TNF, tumour necrosis factor | VP35, virus protein 35 | HEK, human embryonic kidney | nuclear factor κB 1 (NF-κB1) | DTT, dithiothreitol | ERK, extracellular-signal-regulated kinase | GST, glutathione transferase | IκB, inhibitor of NF-κB | TPL-2, tumour progression locus 2 | BMDM, bone-marrow-derived macrophage | PKR, double-stranded RNA-dependent protein kinase | TBK1, TANK [TRAF (tumour-necrosis-factor-receptor-associated factor)-associated NF-κB activator]-binding kinase 1 | NF-κB, nuclear factor κB | DM, decyl β-D-maltopyranoside | MKK, MAPK kinase | Accelerated Publication | HA, haemagglutinin | TCEP, tris-(2-carboxyethyl)phosphine | Hsp, heat-shock protein | MBP, myelin basic protein | ABIN-2, A20-binding inhibitor of nuclear factor κB 2 | MAPK, mitogen-activated protein kinase
Journal Article
Biochemical Journal, ISSN 0264-6021, 08/2005, Volume 390, Issue 1, pp. 317 - 324
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2004, Volume 382, Issue 2, pp. 393 - 409
Two members of the NF-kappaB (nuclear factor kappaB)/Rel transcription factor family, NF-kappaB1 and NF-kappaB2, are produced as precursor proteins, NF-kappaB1... 
IκB kinase (IKK) | p100 | Tumour progression locus-2 (TPL-2) | Nuclear factor κB (NF-κB) | p105 | Toll-like receptor (TLR) | nuclear factor kappa B (NF-kappa B) | TRCP UBIQUITIN LIGASE | I kappa B kinase (IKK) | BIOCHEMISTRY & MOLECULAR BIOLOGY | P105 REQUIRES PHOSPHORYLATION | ALLERGIC AIRWAY INFLAMMATION | KINASE KINASE KINASE | P50 SUBUNIT | GLYCINE-RICH REGION | TUMOR-NECROSIS-FACTOR | TOLL-LIKE RECEPTORS | tumour progression locus-2 (TPL-2) | NF-KAPPA-B | SIGNAL-TRANSDUCTION PATHWAY | TNF, tumour necrosis factor | GC, germinal centre | NEMO, nuclear factor κB essential modulator | MAP 3-kinase, MAP kinase kinase kinase | BAFF, B-cell activating factor | ERK, extracellular-signal-regulated kinase | Fn14, fibroblast-growth-factor-inducible 14 | ABIN, A20-binding inhibitor of nuclear factor κB | GM-CSF, granulocyte–macrophage colony-stimulating factor | GSK, glycogen synthase kinase | Dif, Dorsal-related immunity factor | EBNA1, EBV nuclear antigen 1 | BMDM, bone-marrow-derived macrophage | NF-κB, nuclear factor κB | SCF, Skp1 | Imd, immune deficiency | F-box | IL, interleukin | MAP kinase, mitogen-activated protein kinase | EBV, Epstein–Barr virus | LPS, lipopolysaccharide | IFNβ, interferon-β | IκB, inhibitor of nuclear factor κB | TRAF, TNF-receptor-associated factor | TLR, Toll-like receptor | DC, dendritic cell | IKK, IκB kinase | GRR, glycine-rich region | Review | JNK, c-Jun N-terminal kinase | PGRP-LC, peptidoglycan recognition protein LC | ERK kinase | RANKL, receptor activator of NF-κB ligand | LTβR, lymphotoxin-β receptor | MIP, macrophage inflammatory protein | DD, death domain | HTLV-1, human T-cell leukaemia virus type 1 | MEK, MAP kinase | COX-2, cyclo-oxygenase-2 | TH2, T-helper 2 | TH1, T-helper 1 | LMP1, latent membrane protein 1 | TPL-2, tumour progression locus-2 | TWEAK, TNF-like weak inducer of apoptosis | Cul1 | PEST region, polypeptide sequence enriched in proline (P), glutamic acid (E), serine (S) and threonine (T) | RHD, Rel homology domain | nuclear factor κB (NF-κB) | NIK, NF-κB-inducing kinase | MEF, mouse embryo fibroblast | βTrCP, β-transducin repeat-containing protein
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 11/2013, Volume 24, Issue 22, pp. 3577 - 3583
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 03/2001, Volume 16, Issue 3, pp. 501 - 510
Previously, we showed that exposure of human osteoblasts to titanium particles stimulates protein tyrosine phosphorylation (PTP), activates the transcription... 
procollagen | particle | promoter | nuclear factor κB | osteoblast | Particle | Promoter | Osteoblast | Procollagen | Nuclear factor κB
Journal Article