Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (184440) 184440
Book Review (24758) 24758
Publication (20823) 20823
Conference Proceeding (4884) 4884
Newspaper Article (1944) 1944
Book Chapter (1933) 1933
Newsletter (1878) 1878
Book / eBook (736) 736
Dissertation (582) 582
Patent (307) 307
Report (213) 213
Government Document (158) 158
Magazine Article (104) 104
Trade Publication Article (62) 62
Web Resource (55) 55
Reference (25) 25
Data Set (18) 18
Paper (13) 13
Transcript (8) 8
Streaming Video (5) 5
Journal / eJournal (4) 4
Presentation (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (142815) 142815
humans (90834) 90834
animals (74287) 74287
male (35682) 35682
mice (35412) 35412
female (34873) 34873
biochemistry & molecular biology (34093) 34093
radiology, nuclear medicine & medical imaging (31356) 31356
cell biology (25360) 25360
proteins (21295) 21295
oncology (21116) 21116
expression (20036) 20036
cancer (17717) 17717
research (16931) 16931
gene expression (16424) 16424
rats (16292) 16292
analysis (15057) 15057
nuclear proteins - metabolism (14991) 14991
middle aged (14771) 14771
adult (14655) 14655
molecular sequence data (13849) 13849
article (13388) 13388
signal transduction (13350) 13350
nuclear magnetic resonance--nmr (13076) 13076
gene-expression (12539) 12539
nuclear proteins - genetics (12477) 12477
apoptosis (12044) 12044
transcription factors - metabolism (11814) 11814
cell line (11655) 11655
protein binding (11468) 11468
activation (11391) 11391
neurosciences (11127) 11127
cells (10837) 10837
amino acid sequence (10749) 10749
receptors, cytoplasmic and nuclear - metabolism (10738) 10738
aged (10639) 10639
cell line, tumor (10635) 10635
cells, cultured (10392) 10392
physiological aspects (10113) 10113
multidisciplinary sciences (10004) 10004
transcription factors - genetics (9689) 9689
mutation (9681) 9681
research article (9463) 9463
ligands (9290) 9290
phosphorylation (9277) 9277
genetic aspects (9155) 9155
medicine (9128) 9128
medicine & public health (9068) 9068
tumors (9016) 9016
biology (8976) 8976
genes (8725) 8725
pharmacology & pharmacy (8503) 8503
dna-binding proteins - metabolism (8499) 8499
endocrinology & metabolism (8417) 8417
binding (8398) 8398
biophysics (8289) 8289
base sequence (8233) 8233
in-vivo (8165) 8165
protein (8157) 8157
binding sites (8066) 8066
chemistry, inorganic & nuclear (8041) 8041
nuclear receptors (7984) 7984
transcription factors (7846) 7846
brain (7741) 7741
nuclear medicine (7715) 7715
gene expression regulation (7570) 7570
rodents (7525) 7525
cell nucleus - metabolism (7439) 7439
transcription (7410) 7410
immunohistochemistry (7393) 7393
inflammation (7390) 7390
magnetic resonance imaging (7300) 7300
receptors (7297) 7297
health aspects (7244) 7244
mice, inbred c57bl (7182) 7182
immunology (7176) 7176
genetics & heredity (7051) 7051
gene (6912) 6912
dna-binding proteins - genetics (6902) 6902
rna, messenger - metabolism (6886) 6886
receptor (6851) 6851
breast cancer (6793) 6793
receptors, cytoplasmic and nuclear - genetics (6785) 6785
transfection (6762) 6762
metabolism (6681) 6681
care and treatment (6544) 6544
studies (6464) 6464
nuclear receptor (6415) 6415
abridged index medicus (6342) 6342
in-vitro (6241) 6241
identification (6141) 6141
science (6102) 6102
transcription, genetic (6038) 6038
differentiation (5908) 5908
imaging / radiology (5888) 5888
models, molecular (5766) 5766
medicine, research & experimental (5712) 5712
biochemistry (5554) 5554
liver (5478) 5478
kinases (5438) 5438
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (345) 345
Online Resources - Online (61) 61
UTL at Downsview - May be requested (45) 45
Engineering & Comp. Sci. - Stacks (39) 39
UofT at Mississauga - Stacks (36) 36
Collection Dvlpm't (Acquisitions) - Closed Orders (35) 35
Collection Dvlpm't (Acquisitions) - Vendor file (33) 33
Robarts - Stacks (33) 33
UofT at Scarborough - Stacks (29) 29
Chemistry (A D Allen) - Stacks (14) 14
Physics - Stacks (11) 11
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (11) 11
St. Michael's College (John M. Kelly) - 2nd Floor (9) 9
Trinity College (John W Graham) - Stacks (9) 9
Gerstein Science - Circulation Desk (4) 4
Astronomy & Astrophysics - Ask at library (3) 3
Earth Sciences (Noranda) - Stacks (3) 3
Law (Bora Laskin) - Stacks (3) 3
Aerospace - Stacks (2) 2
Baycrest Hospital - Stacks (2) 2
Gerstein Science - Missing (2) 2
Gerstein Science - Reference (2) 2
Physics - Missing (2) 2
Physics - Reference (2) 2
Robarts - Storage (2) 2
Scarborough Hospital - Online (2) 2
St. Michael's Hospital - Stacks (2) 2
Engineering & Comp. Sci. - Reference (1) 1
Gerstein Science - Bindery (1) 1
Gerstein Science - Not Returned (1) 1
Gerstein Science - Periodical Stacks (1) 1
Lakeridge Health Sciences - Oshawa (1) 1
Mathematical Sciences - Stacks (1) 1
New College (Ivey) - Stacks (1) 1
Physics - Storage (1) 1
Regis College - Stacks (1) 1
Royal Ontario Museum - Stacks (1) 1
St. Michael's College (John M. Kelly) - 3rd Floor (1) 1
Thomas Fisher Rare Book - Rare Book (1) 1
Toronto East General Hospital - Stacks (1) 1
University College (Laidlaw) - May be requested in 6-10 wks (1) 1
University College (Laidlaw) - Stacks (1) 1
Victoria University E.J. Pratt - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (191902) 191902
Japanese (662) 662
Chinese (626) 626
French (445) 445
German (304) 304
Spanish (162) 162
Russian (139) 139
Polish (78) 78
Portuguese (73) 73
Korean (59) 59
Turkish (25) 25
Czech (22) 22
Italian (22) 22
Hungarian (15) 15
Dutch (12) 12
Ukrainian (9) 9
Danish (6) 6
Arabic (5) 5
Greek (5) 5
Swedish (5) 5
Catalan (3) 3
Croatian (3) 3
Finnish (3) 3
Norwegian (3) 3
Slovenian (3) 3
Romanian (2) 2
Serbian (2) 2
Esperanto (1) 1
Indonesian (1) 1
Latvian (1) 1
Slovak (1) 1
Welsh (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Receptor
Receptor, ISSN 1052-8040, 1990
Periodicals | Cell receptors | Ligand binding (Biochemistry) | Carrier proteins
Journal
Details down arrow
2. Full Text Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors
by Ruili Huang and Menghang Xia and Ming-Hsuang Cho and Srilatha Sakamuru and Paul Shinn and Keith A. Houck and David J. Dix and Richard S. Judson and Kristine L. Witt and Robert J. Kaylock and Raymond R. Tice and Christopher P. Austin
Environmental Health Perspectives, ISSN 0091-6765, 8/2011, Volume 119, Issue 8, pp. 1142 - 1148
Background: The large and increasing number of chemicals released into the environment demands more efficient and cost-effective approaches for assessing... 
Chemical hazards | Receptors | Genomics | Environmental health | Agonists | Ligands | Cytotoxicity | Libraries | Environmental agencies | Research | Nuclear receptors | Chemical genomics | qHTS | Assay performance | Tox21 | assay performance | TOXICITY | ANTAGONISM | IDENTIFICATION | ESTROGEN-RECEPTOR | nuclear receptors | ENVIRONMENTAL SCIENCES | IN-VITRO | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | EVOLUTION | DISEASE | ASSAYS | SUPERFAMILY | HEALTH | chemical genomics | cytotoxicity | Peroxisome Proliferator-Activated Receptors - agonists | Cell Line | Retinoid X Receptor alpha - metabolism | Peroxisome Proliferator-Activated Receptors - antagonists & inhibitors | Humans | Orphan Nuclear Receptors - agonists | Receptors, Androgen - metabolism | Receptors, Cytoplasmic and Nuclear - agonists | Orphan Nuclear Receptors - metabolism | PPAR gamma - metabolism | Receptors, Thrombin - antagonists & inhibitors | Retinoid X Receptor alpha - agonists | Fragile X Mental Retardation Protein | Orphan Nuclear Receptors - antagonists & inhibitors | Retinoid X Receptor alpha - antagonists & inhibitors | PPAR gamma - antagonists & inhibitors | Receptors, Thrombin - agonists | Liver X Receptors | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Peroxisome Proliferator-Activated Receptors - metabolism | Receptors, Thrombin - metabolism | Estrogen Receptor alpha - metabolism | Environmental Pollutants - toxicity | Receptors, Cytoplasmic and Nuclear - metabolism | Environmental aspects | Physiological aspects | Cell receptors | Health aspects | Chemicals | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Nuclear receptors
: a practical approach
by Picard, Didier
1999, Practical approach series, ISBN 9780199637430, Volume 207, xviii, 285
Receptors, Steroid | Receptors | Transcription Factors | Receptors, Cytoplasmic and Nuclear | Steroid hormones | Nuclear receptors (Biochemistry)
Book
Details down arrow
4. Full Text Oestrogen receptor-related receptor alpha (ERRα) and oestrogen receptors (ERα and ERβ) exhibit different gene expression in human colorectal tumour progression
by Cavallini, Aldo and Notarnicola, Maria and Giannini, Romina and Montemurro, Severino and Lorusso, Dionigi and Visconti, Angelo and Minervini, Fiorenza and Caruso, Maria Gabriella
European Journal of Cancer, ISSN 0959-8049, 2005, Volume 41, Issue 10, pp. 1487 - 1494
We have investigated the presence of oestrogen receptor-related (ERR) mRNA in human colorectal tumour tissues and adjacent normal mucosa by reverse... 
Tumour progression | Peroxisome proliferator-activated receptor γ coactivator-1 | Oestrogen receptor beta | Peroxisome proliferator-activated receptor γ | Oestrogen receptor-related receptor | Colorectal carcinoma | Oestrogen receptor alpha | GAMMA | CELLS | tumour progression | peroxisome proliferator-activated receptor gamma coactivator-1 | oestrogen receptor beta | SUBTYPES | TRANSCRIPTION | oestrogen receptor alpha | oestrogen receptor-related receptor | colorectal carcinoma | COLON-CANCER | BREAST-CANCER | MUCOSA | ONCOLOGY | COACTIVATOR PGC-1 | MICE | peroxisome proliferator-activated receptor gamma | BINDING | Gene Expression | Receptors, Estrogen - metabolism | Receptors, Estrogen - genetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Receptors, Cytoplasmic and Nuclear - genetics | PPAR gamma - metabolism | RNA, Messenger - metabolism | Disease Progression | Estrogen Receptor beta - metabolism | Transcription Factors - metabolism | Estrogen Receptor alpha - genetics | Estrogen Receptor beta - genetics | Reverse Transcriptase Polymerase Chain Reaction - methods | Aged, 80 and over | Estrogen Receptor alpha - metabolism | Female | Aged | Colorectal Neoplasms - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Messenger RNA | Reverse transcriptase | Analysis | Gastrointestinal diseases | Estrogen | Colorectal cancer | Development and progression | Gene expression | Tumors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. The AH receptor in biology and toxicology
by Pohjanvirta, R
2012, 1. Aufl., ISBN 0470601825, xiii, 533
This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage... 
toxicology | toxicity | risk assessment | environmental pollutants | transcription factors | signal transduction | receptors, aryl hydrocarbon | polycyclic aromatic hydrocarbons | pollution | dioxins | agonists | nuclear receptors(biochemistry) | metabolism | Science | Chemistry | Industrial & Technical | Dioxins | Toxicology | Transcription factors | Polycyclic aromatic hydrocarbons | Metabolism | Nuclear receptors (Biochemistry)
Book
Details down arrow
6. Full Text Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity
by Gong, Hua and Weinstein, David S and Lu, Zhonghui and Duan, James J.-W and Stachura, Sylwia and Haque, Lauren and Karmakar, Ananta and Hemagiri, Hemalatha and Raut, Dhanya Kumar and Gupta, Arun Kumar and Khan, Javed and Camac, Dan and Sack, John S and Pudzianowski, Andrew and Wu, Dauh-Rurng and Yarde, Melissa and Shen, Ding-Ren and Borowski, Virna and Xie, Jenny H and Sun, Huadong and D'Arienzo, Celia and Dabros, Marta and Galella, Michael A and Wang, Faye and Weigelt, Carolyn A and Zhao, Qihong and Foster, William and Somerville, John E and Salter-Cid, Luisa M and Barrish, Joel C and Carter, Percy H and Dhar, T.G. Murali
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 01/2018, Volume 28, Issue 2, pp. 85 - 93
We disclose the optimization of a high throughput screening hit to yield benzothiazine and tetrahydroquinoline sulfonamides as potent RORγt inverse agonists.... 
POTENT | AUTOIMMUNE | CHEMISTRY, MEDICINAL | INHIBITION | INTERLEUKIN-17 | NUCLEAR RECEPTORS | MODULATORS | DISEASE | GENE-EXPRESSION | CHEMISTRY, ORGANIC | DISCOVERY | PSORIASIS | Rheumatoid factor | Multiple sclerosis | Sulfonamides | Analysis | Gastrointestinal diseases | Liver | Arthritis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Nuclear receptors
by Russell, David W and Mangelsdorf, David J
2003, Methods in enzymology, ISBN 9780121822675, Volume 364., xliv, 536 p., [20] p. of plates
Nuclear Receptors are inducible transcription factors that mediate complex effects on development, differentiation and homeostasis. They regulate the... 
Complexes récepteur-ligand | Receptor-ligand complexes | Nuclear receptors (Biochemistry) | Récepteurs nucléaires (Biochimie) | Hormone receptors | Handbooks, manuals, etc
Book
Details down arrow
8. Full Text Nuclear Hormone Receptor Activity of Polybrominated Diphenyl Ethers and Their Hydroxylated and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells
by Hiroyuki Kojima and Shinji Takeuchi and Naoto Uramaru and Kazumi Sugihara and Takahiko Yoshida and Shigeyuki Kitamura
Environmental Health Perspectives, ISSN 0091-6765, 8/2009, Volume 117, Issue 8, pp. 1210 - 1218
Background: An increasing number of studies are reporting the existence of polybrominated diphenyl ethers (PBDEs) and their hydroxylated (HO) and methoxylated... 
Hormone receptors | Hormone metabolism | Receptors | Dose response relationship | Cellular metabolism | Halogenated diphenyl ethers | Plasmids | Congeners | Flame retardants | Research | Ethers | Estrogen receptor | Androgen receptor | Glucocorticoid receptor | Reporter gene assay | Brominated diphenyl ether | Thyroid hormone receptor | Chinese hamster ovary cells | glucocorticoid receptor | ESTROGEN-RECEPTORS | estrogen receptor | THYROID-HORMONE | ALPHA | brominated diphenyl ether | reporter gene assay | BETA | ENVIRONMENTAL SCIENCES | IN-VITRO | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | androgen receptor | thyroid hormone receptor | BROMINATED FLAME RETARDANTS | REPORTER GENE ASSAYS | 200 PESTICIDES | TOXICOLOGY | EXPOSURE | Androgen Receptor Antagonists | Cricetinae | Receptors, Glucocorticoid - antagonists & inhibitors | Cricetulus | Humans | Thyroid Hormone Receptors beta - antagonists & inhibitors | Estrogen Receptor alpha - antagonists & inhibitors | Thyroid Hormone Receptors alpha - antagonists & inhibitors | Receptors, Cytoplasmic and Nuclear - agonists | Halogenated Diphenyl Ethers - chemistry | Receptors, Glucocorticoid - agonists | Halogenated Diphenyl Ethers - metabolism | Androgens | Animals | Estrogen Receptor alpha - agonists | Estrogen Receptor beta - agonists | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Thyroid Hormone Receptors beta - agonists | Molecular Structure | Thyroid Hormone Receptors alpha - agonists | Estrogen Receptor beta - antagonists & inhibitors | CHO Cells | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological aspects | Metabolites | Health aspects | Polybrominated biphenyls | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Principles of molecular regulation
by Conn, P. Michael and Means, Anthony R
2000, ISBN 0896036308, xiv, 474
Molecular endocrinology | Cellular signal transduction | Nuclear receptors (Biochemistry)
Book
Details down arrow
10. Full Text Abnormal CD161+ immune cells and retinoic acid receptor–related orphan receptor γt–mediate enhanced IL-17F expression in the setting of genetic hypertension
by Singh, Madhu V and Cicha, Michael Z and Kumar, Santosh and Meyerholz, David K and Irani, Kaikobad and Chapleau, Mark W and Abboud, François M
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 09/2017, Volume 140, Issue 3, pp. 809 - 821.e3
Hypertension is considered an immunologic disorder. However, the role of the IL-17 family in genetic hypertension in the spontaneously hypertensive rat (SHR)... 
Hypertension | CD161 | IL-17 | spontaneously hypertensive rat | digoxin | T cells | retinoic acid receptor–related orphan receptor γt | TH17 | Toll-like receptor | gene expression | innate immune system | T | 17 | INTERLEUKIN 17 | ACTIVATION | ENDOTHELIAL DYSFUNCTION | ORGAN DAMAGE | IMMUNOLOGY | NICOTINIC ACETYLCHOLINE-RECEPTORS | RESPONSES | ALLERGY | INFLAMMATION | T(H)17 | retinoic acid receptor-related orphan receptor gamma t | DIFFERENTIATION | TH17 CELLS | LYMPHOCYTES | Animals, Newborn | Rats, Inbred SHR | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - antagonists & inhibitors | Poly I-C - pharmacology | Cells, Cultured | Interleukin-17 - immunology | Interleukin-17 - physiology | Interleukin-17 - genetics | Rats, Inbred WKY | Male | Hypertension - immunology | Spleen - cytology | Toll-Like Receptor 3 - agonists | NK Cell Lectin-Like Receptor Subfamily B - immunology | Digoxin - pharmacology | Hypertension - physiopathology | Vasodilation | Aging - immunology | Animals | Aorta, Thoracic - physiology | Blood Pressure - drug effects | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | RNA - metabolism | Flow cytometry | Transcription factors | Digoxin | Disease | Helper cells | Nervous system | Lymphocytes T | Birth | Kinases | Signal transduction | Splenocytes | Lymphocytes | Rodents | Measurement methods | Blood pressure | Immune system | Spleen | Immune response | Cytokines | Rats | Pharmacology | Inflammation | T cell receptors | Interleukin 17 | Endothelium | Immune systems | Acids | Prostate | Surface markers | Retinoic acid | Nicotine | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Regulated Expression of Nuclear Receptor RORγt Confers Distinct Functional Fates to NK Cell Receptor-Expressing RORγt + Innate Lymphocytes
by Vonarbourg, Cedric and Mortha, Arthur and Bui, Viet L and Hernandez, Pedro P and Kiss, Elina A and Hoyler, Thomas and Flach, Melanie and Bengsch, Bertram and Thimme, Robert and Hölscher, Christoph and Hönig, Manfred and Pannicke, Ulrich and Schwarz, Klaus and Ware, Carl F and Finke, Daniela and Diefenbach, Andreas
Immunity, ISSN 1074-7613, 2010, Volume 33, Issue 5, pp. 736 - 751
Whether the recently identified innate lymphocyte population coexpressing natural killer cell receptors (NKRs) and the nuclear receptor RORγt is part of the NK... 
LYMPHOID-ORGAN DEVELOPMENT | INTESTINAL INFLAMMATION | TISSUE-INDUCER CELLS | SEVERE COMBINED IMMUNODEFICIENCY | NATURAL-KILLER | COMMENSAL MICROFLORA | INFLAMMATORY-BOWEL-DISEASE | TYPE-2 IMMUNITY | NKP46(+) CELLS | IMMUNOLOGY | NODE DEVELOPMENT | Up-Regulation | Inflammatory Bowel Diseases - immunology | Interferon-gamma - metabolism | Interleukin-15 - immunology | Interleukins - metabolism | Intestines - immunology | Lymphoid Tissue - immunology | Interleukin-7 - genetics | T-Lymphocytes, Helper-Inducer - immunology | Interleukins - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Killer Cells, Natural - immunology | Interleukin-7 - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | Lymphocyte Activation | Down-Regulation | Mice, Inbred C57BL | Interleukin-12 - metabolism | Animals | Interleukin-7 - immunology | Intestines - microbiology | Interferon-gamma - immunology | Interleukin-15 - metabolism | Interleukin-12 - immunology | Mice | Cell Lineage - immunology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Transcriptional targets shared by estrogen receptor-related receptors (ERRs) and estrogen receptor (ER) α, but not by ERβ
by Gustafsson, Jan-Ã…ke and Vanacker, Jean-Marc and Pettersson, Katarina and Laudet, Vincent
The EMBO Journal, ISSN 0261-4189, 08/1999, Volume 18, Issue 15, pp. 4270 - 4279
The physiological activities of estrogens are thought to be mediated by specific nuclear receptors, ERα and ERβ. However, certain tissues, such as the bone,... 
nuclear receptors | estrogen | orphan receptors | transcriptional interference | Nuclear receptors | Transcriptional interference | Orphan receptors | Estrogen | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ORPHAN RECEPTOR | IDENTIFICATION | HETERODIMERS | CELL BIOLOGY | OSTEOPONTIN | SEQUENCE | PROMOTER | EXPRESSION | BINDING
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Structure–activity relationship-guided development of retinoic acid receptor-related orphan receptor gamma (RORγ)-selective inverse agonists with a phenanthridin-6(5H)-one skeleton from a liver X receptor ligand
by Nishiyama, Yuko and Nakamura, Masahiko and Misawa, Takashi and Nakagomi, Madoka and Makishima, Makoto and Ishikawa, Minoru and Hashimoto, Yuichi
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 05/2014, Volume 22, Issue 9, pp. 2799 - 2808
Retinoic acid receptor-related orphan receptors (RORs), which belong to the nuclear receptor superfamily, regulate many physiological processes, including... 
ROR | Phenanthridinone | Inverse agonist | LXR | DESIGN | CHEMISTRY, MEDICINAL | ANALOGS | MODULATORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | ALPHA | DISCOVERY | DIPHENYLPENTANE SKELETON | MULTI-TEMPLATE | ROR-GAMMA | CELL-DIFFERENTIATION | DERIVATIVES | Protein Structure, Tertiary | Humans | Receptors, Retinoic Acid - metabolism | Orphan Nuclear Receptors - metabolism | Receptors, Retinoic Acid - chemistry | Phenanthrenes - chemistry | Phenanthrenes - chemical synthesis | Protein Isoforms - metabolism | Orphan Nuclear Receptors - chemistry | Protein Isoforms - chemistry | Drug Inverse Agonism | Liver X Receptors | HEK293 Cells | Protein Binding | Ligands | Phenanthrenes - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Topical Vitamin D3 and Low-Calcemic Analogs Induce Thymic Stromal Lymphopoietin in Mouse Keratinocytes and Trigger an Atopic Dermatitis
by Mei Li and Pierre Hener and Zhikun Zhang and Shigeaki Kato and Daniel Metzger and Pierre Chambon
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2006, Volume 103, Issue 31, pp. 11736 - 11741
We have demonstrated that cytokine thymic stromal lymphopoietin (TSLP), whose expression is rapidly induced upon keratinocyteselective ablation of retinoid X... 
T lymphocytes | Receptors | Ethanol | Vitamin D | Cytokines | Cholecalciferols | Keratinocytes | Skin | Mast cells | Inflammation | Retinoic acid receptor | Retinoid X receptor | Retinoic acid | Vitamin D receptor | retinoid X receptor | ALLERGIC INFLAMMATION | CELLS | MULTIDISCIPLINARY SCIENCES | skin | NUCLEAR RECEPTOR SUPERFAMILY | retinoic acid receptor | retinoic acid | GENE | ASTHMA | ABLATION | vitamin D receptor | 1,25-DIHYDROXYVITAMIN D-3 | MICE | ASSOCIATION | Skin - cytology | Retinoid X Receptor alpha - metabolism | Calcium - metabolism | Dermatologic Agents - administration & dosage | Humans | Calcitriol - adverse effects | Dermatologic Agents - adverse effects | Receptors, Calcitriol - genetics | Receptors, Retinoic Acid - genetics | Calcitriol - administration & dosage | Calcitriol - analogs & derivatives | Dermatitis, Atopic - chemically induced | Vitamins - immunology | Receptors, Retinoic Acid - agonists | Dermatitis, Atopic - immunology | Female | Cytokines - genetics | Dimerization | Skin - pathology | Cytokines - immunology | Retinoid X Receptor beta - metabolism | Vitamins - chemistry | Cells, Cultured | Retinoid X Receptor beta - genetics | Mice, Transgenic | Receptors, Retinoic Acid - metabolism | Keratinocytes - cytology | Receptors, Calcitriol - metabolism | Keratinocytes - immunology | Mice, Knockout | Retinoid X Receptor alpha - agonists | Vitamins - adverse effects | Animals | Retinoid X Receptor alpha - genetics | Mice | Dermatologic Agents - immunology | Administration, Topical | Retinoids - immunology | Skin - drug effects | Vitamins - administration & dosage | Calcitriol - immunology | Retinoid X Receptor beta - agonists | Physiological aspects | Causes of | Vitamin D3 | Atopic dermatitis | Tretinoin | Lymphocyte receptors | Genotype & phenotype | Molecular biology | Dermatitis | Index Medicus | Dermatitis, Atopic | Calcium | Calcitriol | Retinoid X Receptor alpha | Retinoids | Life Sciences | Retinoid X Receptor beta | Receptors, Retinoic Acid | Biochemistry, Molecular Biology | Vitamins | Dermatologic Agents | Receptors, Calcitriol | Biological Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights