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Nucleic Acids Research, ISSN 0305-1048, 01/2018, Volume 46, Issue D1, pp. D762 - D769
Abstract The UCSC Genome Browser (https://genome.ucsc.edu) provides a web interface for exploring annotated genome assemblies. The assemblies and annotation... 
NETWORK | OFF-TARGET | INTEGRATION | ANNOTATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPREHENSIVE RESOURCE | KEGG | CORUM | PROTEINS | CURATION | BASE | Database Issue
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 12/2019, p. 115300
The imidazobenzoxazin-5-thione MV1035, synthesized as a new sodium channel blocker, has been tested on tumoral cells that differ for origin and for expressed... 
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 07/2018, Volume 46, Issue W1, pp. W242 - W245
Abstract CRISPOR.org is a web tool for genome editing experiments with the CRISPR-Cas9 system. It finds guide RNAs in an input sequence and ranks them... 
CRISPR-CAS9 | DESIGN | OFF-TARGET | BIOCHEMISTRY & MOLECULAR BIOLOGY | TOOL | Web Server Issue
Journal Article
BioTechniques, ISSN 0736-6205, 11/2018, Volume 65, Issue 5, pp. 259 - 267
GUIDE-seq was developed to detect CRISPR/Cas9 off-target. However, as originally reported, it was associated with a high level of nonspecific amplification. In... 
TEG-seq | CRISPR/cas9 | off-target | gene editing | GUIDE-seq
Journal Article
Nature, ISSN 0028-0836, 04/2015, Volume 520, Issue 7546, pp. 186 - 191
Journal Article
Nature Reviews Genetics, ISSN 1471-0056, 02/2018, Volume 19, Issue 2, pp. 67 - 80
Exciting new technologies are often self-limiting in their rollout, as access to state-of-the-art instrumentation or the need for years of hands-on experience,... 
DRUG | OFF-TARGET | DNA | GENETICS & HEREDITY | RNAI SCREENS | LARGE-SCALE | SGRNA DESIGN | CAS9 | IDENTIFICATION | GENOME | REVEALS | Genes | Genomics | Genetic screening | CRISPR | New technology
Journal Article
BMB Reports, ISSN 1976-6696, 2017, Volume 50, Issue 5, p. 247
CRISPR/Cas9 is the latest tool introduced in the field of genome engineering and is so far the best genome-editing tool as compared to its precedents such as,... 
Off-target | CRISPR/Cas9 | Autophagy | PAM | gRNA
Journal Article
Nature Reviews Genetics, ISSN 1471-0056, 05/2016, Volume 17, Issue 5, pp. 300 - 312
Journal Article
The FEBS Journal, ISSN 1742-464X, 12/2019, Volume 286, Issue 23, pp. 4675 - 4692
The ability to alter single bases without homology directed repair (HDR) of double‐strand breaks provides a potential solution for editing livestock genomes... 
nonsense mutation | genome editing | large animal | base editing | point mutation | off‐target mutation
Journal Article
Vaccine, ISSN 0264-410X, 01/2020, Volume 38, Issue 4, pp. 859 - 867
Clinical and historical data underscore the ability of influenza viruses to ally with Staphylococcus aureus and predispose the host for secondary bacterial... 
Journal Article
Cell Stem Cell, ISSN 1934-5909, 05/2016, Volume 18, Issue 5, pp. 573 - 586
Journal Article