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Neurology, ISSN 0028-3878, 04/2019, Volume 92, Issue 16, pp. e1890 - e1898
OBJECTIVETo identify promising blood-based biomarkers and novel etiologic pathways of disease risk, we applied an untargeted serum metabolomics profiling in a... 
BIOMARKERS | VARIANTS | PATHWAY | CYP4A11 | OMEGA-OXIDATION | IDENTIFICATION | HEALTH-CARE PROFESSIONALS | ASSOCIATION | ATHEROSCLEROSIS RISK | CLINICAL NEUROLOGY
Journal Article
MOLECULAR PHARMACOLOGY, ISSN 0026-895X, 06/2009, Volume 75, Issue 6, pp. 1337 - 1346
Genetic polymorphisms in VKORC1 and CYP2C9, genes controlling vitamin K-1 (VK1) epoxide reduction and (S)-warfarin metabolism, respectively, are major... 
HYDROXYLASE | METABOLISM | CHAIN FATTY-ACIDS | PHARMACOGENOMICS | HEPG2 CELLS | OMEGA-OXIDATION | PHARMACOLOGY & PHARMACY | HUMAN LIVER-MICROSOMES | GAMMA-TOCOPHEROL | X-LINKED ADRENOLEUKODYSTROPHY | STATINS
Journal Article
JOURNAL OF LIPID RESEARCH, ISSN 0022-2275, 04/2019, Volume 60, Issue 4, pp. 892 - 899
Vitamin K (VK), in both its phylloquinone and menaquinone forms, has been hypothesized to undergo omega- and beta-oxidation on its hydrophobic side chain in... 
CATABOLISM | omega-oxidation | liquid chromatography-mass spectrometry | CYP4F2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | menaquinone | IDENTIFICATION | SUPPLEMENTATION | MENAQUINONE-4 | beta-oxidation | WARFARIN | phylloquinone | CALCIFICATION
Journal Article
METABOLIC ENGINEERING, ISSN 1096-7176, 03/2015, Volume 28, pp. 202 - 212
An engineered reversal of the beta-oxidation cycle was exploited to demonstrate its utility for the synthesis of medium chain (6-10-carbons) omega-hydroxyacids... 
omega-oxidation | Fuels and chemicals | FATTY-ACIDS | BIOCATALYSIS | PSEUDOMONAS-OLEOVORANS | SUBSTRATE-SPECIFICITY | CHEMICALS | PRODUCTS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ESCHERICHIA-COLI K-12 | Metabolic engineering | ALKANE-DEGRADATION | Synthetic biology | OXYFUNCTIONALIZATION | beta-oxidation reversal | CYCLE
Journal Article
Advanced Synthesis and Catalysis, ISSN 1615-4150, 06/2013, Volume 355, Issue 9, pp. 1693 - 1697
Journal Article
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, ISSN 0175-7598, 08/2017, Volume 101, Issue 16, pp. 6333 - 6342
alpha, omega-Dicarboxylic acids (DCAs) are multipurpose chemicals widely used in polymers, perfumes, plasticizers, lubricants, and adhesives. The... 
BETA-OXIDATION | CYP52 FAMILY | Candida sorbophila | YARROWIA-LIPOLYTICA | ESCHERICHIA-COLI | FATTY-ACIDS | IDENTIFICATION | PATHOGENICITY | INHIBITION | ATCC-20336 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | Biotransformation | Dicarboxylic acid | Chemostat enrichment culture | TROPICALIS | omega-Oxidation
Journal Article
ORGANIC PROCESS RESEARCH & DEVELOPMENT, ISSN 1083-6160, 06/2014, Volume 18, Issue 6, pp. 752 - 766
The worldwide market for biomaterials is projected to grow by a two-digit number annually over the next decade, a trend evoked predominantly by increasing... 
PSEUDOMONAS-OLEOVORANS | CANDIDA-TROPICALIS | ENZYMATIC OMEGA-OXIDATION | EPSILON-CAPROLACTONE | FUNCTIONAL EXPRESSION | ESCHERICHIA-COLI | CHEMISTRY, ORGANIC | FATTY-ACIDS | BAEYER-VILLIGER MONOOXYGENASES | CHEMISTRY, APPLIED | SACCHAROMYCES-CEREVISIAE | CORYNEBACTERIUM-GLUTAMICUM
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2017, Volume 7, Issue 1, p. 8369
An unprecedented method for the efficient conversion of C-3-C-12 linear alkanes to their corresponding primary alcohols mediated by the membrane-bound alkane... 
METHANE MONOOXYGENASE | PRE-EDGE | ENZYMATIC OMEGA-OXIDATION | RAY-ABSORPTION-SPECTROSCOPY | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | X-RAY | BUTANE OXIDATION | OLEOVORANS | 2-IRON RUBREDOXIN | MOLECULAR-OXYGEN
Journal Article
Frontiers in Plant Science, ISSN 1664-462X, 02/2012, Volume 3, pp. 19 - 19
The oxylipin hormone jasmonate controls myriad processes involved in plant growth, development, and immune function. The discovery of jasmonoyl-L-isoleucine... 
Lipid signaling | Plant hormone | Jasmonate | Arabidopsis | Cytochrome P450 | Omega oxidation | Oxylipin metabolism | Plant defense | plant hormone | plant defense | jasmonate | oxylipin metabolism | cytochrome P450 | lipid signaling | omega oxidation | PLANT SCIENCES | Fatty acid hydroxylase | Hormone catabolism
Journal Article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, ISSN 0021-8561, 09/2015, Volume 63, Issue 37, pp. 8199 - 8208
Long-chain alpha,omega-dicarboxylic acids (LDCAs, >= C12) are widely used as a raw material for preparing various commodities and polymers. In this study, a... 
omega-oxidation pathway | fatty acids | alpha,omega-dicarboxylic acids | FOOD SCIENCE & TECHNOLOGY | IDENTIFICATION | monooxygenase | MONOOXYGENASES | CANDIDA-TROPICALIS | DICARBOXYLIC-ACIDS | GENE | METABOLISM | ENZYMES | AGRICULTURE, MULTIDISCIPLINARY | HYDROGEN-PEROXIDE | CHEMISTRY, APPLIED | PROTEINS | EXPRESSION | CYP450s
Journal Article
Chest, ISSN 0012-3692, 08/2019, Volume 156, Issue 2, pp. 269 - 276
Journal Article
Hypertension, ISSN 0194-911X, 08/2015, Volume 66, Issue 2, pp. 422 - 429
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 05/2015, Volume 13, Issue 19, pp. 5412 - 5417
Lipid mediators have attracted great interest from scientists within the chemical, medicinal, and pharmaceutical research community. One such example is... 
LIPID MEDIATOR | POLYMORPHONUCLEAR LEUKOCYTES | CONJUGATE REDUCTION | PROPARGYLIC ALCOHOLS | CHEMISTRY, ORGANIC | ALPHA,BETA-UNSATURATED CARBONYL-COMPOUNDS | OMEGA-OXIDATION | ARACHIDONIC-ACID | PROTECTIN D1 | REDUCTIVE ELIMINATION | HYDRIDE
Journal Article
JOURNAL OF CLINICAL LIPIDOLOGY, ISSN 1933-2874, 06/2018, Volume 12, Issue 3, pp. 756 - 766
BACKGROUND: How hepatitis C virus (HCV)-associated lipid metabolic alterations recover after sustained virological response (SVR) remains elusive. OBJECTIVE:... 
Metabolomics | CARNITINE | omega-oxidation | VIRUS-INFECTION | Liquid chromatography-tandem mass spectrometry | Lathosterol | RISK | Lipid | GENOTYPES | MEDIUM-CHAIN | PATHWAY | LIVER | PHARMACOLOGY & PHARMACY | HCV | ERADICATION | CHOLESTEROL-SYNTHESIS
Journal Article
BIOTECHNOLOGY LETTERS, ISSN 0141-5492, 03/2017, Volume 39, Issue 3, pp. 429 - 438
To explore Candida guilliermondii for the production of long-chain dicarboxylic acids (DCA), we performed metabolic pathway engineering aiming to prevent DCA... 
Cytochrome P450 hydroxylase | DICARBOXYLIC-ACIDS | Oleic acid | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | beta-Oxidation | GENE-EXPRESSION | Genetic engineering | TROPICALIS | Acyl-CoA oxidase | omega-Oxidation | Long chain dicarboxylic acids | Consumption | Biotechnology | Pathways | Genes | Candida | Dicarboxylic acids | Metabolism | Fatty acids
Journal Article
Energy and Fuels, ISSN 0887-0624, 02/2017, Volume 31, Issue 2, pp. 1126 - 1135
Simulations of aerobic biodegradation have been widely employed to investigate the mechanisms of crude oil biodegradation in geological environments. In this... 
ENGINEERING, CHEMICAL | RESONANCE MASS-SPECTROMETRY | PETROLEUM BIODEGRADATION | DEEP SUBSURFACE | ENERGY & FUELS | CHAIN FATTY-ACIDS | NITROGEN-COMPOUNDS | LIAOHE BASIN | OMEGA-OXIDATION | POLAR NSO COMPOUNDS | PLASMID ALK REGULON | ELECTROSPRAY-IONIZATION
Journal Article
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