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International Journal of Molecular Sciences, ISSN 1661-6596, 10/2018, Volume 19, Issue 10
Journal Article
JNCCN Journal of the National Comprehensive Cancer Network, ISSN 1540-1405, 05/2018, Volume 16, Issue 5, pp. 467 - 472
Tumor DNA sequencing can identify rare driver genomic alterations that suggest targets for cancer therapy, even when these drivers cannot be suspected on... 
ONCOPROTEIN | OUTCOMES | MECHANISM | ONCOLOGY | INHIBITOR
Journal Article
Biochimica et Biophysica Acta - Reviews on Cancer, ISSN 0304-419X, 04/2014, Volume 1845, Issue 2, pp. 91 - 103
Cervical cancer is the second most common cancer among women worldwide and is responsible for 275,000 deaths each year. Persistent infection with high-risk... 
Oncoproteins | Biomarkers | Cervical cancer | HPV
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2015, Volume 112, Issue 32, pp. 9872 - 9877
Journal Article
Nature, ISSN 0028-0836, 01/2016, Volume 529, Issue 7587, pp. 541 - 545
Journal Article
CANCER CELL, ISSN 1535-6108, 07/2014, Volume 26, Issue 1, pp. 48 - 60
It is currently unclear whether Merlin/NF2 suppresses tumorigenesis by activating upstream components of the Hippo pathway at the plasma membrane or by... 
APOPTOSIS | ONCOLOGY | PHOSPHORYLATION | UBIQUITIN | TUMOR-SUPPRESSOR GENES | GROWTH | YAP ONCOPROTEIN | SIZE-CONTROL | PLASMA-MEMBRANE | CANCER | DROSOPHILA | CELL BIOLOGY
Journal Article
Human Pathology, ISSN 0046-8177, 2015, Volume 46, Issue 7, pp. 1068 - 1077
Summary ARID2 (ARID2), CTNNB1 (β catenin), tumor protein 53 (p53), and PIK3CA (p110α) mutations are implicated in hepatocellular carcinoma (HCC); and previous... 
Pathology | Immunohistochemistry | mTOR | Recurrence | Hepatocarcinogenesis | Oncoprotein
Journal Article
Journal of virology, ISSN 0022-538X, 02/2019, Volume 93, Issue 4
Human papillomaviruses (HPVs) are causative agents in ano-genital and oropharyngeal cancers. The virus must reprogram host gene expression to promote... 
oral keratinocytes | papillomavirus | host genome | head and neck cancer | transcription | TCGA | HEAD | ACTIVATION | PROTEIN | STAT1 | HPV16 E2 | NECK-CANCER | E6 ONCOPROTEIN | VIROLOGY | E7 ONCOPROTEIN | BINDING | GENOME EXPRESSION | Index Medicus
Journal Article
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, ISSN 1943-0264, 11/2009, Volume 1, Issue 5, pp. 169 - 182
NF-kappa B transcription factors have been suspected to be involved in cancer development since their discovery because of their kinship with the v-Rel... 
MULTIPLE-MYELOMA | HEPATOCELLULAR-CARCINOMA | ONCOPROTEIN BCL-3 | TRANSGENIC MOUSE | PROSTATE-CANCER | CHEMICAL HEPATOCARCINOGENESIS | COMPENSATORY PROLIFERATION | IKK-BETA | COLITIS-ASSOCIATED CANCER | INTESTINAL EPITHELIAL-CELLS | CELL BIOLOGY | 040
Journal Article
International Journal of Pharmacy and Pharmaceutical Sciences, 2015, Volume 7, Issue 3, pp. 278 - 284
Journal Article
Journal of Cancer, ISSN 1837-9664, 2019, Volume 10, Issue 13, pp. 2942 - 2952
Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent cancer worldwide. Long-term survival rates in patients with HNSCC have not increased... 
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 10/2018, Volume 36, Issue 30, pp. 3007 - 3014
PurposeBirabresib (MK-8628/OTX015) is a first-in-class bromodomain inhibitor with activity in select hematologic tumors. Safety, efficacy, and pharmacokinetics... 
CELL LUNG-CANCER | BET | ONCOPROTEIN | MECHANISM | EFFICACY | ONCOLOGY | OTX015 | PROSTATE-CANCER | RESISTANCE | MALIGNANCIES | CARCINOMA | Index Medicus
Journal Article
PLOS PATHOGENS, ISSN 1553-7366, 05/2014, Volume 10, Issue 5
Adenoviruses infect epithelial cells lining mucous membranes to cause acute diseases in people. They are also utilized as vectors for vaccination and for gene... 
PAPILLOMAVIRUS E6 ONCOPROTEINS | LARGE TUMOR-SUPPRESSOR | TAX ONCOPROTEIN | MICROBIOLOGY | TIGHT JUNCTIONS | VIROLOGY | EPITHELIAL-CELLS | VIRAL ONCOPROTEIN | PDZ-DOMAINS | COMMON TARGETS | HUMAN HOMOLOG | CELLULAR-TRANSFORMATION | PARASITOLOGY
Journal Article
Oncotarget, ISSN 1949-2553, 07/2019, Volume 10, Issue 46, pp. 4761 - 4775
Journal Article
Cancer Research, ISSN 0008-5472, 01/2019, Volume 79, Issue 1, pp. 209 - 219
In cancer, kinases are often activated and phosphatases suppressed, leading to aberrant activation of signaling pathways driving cellular proliferation,... 
OVEREXPRESSION | ONCOPROTEIN | PROTEIN | MECHANISM | ONCOLOGY | C-MYC | SUPPRESSOR PP2A | DRUG-RESISTANCE | CIP2A | COMBINATION | TUMORIGENESIS
Journal Article
Blood, ISSN 0006-4971, 03/2007, Volume 109, Issue 6, pp. 2293 - 2302
Whether resveratrol, a component of red grapes, berries, and peanuts, could suppress the proliferation of multiple myeloma (MM) cells by interfering with... 
THERAPY | CYCLIN D1 | BCL-X EXPRESSION | CONSTITUTIVE ACTIVATION | PROTEIN-KINASE | RESISTANCE | SRC ONCOPROTEIN | SUPPRESSION | HEMATOLOGY | TRANSCRIPTION FACTOR | CANCER
Journal Article
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