Shock, ISSN 1073-2322, 2014, Volume 41, Issue 1, pp. 3 - 11
Given that the leading clinical conditions associated with acute kidney injury (AKI), namely, sepsis, major surgery, heart failure, and hypovolemia, are all...
cell cycle | inflammation | microcirculation | Acute kidney injury | mitochondria | sepsis | SURGERY | OXIDATIVE STRESS | AUTOPHAGY CONTRIBUTES | PERITUBULAR CAPILLARY DYSFUNCTION | ORGAN BLOOD-FLOW | ACUTE-RENAL-FAILURE | HYPERDYNAMIC SEPSIS | NITRIC-OXIDE | SEPTIC SHOCK | MITOCHONDRIAL DYSFUNCTION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | CRITICALLY-ILL PATIENTS | CRITICAL CARE MEDICINE | Kidney Tubules - physiopathology | Humans | Adaptation, Physiological - physiology | Renal Circulation - physiology | Sepsis - complications | Sepsis - physiopathology | Acute Kidney Injury - physiopathology | Glomerular Filtration Rate - physiology | Microcirculation - physiology | Inflammation - complications | Animals | Energy Metabolism - physiology | Acute Kidney Injury - etiology
cell cycle | inflammation | microcirculation | Acute kidney injury | mitochondria | sepsis | SURGERY | OXIDATIVE STRESS | AUTOPHAGY CONTRIBUTES | PERITUBULAR CAPILLARY DYSFUNCTION | ORGAN BLOOD-FLOW | ACUTE-RENAL-FAILURE | HYPERDYNAMIC SEPSIS | NITRIC-OXIDE | SEPTIC SHOCK | MITOCHONDRIAL DYSFUNCTION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | CRITICALLY-ILL PATIENTS | CRITICAL CARE MEDICINE | Kidney Tubules - physiopathology | Humans | Adaptation, Physiological - physiology | Renal Circulation - physiology | Sepsis - complications | Sepsis - physiopathology | Acute Kidney Injury - physiopathology | Glomerular Filtration Rate - physiology | Microcirculation - physiology | Inflammation - complications | Animals | Energy Metabolism - physiology | Acute Kidney Injury - etiology
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2015, Volume 372, Issue 12, pp. 1138 - 1149
Fibrosis is a consequence of the inflammatory response. When fibrotic tissue becomes excessive, it can have diverse pathophysiological effects on a number of...
CONTROLLED CLINICAL-TRIAL | MEDICINE, GENERAL & INTERNAL | CARDIOVASCULAR MAGNETIC-RESONANCE | CHRONIC HEPATITIS-B | LIVER FIBROSIS | SKIN FIBROSIS | OPEN-LABEL | PLACEBO-CONTROLLED TRIAL | IDIOPATHIC PULMONARY-FIBROSIS | MESENCHYMAL TRANSITION | MOLECULAR-MECHANISMS | Fibrosis - therapy | Fibrosis - physiopathology | Transforming Growth Factor beta - metabolism | Fibrosis - complications | Humans | Multiple Organ Failure - etiology | Cell proliferation | Care and treatment | Fibrosis | Fibroblasts | Inflammation | Research | Risk factors | Proteins | Tissue | Medical research | Pathogenesis | Extracellular matrix
CONTROLLED CLINICAL-TRIAL | MEDICINE, GENERAL & INTERNAL | CARDIOVASCULAR MAGNETIC-RESONANCE | CHRONIC HEPATITIS-B | LIVER FIBROSIS | SKIN FIBROSIS | OPEN-LABEL | PLACEBO-CONTROLLED TRIAL | IDIOPATHIC PULMONARY-FIBROSIS | MESENCHYMAL TRANSITION | MOLECULAR-MECHANISMS | Fibrosis - therapy | Fibrosis - physiopathology | Transforming Growth Factor beta - metabolism | Fibrosis - complications | Humans | Multiple Organ Failure - etiology | Cell proliferation | Care and treatment | Fibrosis | Fibroblasts | Inflammation | Research | Risk factors | Proteins | Tissue | Medical research | Pathogenesis | Extracellular matrix
Journal Article
Nature Reviews Gastroenterology and Hepatology, ISSN 1759-5045, 02/2013, Volume 10, Issue 2, pp. 79 - 89
Ischaemia-reperfusion injury (IRI in the liver, a major complication of haemorrhagic shock, resection and transplantation, is a dynamic process that involves...
IMMUNE-RESPONSE | SELECTIN GLYCOPROTEIN LIGAND-1 | ORGAN PRESERVATION | INFLAMMATORY RESPONSES | COLD ISCHEMIA/REPERFUSION | MOLECULAR-PATTERN MOLECULES | T-CELL | GASTROENTEROLOGY & HEPATOLOGY | HEPATIC ISCHEMIA/REPERFUSION INJURY | ENDOGENOUS LIGANDS | TOLL-LIKE-RECEPTOR | Adaptive Immunity - physiology | Liver - blood supply | Animals | Immunity, Innate - physiology | Swine | Humans | Reperfusion Injury - physiopathology | Models, Animal | Signal Transduction - physiology | Liver - surgery | Liver - physiopathology | Liver Transplantation - physiology | Complications and side effects | Transplantation | Research | Liver | Reperfusion injury | Risk factors
IMMUNE-RESPONSE | SELECTIN GLYCOPROTEIN LIGAND-1 | ORGAN PRESERVATION | INFLAMMATORY RESPONSES | COLD ISCHEMIA/REPERFUSION | MOLECULAR-PATTERN MOLECULES | T-CELL | GASTROENTEROLOGY & HEPATOLOGY | HEPATIC ISCHEMIA/REPERFUSION INJURY | ENDOGENOUS LIGANDS | TOLL-LIKE-RECEPTOR | Adaptive Immunity - physiology | Liver - blood supply | Animals | Immunity, Innate - physiology | Swine | Humans | Reperfusion Injury - physiopathology | Models, Animal | Signal Transduction - physiology | Liver - surgery | Liver - physiopathology | Liver Transplantation - physiology | Complications and side effects | Transplantation | Research | Liver | Reperfusion injury | Risk factors
Journal Article
1998, Blackwell companions to philosophy., ISBN 0631197370, xv, 512
Book
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2010, Volume 76, Issue 3, pp. S94 - S100
The liver is a critically important organ that has numerous functions including the production of bile, metabolism of ingested nutrients, elimination of many...
Radiology | Hematology, Oncology and Palliative Medicine | Normal tissue toxicity | Liver | Radiation-induced liver disease | NORMAL-TISSUE | METASTASES | UNRESECTABLE HEPATOCELLULAR-CARCINOMA | THERAPY | HEPATIC TOXICITY | ONCOLOGY | STEREOTACTIC BODY RADIOTHERAPY | DISEASE | COMPLICATION PROBABILITY MODEL | 3-DIMENSIONAL CONFORMAL RADIOTHERAPY | PHASE-I | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Models, Biological | Humans | Liver Neoplasms - radiotherapy | Radiation Tolerance | Liver - radiation effects | Risk | Radiation Dosage | Radiation Injuries - complications | Liver Neoplasms - secondary | Radiation Injuries - therapy | Protein biosynthesis | Serum albumin | Radiotherapy | Glycogen | Radiation | INJURIES | NEOPLASMS | ESOPHAGUS | DIGESTIVE SYSTEM | RADIATION EFFECTS | MEDICINE | RADIATION INJURIES | NUCLEAR MEDICINE | ORGANS | ABDOMEN | DISEASES | GLANDS | BIOLOGICAL EFFECTS | LIVER | RADIOLOGY AND NUCLEAR MEDICINE | BIOLOGICAL RADIATION EFFECTS | RADIOTHERAPY | BODY | RADIOLOGY | normal tissue toxicity | radiation induced liver disease
Radiology | Hematology, Oncology and Palliative Medicine | Normal tissue toxicity | Liver | Radiation-induced liver disease | NORMAL-TISSUE | METASTASES | UNRESECTABLE HEPATOCELLULAR-CARCINOMA | THERAPY | HEPATIC TOXICITY | ONCOLOGY | STEREOTACTIC BODY RADIOTHERAPY | DISEASE | COMPLICATION PROBABILITY MODEL | 3-DIMENSIONAL CONFORMAL RADIOTHERAPY | PHASE-I | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Models, Biological | Humans | Liver Neoplasms - radiotherapy | Radiation Tolerance | Liver - radiation effects | Risk | Radiation Dosage | Radiation Injuries - complications | Liver Neoplasms - secondary | Radiation Injuries - therapy | Protein biosynthesis | Serum albumin | Radiotherapy | Glycogen | Radiation | INJURIES | NEOPLASMS | ESOPHAGUS | DIGESTIVE SYSTEM | RADIATION EFFECTS | MEDICINE | RADIATION INJURIES | NUCLEAR MEDICINE | ORGANS | ABDOMEN | DISEASES | GLANDS | BIOLOGICAL EFFECTS | LIVER | RADIOLOGY AND NUCLEAR MEDICINE | BIOLOGICAL RADIATION EFFECTS | RADIOTHERAPY | BODY | RADIOLOGY | normal tissue toxicity | radiation induced liver disease
Journal Article
Intensive Care Medicine, ISSN 0342-4642, 1/2004, Volume 30, Issue 1, pp. 51 - 61
To re-examine the epidemiology of acute lung injury (ALI) in European intensive care units (ICUs).A 2-month inception cohort study in 78 ICUs of 10 European...
Medicine | Acute respiratory distress syndrome | Positive pressure ventilation | Acute lung injury | Epidemiology | Mechanical ventilation | Barotrauma | MORTALITY | mechanical ventilation | CONSENSUS CONFERENCE | barotrauma | positive pressure ventilation | acute lung injury | RESPIRATORY-DISTRESS-SYNDROME | epidemiology | DEFINITIONS | acute respiratory distress syndrome | SYNDROME ARDS | MULTIVARIATE-ANALYSIS | CLINICAL RISK-FACTORS | SEVERITY | PULMONARY BAROTRAUMA | CRITICAL CARE MEDICINE | Critical Care - methods | Multivariate Analysis | Age Distribution | Prognosis | Prospective Studies | Humans | Middle Aged | Male | Tidal Volume | Incidence | Multiple Organ Failure - epidemiology | Respiratory Distress Syndrome, Adult - complications | Female | Length of Stay - statistics & numerical data | Respiratory Distress Syndrome, Adult - therapy | Severity of Illness Index | Intensive Care Units | Hospital Mortality | Europe - epidemiology | Logistic Models | Treatment Outcome | Disease Progression | Multiple Organ Failure - etiology | Survival Analysis | Aged | Respiratory Distress Syndrome, Adult - epidemiology | Causality | Population Surveillance | Care and treatment | Lung diseases | Risk factors
Medicine | Acute respiratory distress syndrome | Positive pressure ventilation | Acute lung injury | Epidemiology | Mechanical ventilation | Barotrauma | MORTALITY | mechanical ventilation | CONSENSUS CONFERENCE | barotrauma | positive pressure ventilation | acute lung injury | RESPIRATORY-DISTRESS-SYNDROME | epidemiology | DEFINITIONS | acute respiratory distress syndrome | SYNDROME ARDS | MULTIVARIATE-ANALYSIS | CLINICAL RISK-FACTORS | SEVERITY | PULMONARY BAROTRAUMA | CRITICAL CARE MEDICINE | Critical Care - methods | Multivariate Analysis | Age Distribution | Prognosis | Prospective Studies | Humans | Middle Aged | Male | Tidal Volume | Incidence | Multiple Organ Failure - epidemiology | Respiratory Distress Syndrome, Adult - complications | Female | Length of Stay - statistics & numerical data | Respiratory Distress Syndrome, Adult - therapy | Severity of Illness Index | Intensive Care Units | Hospital Mortality | Europe - epidemiology | Logistic Models | Treatment Outcome | Disease Progression | Multiple Organ Failure - etiology | Survival Analysis | Aged | Respiratory Distress Syndrome, Adult - epidemiology | Causality | Population Surveillance | Care and treatment | Lung diseases | Risk factors
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 06/2019, Volume 234, Issue 6, pp. 7695 - 7707
Cerebral ischemia/reperfusion injury (CIRI) leads to injury in distant organs, most commonly the lungs, although limited studies have examined self‐protective...
cerebral ischemia/reperfusion injury | nuclear factor erythroid‐related factor 2 | antioxidative stress | acute lung injury | angiogenesis | nuclear factor erythroid-related factor 2 | PHYSIOLOGY | INDUCIBLE FACTOR-I | PROTECTION | LIMB ISCHEMIA-REPERFUSION | INVOLVEMENT | MICROVESSEL DENSITY | INDUCTION | CELL BIOLOGY | SYSTEMIC INFLAMMATORY RESPONSE | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | ERK | Immunohistochemistry | Oxidative stress | Reverse transcription | Kinases | Tissues | Subgroups | Proteins | Angiogenesis | Reperfusion | Ischemia | Heme | Thiobarbituric acid | Repair | Vascular endothelial growth factor | Growth factors | Malonaldehyde | CD34 antigen | Organs | Extracellular signal-regulated kinase | Gene expression | 1-Phosphatidylinositol 3-kinase | Polymerase chain reaction | Oxygenase | Injury prevention | Lungs | Nitric oxide | Hypoxia | Nuclear reactions
cerebral ischemia/reperfusion injury | nuclear factor erythroid‐related factor 2 | antioxidative stress | acute lung injury | angiogenesis | nuclear factor erythroid-related factor 2 | PHYSIOLOGY | INDUCIBLE FACTOR-I | PROTECTION | LIMB ISCHEMIA-REPERFUSION | INVOLVEMENT | MICROVESSEL DENSITY | INDUCTION | CELL BIOLOGY | SYSTEMIC INFLAMMATORY RESPONSE | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | ERK | Immunohistochemistry | Oxidative stress | Reverse transcription | Kinases | Tissues | Subgroups | Proteins | Angiogenesis | Reperfusion | Ischemia | Heme | Thiobarbituric acid | Repair | Vascular endothelial growth factor | Growth factors | Malonaldehyde | CD34 antigen | Organs | Extracellular signal-regulated kinase | Gene expression | 1-Phosphatidylinositol 3-kinase | Polymerase chain reaction | Oxygenase | Injury prevention | Lungs | Nitric oxide | Hypoxia | Nuclear reactions
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 03/2007, Volume 7, Issue 3, pp. 518 - 526
The 8th Banff Conference on Allograft Pathology was held in Edmonton, Canada, 15-21 July 2005. Major outcomes included the elimination of the non-specific term...
Banff classification | central slide review | scoring | Scoring | Central slide review | SURGERY | CYCLOSPORINE NEPHROTOXICITY | C4D DEPOSITS | HISTOLOGIC-FINDINGS | INCOMPATIBLE RENAL-ALLOGRAFTS | INTERTUBULAR CAPILLARY CHANGES | TRANSPLANTATION | PERITUBULAR CAPILLARIES | POSITIVE CROSS-MATCH | KIDNEY-TRANSPLANTATION | TRANSPLANT GLOMERULOPATHY | HUMORAL REJECTION | Diagnosis, Differential | Kidney Failure, Chronic - diagnosis | Kidney - pathology | Humans | Kidney - immunology | Organ Transplantation | Kidney Transplantation | Genetic Markers | Graft Rejection - diagnosis | Kidney Failure, Chronic - genetics | B-Lymphocytes - immunology | Kidney Failure, Chronic - pathology | Fibrosis | Antibodies - immunology | Graft Rejection - genetics | Chronic Disease | Graft Rejection - pathology
Banff classification | central slide review | scoring | Scoring | Central slide review | SURGERY | CYCLOSPORINE NEPHROTOXICITY | C4D DEPOSITS | HISTOLOGIC-FINDINGS | INCOMPATIBLE RENAL-ALLOGRAFTS | INTERTUBULAR CAPILLARY CHANGES | TRANSPLANTATION | PERITUBULAR CAPILLARIES | POSITIVE CROSS-MATCH | KIDNEY-TRANSPLANTATION | TRANSPLANT GLOMERULOPATHY | HUMORAL REJECTION | Diagnosis, Differential | Kidney Failure, Chronic - diagnosis | Kidney - pathology | Humans | Kidney - immunology | Organ Transplantation | Kidney Transplantation | Genetic Markers | Graft Rejection - diagnosis | Kidney Failure, Chronic - genetics | B-Lymphocytes - immunology | Kidney Failure, Chronic - pathology | Fibrosis | Antibodies - immunology | Graft Rejection - genetics | Chronic Disease | Graft Rejection - pathology
Journal Article
JAMA, ISSN 0098-7484, 09/2017, Volume 318, Issue 12, pp. 1198 - 1198
Electric current may cause local damage to the skin or muscle and may involve other organs, such as the heart. Electrical injury may result from contact with...
Electric Injuries - prevention & control | Humans | Electric Injuries - therapy | Medical personnel | Heart | Damage assessment | Intravenous administration | Electric contacts | Cardiac muscle | Medical treatment | Organs | Machinery | Doctors | Electrical currents | Prevention | Wiring | Electric appliances | Electric power | Skin | Household appliances | Heart diseases | Injuries | Burns (injuries) | Resuscitation | Power lines
Electric Injuries - prevention & control | Humans | Electric Injuries - therapy | Medical personnel | Heart | Damage assessment | Intravenous administration | Electric contacts | Cardiac muscle | Medical treatment | Organs | Machinery | Doctors | Electrical currents | Prevention | Wiring | Electric appliances | Electric power | Skin | Household appliances | Heart diseases | Injuries | Burns (injuries) | Resuscitation | Power lines
Journal Article
Critical Care Medicine, ISSN 0090-3493, 04/2011, Volume 39, Issue 4, pp. 818 - 826
OBJECTIVE:Aspiration of oropharyngeal or gastric contents into the lower respiratory tract is a common event in critically ill patients and can lead to...
acute respiratory distress syndrome | aspiration pneumonia | intensive care unit | acute lung injury | aspiration pneumonitis | aspiration | VENTILATOR-ASSOCIATED PNEUMONIA | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | NECROSIS-FACTOR-ALPHA | PULMONARY GRANULOMA-FORMATION | LIPID-LADEN MACROPHAGES | aspiration pneumonia, acute lung injury | RESPIRATORY-DISTRESS-SYNDROME | SYSTEMIC ORGAN INJURY | NURSING-HOME RESIDENTS | INTENSIVE-CARE-UNIT | acute respiratory distress syndrome, intensive care unit | ACID ASPIRATION | CRITICAL CARE MEDICINE | Biomarkers - metabolism | Humans | Risk Factors | Lung Injury - diagnosis | Lung Injury - etiology | Lung Injury - therapy | Respiratory Aspiration - epidemiology | Animals | Respiratory Aspiration - complications | Pneumonia, Aspiration - etiology | Respiratory Aspiration - diagnosis | Respiratory Aspiration - therapy | Disease Models, Animal | Aspiration
acute respiratory distress syndrome | aspiration pneumonia | intensive care unit | acute lung injury | aspiration pneumonitis | aspiration | VENTILATOR-ASSOCIATED PNEUMONIA | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | NECROSIS-FACTOR-ALPHA | PULMONARY GRANULOMA-FORMATION | LIPID-LADEN MACROPHAGES | aspiration pneumonia, acute lung injury | RESPIRATORY-DISTRESS-SYNDROME | SYSTEMIC ORGAN INJURY | NURSING-HOME RESIDENTS | INTENSIVE-CARE-UNIT | acute respiratory distress syndrome, intensive care unit | ACID ASPIRATION | CRITICAL CARE MEDICINE | Biomarkers - metabolism | Humans | Risk Factors | Lung Injury - diagnosis | Lung Injury - etiology | Lung Injury - therapy | Respiratory Aspiration - epidemiology | Animals | Respiratory Aspiration - complications | Pneumonia, Aspiration - etiology | Respiratory Aspiration - diagnosis | Respiratory Aspiration - therapy | Disease Models, Animal | Aspiration
Journal Article