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Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2012, Volume 55, Issue 10, pp. 4740 - 4763
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 09/2014, Volume 78, Issue 3, pp. 587 - 598
AIMS Rosuvastatin and pitavastatin have been proposed as probe substrates for the organic anion-transporting polypeptide (OATP) 1B, but clinical data on their... 
organic anion‐transporting polypeptide | regulatory guidance | breast cancer resistance protein | pitavastatin | rosuvastatin | drug–drug interactions | drug-drug interactions | organic anion-transporting polypeptide 1B | RIFAMPICIN | DRUG-DRUG INTERACTION | HEPATIC-CLEARANCE | P-GLYCOPROTEIN | ATORVASTATIN | INHIBITION | PHARMACOKINETICS | HUMAN HEPATOCYTES | PHARMACOLOGY & PHARMACY | HEALTHY-VOLUNTEERS | METABOLIZING-ENZYMES | Fluorobenzenes - pharmacokinetics | Organic Anion Transporters, Sodium-Independent - antagonists & inhibitors | Area Under Curve | Humans | Middle Aged | Male | Hepatocytes - metabolism | Organic Anion Transporters - metabolism | Quinolines - pharmacokinetics | Young Adult | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Drug Interactions | Organic Anion Transporters, Sodium-Independent - metabolism | Adult | Female | Rifampin - administration & dosage | Hepatocytes - drug effects | Solute Carrier Organic Anion Transporter Family Member 1B3 | Organic Anion Transporters - antagonists & inhibitors | Administration, Oral | Rosuvastatin Calcium | Sulfonamides - pharmacokinetics | Cross-Over Studies | Administration, Intravenous | Pyrimidines - pharmacokinetics | Rifampin - pharmacology | Solute Carrier Organic Anion Transporter Family Member 1b1 | Rosuvastatin | Drug resistance | Investigations | Antilipemic agents | Index Medicus | Drug Metabolism
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 09/2019, Volume 379, pp. 114649 - 114649
Organic anion-transporting polypeptides (human OATPs; animals Oatps; gene symbol ) are integral membrane proteins that mediate the sodium-independent transport... 
Organic anion transporting polypeptides | Macrolides | Tetracyclines | β-Lactams | Pig | Index Medicus
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 09/2019, Volume 378, pp. 114642 - 114642
Organic anion transporting polypeptides (OATPs) are key players of drug absorption, distribution and excretion due to their broad substrate specificity, wide... 
Uptake function | Protein stability | Transmembrane domains | Organic anion transporting polypeptides | Amino-terminus | ACID-RESIDUES | DISPOSITION | OATP1B1 | KINETICS | ESTRONE-3-SULFATE | SUPERFAMILY | PHARMACOLOGY & PHARMACY | TOXICOLOGY | BINDING | DRUG-DRUG INTERACTIONS
Journal Article
Journal Article
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 05/2018, Volume 46, Issue 5, pp. 652 - 657
Journal Article