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Nature Reviews Drug Discovery, ISSN 1474-1776, 2014, Volume 13, Issue 3, pp. 197 - 216
The nuclear receptors REV-ERB (consisting of REV-ERB alpha and REV-ERB beta) and retinoic acid receptor-related orphan receptors (RORs; consisting of ROR... 
KAPPA-B ACTIVATION | RETINOIC ACID | PERIPHERAL CIRCADIAN CLOCKS | SKELETAL-MUSCLE CELLS | URSOLIC ACID PROMOTES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | X-RAY-STRUCTURE | GENE-EXPRESSION | ORPHAN RECEPTOR | PHARMACOLOGY & PHARMACY | LIGAND-BINDING DOMAIN | T(H)17 CELL-DIFFERENTIATION | Neoplasms - metabolism | Nuclear Receptor Subfamily 1, Group D, Member 1 - chemistry | Humans | Receptors, Retinoic Acid - chemistry | Nuclear Receptor Subfamily 1, Group D, Member 1 - antagonists & inhibitors | Nuclear Receptor Subfamily 1, Group F, Member 1 - metabolism | Receptors, Cytoplasmic and Nuclear - chemistry | Nuclear Receptor Subfamily 1, Group D, Member 1 - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 1 - chemistry | Atherosclerosis - drug therapy | Diabetes Mellitus - drug therapy | Diabetes Mellitus - metabolism | Receptors, Retinoic Acid - antagonists & inhibitors | Receptors, Retinoic Acid - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 1 - antagonists & inhibitors | Atherosclerosis - metabolism | Neoplasms - drug therapy | Animals | Signal Transduction - drug effects | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Ligands | Signal Transduction - physiology | Drug Delivery Systems - trends | Drug Delivery Systems - methods | Receptors, Cytoplasmic and Nuclear - metabolism | Drug targeting | Cell receptors | Pharmacology, Experimental | Research | Properties
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2014, Volume 72, pp. 104 - 116
Abstract Nuclear receptors have generated substantial interest in the past decade as potential therapeutic targets for the treatment of neurodegenerative... 
Neurology | Parkinson's disease | Liver X receptors | Neurodegeneration | Amyotrophic lateral sclerosis | Inflammation | Peroxisome proliferator-activated receptors | Nuclear receptors | Retinoid X receptors | Huntington's disease | Alzheimer's disease | Microglia | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | PROLIFERATOR-ACTIVATED RECEPTORS | FOCAL CEREBRAL-ISCHEMIA | PROTECTS DOPAMINERGIC-NEURONS | AMYOTROPHIC-LATERAL-SCLEROSIS | NEUROSCIENCES | PROTEIN/PRESENILIN 1 MICE | CENTRAL-NERVOUS-SYSTEM | TRANSGENIC MOUSE MODEL | PPAR-GAMMA AGONIST | LIVER-X-RECEPTOR | Microglia - metabolism | Signal Transduction | Humans | Rats | Neurodegenerative Diseases - metabolism | Orphan Nuclear Receptors - metabolism | Huntington Disease - metabolism | Animals | Liver X Receptors | Alzheimer Disease - metabolism | Peroxisome Proliferator-Activated Receptors - metabolism | Mice | Nuclear Receptor Subfamily 4, Group A, Member 2 - metabolism | Parkinson Disease - metabolism | Retinoid X Receptors - metabolism | Disease Models, Animal | Receptors, Cytoplasmic and Nuclear - metabolism | Nervous system diseases | Analysis | nuclear receptors | Alzheimer’s disease | peroxisome proliferator-activated receptors | inflammation | liver X receptors | neurodegeneration | retinoid X receptors | Huntington’s disease | microglia | amyotrophic lateral sclerosis | Parkinson’s disease
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 8/2011, Volume 119, Issue 8, pp. 1142 - 1148
Background: The large and increasing number of chemicals released into the environment demands more efficient and cost-effective approaches for assessing... 
Chemical hazards | Receptors | Genomics | Environmental health | Agonists | Ligands | Cytotoxicity | Libraries | Environmental agencies | Research | Nuclear receptors | Chemical genomics | qHTS | Assay performance | Tox21 | assay performance | TOXICITY | ANTAGONISM | IDENTIFICATION | ESTROGEN-RECEPTOR | nuclear receptors | ENVIRONMENTAL SCIENCES | IN-VITRO | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | EVOLUTION | DISEASE | ASSAYS | SUPERFAMILY | HEALTH | chemical genomics | cytotoxicity | Peroxisome Proliferator-Activated Receptors - agonists | Cell Line | Retinoid X Receptor alpha - metabolism | Peroxisome Proliferator-Activated Receptors - antagonists & inhibitors | Humans | Orphan Nuclear Receptors - agonists | Receptors, Androgen - metabolism | Receptors, Cytoplasmic and Nuclear - agonists | Orphan Nuclear Receptors - metabolism | PPAR gamma - metabolism | Receptors, Thrombin - antagonists & inhibitors | Retinoid X Receptor alpha - agonists | Fragile X Mental Retardation Protein | Orphan Nuclear Receptors - antagonists & inhibitors | Retinoid X Receptor alpha - antagonists & inhibitors | PPAR gamma - antagonists & inhibitors | Receptors, Thrombin - agonists | Liver X Receptors | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Peroxisome Proliferator-Activated Receptors - metabolism | Receptors, Thrombin - metabolism | Estrogen Receptor alpha - metabolism | Environmental Pollutants - toxicity | Receptors, Cytoplasmic and Nuclear - metabolism | Environmental aspects | Physiological aspects | Cell receptors | Health aspects | Chemicals | Index Medicus
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 11/2017, Volume 74, Issue 22, pp. 4097 - 4120
In the central nervous system, embryonic and adult neural stem/progenitor cells (NSCs) generate the enormous variety and huge numbers of neuronal and glial... 
Biomedicine, general | Biochemistry, general | Agonists/antagonists | Brain development | Neurogenesis | Glucocorticoid | Cell Biology | Life Sciences | Neurological diseases | Life Sciences, general | Drug targets | Astrogliogenesis | Retinoic acid | PROLIFERATOR-ACTIVATED RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | VITAMIN-D-RECEPTOR | ORPHAN RECEPTOR | STEROIDOGENIC FACTOR-I | MINERALOCORTICOID RECEPTOR | CELL BIOLOGY | GLUCOCORTICOID-RECEPTOR | EMBRYONIC STEM-CELLS | CENTRAL-NERVOUS-SYSTEM | RETINOID-X-RECEPTOR | THYROID-HORMONE RECEPTOR | Receptors, Estrogen - metabolism | Receptors, Mineralocorticoid - metabolism | Humans | Receptors, Glucocorticoid - metabolism | Receptors, Calcitriol - metabolism | Neural Stem Cells - cytology | Receptors, Thyroid Hormone - metabolism | Animals | Nervous System Diseases - metabolism | Cell Differentiation | Neural Stem Cells - metabolism | Nervous System Diseases - pathology | Receptors, Cytoplasmic and Nuclear - metabolism | Medical research | Embryonic development | Nervous system diseases | Corticosteroids | Neurons | Homeostasis | Medicine, Experimental | Brain | Spinal cord | Regulators | Pathogenesis | Central nervous system | Nervous system | Glial cells | Nuclear receptors | Orphan nuclear receptors | Neuronal-glial interactions | Embryonic growth stage | Receptors | Embryogenesis | Molecular modelling | Cells (biology) | Stem cells | Neural stem cells | Receptor mechanisms | Aberration | Bile | Structure-function relationships
Journal Article