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1. Full Text Information and communication technology overload and social networking service fatigue: A stress perspective
by Lee, Ae Ri and Son, Soo-Min and Kim, Kyung Kyu
Computers in Human Behavior, ISSN 0747-5632, 02/2016, Volume 55, pp. 51 - 61
In an always connected communication environment, users of social networking services (SNSs) need to pay continuous attention to the overwhelming volume of... 
SNS | Communication overload | Information overload | SNS fatigue | ICT overload | System feature overload | FACEBOOK | TURNOVER | PSYCHOLOGY, EXPERIMENTAL | PSYCHOLOGY, MULTIDISCIPLINARY | SATISFACTION | ORGANIZATIONS | CONSEQUENCES | WORK | ANTECEDENTS | JOB | USERS | TECHNOSTRESS | Stress (Psychology) | Social networks | Fatigue
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2. Full Text Iron and oxidative stress in cardiomyopathy in thalassemia
by Berdoukas, Vasilios and Coates, Thomas D and Cabantchik, Zvi Ioav
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2015, Volume 88, Issue Pt A, pp. 3 - 9
With repeated blood transfusions, patients with thalassemia major rapidly become loaded with iron, often surpassing hepatic metal accumulation capacity within... 
Iron overload | Reactive oxygen species | Labile plasma iron | Transfusion | Iron chelation therapy | Free radicals | Thalassemia major | Iron cardiomyopathy | Labile cellular iron | OVERLOAD | BIOCHEMISTRY & MOLECULAR BIOLOGY | TOXICITY | RANDOMIZED CONTROLLED-TRIAL | MYOCARDIAL IRON | Iron cardionayopathy | TRANSFERRIN-BOUND IRON | LABILE IRON | DEFEROXAMINE | ENDOCRINOLOGY & METABOLISM | DEFERIPRONE | CALCIUM-CHANNEL | CHELATION | Iron Chelating Agents - therapeutic use | Transferrin | Iron Overload - drug therapy | Humans | Cardiomyopathies - prevention & control | Cardiomyopathies - etiology | Iron Overload - physiopathology | Iron Overload - etiology | Cardiomyopathies - physiopathology | Iron Overload - complications | Thalassemia - complications | Oxidative Stress - drug effects | Thalassemia - physiopathology | Oxidative stress | Enzymes | Calcium channels | Implants, Artificial | Prosthesis | Cardiac patients | Physiological aspects | Thalassemia | Mitochondrial DNA | Index Medicus
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3. Full Text The Impact of Mental Representations on ICT-Related Overload in the Use of Mobile Phones
by Saunders, Carol and Wiener, Martin and Klett, Sabrina and Sprenger, Sebastian
Journal of Management Information Systems, ISSN 0742-1222, 07/2017, Volume 34, Issue 3, pp. 803 - 825
The use of information and communication technology (ICT) can be accompanied by the epiphenomenon of ICT-related overload, or the emotional and cognitive state... 
communication overload | information overload | mental representations | ICT-related overload | cognitive overload | mobile phone use | emotional overload | feature overload | polychronicity | DECISION | MANAGEMENT | LOAD | MULTITASKING | COMPUTER SCIENCE, INFORMATION SYSTEMS | BEHAVIORAL-RESEARCH | INDIVIDUALS | ORGANIZATIONS | PLS | INFORMATION SCIENCE & LIBRARY SCIENCE | SEM | TECHNOSTRESS
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4. Full Text Lack of the bone morphogenetic protein BMP6 induces massive iron overload
by Meynard, Delphine and Kautz, Léon and Darnaud, Valérie and Canonne-Hergaux, François and Coppin, Hélène and Roth, Marie-Paule
Nature Genetics, ISSN 1061-4036, 04/2009, Volume 41, Issue 4, pp. 478 - 481
Expression of hepcidin, a key regulator of intestinal iron absorption, can be induced in vitro by several bone morphogenetic proteins (BMPs), including BMP2,... 
TFR2 | FERROPORTIN | MEMBRANE | HFE | GENETICS & HEREDITY | HEPCIDIN | MICE | MODEL | EXPRESSION | HEMOJUVELIN | HEMOCHROMATOSIS | Liver - pathology | Iron Overload - genetics | Humans | RNA, Messenger - genetics | Gene Expression Regulation | Bone Morphogenetic Protein 6 - deficiency | Iron Overload - pathology | Iron - metabolism | Mice, Knockout | Animals | Bone Morphogenetic Protein 6 - genetics | Iron Overload - metabolism | Spleen - metabolism | Mice | Messenger RNA | Physiological aspects | Bone morphogenetic proteins | Iron metabolism disorders | Genetic aspects | Cellular signal transduction | Research | Health aspects | Risk factors | Proteins | Mathematical models | Infrared imaging systems | Kinases | Rodents | Cells | Spleen | Bone Morphogenetic Protein 6 | Liver | Iron | Cellular Biology | Life Sciences | RNA, Messenger | Iron Overload
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5. Full Text Elevated liver iron concentration is a marker of increased morbidity in patients with β thalassemia intermedia
by Khaled M. Musallam and Maria Domenica Cappellini and John C. Wood and Irene Motta and Giovanna Graziadei and Hani Tamim and Ali T. Taher
Haematologica, ISSN 0390-6078, 11/2011, Volume 96, Issue 11, pp. 1605 - 1612
Background Patients with beta thalassemia intermedia can have substantial iron overload, irrespectively of their transfusion status, secondary to increased... 
Iron overload | Vascular disease | Osteoporosis | Thalassemia intermedia | Liver iron concentration | Endocrine disease | OVERLOAD | iron overload | endocrine disease | PULMONARY ARTERIAL-HYPERTENSION | INEFFECTIVE ERYTHROPOIESIS | osteoporosis | thalassemia intermedia | SERUM FERRITIN | HYPERCOAGULABLE STATE | HEART-DISEASE | liver iron concentration | vascular disease | CHELATING THERAPY | SPLENECTOMIZED PATIENTS | MAGNETIC-RESONANCE | SICKLE-CELL-DISEASE | HEMATOLOGY | Blood Platelets - pathology | beta-Thalassemia - pathology | Liver - pathology | Iron Overload - mortality | Humans | Middle Aged | Male | Erythrocytes, Abnormal - metabolism | Iron Overload - pathology | beta-Thalassemia - mortality | Splenectomy | Blood Transfusion | Ferritins - blood | Iron Overload - metabolism | Adult | Female | Fetal Hemoglobin - metabolism | Biomarkers - metabolism | Cross-Sectional Studies | Liver - metabolism | Iron - metabolism | Erythrocytes, Abnormal - pathology | Platelet Count | Blood Platelets - metabolism | beta-Thalassemia - metabolism | Erythrocyte Count | Original Research
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6. Full Text Identification of erythroferrone as an erythroid regulator of iron metabolism
by Kautz, Léon and Jung, Grace and Valore, Erika V and Rivella, Stefano and Nemeth, Elizabeta and Ganz, Tomas
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 7, pp. 678 - 684
Recovery from blood loss requires a greatly enhanced supply of iron to support expanded erythropoiesis. After hemorrhage, suppression of the iron-regulatory... 
OVERLOAD | HOMEOSTASIS | DIFFERENTIATION FACTOR 15 | BETA-THALASSEMIA-INTERMEDIA | ERYTHROPOIESIS | GENETICS & HEREDITY | MOUSE-LIVER | MICE | HEPCIDIN EXPRESSION | ANEMIA | HYPOXIA | Hepcidins - metabolism | beta-Thalassemia - pathology | Liver - pathology | Iron Overload - drug therapy | Molecular Sequence Data | Erythropoiesis - drug effects | Male | Gene Expression Profiling | Iron Overload - pathology | Iron Overload - metabolism | Epoetin Alfa | Erythropoietin - metabolism | Real-Time Polymerase Chain Reaction | Anemia - etiology | Disease Models, Animal | Recombinant Proteins - metabolism | Hormones - pharmacology | Enzyme-Linked Immunosorbent Assay | Liver - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Hemorrhage - complications | Hemoglobins - metabolism | Hemorrhage - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Iron - metabolism | Blotting, Western | Erythropoiesis - physiology | Mice, Knockout | Anemia - metabolism | Animals | Mice | beta-Thalassemia - metabolism | Physiological aspects | Genetic research | Genetic aspects | Iron in the body | Hormones | Research | Genetic regulation | Identification and classification | Flow cytometry | Plasma | Phosphorylation | Bone marrow | Homeostasis | Iron | Grants | Metabolism | Gene expression | Experiments | Hemorrhage
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7. Full Text Ferroportin disease: Pathogenesis, diagnosis and treatment
by Pietrangelo, Antonello
Haematologica, ISSN 0390-6078, 11/2017, Volume 102, Issue 12, pp. 1972 - 1984
Ferroportin Disease (FD) is an autosomal dominant hereditary iron loading disorder associated with heterozygote mutations of the ferroportin-1 (FPN) gene. It... 
MOLECULAR-MECHANISM | PRIMARY IRON OVERLOAD | AFRICAN-AMERICAN MAN | SLC40A1 GENE | JUVENILE HEMOCHROMATOSIS | MISSENSE MUTATION | FUNCTIONAL-ANALYSIS | AUTOSOMAL-DOMINANT HEMOCHROMATOSIS | HEREDITARY HEMOCHROMATOSIS | HEMATOLOGY | RESPONSIVE ELEMENT | Kupffer Cells - pathology | Iron Overload - genetics | Humans | Iron Overload - therapy | Phlebotomy | Cation Transport Proteins - genetics | Mutation | Iron Overload - pathology | Iron Overload - diagnosis | Review
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8. Full Text Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non–transferrin-bound iron
by Stefanova, Deborah and Raychev, Antoan and Arezes, Joao and Ruchala, Piotr and Gabayan, Victoria and Skurnik, Mikael and Dillon, Barbara J and Horwitz, Marcus A and Ganz, Tomas and Bulut, Yonca and Nemeth, Elizabeta
Blood, ISSN 0006-4971, 07/2017, Volume 130, Issue 3, pp. 245 - 257
The iron-regulatory hormone hepcidin is induced early in infection, causing iron sequestration in macrophages and decreased plasma iron; this is proposed to... 
OVERLOAD | MENINGITIS | VIBRIO-VULNIFICUS | DEFEROXAMINE | YERSINIA-ENTEROCOLITICA | TUBERCULOSIS | SUSCEPTIBILITY | STAPHYLOCOCCUS-AUREUS | VIRULENCE | HEMATOLOGY | HEMOCHROMATOSIS | Iron Overload - mortality | Catheter-Related Infections - metabolism | Yersinia enterocolitica - drug effects | Humans | Iron Overload - immunology | Hemochromatosis - metabolism | Mycobacterium tuberculosis - drug effects | Transferrin - genetics | Iron Overload - microbiology | Hemochromatosis - microbiology | Iron Overload - metabolism | Hepcidins - immunology | Catheter-Related Infections - mortality | Hepcidins - agonists | Staphylococcal Infections - microbiology | Mycobacterium tuberculosis - metabolism | Staphylococcus aureus | Disease Models, Animal | Staphylococcal Infections - metabolism | Binding, Competitive | Gene Expression | Disease Resistance | Staphylococcal Infections - immunology | Mice, Inbred C57BL | Iron - immunology | Iron - metabolism | Mice, Knockout | Staphylococcal Infections - mortality | Animals | Catheter-Related Infections - microbiology | Survival Analysis | Yersinia enterocolitica - metabolism | Catheter-Related Infections - immunology | Hemochromatosis - immunology | Hepcidins - genetics | Protein Binding | Yersinia enterocolitica - growth & development | Hemochromatosis - mortality | Hepcidins - deficiency | Mice | Oligopeptides - pharmacology | Transferrin - metabolism | Mycobacterium tuberculosis - growth & development | Plenary Paper
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9. Full Text Transcription factor NRF2 protects mice against dietary iron-induced liver injury by preventing hepatocytic cell death
by Silva-Gomes, Sandro and Santos, Ana G and Caldas, Carolina and Silva, Cátia M and Neves, João V and Lopes, Joanne and Carneiro, Fátima and Rodrigues, Pedro N and Duarte, Tiago L
Journal of Hepatology, ISSN 0168-8278, 2013, Volume 60, Issue 2, pp. 354 - 361
Background & Aims The liver, being the major site of iron storage, is particularly exposed to the toxic effects of iron. Transcription factor NRF2 is critical... 
Gastroenterology and Hepatology | Mito-TEMPOL | Hemochromatosis | 8-Hydroxy-2′-deoxyguanosine | Hepatocyte | Antioxidant | Necrosis | 8-Hydroxy-2′- deoxyguanosine | OVERLOAD | APOPTOSIS | OXIDATIVE STRESS | FERRIC NITRILOTRIACETATE | 8-Hydroxy-2'-deoxyguanosine | PLASMA | METABOLISM | PATHWAY | ONCOTIC NECROSIS | MITOCHONDRIAL DYSFUNCTION | GASTROENTEROLOGY & HEPATOLOGY | Liver - pathology | Iron Overload - drug therapy | Mitochondria, Liver - metabolism | Liver - metabolism | Mice, Inbred C57BL | Hepatocytes - pathology | Male | Antioxidants - pharmacology | Hepatocytes - metabolism | Spin Labels | Iron Overload - pathology | NF-E2-Related Factor 2 - deficiency | Iron, Dietary - toxicity | Mice, Knockout | Liver - injuries | Mitochondria, Liver - drug effects | Animals | Iron Overload - metabolism | Cyclic N-Oxides - pharmacology | NF-E2-Related Factor 2 - metabolism | NF-E2-Related Factor 2 - genetics | Mice | Hepatocytes - drug effects | Disease Models, Animal | Prevention | Iron | Liver diseases | Cell death | Liver | Index Medicus
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10. Full Text Iron overload cardiomyopathy: Better understanding of an increasing disorder
by Gujja, Pradeep and Rosing, Douglas R and Tripodi, Dorothy J and Shizukuda, Yukitaka
Journal of the American College of Cardiology, ISSN 0735-1097, 09/2010, Volume 56, Issue 13, pp. 1001 - 1012
The prevalence of iron overload cardiomyopathy (IOC) is increasing. The spectrum of symptoms of IOC is varied. Early in the disease process, patients may be... 
iron overload cardiomyopathy | calcium channel blockers | T2 MRI | chelation | hemochromatosis | hemosiderosis | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIAC IRON | BONE-MARROW-TRANSPLANTATION | MYOCARDIAL IRON | HEREDITARY HEMOCHROMATOSIS | SERUM FERRITIN | T2MRI | BETA-THALASSEMIA MAJOR | T2-ASTERISK-CARDIOVASCULAR MAGNETIC-RESONANCE | SICKLE-CELL-DISEASE | IDIOPATHIC HEMOCHROMATOSIS | ENDOMYOCARDIAL BIOPSY | Cardiomyopathies - blood | Echocardiography | Humans | Myocardium - pathology | Tomography, X-Ray Computed | Biomarkers - blood | Cardiomyopathies - etiology | Critical Pathways | Cardiomyopathies - therapy | Iron Overload - blood | Magnetic Resonance Imaging | Iron Overload - complications | Iron - physiology | Biopsy | Iron Overload - therapy | Cardiomyopathies - diagnosis | Iron Overload - diagnosis | Heart failure | Free radicals | Liver diseases | Transplants & implants | Ischemia | Cardiomyopathy | Rodents | Mortality | Homeostasis | Mutation | Sickle cell disease | Blood | Iron overload cardiomyopathy
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11. Communication in universities: a(an) (un)restrained professional model
by Granget, Lucia
Communication et organisation, ISSN 1168-5549, 01/2012, Volume 41, pp. 181 - 194
// ABSTRACT IN ENGLISH: This article attempts to capture and characterize the competency model of framing communication in universities. This model is... 
Overload
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12. Full Text Liver Iron, HFE Gene Mutations, and Hepatocellular Carcinoma Occurrence in Patients With Cirrhosis
by Nahon, Pierre and Sutton, Angela and Rufat, Pierre and Ziol, Marianne and Thabut, Gabriel and Schischmanoff, Pierre–Olivier and Vidaud, Dominique and Charnaux, Nathalie and Couvert, Philippe and Ganne–Carrie, Nathalie and Trinchet, Jean–Claude and Gattegno, Liliane and Beaugrand, Michel
Gastroenterology, ISSN 0016-5085, 2008, Volume 134, Issue 1, pp. 102 - 110
Background & Aims: The influence of HFE gene mutations and liver iron overload on hepatocellular carcinoma (HCC) occurrence in patients with cirrhosis is... 
Gastroenterology and Hepatology | SURVIVAL | OVERLOAD | DISEASES | CHRONIC HEPATITIS-C | ALCOHOLIC CIRRHOSIS | HEMOCHROMATOSIS GENE | DEATH | ACCUMULATION | PREVALENCE | GASTROENTEROLOGY & HEPATOLOGY | Hepatitis C - metabolism | Hemochromatosis Protein | Humans | Middle Aged | Male | Liver Neoplasms - etiology | Iron Overload - metabolism | Adult | Female | Hepatitis C - complications | Carcinoma, Hepatocellular - etiology | Liver Cirrhosis, Alcoholic - complications | Iron Overload - genetics | Membrane Proteins - genetics | Liver - metabolism | Hepatitis C - genetics | Histocompatibility Antigens Class I - genetics | Mutation - genetics | Iron Overload - complications | Liver Cirrhosis, Alcoholic - genetics | Liver Neoplasms - metabolism | Aged | Liver Cirrhosis, Alcoholic - metabolism | Carcinoma, Hepatocellular - metabolism | Cohort Studies | Care and treatment | Gene mutations | Analysis | Liver | Genetic aspects | Iron | Hepatoma | Liver cirrhosis | Risk factors | Cancer | Histocompatibility Antigens Class I | Liver Neoplasms | Liver Cirrhosis, Alcoholic | Membrane Proteins | Life Sciences | Santé publique et épidémiologie | Mutation | Carcinoma, Hepatocellular | Hepatitis C | Iron Overload
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13. Full Text Severe cardiac iron toxicity in two adults with sickle cell disease
by Oduor, Hellen and Minniti, Caterina P and Brofferio, Alessandra and Gharib, Ahmed M and Abd‐Elmoniem, Khaled Z and Hsieh, Matthew M and Tisdale, John F and Fitzhugh, Courtney D
Transfusion, ISSN 0041-1132, 03/2017, Volume 57, Issue 3, pp. 700 - 704
BACKGROUND Use of chronic blood transfusions as a treatment modality in patients with blood disorders places them at risk for iron overload. Since patients... 
OVERLOAD | MORTALITY | MORBIDITY | TRANSFUSED PATIENTS | MAGNETIC-RESONANCE | BETA-THALASSEMIA | HEMATOLOGY | Anemia, Sickle Cell - physiopathology | Arrhythmias, Cardiac - therapy | Anemia, Sickle Cell - complications | Humans | Male | Arrhythmias, Cardiac - etiology | Iron Overload - physiopathology | Arrhythmias, Cardiac - physiopathology | Iron Overload - blood | Iron Overload - etiology | Anemia, Sickle Cell - therapy | Ferritins - blood | Iron Overload - therapy | Adult | Female | Arrhythmias, Cardiac - blood | Anemia, Sickle Cell - blood | Iron - blood | Heart | Sickle cell anemia | Mortality | Cardiac patients | Ferritin | Disease susceptibility | Diagnostic imaging | Blood transfusion | Index Medicus | cardiac iron overload | iron chelation | blood transfusion | sickle cell disease
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14. Full Text Improved survival of thalassaemia major in the UK and relation to T2 cardiovascular magnetic resonance
by Modell, Bernadette and Khan, Maren and Darlison, Matthew and Westwood, Mark A and Ingram, David and Pennell, Dudley J
Journal of Cardiovascular Magnetic Resonance, ISSN 1097-6647, 2008, Volume 10, Issue 1, pp. 42 - 42
Background: The UK Thalassaemia Register records births, deaths and selected clinical data of patients with thalassaemia who are resident in the UK. A study of... 
CARDIAC & CARDIOVASCULAR SYSTEMS | DEFEROXAMINE | TRANSFUSIONAL IRON OVERLOAD | TRANSFERABILITY | CARDIOMYOPATHY | MYOCARDIAL IRON | DESFERRIOXAMINE | BETA-THALASSEMIA | DEFERIPRONE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | COMBINED THERAPY | CHELATION | beta-Thalassemia - pathology | Anemia - mortality | Iron Overload - mortality | Humans | Middle Aged | Child, Preschool | Male | beta-Thalassemia - complications | Iron Overload - pathology | beta-Thalassemia - mortality | Cardiomyopathies - etiology | Cause of Death | Iron Overload - etiology | Young Adult | Time Factors | Cardiomyopathies - mortality | Life Expectancy | Adult | Female | Registries | Child | Anemia - etiology | Communicable Diseases - mortality | Iron Chelating Agents - therapeutic use | beta-Thalassemia - therapy | Cardiomyopathies - pathology | Treatment Outcome | United Kingdom | Cardiomyopathies - therapy | Magnetic Resonance Imaging | Bone Marrow Transplantation - mortality | Iron Overload - therapy | Adolescent | Bone Marrow Transplantation - adverse effects | Pyridones - therapeutic use | Communicable Diseases - complications | Usage | Control | Magnetic resonance imaging | Patient outcomes | Physiological aspects | Thalassemia | Iron in the body | Heart diseases | Risk factors
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