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p-jnk (31) 31
index medicus (18) 18
apoptosis (14) 14
animals (10) 10
humans (10) 10
immunohistochemistry (8) 8
male (8) 8
activation (7) 7
cancer (7) 7
jnk mitogen-activated protein kinases - metabolism (7) 7
oncology (7) 7
phosphorylation (7) 7
cell biology (6) 6
expression (6) 6
jnk (6) 6
kinases (6) 6
rats (6) 6
analysis (5) 5
cells (5) 5
map kinase kinase 4 - metabolism (5) 5
mice (5) 5
proteins (5) 5
rats, sprague-dawley (5) 5
c-jun (4) 4
inflammation (4) 4
map kinase (4) 4
neurosciences (4) 4
oxidative stress (4) 4
pharmacology & pharmacy (4) 4
protein-kinase (4) 4
stress (4) 4
apoptosis - drug effects (3) 3
bax (3) 3
biochemistry & molecular biology (3) 3
biochemistry, general (3) 3
breast cancer (3) 3
care and treatment (3) 3
cell cycle (3) 3
death (3) 3
disease models, animal (3) 3
female (3) 3
gene expression regulation - drug effects (3) 3
genetic aspects (3) 3
inhibition (3) 3
ischemia (3) 3
metastasis (3) 3
neurons (3) 3
p-akt (3) 3
p-erk (3) 3
p-p38 (3) 3
pathway (3) 3
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research (3) 3
research paper (3) 3
rodents (3) 3
signal transduction (3) 3
activated protein-kinase (2) 2
acute-renal-failure (2) 2
animal experimentation (2) 2
antioxidants (2) 2
astrocytes (2) 2
astrocytes - drug effects (2) 2
basal-like phenotype (2) 2
binding (2) 2
calcium (2) 2
cancer research (2) 2
carcinoma (2) 2
cardiology (2) 2
caspase-3 (2) 2
cdc42 gtp-binding protein - metabolism (2) 2
cell death (2) 2
cell line, tumor (2) 2
cell-death (2) 2
cellular signal transduction (2) 2
chemistry, medicinal (2) 2
chemotherapy (2) 2
cispaltin (2) 2
cisplatin (2) 2
complications and side effects (2) 2
cytochrome c (2) 2
cytokines (2) 2
diabetes (2) 2
diabetes mellitus, experimental - drug therapy (2) 2
diabetes mellitus, experimental - metabolism (2) 2
diabetes mellitus, experimental - pathology (2) 2
dicoumarol (2) 2
disease progression (2) 2
endoribonuclease 1 (2) 2
enzyme activation - drug effects (2) 2
enzymes (2) 2
extracellular signal-regulated kinase (2) 2
fas-l (2) 2
gene expression (2) 2
genipin (2) 2
glucose-regulated protein-78 (2) 2
health aspects (2) 2
hyperglycemia (2) 2
induced apoptosis (2) 2
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jnk mitogen-activated protein kinases (2) 2
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1. Full Text The Role of Phospho-c-Jun N-Terminal Kinase Expression on hepatocyte Necrosis and Autophagy in the Cholestatic Liver
by Kwak, Bong Jun and Choi, Ho Joong and Kim, Kee-Hwan and Kim, Say-June and Kim, Ok-Hee and You, Young Kyoung and Lee, Tae Yoon and Ahn, Joseph
Journal of Surgical Research, ISSN 0022-4804, 09/2019, Volume 241, pp. 254 - 263
Clinically, liver fibrosis and cholestasis are two major disease entities, ultimately leading to hepatic failure. Although autophagy plays a substantial role... 
Liver fibrosis | Cholestatic liver disease | p-JNK | Autophagy | Necrosis | PATHWAYS | SIGNAL | SURGERY | APOPTOSIS | REACTIVE OXYGEN | Immunohistochemistry | Liver diseases | Cell death | Analysis | Liver
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2. Huaier aqueous extract inhibits cervical cancer cell proliferation via JNK/p38 pathway
by Yan, Li and Liu, Xiaolin and Yin, Aijun and Wei, Yuyan and Yang, Qifeng and Kong, Beihua
International Journal of Oncology, ISSN 1019-6439, 09/2015, Volume 47, Issue 3, pp. 1054 - 1060
Although the anticancer effects of Huaier extract have been widely investigated, including anti-proliferate, anti-angiogenic and anti-metastatic activities,... 
Huaier | Proliferation | P-JNK | Cervical cancer | Cell cycle | INACTIVATION | APOPTOSIS | proliferation | ONCOLOGY | cell cycle | p-JNK | JNK | KINASE | cervical cancer
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3. Anti-Melanogenic Effects of Hydroxyectoine via MITF Inhibition by JNK, p38, and AKT Pathways in B16F10 Melanoma Cells
by Chung, YC and Kim, MJ and Kang, EY and Kim, YB and Kim, BS and Park, SM and Hyun, CG
NATURAL PRODUCT COMMUNICATIONS, ISSN 1934-578X, 06/2019, Volume 14, Issue 6
Melanin plays a role in determining human skin color of a person, and a large amount of melanin makes the skin color look darkened. The proper amount of... 
ECTOINE | CHEMISTRY, MEDICINAL | PROTEIN | ACID | melanin | FOOD SCIENCE & TECHNOLOGY | INVOLVEMENT | melanogenesis | MITF | hydroxyectoine | tyrosinase | whitening | TRP-1 | B16F10 melanoma cell | p-AKT | p-JNK | p-p38 | SKIN | PIGMENTATION
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4. Full Text Zbtb7c is a molecular ‘off’ and ‘on’ switch of Mmp gene transcription
by Jeon, Bu-Nam and Yoon, Jae-Hyeon and Kim, Kyung-Sup and Kim, Kunhong and Kim, Min-Kyeong and Choi, Won-Il and Koh, Dong-In and Hur, Man-Wook and Hur, Benjamin
BBA - Gene Regulatory Mechanisms, ISSN 1874-9399, 11/2016, Volume 1859, Issue 11, pp. 1429 - 1439
Matrix metalloproteinases (MMPs) are zinc-containing endopeptidases that play roles in cell proliferation, migration, differentiation, angiogenesis, and... 
c-Jun | Zbtb7c (Kr-pok) | NCoR | p-Jnk | Mmps | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | FAMILY | PATHOGENESIS | MATRIX METALLOPROTEINASES | REPRESSES | BIOPHYSICS | EXTRACELLULAR-MATRIX | MICE | EXPRESSION | BINDING | Ubiquitin | Genetic aspects | Genetic transcription | Genes | Protein binding
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5. Full Text Rosmarinic acid modulates the antioxidant status and protects pancreatic tissues from glucolipotoxicity mediated oxidative stress in high-fat diet: streptozotocin-induced diabetic rats
by Govindaraj, Jayanthy and Sorimuthu Pillai, Subramanian
Molecular and Cellular Biochemistry, ISSN 0300-8177, 6/2015, Volume 404, Issue 1, pp. 143 - 159
Persistent hyperglycemia and elevated levels of free fatty acids (FFA) contribute to oxidative stress, a proximate cause for the onset and progression of... 
Life Sciences | Biochemistry, general | NF-κB | Cytokines | p-JNK | Nrf-2 | P38 MAPK | Medical Biochemistry | Oncology | Rosmarinic acid | Cardiology | ACTIVATION | ASSAY | MECHANISM | INVOLVEMENT | CROSS-LINKING | CELL BIOLOGY | NF-kappa B | BETA-CELL DYSFUNCTION | GLUCOSE TOXICITY | NF-KAPPA-B | GLYCATION END-PRODUCTS | EXTRACT | Diabetes Mellitus, Experimental - drug therapy | Cinnamates - administration & dosage | Glycated Hemoglobin A - metabolism | Humans | Pancreas - drug effects | Rats | Blood Glucose | Depsides - administration & dosage | Pancreas - metabolism | Insulin - blood | Animals | Insulin-Secreting Cells - drug effects | Diet, High-Fat | Antioxidants - administration & dosage | Insulin Resistance - genetics | Diabetes Mellitus, Experimental - pathology | Glycation End Products, Advanced - blood | Insulin-Secreting Cells - pathology | Oxidative Stress - drug effects | Diabetes Mellitus, Experimental - metabolism | Antioxidants | Complications and side effects | Oxidative stress | Hyperglycemia | Pancreatic beta cells | Diet | Streptozocin | Blood sugar | Glutathione transferase | Superoxide | Fatty acids | Tissue | Acids | Toxicity | Pancreatic cancer | Rodents | Oils & fats | Diabetes | Drug therapy
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6. Full Text Protective role and mechanism of snakegourd peel against myocardial infarction in rats
by Yang, Ming and Yang, Guanlin and Min, Dongyu and Yan, Junwei and Lin, Guijun
Phytomedicine, ISSN 0944-7113, 03/2018, Volume 42, pp. 18 - 24
Injection of snakegourd peel (SP), an herb used in traditional Chinese medicine, is used to treat coronary artery disease and stable angina in China. However,... 
Myocardial infarction | p-p38MAPK | Snakegourd peel | p-JNK | Apoptosis | CHEMISTRY, MEDICINAL | ACTIVATED PROTEIN-KINASE | INDUCED APOPTOSIS | JNK | MURINE MACROPHAGES | P38 MAPK | MAP KINASES | VENTRICULAR MYOCYTES | ARSENIC TRIOXIDE | PLANT SCIENCES | CARDIOMYOCYTE APOPTOSIS | INTEGRATIVE & COMPLEMENTARY MEDICINE | CALCIUM | PHARMACOLOGY & PHARMACY
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7. Full Text Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling
by Xiao, Bin and Chen, Daxiang and Luo, Shuhong and Hao, Wenbo and Jing, Fangyan and Liu, Tiancai and Wang, Suihai and Geng, Yan and Li, Linhai and Xu, Weiwen and Zhang, Yajie and Liao, Xiaoqing and Zuo, Daming and Wu, Yingsong and Li, Ming and Ma, Qiang
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 31, pp. 50057 - 50073
The translationally controlled tumor protein (TCTP) can be secreted independently of the endoplasmic reticulum/Golgi pathway and has extrinsic activities when... 
Metastasis | P-JNK | Extracellular TCTP | Cdc42 | CELLS | extracellular TCTP | MESENCHYMAL TRANSITION | ANTIAPOPTOTIC ACTIVITY | TCTP | HYPOXIA | CELL BIOLOGY | HISTAMINE-RELEASING FACTOR | metastasis | p-JNK | PATHWAY | EXPRESSION | PROGRESSION | Humans | Middle Aged | Male | cdc42 GTP-Binding Protein - metabolism | Matrix Metalloproteinase 9 - metabolism | Neoplasm Metastasis | MAP Kinase Kinase 4 - metabolism | Biomarkers, Tumor - metabolism | Female | Colorectal Neoplasms - metabolism | Recombinant Proteins - metabolism | Signal Transduction | Neoplasm Invasiveness | Liver - metabolism | Gene Silencing | Inflammation | Disease Progression | Animals | Mice, Nude | Cell Line, Tumor | Hypoxia | Aged | Mice | Mice, Inbred BALB C | Cell Movement
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8. Full Text Ambroxol attenuates cisplatin-induced hepatotoxicity and nephrotoxicity via inhibition of p-JNK/p-ERK
by Sallam, Nada and Kenawy, Sanaa A and Awad, Azza S and Bishr, Abeer and Nour El-Din, Mahmoud
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 2019, Volume 97, Issue 1, pp. 55 - 64
Hepatotoxicity and nephrotoxicity are important drawbacks of cisplatin. The objective of this study is to evaluate the ability of ambroxol in 2 different doses... 
néphrotoxicité | hépatotoxicité | nephrotoxicity | p-JNK | cisplatine | hepatotoxicity | cisplatin | ambroxol | p-ERK | Ambroxol | Hepatotoxicity | Nephrotoxicity | P-ERK | P-JNK | Cisplatin | APOPTOSIS | OXIDATIVE STRESS | PHYSIOLOGY | INJURY | N-ACETYLCYSTEINE | OLEUROPEIN | DAMAGE | INFLAMMATION | LIVER | PHARMACOLOGY & PHARMACY | MICE | MOLECULAR-MECHANISMS | Prevention | Complications and side effects | Liver diseases | Expectorants | Patient outcomes | Dosage and administration | Kidney diseases | Oxidative stress | Transcription factors | Liver | Interleukin | Acetylcysteine | Superoxide dismutase | Kinases | Caspase-3 | Liver cancer | Elevation | Glutathione reductase | Physiology | Inhibition | Damage | Glutathione | Creatinine | Enzymes | Alanine | Kidneys | Extracellular signal-regulated kinase | c-Jun protein | Caspase | Superoxide | Inflammation | Pharmacology | Tumor necrosis factor-α | Nitrogen | Patients | Malondialdehyde | Urea | Alanine transaminase | Biomarkers | Aspartate aminotransferase | Apoptosis | Cancer | Reductase | Index Medicus
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9. Full Text Spinal astrocytic c-Jun N-terminal kinase (JNK) activation as counteracting mechanism to the amitriptyline analgesic efficacy in painful peripheral neuropathies
by Sanna, Maria Domenica and Ghelardini, Carla and Galeotti, Nicoletta
European Journal of Pharmacology, ISSN 0014-2999, 03/2017, Volume 798, pp. 85 - 93
Several drugs and agents are currently used for the treatment of neuropathic pain. Among them amitriptyline, a tricyclic antidepressant drug, represent a first... 
Amitriptyline | p-JNK | Astrocytes | Neuropathic pain | CORD | PROTEIN-KINASE | ANTIDEPRESSANTS | NEURONS | PHARMACOLOGY & PHARMACY | SIGNAL-REGULATED KINASE | NERVE LIGATION | CONTRIBUTES | EXPRESSION | ERK | HYPERSENSITIVITY | Peripheral Nerve Injuries - complications | Analgesics - pharmacology | Analgesics - therapeutic use | Astrocytes - drug effects | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Hyperalgesia - complications | Neuralgia - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | Male | Astrocytes - enzymology | Neuralgia - pathology | Enzyme Activation - drug effects | Glial Fibrillary Acidic Protein - metabolism | Neuralgia - drug therapy | Gene Expression Regulation - drug effects | Animals | Biocatalysis - drug effects | Spinal Cord - pathology | Neuralgia - etiology | Amitriptyline - therapeutic use | Mice | Protein Kinase Inhibitors - pharmacology | Amitriptyline - pharmacology | Animal experimentation | Highly active antiretroviral therapy | Antiviral agents | Polyneuropathies | Analgesics | Antidepressants | Analysis | Intermediate filament proteins | Care and treatment | Pain | Index Medicus
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10. Full Text Endoplasmic reticulum stress-induced neuronal inflammatory response and apoptosis likely plays a key role in the development of diabetic encephalopathy
by Wang, Zhouguang and Huang, Yan and Cheng, Yi and Tan, Yi and Wu, Fenzan and Wu, Jiamin and Shi, Hongxue and Zhang, Hongyu and Yu, Xichong and Gao, Hongchang and Lin, Li and Cai, Jun and Zhang, Jinsan and Li, Xiaokun and Cai, Lu and Xiao, Jian
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 48, pp. 78455 - 78472
We assumed that diabetic encephalopathy (DEP) may be induced by endoplasmic reticulum (ER)-mediated inflammation and apoptosis in central nervous system. To... 
ER stress | Inflammation | Diabetes | p-JNK | Apoptosis | OXIDATIVE STRESS | ACTIVATION | RAT | MEMORY IMPAIRMENT | apoptosis | C-KIT | BETA-CELL FUNCTION | CELL BIOLOGY | COGNITIVE DYSFUNCTION | HIPPOCAMPUS | INHIBITION | HYPERGLYCEMIA | inflammation | diabetes | Tumor Necrosis Factor-alpha - metabolism | Brain Diseases - metabolism | Neurons - pathology | Diabetes Mellitus, Experimental - drug therapy | Phosphorylation | Apoptosis - drug effects | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Cognition | Diabetes Mellitus, Type 2 - metabolism | Hippocampus - drug effects | Behavior, Animal | Dose-Response Relationship, Drug | Transfection | Time Factors | Diabetes Mellitus, Experimental - complications | Neurons - metabolism | Brain Diseases - etiology | JNK Mitogen-Activated Protein Kinases - genetics | Diabetes Mellitus, Experimental - metabolism | Neurons - drug effects | Interleukin-6 - metabolism | Diabetes Mellitus, Type 2 - complications | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Endoplasmic Reticulum Stress - drug effects | Signal Transduction | Anti-Inflammatory Agents - pharmacology | Heat-Shock Proteins - metabolism | Cells, Cultured | Hippocampus - pathology | Rats, Sprague-Dawley | Hippocampus - metabolism | Activating Transcription Factor 6 - metabolism | Animals | Brain Diseases - pathology | Brain Diseases - prevention & control | X-Box Binding Protein 1 - metabolism | Diabetes Mellitus, Experimental - pathology | Protein Kinase Inhibitors - pharmacology | Diabetes Mellitus, Type 2 - pathology | Diabetes Mellitus, Type 2 - drug therapy | Transcription Factor CHOP - metabolism
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11. Full Text Evaluation of the p‐AKT, p‐JNK and FoxO3a function in oral epithelial dysplasia
by Chaves, FN and Bezerra, TMM and Barros Silva, PG and Oliveira, FAF and Sousa, FB and Costa, FWG and Alves, APNN and Pereira, KMA
Oral Diseases, ISSN 1354-523X, 04/2017, Volume 23, Issue 3, pp. 367 - 378
Objectives To evaluate the expression of p‐AKT, p‐JNK, FoxO3a, and Ki‐67 in samples of oral squamous cell carcinoma (OSCC) and oral epithelial dysplasias... 
oral epithelial dysplasia | p‐JNK | FoxO3a | oral squamous cell carcinoma | immunohistochemistry | p‐AKT | p-AKT | p-JNK | PROTEIN-KINASE B/AKT | CONSTITUTIVE ACTIVATION | N-TERMINAL KINASE | KAPPA-B | ONCOGENIC TRANSFORMATION | BREAST-CANCER | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | MALIGNANT-TRANSFORMATION | DENTISTRY, ORAL SURGERY & MEDICINE | SQUAMOUS-CELL CARCINOMA | PLECKSTRIN HOMOLOGY DOMAIN | Phosphorylation | Cross-Sectional Studies | Humans | Carcinoma, Squamous Cell - chemistry | JNK Mitogen-Activated Protein Kinases - metabolism | Forkhead Box Protein O3 - analysis | Mouth Neoplasms - chemistry | JNK Mitogen-Activated Protein Kinases - analysis | Mouth Mucosa - chemistry | Ki-67 Antigen - analysis | Proto-Oncogene Proteins c-akt - analysis | Mouth Mucosa - pathology | Proto-Oncogene Proteins c-akt - metabolism | Immunohistochemistry | Dysplasia | Squamous cell carcinoma | Analysis | Oral cancer
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12. Full Text Apoptosis induced by genipin in human leukemia K562 cells: Involvement of c-Jun N-terminal kinase in G2/M arrest
by Feng, Qian and Cao, Hou-Li and Xu, Wei and Li, Xiao-Rong and Ren, Yan-Qin and Du, Lin-Fang
Acta Pharmacologica Sinica, ISSN 1671-4083, 04/2011, Volume 32, Issue 4, pp. 519 - 527
To investigate the effect of genipin on apoptosis in human leukemia K562 cells in vitro and elucidate the underlying mechanisms. The effect of genipin on K562... 
K562 cells | cell cycle | p-JNK | genipin | Bax | apoptosis | dicoumarol | cytochrome c | p63 | Fas-L | Iridoids | Leukemia - pathology | Apoptosis - drug effects | Cell Division | Humans | Iridoid Glycosides - pharmacology | K562 Cells | G2 Phase | JNK Mitogen-Activated Protein Kinases - metabolism | Original
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13. Full Text Elevated expression of phosphorylated c-Jun NH2-terminal kinase in basal-like and “triple-negative” breast cancers
by Wang, Xiao, MD, PHD and Chao, Lan, MD, PHD and Li, Xin, MD and Ma, Guohui, MD and Chen, Liansheng, MD and Zang, Yixiu, MD and Zhou, Gengyin, MD
Human Pathology, ISSN 0046-8177, 2010, Volume 41, Issue 3, pp. 401 - 406
Summary Basal-like carcinomas and human epidermal growth factor receptor 2 (HER-2/neu) overexpression carcinomas are the subgroups of breast cancers that have... 
Pathology | Breast cancer | Basal-like phenotype | p-JNK | “Triple-negative” phenotype
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14. Anticancer activity of Luteolin and its synergism effect with BCG on human bladder cancer cell line BIU-87
by Yang, Guantian and Wang, Zengjun and Wang, Wei and Zhou, Xiang and Hu, Xiangnong and Yang, Jianjun
Journal of Central South University (Medical Sciences), ISSN 1672-7347, 2014, Volume 39, Issue 4, pp. 371 - 378
P-JNK | BCG | Human bladder cancer cell line | Luteolin | Caspase-3 | Apoptosis | Drug synergism
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15. Full Text Propranolol as a potentially novel treatment of arteriovenous malformations
by Lu, Jianyun and Anvari, Radean and Wang, Jinwei and Huang, Jinhua and Huang, Jian and Pei, Shiyao and Xiang, Yaping and Yin, Zhaoqi and Chen, Jing and Nelson, J. Stuart and Tan, Wenbin
JAAD Case Reports, ISSN 2352-5126, 05/2018, Volume 4, Issue 4, pp. 355 - 358
arteriovenous malformation | MAPK | propranolol
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16. Full Text Overexpression of macrophage migration inhibitory factor in adenoid cystic carcinoma: correlation with enhanced metastatic potential
by Liu, Hui and Liu, Hui and Chen, Gang and Chen, Gang and Zhang, Wei and Zhang, Wei and Zhu, Jun-Yi and Zhu, Jun-Yi and Lin, Zhao-Quan and Lin, Zhao-Quan and Gong, Zhong-Cheng and Gong, Zhong-Cheng and Wang, Feng-Qin and Wang, Feng-Qin and Jia, Jun and Jia, Jun and Sun, Zhi-Jun and Sun, Zhi-Jun and Zhao, Yi-Fang and Zhao, Yi-Fang
Journal of Cancer Research and Clinical Oncology, ISSN 0171-5216, 2/2013, Volume 139, Issue 2, pp. 287 - 295
Adenoid cystic carcinoma (ACC) is a malignant tumor frequently arising in salivary glands with poor long-term prognosis due to high rates of local recurrences... 
ISO-1 | Medicine & Public Health | Hematology | p-JNK | Oncology | Cancer Research | Internal Medicine | Metastasis | MIF | Adenoid cystic carcinoma | MAMMALIAN TARGET | RAPAMYCIN | HYPOXIA-INDUCIBLE FACTOR | ANGIOGENESIS | ISOLIQUIRITIGENIN | ADENOCARCINOMA | FACTOR MIF | CHEMOTHERAPY | INVASION | ONCOLOGY | ASSOCIATION | Gene Expression | Carcinoma, Adenoid Cystic - pathology | Salivary Gland Neoplasms - genetics | Carcinoma, Adenoid Cystic - metabolism | Humans | Macrophage Migration-Inhibitory Factors - metabolism | Enzyme Activation - drug effects | Isoxazoles - pharmacology | Neoplasm Metastasis | MAP Kinase Kinase 4 - metabolism | Macrophage Migration-Inhibitory Factors - genetics | Carcinoma, Adenoid Cystic - genetics | Salivary Gland Neoplasms - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Enzyme Activation - genetics | Salivary Gland Neoplasms - pathology | Carcinoma | Macrophages | Tumor proteins | Analysis | Cancer
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17. Full Text Apoptosis induced by genipin in human leukemia K562 cells： involvement of c-Jun N-terminal kinase in G~M arrest
by Qian FENG Hou-li CAO Wei XU Xiao-rong LI Yan-qin REN Lin-fang DU
中国药理学报：英文版, ISSN 1671-4083, 2011, Volume 32, Issue 4, pp. 519 - 527
Aim： To investigate the effect of genipin on apoptosis in human leukemia K562 cells in vitro and elucidate the underlying mechanisms. Methods： The effect of... 
细胞凋亡 | K562细胞 | M期 | Fas配体 | 激酶 | 诱导形成 | Bax蛋白 | 白血病 | ACTIVATION | cell cycle | genipin | JNK | apoptosis | dicoumarol | DEATH | p63 | CANCER | CHEMISTRY, MULTIDISCIPLINARY | PROTEIN-KINASES | K562 cells | p-JNK | PATHWAY | Bax | NITRIC-OXIDE | GENIPOSIDE | GARDENIA | PHARMACOLOGY & PHARMACY | cytochrome c | Fas-L
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18. Full Text The effects of MOTILIPERM on cisplatin induced testicular toxicity in Sprague-Dawley rats
by Soni, Kiran Kumar and Zhang, Li Tao and You, Jae Hyung and Lee, Sung Won and Kim, Chul Young and Cui, Wan Shou and Chae, Han Jung and Kim, Hye Kyung and Park, Jong Kwan
Cancer Cell International, ISSN 1475-2867, 12/2015, Volume 15, Issue 1, p. 121
Background: Cisplatin causes male infertility but the exact mechanism have not been clarified, yet. MOTILIPERM has been implicated in alleviation of... 
Glucose-regulated protein-78 (GRP-78) | Phosphorylated inositol-requiring transmembrane kinase/endoribonuclease 1 (IRE1) | Phosphorylated c-jun-N-terminal kinase (p-JNK) | Spermatogenic cell denity | Cispaltin (CIS) | Steroidogenic acute regulatory (StAR) protein | MOTILIPERM | SPERMATOGENESIS | CIS-DIAMMINEDICHLOROPLATINUM | TESTOSTERONE | PROTEIN-KINASE | CELL-DEATH | ONCOLOGY | TESTIS | ENDOPLASMIC-RETICULUM | STRESS | EXPRESSION
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