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Nature, ISSN 0028-0836, 09/2016, Volume 538, Issue 7623, pp. 118 - 122
Journal Article
Journal Article
Science, ISSN 0036-8075, 5/2011, Volume 332, Issue 6032, pp. 963 - 966
Transcriptionally silent genes can be marked by histone modifications and regulatory proteins that indicate the genes' potential to be activated. Such marks... 
Chromatin | Liver | REPORTS | Stem cells | Multipotent stem cells | Embryonic cells | Pancreas | Embryonic stem cells | Pluripotent stem cells | Embryos | Endoderm | TRANSCRIPTION FACTORS | STEM-CELLS | IN-VITRO | GENE | MULTIDISCIPLINARY SCIENCES | DISTINCT | ENDODERM | DIFFERENTIATION | PROMOTER | EXPRESSION | ACETYLTRANSFERASE | Chromatin - metabolism | p300-CBP Transcription Factors - antagonists & inhibitors | Homeodomain Proteins - metabolism | Multipotent Stem Cells - metabolism | Pancreas - cytology | Liver - embryology | Bone Morphogenetic Proteins - metabolism | Hepatocytes - cytology | Chromatin Immunoprecipitation | p300-CBP Transcription Factors - genetics | Endoderm - cytology | Gene Expression Regulation, Developmental | Trans-Activators - genetics | Cell Differentiation | Acetylation | Cell Culture Techniques | Signal Transduction | Cell Separation | Liver - metabolism | Embryonic Induction | Embryonic Development | Pancreas - metabolism | Pancreas - embryology | Enhancer of Zeste Homolog 2 Protein | Homeodomain Proteins - genetics | Transcription Factors - metabolism | p300-CBP Transcription Factors - metabolism | Polycomb Repressive Complex 2 | Animals | Histone-Lysine N-Methyltransferase - metabolism | Multipotent Stem Cells - cytology | Regulatory Elements, Transcriptional | Trans-Activators - metabolism | Liver - cytology | Mice | Protein Processing, Post-Translational | Histones - metabolism | Histones | Physiological aspects | Proteins | Cellular biology | Developmental biology | Rodents | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 12/2015, Volume 75, Issue 23, pp. 5106 - 5119
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2012, Volume 287, Issue 41, pp. 34372 - 34385
Inducible gene expression underlies the epigenetically inherited differentiation program of most immune cells. We report that the promoter of the FOXP3 gene... 
RESPONSE ELEMENT | INTESTINAL INFLAMMATION | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION FACTOR FOXP3 | TRANSFORMING GROWTH-FACTOR-BETA-1 | IN-VIVO | REGULATORY T-CELLS | HISTONE ACETYLTRANSFERASE | BINDING PROTEIN | EXPRESSION | Forkhead Transcription Factors - immunology | T-Lymphocytes, Regulatory - metabolism | p300-CBP Transcription Factors - immunology | Polycomb Repressive Complex 2 - genetics | p300-CBP Transcription Factors - antagonists & inhibitors | Early Growth Response Transcription Factors - biosynthesis | Male | Polycomb-Group Proteins - metabolism | T-Lymphocytes, Regulatory - immunology | p300-CBP Transcription Factors - genetics | Early Growth Response Transcription Factors - genetics | Polycomb Repressive Complex 2 - immunology | T-Lymphocytes, Regulatory - cytology | Response Elements - physiology | Forkhead Transcription Factors - biosynthesis | Kruppel-Like Transcription Factors - biosynthesis | Polycomb-Group Proteins - immunology | Early Growth Response Transcription Factors - immunology | Forkhead Transcription Factors - genetics | Enhancer of Zeste Homolog 2 Protein | Mice, Knockout | p300-CBP Transcription Factors - metabolism | Animals | Polycomb-Group Proteins - genetics | Mice | Polycomb Repressive Complex 2 - metabolism | Gene Silencing - physiology | Kruppel-Like Transcription Factors - genetics | Kruppel-Like Transcription Factors - immunology | Chromatin Assembly and Disassembly - physiology | Index Medicus | DNA and Chromosomes | Histone Modification | Epigenetics | Polycomb | T Cell Biology | FOXP3 | Kruppel-like Factor (KLF) | T Regulatory Cell
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 2015, Volume 308, Issue 9, pp. L962 - L972
Asthma is characterized by airway inflammation and remodeling and CXCL8 is a CXC chemokine that drives steroid-resistant neutrophilic airway inflammation. We... 
Histone acetylation | CXCl8 | Bromodomain | BET protein | Airway smooth muscle | Asthma | SELECTIVE-INHIBITION | CELLS | METHYLATION | PHYSIOLOGY | HEART-FAILURE | airway smooth muscle | C-MYC | PATTERNS | asthma | IL-8 | bromodomain | RESPIRATORY SYSTEM | BROMODOMAIN INHIBITION | GROWTH-FACTOR | EXPRESSION | histone acetylation | Interleukin-8 - genetics | Asthma - metabolism | Humans | RNA Polymerase II - metabolism | Airway Remodeling - immunology | DNA-Binding Proteins - metabolism | DNA Methylation | Transcription, Genetic | Acetylation | Interleukin-8 - metabolism | Myocytes, Smooth Muscle - metabolism | RNA-Binding Proteins - antagonists & inhibitors | Nerve Tissue Proteins - antagonists & inhibitors | Promoter Regions, Genetic | Cells, Cultured | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Inflammation - immunology | Interleukin-8 - antagonists & inhibitors | Muscle, Smooth - metabolism | CCAAT-Enhancer-Binding Protein-beta - metabolism | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | p300-CBP Transcription Factors - metabolism | Transcription Factor RelA - metabolism | Nuclear Proteins - antagonists & inhibitors | Protein Binding | Histones - metabolism | Primary Cell Culture | RNA-Binding Proteins - metabolism | Physiological aspects | Smooth muscle | Development and progression | Genetic aspects | Research | Chemokine receptors | Chromatin | Transcription factors | Chemokines | Cells | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, pp. e65718 - e65718
The morphogenic Hedgehog (Hh) signaling regulates postnatal cerebellar development and its aberrant activation leads to medulloblastoma. The transcription... 
SIGNAL | STEM-CELLS | CANCER | MULTIDISCIPLINARY SCIENCES | HISTONE DEACETYLASE | Chromatin - metabolism | NIH 3T3 Cells | Humans | Zinc Finger Protein Gli2 | Hedgehog Proteins - metabolism | Cerebellum - enzymology | Hedgehog Proteins - genetics | p300-CBP Transcription Factors - genetics | Gene Expression Regulation, Developmental | Kruppel-Like Transcription Factors - metabolism | HEK293 Cells | Transcription, Genetic | Lysine - metabolism | Acetylation | Nuclear Proteins - genetics | Binding Sites | Immune Sera - pharmacology | Promoter Regions, Genetic | Signal Transduction | Nuclear Proteins - metabolism | Transcription Factors - genetics | Transcription Factors - metabolism | p300-CBP Transcription Factors - metabolism | Animals | Nuclear Proteins - antagonists & inhibitors | Cerebellum - cytology | Protein Binding | Cerebellum - growth & development | Mice | Zinc Finger Protein GLI1 | Mutation | Kruppel-Like Transcription Factors - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | Ubiquitin | Chromatin | Lysine | Histones | Genetic aspects | DNA binding proteins | Genetic transcription | Acetates | Cerebellum | Phosphorylation | Transcription factors | Event-related potentials | Activation | Antisera | Kinases | Proteins | Signal transduction | Ubiquitination | Cell cycle | Tumorigenesis | Outerwear | Gene expression | Histone acetyltransferase | Medicine | Signaling | Mutagenesis | Hedgehog protein | Medulloblastoma | Stem cells | Aberration | Cancer | Index Medicus
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2017, Volume 60, Issue 24, pp. 10151 - 10171
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2006, Volume 103, Issue 17, pp. 6653 - 6658
The mechanisms regulating activation of monocytes remain incompletely understood. Herein we provide evidence that Kruppel-like factor 2 (KLF2) inhibits... 
COS cells | T lymphocytes | Edema | Monocytes | Transcriptional regulatory elements | Cell lines | Gene expression regulation | Cellular immunity | Mice | Cells | NF-κB | Inflammation | Transcriptional factor | Transcription | Activator protein 1 | transcription | FACTOR EKLF | MULTIDISCIPLINARY SCIENCES | ATHEROSCLEROSIS | NF-kappa B | activator protein 1 | INHIBITION | GENE | inflammation | IN-VIVO | T-CELL QUIESCENCE | BETA-THALASSEMIA | transcriptional factor | NF-KAPPA-B | TRANSCRIPTION FACTOR | Carrageenan - immunology | RNA, Small Interfering - genetics | p300-CBP Transcription Factors | Monocytes - cytology | Transcription Factor AP-1 - genetics | Atherosclerosis - genetics | Humans | Male | Monocytes - metabolism | NF-kappa B - metabolism | Monocytes - immunology | Transcription Factor AP-1 - metabolism | Case-Control Studies | Kruppel-Like Transcription Factors - metabolism | Histone Acetyltransferases - metabolism | Inflammation Mediators - metabolism | Cell Differentiation | Cell Line | Promoter Regions, Genetic | Gene Expression | Atherosclerosis - immunology | Cell Cycle Proteins - metabolism | Mice, SCID | Macrophage Activation | Transcription Factors - metabolism | Animals | NF-kappa B - genetics | Inflammation - prevention & control | In Vitro Techniques | Kruppel-Like Transcription Factors - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | Kruppel-Like Transcription Factors - immunology | Phagocytosis | Physiological aspects | Chemical properties | Genetic transcription | Immunology | Cytokines | Gene expression | Rodents | Inflammatory diseases | Index Medicus | Biological Sciences
Journal Article
Journal Article
Journal Article