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Journal of Neurochemistry, ISSN 0022-3042, 02/2013, Volume 124, Issue 4, pp. 558 - 570
Hyperhomocysteinemia is an independent risk factor for both acute and chronic neurological disorders, but little is known about the underlying mechanisms by... 
homocysteine | neuronal cell death | crosstalk | NMDA | mitogen‐activated protein kinase | p38 mitogen‐activated protein kinase | ERK | p38 mitogen-activated protein kinase | ERK mitogen-activated protein kinase | PRO-INFLAMMATORY CYTOKINES | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | RETINAL GANGLION-CELLS | IN-VITRO | BIDIRECTIONAL CONTROL | SIGNAL-REGULATED KINASE | METHYL-D-ASPARTATE | DIFFERENTIAL ROLES | MAP Kinase Signaling System - physiology | Calcium - metabolism | Embryo, Mammalian | Caspase 3 - metabolism | Receptors, N-Methyl-D-Aspartate - metabolism | Green Fluorescent Proteins - genetics | Homocysteine - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Cerebral Cortex - cytology | Dose-Response Relationship, Drug | Transfection | Homocysteine - pharmacology | Excitatory Amino Acid Agents - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | RNA Interference - physiology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Enzyme Activation - drug effects | Animals | MAP Kinase Signaling System - drug effects | Cell Death - physiology | Methyl aspartate | Biochemistry | Homocysteine | Neurons | Cell death | Protein kinases | Neurochemistry | Neurological disorders | Apoptosis | Index Medicus | ERK MAPK | p38 MAPK
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2011, Volume 71, Issue 3, pp. 498 - 511
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 07/2010, Volume 120, Issue 7, pp. 2457 - 2473
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 08/2011, Volume 49, Issue 8, pp. 1745 - 1752
► The inhibitory effects of fucoidan on LPS-induced pro-inflammatory mediators in BV2 microglia were investigated. ► Fucoidan inhibited production of NO and... 
PGE2 | NF-κB | Fucoidan | Akt | MAPK | PATHWAYS | FOOD SCIENCE & TECHNOLOGY | ANTICOAGULANT | NEUROTOXICITY | ANTITUMOR | PGE | NF-kappa B | DISEASES | POLYSACCHARIDES | NITRIC-OXIDE | TOXICOLOGY | RECEPTORS | EXPRESSION | MOLECULAR-MECHANISMS | Tumor Necrosis Factor-alpha - metabolism | Microglia - metabolism | Plant Extracts - pharmacology | Tumor Necrosis Factor-alpha - genetics | Fucus - chemistry | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Interleukin-1beta - genetics | Lipopolysaccharides - adverse effects | Proto-Oncogene Proteins c-akt - genetics | Cyclooxygenase 2 - genetics | Interleukin-1beta - metabolism | Chemokine CCL2 - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | JNK Mitogen-Activated Protein Kinases - genetics | Proto-Oncogene Proteins c-akt - metabolism | Microglia - cytology | Rabbits | NF-kappa B - antagonists & inhibitors | Microglia - drug effects | Anti-Inflammatory Agents - pharmacology | Nitric Oxide - antagonists & inhibitors | Down-Regulation | Cells, Cultured | p38 Mitogen-Activated Protein Kinases - genetics | Chemokine CCL2 - genetics | Polysaccharides - pharmacology | Dinoprostone - metabolism | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | Cyclooxygenase 2 - metabolism | Mitogen-Activated Protein Kinases - genetics | Mice | Dinoprostone - antagonists & inhibitors | Nitric Oxide - metabolism | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Mitogen-Activated Protein Kinases - metabolism | Nitric Oxide Synthase Type II - metabolism | Index Medicus
Journal Article
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