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Journal Article
2017, ISBN 9782889453399
Mitogen-activated protein kinase (MAPK) pathways are evolutionarily conserved in all eukaryotes and allow cells to respond to changes in the physical and... 
kinase | cell differentiation | p38 | MSK | scaffold | inflammation | JNK | cancer | MAPK | ERK
eBook
Diabetes, ISSN 0012-1797, 02/2014, Volume 63, Issue 2, pp. 514 - 525
The number and activity of brown adipocytes are linked to the ability of mammals to resist body fat accumulation. In some conditions, certain white adipose... 
OBESITY | GENE | ENDOCRINOLOGY & METABOLISM | MUSCLE | RECEPTOR | PROLIFERATION | DIFFERENTIATION | EXPRESSION | FAT-CELL | EXERCISE | ADIPOSE-TISSUE | MAP Kinase Signaling System - physiology | Nitriles - pharmacology | Adipose Tissue, White - metabolism | Caenorhabditis elegans Proteins - metabolism | Adipocytes - cytology | Male | Adipocytes - drug effects | Extracellular Signal-Regulated MAP Kinases - metabolism | Recombinant Proteins | Extracellular Signal-Regulated MAP Kinases - genetics | Pichia - metabolism | Membrane Transport Proteins - genetics | Dietary Fats | Membrane Transport Proteins - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Butadienes - pharmacology | Fibronectins - pharmacology | Fibronectins - administration & dosage | Mice, Inbred C57BL | Rats | p38 Mitogen-Activated Protein Kinases - genetics | Imidazoles - pharmacology | 3T3-L1 Cells | Rats, Sprague-Dawley | Animals | Adipocytes - metabolism | Pichia - genetics | Protein Binding | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Fibronectins - genetics | Mice | Pyridines - pharmacology | Mutation | Mitochondrial Uncoupling Proteins | Caenorhabditis elegans Proteins - genetics | Adipose Tissue, White - drug effects | Physiological research | Cellular signal transduction | Research | Identification and classification | Membrane proteins | Proteins | Homeostasis | Diabetes | Kinases | Genes | Cells | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2007, Volume 401, Issue 2, pp. 559 - 567
ATF3 (activating transcription factor 3) gene encodes a member of the ATF/CREB (cAMP-response-element-binding protein) family of transcription factors. Its... 
Mitogen activated protein kinase (MAPK) | Activating transcription factor 3 (ATF3) | p38 | Stress response | Stress kinase | MAPK kinase (MKK) | APOPTOSIS | activating transcription factor 3 (ATF3) | stress kinase | PHOSPHORYLATION | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION FACTOR-3 | mitogen activated protein kinase (MAPK) | JUN NH2-TERMINAL KINASE | INDUCTION | stress response | VASCULAR ENDOTHELIAL-CELLS | C-JUN | STRESS | INHIBITOR | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Gene Expression Regulation | Activating Transcription Factor 3 - biosynthesis | Cercopithecus aethiops | JNK Mitogen-Activated Protein Kinases - metabolism | Imidazoles - pharmacology | MAP Kinase Kinase 7 - metabolism | Transcription Factors - metabolism | Animals | Mitogen-Activated Protein Kinases - physiology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Enzyme Induction - drug effects | Anisomycin - pharmacology | Flavonoids - pharmacology | Pyridines - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Enzyme Activation | HeLa Cells | COS Cells | Activating Transcription Factor 3 - genetics | Index Medicus | IL-1β, interleukin 1β | JNK, c-Jun N-terminal kinase | DTT, dithiothreitol | shRNA, small-hairpin RNA | ERK, extracellular-signal-regulated kinase | SAPK, stress-activated protein kinase | DMEM, Dulbecco's modified Eagle's medium | ERK kinase 1 | CREB, CRE-binding protein | RT, reverse transcriptase | gadd153, growth-arrest and DNA-damage-inducible protein 153 | TNFα, tumour necrosis factor α | enhancer-binding protein | EBP-homologous protein 10 | GAPDH, glyceraldehyde-3-phosphate dehydrogenase | CRE, cAMP-response element | GST, glutathione S-transferase | HEK-293 cells, human embryonic kidney 293 cells | tetO, tet operator | NF-κB, nuclear factor κB | EBP, CCAAT | DN, dominant negative | FBS, fetal bovine serum | β-Gal, β-galactosidase | MKK, MAPK kinase | HA, haemagglutinin | CA, constitutively active | IP–kinase, immunoprecipitation coupled with kinase | MEK1, MAPK | ATF, activating transcription factor | Chop10, C | TGF-β, transforming growth factor-β | MEF, mouse embryonic fibroblast | MAPK, mitogen-activated protein kinase
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2014, Volume 15, Issue 20, pp. 8539 - 8548
Mitogen-activated protein kinase (MAPK) is an important signaling pathway in living beings in response to extracellular stimuli. There are 5 main subgroups... 
Mechanisms of action | Treatment | MAPK | Tumor development | treatment | PTEN LOSS | P38 MAPK | tumor development | mechanisms of action | BREAST-CANCER | LIVER-CANCER | TARGETED THERAPIES | IN-VITRO | MELANOMA | ONCOLOGY | GASTRIC-CANCER | PATHWAY | PROSTATE-CANCER
Journal Article
Circulation Research, ISSN 0009-7330, 02/2014, Volume 114, Issue 4, pp. 616 - 625
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 03/2005, Volume 111, Issue 9, pp. 1184 - 1191
Background - Transplantation of endothelial progenitor cells (EPCs) improves neovascularization after ischemia, but patients with coronary artery disease (... 
Angiogenesis | Glucose | Tumor necrosis factor-α | Stem cells | Mitogen-activated protein kinases | stem cells | glucose | CORONARY-ARTERY DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | angiogenesis | MAP KINASE | PROLIFERATION | TRANSPLANTATION | tumor necrosis factor-alpha | PATHWAY | mitogen-activated protein kinases | INCREASE | PERIPHERAL VASCULAR DISEASE | DYSFUNCTION | INHIBITORS | HEMATOLOGY | EXPRESSION | Cell Count | Cells, Cultured - cytology | Humans | Middle Aged | Ischemia - enzymology | Molecular Sequence Data | Coronary Disease - epidemiology | Male | Transplantation, Heterologous | Stem Cells - cytology | Stem Cell Transplantation | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Isoquinolines - pharmacology | Protein Processing, Post-Translational - drug effects | Stem Cells - enzymology | Adult | Female | Cell Differentiation | Phosphorylation - drug effects | Ischemia - pathology | Amino Acid Sequence | Cells, Cultured - drug effects | p38 Mitogen-Activated Protein Kinases - physiology | Comorbidity | Risk Factors | Glucose - pharmacology | Imidazoles - pharmacology | Sulfonamides - pharmacology | Cell Division - drug effects | Transcription Factors - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Coronary Disease - pathology | Animals | Coronary Disease - enzymology | Signal Transduction - drug effects | Hindlimb - blood supply | Mice, Nude | Activating Transcription Factor 2 | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Cyclic AMP Response Element-Binding Protein - metabolism | Aged | Mice | Pyridines - pharmacology | Apoptosis | Index Medicus | Abridged Index Medicus
Journal Article