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Journal Article
SCIENCE, ISSN 0036-8075, 08/2012, Volume 337, Issue 6096, pp. 843 - 846
Proteasomes are the major energy-dependent proteolytic machines in the eukaryotic and archaeal domains of life. To execute protein degradation, the 20S core... 
REGULATORY PARTICLE | ATPASE | P97/VCP | MULTIDISCIPLINARY SCIENCES | N-DOMAIN | DEGRADATION | P97
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 01/2012, Volume 1823, Issue 1, pp. 130 - 137
Journal Article
SCIENCE, ISSN 0036-8075, 08/2019, Volume 365, Issue 6452, pp. 502 - 502
The cellular machine Cdc48 functions in multiple biological pathways by segregating its protein substrates from a variety of stable environments such as... 
SYSTEM | MECHANISM | P97/VCP | MULTIDISCIPLINARY SCIENCES | AAA ATPASE | CRYO-EM STRUCTURE | BINDING | P97 | FEATURES
Journal Article
Detection of Antibodies to the 97 kDa Component of Toxoplasma gondii   in Samples of Human Serum, 12/2002
This study was carried out to investigate the immune response against 97 kDa (p97) molecular marker of Toxoplasma gondii   that has been characterized as a... 
Toxoplasma - enzime-linked immunosorbent assay - Western blot - p97
Journal
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2019, Volume 62, Issue 5, pp. 2814 - 2829
Inhibitors of human p97 (also known as valosin-containing protein) have been actively pursued because of their potential therapeutic applications in cancer and... 
PHOSPHATE | CHEMISTRY, MEDICINAL | COVALENT INHIBITORS | PROTEIN | UBIQUITIN | REACTIVITY | VCP/P97 | BINDING | DERIVATIVES | AAA-ATPASE P97 | REVEALS
Journal Article
FEBS Letters, ISSN 0014-5793, 08/2018, Volume 592, Issue 16, pp. 2680 - 2692
Intracellular protein aggregation is characterized by accumulation of misfolded proteins. Chaperones, degradation machineries, and quality-control mechanisms... 
ase | disaggregase | VCP | ATP | Huntingtin‐exon1 aggregates | p97 | VCP/p97 | Huntingtin-exon1 aggregates | ATPase
Journal Article
FRONTIERS IN MICROBIOLOGY, ISSN 1664-302X, 09/2019, Volume 10
The evolutionarily conserved AAA+ ATPase valosin-containing protein (VCP) was previously shown to be a proviral host factor for several viruses from different... 
VCP | INTERPLAY | host factor | VCP/p97 | MICROBIOLOGY | alphavirus | proviral factor | CONTAINING PROTEIN VCP/P97 | CANCER | chikungunya | P97 | SINDBIS VIRUS | PROTEASOME | AAA-ATPASE | INHIBITORS
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 09/2008, Volume 105, Issue 35, pp. 12879 - 12884
Since cdc48 mutants were isolated by the first genetic screens for cell division cycle (cdc) mutants in yeast, the requirement of the chaperone-like ATPase... 
genome stability | AAA-ATPASE P97/VCP | ATL-1/ATR | C. elegans | UBIQUITIN | MULTIDISCIPLINARY SCIENCES | CDC48/P97 | P97 | MEMBRANE-FUSION | MITOSIS | UNFOLDED PROTEIN RESPONSE | CAENORHABDITIS-ELEGANS | C-ELEGANS | CDC-48/p97 | RECOMBINATION PROTEIN
Journal Article
SCIENCE, ISSN 0036-8075, 02/2016, Volume 351, Issue 6275, pp. 871 - 875
p97 is a hexameric AAA+ adenosine triphosphatase (ATPase) that is an attractive target for cancer drug development. We report cryo-electron microscopy... 
SYSTEM | DOMAIN | ANALOGS | P97/VCP | MULTIDISCIPLINARY SCIENCES | AAA-ATPASE | BINDING
Journal Article
Neuron, ISSN 0896-6273, 12/2010, Volume 68, Issue 5, pp. 857 - 864
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2014, Volume 111, Issue 17, pp. 6128 - 6128
From microbes to humans, proteolytic machines called proteasomes cleave proteins that are damaged or unnecessary into peptide fragments. Proteasomes minimally... 
PNAS Plus: Significance Statements | P97/VCP | Dynamic wobbling model | Biological Sciences | AAA+ protease | VCP | PNAS Plus | dynamic wobbling model | p97
Journal Article
Journal Article
Placenta, ISSN 0143-4004, 07/2018, Volume 67, pp. 45 - 53
Autophagy increases in placenta-related obstetrical diseases such as preeclampsia and intrauterine growth retardation but the regulation of autophagy by... 
Ubiquitin | Human placenta | p97/VCP | Autophagy | Preeclampsia | VALOSIN-CONTAINING PROTEIN | p97/ VCP | VCP/P97 | DEVELOPMENTAL BIOLOGY | HYPOXIA | CELL-DEATH | OBSTETRICS & GYNECOLOGY | REPRODUCTIVE BIOLOGY | PROTEASOME | DEGRADATION | MUTATIONS | LC3 | VCP DISEASE
Journal Article