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Journal of Controlled Release, ISSN 0168-3659, 11/2019, Volume 313, pp. 70 - 79
The R8/YSK-MEND shows a high gene expression in the spleen with a high spleen/liver ratio and B cell targeting. A strong anti-tumor effect was observed in mice... 
Spleen | Gene delivery | YSK05 | pDNA
Journal Article
Colloids and Surfaces B: Biointerfaces, ISSN 0927-7765, 11/2019, Volume 183, p. 110417
The field of gene therapy still attracts great interest due to its potential therapeutic effect towards the most deadly diseases, such as cancer. For cancer... 
Gene delivery | Optimal peptide/pDNA formulations | Design of experiments | pDNA condensation | peptide/pDNA vectors | Cancer gene therapy | SYSTEM | MATERIALS SCIENCE, BIOMATERIALS | COMPLEXES | CHEMISTRY, PHYSICAL | POLYETHYLENIMINE | SIRNA DELIVERY | NANOPARTICLES | CO-DELIVERY | BIOPHYSICS | ARGININE | RESIDUES | Life Sciences | Cellular Biology
Journal Article
Colloids and Surfaces B: Biointerfaces, ISSN 0927-7765, 06/2019, Volume 178, pp. 430 - 438
The development of delivery systems based on cell penetrating peptides represents an incredible asset and may deeply contribute for the evolution of therapies... 
Controlled/sustained release | Cell penetrating peptides | Drug/gene co-delivery | Cationic surfactants | pDNA compaction | pDNA-surfactant complexes | MATERIALS SCIENCE, BIOMATERIALS | GENE DELIVERY | CHEMISTRY, PHYSICAL | POLYETHYLENIMINE | HYALURONIC-ACID | NANOPARTICLES | ORDER | TAT-PEPTIDE | BIOPHYSICS | BINDING | GEMINI SURFACTANTS
Journal Article
Chemistry of Materials, ISSN 0897-4756, 05/2016, Volume 28, Issue 10, pp. 3318 - 3326
Selective functionalization of the external surface of porous nanoparticles is of great interest for numerous potential applications in the field of... 
PDNA | METAL-ORGANIC FRAMEWORKS | MIL-100(FE) | STABILITY | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY | CHEMISTRY, PHYSICAL | MESOPOROUS SILICA NANOPARTICLES | MEDIA | FLUORESCENCE CORRELATION SPECTROSCOPY | CANCER | DELIVERY
Journal Article
Journal of Chromatography A, ISSN 0021-9673, 09/2019, p. 460571
Journal Article
Journal of Biotechnology, ISSN 0168-1656, 2010, Volume 150, pp. 463 - 463
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 10/2019, Volume 141, Issue 40, pp. 15804 - 15817
Cellular delivery of biomacromolecules is vital to medical research and therapeutic development. Cationic polymers are promising and affordable candidate... 
NANOPARTICLES | MOLECULAR-EXCHANGE | IN-VIVO | POLYMER | BLOCK-COPOLYMER MICELLES | SIRNA | PDNA BINDING | CHEMISTRY, MULTIDISCIPLINARY | TRANSFECTION EFFICACY | NONVIRAL VECTORS
Journal Article
Macromolecules, ISSN 0024-9297, 11/2016, Volume 49, Issue 22, pp. 8397 - 8406
Epoxy resins are ubiquitous in high-performance composite applications because of their excellent mechanical strength, thermal and chemical resistance, strong... 
PDNA | HYDROGELS | POLYMER SCIENCE | ACID | GENE DELIVERY | CARBOHYDRATE-CONTAINING POLYCATIONS | BIOMACROMOLECULES | POLYMER LENGTH | SIRNA DELIVERY | MECHANICAL-PROPERTIES | WATER
Journal Article
Journal of Bioscience and Bioengineering, ISSN 1389-1723, 03/2014, Volume 117, Issue 3, pp. 336 - 342
Two engineered Escherichia coli strains, designated VH33 and VH34, were compared to their parent strain W3110 in chemostat mode during plasmid DNA (pDNA)... 
Overflow metabolism | Chemostat cultures | Metabolic fluxes | Pyruvate kinase | PDNA vaccines
Journal Article
RSC Advances, ISSN 2046-2069, 08/2015, Volume 5, Issue 90, pp. 74102 - 74106
A trehalose-based polycation that contains lanthanide-chelate domains has been examined as a theranostic vehicle for siRNA delivery. By chelating the polymers... 
NANOPARTICLES | PDNA | FLUORESCENCE | GLYCOPOLYMERS | LUMINESCENCE | COMPLEXES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 11/2014, Volume 193, pp. 316 - 323
We report on the development of a multifunctional envelope-type nano device (MEND) based on our packaging concept “Programmed packaging” to control not only... 
Active targeting | MEND | siRNA | pDNA | Gene therapy | Drug delivery system
Journal Article
Current Opinion in Colloid & Interface Science, ISSN 1359-0294, 02/2019, Volume 39, pp. 11 - 23
With its nearly unrestricted possibilities, gene therapy attracts more and more significance in modern-day research. The only issue still seeming to hold back... 
Nanogels | Polymeric carriers | Gene delivery | siRNA | Nucleic acids | pDNA | Genetic research | Genetic vectors | Gene therapy | Pharmacy | Genes | Polymeric Carriers | Nucleic Acids | Gene Delivery
Journal Article
ACS Macro Letters, ISSN 2161-1653, 07/2017, Volume 6, Issue 7, pp. 768 - 774
Oxaborole-based polymers are stimuli-responsive materials that can reversibly interact with diols at pH values higher than their pK a. The strong binding of... 
NANOPARTICLES | POLYPLEXES | DESIGN | PDNA | POLYMER SCIENCE | TRANSFECTION | PROGRESS | SIRNA DELIVERY | KNOCKDOWN | EGFR | PRINCIPLES
Journal Article
Macromolecular bioscience, ISSN 1616-5187, 1/2016, Volume 16, Issue 1, pp. 63 - 73
A family of Pluronic-based, cholesterol end-capped cationic polyrotaxanes (PR + ), threaded with 2-hydroxypropyl-β-cyclodextrin (HPCD), was synthesized for... 
β-Cyclodextrins | Gene delivery | Polyrotaxane | Transfection | pDNA
Journal Article
African Journal of Biotechnology, ISSN 1684-5315, 01/2012, Volume 11, Issue 5, pp. 1231 - 1239
DNA vaccination and gene therapy using plasmid DNA [pDNA] are emerging as the tools of choice for preventing and treating debilitating diseases. A crucial... 
Plasmid DNA [pDNA] | Vaccines | gWizHBs
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 10/2019, Volume 569, p. 118570
Small interfering RNA (siRNA) represents a new class of therapeutic agents. Its successful intracellular delivery is a major challenge. Lipo-oligomeric... 
Eglin 5 | Polyplex | Pretubulysin | siRNA | EGFR targeting | PEG shielding | Combination therapy | PDNA | ACID | COMBINATION | CHEMOTHERAPY | NANOPARTICLES | THERAPY | RNAI THERAPEUTICS | PROGRESS | PHARMACOLOGY & PHARMACY | TUBULYSIN PRECURSOR
Journal Article
Macromolecules, ISSN 0024-9297, 09/2016, Volume 49, Issue 17, pp. 6644 - 6654
We investigate the complexation of poly­(styrenesulfonate) with micelles containing both cationic and hydrophilic blocks in their coronas. Five distinct... 
NANOPARTICLES | INTERPOLYELECTROLYTE COMPLEXES | LINEAR POLYELECTROLYTES | PDNA DELIVERY | CO-DELIVERY | POLYMER SCIENCE | DNA | WATER-SOLUBLE COMPLEXES | OPPOSITE CHARGE | BLOCK-COPOLYMER MICELLES | SIRNA DELIVERY
Journal Article
Colloids and Surfaces B: Biointerfaces, ISSN 0927-7765, 01/2020, Volume 185, p. 110610
Journal Article
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