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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 48, pp. 18907 - 18912
Journal Article
Nature Reviews Gastroenterology and Hepatology, ISSN 1759-5045, 05/2017, Volume 14, Issue 5, pp. 296 - 304
Journal Article
Oncogene, ISSN 0950-9232, 04/2013, Volume 32, Issue 15, pp. 1950 - 1958
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 147, Issue 5, pp. 1119 - 1133.e4
Background & Aims Although smoking is a leading risk factor for pancreatic ductal adenocarcinoma (PDAC), little is known about the mechanisms by which smoking... 
Gastroenterology and Hepatology | Metastasis | Pancreas | Progenitor Cells | Mouse Model | METFORMIN | STEM-CELLS | DUCTAL ADENOCARCINOMA | PROLIFERATION | EPITHELIAL-MESENCHYMAL TRANSITION | ADULT-MOUSE PANCREAS | ACETYLCHOLINE-RECEPTORS | K-RAS | GROWTH | DIFFERENTIATION | GASTROENTEROLOGY & HEPATOLOGY | Pancreatic Neoplasms - metabolism | Neoplastic Stem Cells - drug effects | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Carcinoma, Pancreatic Ductal - metabolism | Epithelial-Mesenchymal Transition - drug effects | Mice, 129 Strain | Carcinoma, Pancreatic Ductal - genetics | Neoplastic Stem Cells - metabolism | Time Factors | Cell Transformation, Neoplastic - genetics | Neoplastic Stem Cells - pathology | Pancreatic Neoplasms - chemically induced | Liver Neoplasms - secondary | Nicotinic Agonists - toxicity | Proto-Oncogene Proteins c-akt - metabolism | Neoplastic Cells, Circulating - drug effects | GATA6 Transcription Factor - deficiency | Liver Neoplasms - genetics | Pancreatic Neoplasms - pathology | Pancreas - pathology | alpha7 Nicotinic Acetylcholine Receptor - genetics | Pancreas - metabolism | Mice, Knockout | Acinar Cells - pathology | Signal Transduction - drug effects | Mice, Nude | Liver Neoplasms - metabolism | Cell Line, Tumor | alpha7 Nicotinic Acetylcholine Receptor - metabolism | Mutation | Carcinoma, Pancreatic Ductal - secondary | Carcinoma, Pancreatic Ductal - chemically induced | Neoplastic Cells, Circulating - pathology | Neoplastic Cells, Circulating - metabolism | Cell Transformation, Neoplastic - chemically induced | Extracellular Signal-Regulated MAP Kinases - metabolism | Carcinoma, Pancreatic Ductal - prevention & control | Tumor Suppressor Protein p53 - genetics | Transfection | Proto-Oncogene Proteins p21(ras) - deficiency | Gene Expression Regulation, Neoplastic - drug effects | Pancreatic Neoplasms - prevention & control | Tumor Cells, Cultured | Proto-Oncogene Proteins p21(ras) - metabolism | Acinar Cells - metabolism | Cell Dedifferentiation - drug effects | Metformin - pharmacology | Mice, Inbred C57BL | Tumor Suppressor Protein p53 - metabolism | Pancreas - drug effects | Pancreatic Neoplasms - genetics | Nicotine - toxicity | Cell Transformation, Neoplastic - metabolism | Proto-Oncogene Proteins c-myc - metabolism | GATA6 Transcription Factor - metabolism | Animals | Acinar Cells - drug effects | GATA6 Transcription Factor - genetics | Cell Transformation, Neoplastic - pathology | Pancreatic cancer | Stem cells | Nicotine
Journal Article
eLife, ISSN 2050-084X, 04/2014, Volume 2014, Issue 3, p. e01846
Direct lineage conversion of adult cells is a promising approach for regenerative medicine. A major challenge of lineage conversion is to generate specific... 
PLURIPOTENT STEM-CELLS | PROGENITORS | DEFINED FACTORS | MAFB | BETA-CELLS | TRANSCRIPTION | BIOLOGY | DIRECT CONVERSION | NEURONS | HUMAN FIBROBLASTS | GENERATION | Homeodomain Proteins - metabolism | Humans | Cellular Reprogramming | Luminescent Proteins - biosynthesis | Maf Transcription Factors, Large - metabolism | Insulin-Secreting Cells - metabolism | Transfection | Basic Helix-Loop-Helix Transcription Factors - metabolism | Maf Transcription Factors, Large - genetics | Pancreas, Exocrine - cytology | Time Factors | Gene Expression Regulation, Developmental | Glucagon-Secreting Cells - metabolism | HEK293 Cells | Trans-Activators - genetics | Glucagon-Secreting Cells - physiology | Cell Transdifferentiation | Genes, Reporter | Insulin-Secreting Cells - physiology | Basic Helix-Loop-Helix Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Mice, Knockout | Pancreas, Exocrine - physiology | Nerve Tissue Proteins - metabolism | Cell Lineage | Animals | Somatostatin-Secreting Cells - physiology | Luminescent Proteins - genetics | Trans-Activators - metabolism | Pancreas, Exocrine - metabolism | Somatostatin-Secreting Cells - metabolism | Acinar cells | Transcription factors | Glucagon | Insulin | Studies | Polymerase chain reaction | Regeneration | Rodents | Stem cells | DNA methylation | Fibroblasts | Somatostatin | Islets of Langerhans | Pancreas | Deoxyribonucleic acid--DNA
Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 2011, Volume 141, Issue 4, pp. 1451 - 1462.e6
Journal Article
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 12/2012, Volume 36, Issue 12, pp. 1782 - 1795
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2015, Volume 112, Issue 45, pp. E6166 - E6174
Journal Article