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Science, ISSN 0036-8075, 06/2019, Volume 364, Issue 6446, p. 1148
Journal Article
Cell Metabolism, ISSN 1550-4131, 02/2017, Volume 25, Issue 2, p. 223
Diabetes is a growing epidemic, and many patients depend on insulin injections to control the disease and minimize long-term complications. In a recent... 
Pancreatic beta cells | Genetically modified organisms
Journal Article
Diabetic Medicine, ISSN 0742-3071, 03/2018, Volume 35, Issue S1, pp. 23 - 24
Journal Article
Diabetologia, ISSN 0012-186X, 1/2018, Volume 61, Issue 1, pp. 39 - 42
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s00125-017-4443-8 
Medicine & Public Health | Human Physiology | Metabolic Diseases | Beta cell | Internal Medicine | Inflammation | Purinergic | Islet | ATP | Insulin | Macrophage | ACTIVATION | MACROPHAGES | RECEPTOR | PROLIFERATION | NLRP3 INFLAMMASOME | RELEASE | GLUCOSE | ENDOCRINOLOGY & METABOLISM | IL-1-BETA | EXPRESSION | Pancreatic beta cells | Research institutes | Beta cells
Journal Article
Journal Article
Diabetologia, ISSN 0012-186X, 6/2009, Volume 52, Issue 6, pp. 1083 - 1086
Journal Article
Nature Reviews Endocrinology, ISSN 1759-5029, 01/2015, Volume 11, Issue 1, p. 5
The race to generate [beta] cells from stem cells has taken another big turn. We can already generate definitive endoderm from human embryonic stem cells and... 
Pancreatic beta cells | Usage | Cell research | Stem cells | Research | Properties | Cell differentiation
Journal Article
Nature Reviews Endocrinology, ISSN 1759-5029, 04/2017, Volume 13, Issue 4, p. 189
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 07/2013, Volume 12, Issue 7
Journal Article
2018, ISBN 9811300011, 73
Since the 1970s, there has been much discussion about the 'glucoreceptor' and 'substrate site' and which of these two is the dominant theory, but new findings... 
Glucose | Pancreatic beta cells | Human Physiology | Endocrinology | Biomedicine | Cellular signal transduction
eBook
Journal of Diabetes Investigation, ISSN 2040-1116, 09/2017, Volume 8, Issue 5, p. 656
Journal Article
Cell Metabolism, ISSN 1550-4131, 05/2019, Volume 29, Issue 5, pp. 1045 - 1060.e10
Type 1 diabetes (T1D) is an organ-specific autoimmune disease characterized by hyperglycemia due to progressive loss of pancreatic beta cells. Immune-mediated... 
senolytics | type 1 diabetes | cellular senescence | SASP | DNA damage | beta cells | CLEARANCE | SECRETORY PHENOTYPE | TECHNOLOGIES | INHIBITION | DISEASE | ENDOCRINOLOGY & METABOLISM | SURVEILLANCE | CELLULAR SENESCENCE | PROGRESSION | REVEALS | DEVELOP | CELL BIOLOGY | Prevention | Electrical engineering | Pancreatic beta cells | Hyperglycemia | Type 1 diabetes | Analysis | Cells
Journal Article
Diabetologia, ISSN 0012-186X, 1/2008, Volume 51, Issue 1, pp. 91 - 100
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2013, Volume 369, Issue 8, pp. 777 - 779
Finding a way to boost the numbers of pancreatic insulin-secreting beta cells is a major goal of diabetes research. A step toward this goal is the recent... 
MEDICINE, GENERAL & INTERNAL | INSULIN-RESISTANCE | Peptide Hormones - metabolism | Insulin-Secreting Cells - metabolism | Animals | Cell Proliferation | Humans | Pancreas - cytology | Female | Male | Cell proliferation | Insulin resistance | Pancreatic beta cells | Research | Beta cells | Diabetes mellitus | Liver | Rodents | Diabetes | Pancreas | Insulin
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2011, Volume 108, Issue 28, pp. 11692 - 11697
Type 1 diabetes (T1D) is an autoimmune disease characterized by insulitis and islet β-cell loss. Thus, an effective therapy may require β-cell restoration and... 
Depolarization | Antiinflammatories | Cytokines | Diabetes complications | Islet cells | Mice | Diabetes | Type 2 diabetes mellitus | Insulin | Type 1 diabetes mellitus | Inflammation | Regulatory T-cell | AMINOBUTYRIC-ACID GABA | insulin | RAT | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | RECEPTOR | RELEASE | inflammation | AUTOIMMUNITY | regulatory T-cell | MICE | EXPRESSION | T-CELLS | ONSET | Apoptosis - drug effects | Male | Phosphatidylinositol 3-Kinases - metabolism | T-Lymphocytes, Regulatory - immunology | gamma-Aminobutyric Acid - physiology | Inflammation Mediators - metabolism | Female | Diabetes Mellitus, Type 1 - immunology | Proto-Oncogene Proteins c-akt - metabolism | Immunosuppressive Agents - pharmacology | Insulin-Secreting Cells - physiology | Membrane Potentials - drug effects | Hyperglycemia - prevention & control | Diabetes Mellitus, Type 1 - physiopathology | Diabetes Mellitus, Type 1 - pathology | gamma-Aminobutyric Acid - pharmacology | Mice, Transgenic | Insulin-Secreting Cells - immunology | Diabetes Mellitus, Type 1 - drug therapy | Regeneration - drug effects | T-Lymphocytes, Regulatory - drug effects | Animals | Insulin-Secreting Cells - drug effects | Signal Transduction - drug effects | Calcium Signaling - drug effects | Mice, Inbred NOD | Cell Proliferation - drug effects | Insulin-Secreting Cells - pathology | Cytokines - biosynthesis | GABA | Physiological aspects | Pancreatic beta cells | Research | Type 1 diabetes | Biological Sciences
Journal Article
Diabetologia, ISSN 0012-186X, 10/2015, Volume 58, Issue 10, pp. 2307 - 2316
Journal Article