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Molecular Cancer Therapeutics, ISSN 1535-7163, 08/2007, Volume 6, Issue 8, pp. 2158 - 2167
Insulin-like growth factor-I receptor (IGF-IR) and its ligands, IGF-I and IGF-II, are up-regulated in a variety of human cancers. In tumors, such as... 
Protein tyrosine kinases | Small Molecules and Other Therapeutics Agents | Autocrine-paracrine signaling | COLORECTAL-CANCER RISK | BREAST-CANCER | SARCOMA-CELLS | ONCOLOGY | PLASMA-LEVELS | IGF-BINDING PROTEIN-3 | FACTOR SYSTEM | ANTIBODY | ANTITUMOR-ACTIVITY | EXPRESSION | TUMORIGENESIS | Receptor, IGF Type 1 - metabolism | Receptor, IGF Type 1 - antagonists & inhibitors | Humans | Pyrazines - administration & dosage | Imidazoles - chemistry | Imidazoles - administration & dosage | Autocrine Communication - drug effects | Antineoplastic Agents - administration & dosage | Imidazoles - pharmacokinetics | Protein Kinase Inhibitors - chemistry | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Phosphorylation - drug effects | Protein Kinase Inhibitors - pharmacokinetics | Tumor Stem Cell Assay | Imidazoles - pharmacology | Antineoplastic Agents - chemistry | Enzyme Activation - drug effects | Insulin-Like Growth Factor II - metabolism | Blood Glucose - drug effects | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Pyrazines - chemistry | Animals | Signal Transduction - drug effects | Mice, Nude | Pyrazines - pharmacokinetics | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Colorectal Neoplasms - pathology | Pyrazines - pharmacology
Journal Article
American Journal of Pathology, ISSN 0002-9440, 08/1999, Volume 155, Issue 2, pp. 421 - 428
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, p. e109305
We have investigated and compared the neurotrophic activity of human dental pulp stem cells (hDPSC), human bone marrow-derived mesenchymal stem cells (hBMSC)... 
SURVIVAL | OPTIC-NERVE | IN-VITRO | NEUROTROPHIC FACTOR | MULTIDISCIPLINARY SCIENCES | AXON REGENERATION | RATS | SPINAL-CORD | EXPERIMENTAL GLAUCOMA | BRAIN | TRANSPLANTATION | Nerve Growth Factor - secretion | Brain-Derived Neurotrophic Factor - secretion | Cell- and Tissue-Based Therapy - methods | Neuroprotection | Vascular Endothelial Growth Factor A - biosynthesis | Nerve Growth Factor - biosynthesis | Neurites - physiology | Coculture Techniques | Humans | Adipose Tissue - cytology | Male | Dental Pulp - metabolism | Retinal Ganglion Cells - metabolism | Vascular Endothelial Growth Factor A - secretion | Adipose Tissue - metabolism | Paracrine Communication - physiology | Retinal Ganglion Cells - cytology | Axotomy | Mesenchymal Stromal Cells - cytology | Brain-Derived Neurotrophic Factor - biosynthesis | Bone Marrow Cells - cytology | Dental Pulp - cytology | Mesenchymal Stromal Cells - metabolism | Rats | Rats, Sprague-Dawley | Animals | Primary Cell Culture | Bone Marrow Cells - metabolism | Fc receptors | Platelet-derived growth factor | Stem cells | Nerve growth factor | Comparative analysis | Ganglion | Vascular endothelial growth factor | Health aspects | Enzyme-linked immunosorbent assay | Neurosciences | Spinal cord | Mesenchyme | Neurobiology | Paracrine signalling | Stem cell transplantation | Retina | Nervous system | Neurotrophin 3 | Receptors | Rodents | Bone marrow | Conditioning | Ganglion cells | Growth factors | Glial cell line-derived neurotrophic factor | Optic nerve | Cytokines | Axonogenesis | Dentistry | Gene expression | Survival | Medicine | Retinal ganglion cells | Brain research | Brain-derived neurotrophic factor | Inhibitors | Apoptosis | Dental pulp
Journal Article
PLoS Medicine, ISSN 1549-1277, 01/2008, Volume 5, Issue 1, pp. 0123 - 0138
Background Important support functions, including promotion of tumor growth, angiogenesis, and invasion, have been attributed to the different cell types... 
HUMAN BREAST-CARCINOMA | MEDICINE, GENERAL & INTERNAL | TGF-BETA | GROWTH-FACTOR-RECEPTOR | SQUAMOUS CARCINOGENESIS | TYPE-16 TRANSGENIC MICE | FACTOR-BETA-RECEPTOR | CELL INVASION | MOUSE MODEL | TISSUE STROMA | CERVICAL-CANCER | Fibroblast Growth Factor 7 - physiology | Fibroblasts - enzymology | Uterine Cervical Neoplasms - blood supply | Humans | Carcinoma - virology | Neoplasm Proteins - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Receptors, Platelet-Derived Growth Factor - physiology | Proto-Oncogene Proteins c-kit - biosynthesis | Neovascularization, Pathologic - physiopathology | Neoplasm Proteins - genetics | Carcinoma - drug therapy | Estradiol - administration & dosage | Receptors, Platelet-Derived Growth Factor - genetics | Mice, Transgenic | Piperazines - therapeutic use | Uterine Cervical Neoplasms - physiopathology | Pyrimidines - pharmacology | Fibroblast Growth Factor 7 - biosynthesis | Piperazines - pharmacology | Carcinoma - physiopathology | Stromal Cells - secretion | Fibroblast Growth Factor 2 - genetics | Neovascularization, Pathologic - drug therapy | Fibroblasts - drug effects | Carcinoma - blood supply | Mice | Fibroblasts - secretion | Epithelial Cells - metabolism | Neoplasm Proteins - physiology | Platelet-Derived Growth Factor - genetics | Human papillomavirus 16 | Paracrine Communication - physiology | Stromal Cells - enzymology | Stromal Cells - drug effects | Female | Proto-Oncogene Proteins c-kit - genetics | Antineoplastic Agents - pharmacology | Fibroblast Growth Factor 2 - physiology | Receptors, Platelet-Derived Growth Factor - antagonists & inhibitors | Neoplasm Proteins - biosynthesis | Pericytes - metabolism | Fibroblast Growth Factor 2 - biosynthesis | Uterine Cervical Neoplasms - drug therapy | Mice, Inbred Strains | Imatinib Mesylate | Fibroblast Growth Factor 7 - genetics | Animals | Estradiol - toxicity | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Paracrine Communication - drug effects | Uterine Cervical Neoplasms - virology | Protein Kinase Inhibitors - pharmacology | Benzamides | Platelet-Derived Growth Factor - physiology | Platelet-Derived Growth Factor - antagonists & inhibitors | Proteins | Medical research | Human papillomavirus | Cervical cancer | Tumors | Index Medicus | Oncology | Gynecological | Chemotherapy | Cancer
Journal Article
Nature, ISSN 0028-0836, 01/2018, Volume 553, Issue 7689, pp. 461 - 466
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2013, Volume 123, Issue 1, pp. 189 - 205
Journal Article