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SCIENCE, ISSN 0036-8075, 11/2018, Volume 362, Issue 6414, pp. 521 - 522
Journal Article
Annual Review of Pharmacology and Toxicology, ISSN 0362-1642, 01/2017, Volume 57, pp. 437 - 454
Journal Article
Journal Article
Experimental Cell Research, ISSN 0014-4827, 11/2019, Volume 384, Issue 1, p. 111547
Traumatic brain injury (TBI) is common and often fatal in current times. The role of poly(adenosine diphosphate-ribose) polymerase (PARP)-induced cell death... 
PARP | Traumatic brain injury | p53-MDM2 pathway | Parthanatos | Iduna | AIF | OXIDATIVE STRESS | ACTIVATION | HIPPOCAMPAL | DEATH | MESSENGER | P53 | CELL BIOLOGY | INTERACT | TRAUMATIC BRAIN-INJURY | ONCOLOGY | DEGRADATION | EXPRESSION
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2014, Volume 111, Issue 28, pp. 10209 - 10214
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 02/2019, Volume 131, pp. 251 - 263
Cerebral ischemia induces neuronal cell death in different ways and mitochondrial dysfunction is an important cause. Astragaloside IV (AIV) is a natural... 
Cerebral ischemia | Astragaloside IV | Hexokinase-II | Parthanatos | Apoptosis | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-DEATH | EXCITOTOXICITY | PATHWAY | ENDOCRINOLOGY & METABOLISM | DYSFUNCTION | ENERGY-METABOLISM
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 12/2018, Volume 129, pp. 569 - 581
Retinal degeneration is a major cause of severe vision loss and irreversible blindness and is characterized by progressive damage to retinal photoreceptor... 
PATHOGENESIS | APOPTOSIS | OXIDATIVE STRESS | PIGMENT EPITHELIAL-CELLS | MITOCHONDRIAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCRINOLOGY & METABOLISM | PARTHANATOS | FACTOR-KAPPA-B | MECHANISMS | SIRT1 | DAMAGE | Macular degeneration | Biochemistry | Cell death | Resveratrol | Heme | Blindness
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 09/2019, Volume 20, Issue 18, p. 4379
The term necrosis is commonly applied to cells that have died via a non-specific pathway or mechanism but strictly is the description of the degradation... 
APOPTOSIS | oncosis | NECROPTOSIS | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | CHEMISTRY, MULTIDISCIPLINARY | accidental cell death | DDR | NECROSIS | parthanatos | flow cytometry | NECROBIOLOGY | DEATH RECOMMENDATIONS
Journal Article
Science, ISSN 0036-8075, 10/2016, Volume 354, Issue 6308, pp. aad6872 - aad6872
Inhibition or genetic deletion of poly(ADP-ribose) (PAR) polymerase-1 (PARP-1) is protective against toxic insults in many organ systems. The molecular... 
APOPTOSIS | MIGRATION-INHIBITORY FACTOR | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | FACTOR MIF | PARTHANATOS | CYTOKINE | ENZYMATIC-ACTIVITY | TAUTOMERASE | IDENTIFICATION | ENDONUCLEASE-G | Chromatin - metabolism | Mitochondria - enzymology | Oxidative Stress | Glutamic Acid - genetics | Humans | Apoptosis - genetics | Macrophage Migration-Inhibitory Factors - metabolism | Deoxyribonucleases - metabolism | Stroke - genetics | Cell Nucleus - enzymology | Macrophage Migration-Inhibitory Factors - genetics | Base Sequence | DNA Fragmentation | DNA Damage - genetics | Macrophage Migration-Inhibitory Factors - chemistry | Active Transport, Cell Nucleus | Intramolecular Oxidoreductases - metabolism | Nucleic Acid Conformation | Apoptosis Inducing Factor - metabolism | Deoxyribonucleases - chemistry | Amino Acid Sequence | Catalytic Domain | Intramolecular Oxidoreductases - chemistry | DNA, Single-Stranded - metabolism | Poly (ADP-Ribose) Polymerase-1 - metabolism | Apoptosis Inducing Factor - genetics | Mice, Knockout | Stroke - enzymology | Deoxyribonucleases - genetics | Animals | Intramolecular Oxidoreductases - genetics | Neurons - enzymology | Mice | HeLa Cells | Mutation | Glutamic Acid - toxicity | DNA Cleavage | Glutamic Acid - chemistry | Polymerase chain reaction | DNA damage | Cells | Cell death | Deoxyribonucleic acid | Activation | Nuclease | Inhibition | Damage accumulation | Nuclei | Diseases
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 02/2019, Volume 131, pp. 184 - 196
In inflamed tissues or during ischemia-reperfusion episodes, activated macrophages produce large amounts of reactive species and are, thus, exposed to the... 
Hydrogen peroxide | Cell death | Lipopolysaccharide | Parthanatos | Macrophage | Necrosis | Apoptosis | Warburg effect | OXIDATIVE-STRESS | PEROXYNITRITE | MITOCHONDRIAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | PEROXIREDOXIN | TRANSCRIPTION | CANCER | CELL-DEATH | THIOREDOXIN | ENDOCRINOLOGY & METABOLISM | INDUCED CYTOTOXICITY
Journal Article
Movement disorders : official journal of the Movement Disorder Society, ISSN 0885-3185, 1/2013, Volume 28, Issue 1, pp. 51 - 60
The defining anatomical feature of Parkinson’s disease (PD) is the degeneration of substantia nigra pars compacta (SNc) neurons, resulting in striatal dopamine... 
dopamine receptors | LRRK2 | synaptic plasticity | NMDA receptors | Parthanatos
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 11/2014, Volume 92, Issue 1, pp. 157 - 163
Poly(ADP-ribosylation) results from the conversion of NAD into ADP-ribose and the following addition of ADP-ribose units to form polymers, further bound to... 
PAR | PARP | Necroptosis | Autophagy | Parthanatos | Apoptosis | POLYMERASE 3 PARP3 | RIP KINASES | APOPTOSIS-INDUCING FACTOR | OXIDATIVE STRESS | MITOCHONDRIAL | DNA-DAMAGE | CROSS-TALK | ROLES | PHARMACOLOGY & PHARMACY | TANKYRASE | Signal Transduction - physiology | Poly Adenosine Diphosphate Ribose - metabolism | Animals | Cell Death - physiology | Humans | Cell death | Sugars | Monosaccharides
Journal Article