X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (50882) 50882
Newsletter (2272) 2272
Book Chapter (211) 211
Newspaper Article (189) 189
Dissertation (100) 100
Conference Proceeding (75) 75
Magazine Article (61) 61
Publication (37) 37
Reference (12) 12
Government Document (11) 11
Book / eBook (5) 5
Paper (5) 5
Transcript (5) 5
Web Resource (3) 3
Book Review (2) 2
Trade Publication Article (2) 2
Data Set (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
phenylalanine (19945) 19945
humans (16952) 16952
animals (12459) 12459
index medicus (8989) 8989
biochemistry & molecular biology (7794) 7794
male (7184) 7184
phenylalanine - metabolism (6820) 6820
female (5809) 5809
n-formylmethionine leucyl-phenylalanine - pharmacology (5582) 5582
kinetics (5316) 5316
rats (5015) 5015
amino acids (4413) 4413
research (4077) 4077
analysis (3672) 3672
phenylalanine - analogs & derivatives (3405) 3405
tyrosine (3327) 3327
adult (3277) 3277
neutrophils - drug effects (3259) 3259
proteins (3163) 3163
phenylalanine - chemistry (3160) 3160
phenylalanine - pharmacology (3060) 3060
phenylalanine ammonia-lyase (3032) 3032
phenylalanine - blood (3017) 3017
molecular sequence data (2909) 2909
amino acid sequence (2804) 2804
enzymes (2775) 2775
in vitro techniques (2749) 2749
mice (2721) 2721
mutation (2594) 2594
phenylketonuria (2527) 2527
neutrophils - metabolism (2475) 2475
plant sciences (2422) 2422
binding sites (2348) 2348
metabolism (2291) 2291
physiological aspects (2269) 2269
time factors (2139) 2139
models, molecular (2097) 2097
carbon isotopes (2068) 2068
cell biology (1938) 1938
chemistry (1923) 1923
pharmacology & pharmacy (1923) 1923
tryptophan (1903) 1903
expression (1900) 1900
peptides (1864) 1864
biosynthesis (1858) 1858
protein binding (1725) 1725
hydrogen-ion concentration (1675) 1675
research article (1674) 1674
biophysics (1661) 1661
protein biosynthesis (1649) 1649
chemistry, multidisciplinary (1646) 1646
neutrophils - physiology (1644) 1644
middle aged (1643) 1643
amino acids - metabolism (1617) 1617
base sequence (1566) 1566
protein conformation (1539) 1539
biotechnology & applied microbiology (1534) 1534
cells, cultured (1481) 1481
life sciences (1473) 1473
amino-acids (1472) 1472
child (1455) 1455
immunology (1451) 1451
tyrosine - metabolism (1442) 1442
structure-activity relationship (1437) 1437
activation (1394) 1394
ribosomes - metabolism (1390) 1390
protein (1382) 1382
tritium (1374) 1374
ammonia (1359) 1359
dose-response relationship, drug (1346) 1346
gene expression (1340) 1340
infant, newborn (1340) 1340
tetradecanoylphorbol acetate - pharmacology (1337) 1337
leucine (1335) 1335
genetics & heredity (1333) 1333
genes (1326) 1326
phenylalanine - genetics (1274) 1274
escherichia-coli (1257) 1257
phenylalanin (1247) 1247
adolescent (1218) 1218
temperature (1216) 1216
multidisciplinary sciences (1212) 1212
endocrinology & metabolism (1205) 1205
escherichia coli - metabolism (1196) 1196
superoxides - metabolism (1194) 1194
chemistry, physical (1186) 1186
crystal-structure (1169) 1169
l-phenylalanine (1157) 1157
cells (1155) 1155
metabolites (1154) 1154
food science & technology (1150) 1150
microbiology (1150) 1150
escherichia coli (1142) 1142
mutagenesis, site-directed (1141) 1141
biochemistry (1139) 1139
rabbits (1119) 1119
binding (1106) 1106
phosphorylation (1103) 1103
cell line (1089) 1089
catalysis (1085) 1085
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (51157) 51157
German (847) 847
Japanese (682) 682
Russian (511) 511
French (464) 464
Chinese (390) 390
Spanish (116) 116
Italian (108) 108
Polish (76) 76
Portuguese (61) 61
Czech (49) 49
Korean (28) 28
Dutch (16) 16
Ukrainian (16) 16
Swedish (12) 12
Hungarian (10) 10
Danish (9) 9
Romanian (9) 9
Croatian (6) 6
Slovak (6) 6
Persian (5) 5
Bulgarian (3) 3
Finnish (3) 3
Lithuanian (3) 3
Norwegian (3) 3
Arabic (2) 2
Hebrew (2) 2
Icelandic (2) 2
Slovenian (2) 2
Estonian (1) 1
Latvian (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
American journal of human genetics, ISSN 0002-9297, 2008, Volume 83, Issue 1, pp. 5 - 17
A significant share of patients with phenylalanine hydroxylase (PAH) deficiency benefits from pharmacological doses of tetrahydrobiopterin (BH 4), the natural... 
WILD-TYPE | EXPRESSION ANALYSIS | SUBSTRATE-BINDING | MILD PHENYLKETONURIA | STRUCTURAL BASIS | ACTIVE-SITE | GENETICS & HEREDITY | CATALYTIC DOMAIN | PKU MUTATIONS | HUMAN PHENYLALANINE-HYDROXYLASE | MISSENSE MUTATIONS | Phenylalanine Hydroxylase - genetics | Phenylketonurias - genetics | Allosteric Regulation | Humans | Luminescence | Phenylalanine Hydroxylase - deficiency | Male | Mutation, Missense | Biopterin - analogs & derivatives | Recombinant Fusion Proteins - metabolism | Biopterin - administration & dosage | Protein Subunits - metabolism | Biopterin - therapeutic use | Computer Simulation | Protein Denaturation | Female | Binding Sites | Dimerization | Endopeptidase K - pharmacology | Infant, Newborn | Phenylalanine Hydroxylase - metabolism | Amino Acid Sequence | Motion | Phenylketonurias - enzymology | Catalytic Domain | Phenylalanine - metabolism | Protein Structure, Secondary | Administration, Oral | Enzyme Stability | Models, Molecular | Protein Structure, Tertiary - genetics | Hot Temperature | Phenylalanine Hydroxylase - analysis | Recombinant Fusion Proteins - chemistry | Static Electricity | Protein Folding | Hydrolysis | Hydrogen Bonding | Amino Acid Metabolism, Inborn Errors | Hydrophobic and Hydrophilic Interactions | Phenylalanine - blood | Protein Conformation | Protein Subunits - chemistry | Kinetics | Phenylalanine Hydroxylase - chemistry | Amino Acid Substitution | Causes of | Phenylketonuria | Genetic aspects | Research | Gene mutations | Protein folding
Journal Article
Journal Article
Biochemistry, ISSN 0006-2960, 04/2011, Volume 50, Issue 14, pp. 2919 - 2930
Journal Article