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Journal Article
Journal Article
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2016, Volume 75, Issue 3, pp. 494 - 503.e6
Journal Article
Drugs, ISSN 0012-6667, 9/2017, Volume 77, Issue 13, pp. 1389 - 1397
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 09/2013, Volume 72, Issue 9, pp. 1475 - 1480
Journal Article
Pulmonary Pharmacology & Therapeutics, ISSN 1094-5539, 2010, Volume 23, Issue 4, pp. 235 - 256
Abstract After more than two decades of research into phosphodiesterase 4 (PDE4) inhibitors, roflumilast... 
Medical Education | Pulmonary/Respiratory | Phosphodiesterase 4 | Inflammation | Roflumilast | Oral therapy | COPD | Preclinical pharmacology | SMOKE-INDUCED EMPHYSEMA | OXIDATIVE STRESS | FIBROBLAST-MEDIATED CONTRACTION | NECROSIS-FACTOR-ALPHA | ADHESION MOLECULES | PDE4 INHIBITORS | TRANSMEMBRANE CONDUCTANCE REGULATOR | RESPIRATORY SYSTEM | EPIDERMAL-GROWTH-FACTOR | PHARMACOLOGY & PHARMACY | ENDOTHELIAL CELL-INTERACTIONS | CIGARETTE-SMOKE | Phosphodiesterase Inhibitors - therapeutic use | Phosphodiesterase Inhibitors - adverse effects | Administration, Oral | Humans | Aminopyridines - adverse effects | Phosphodiesterase Inhibitors - pharmacology | Pulmonary Disease, Chronic Obstructive - physiopathology | Cyclopropanes - adverse effects | Inflammation - etiology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Cyclopropanes - therapeutic use | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Benzamides - therapeutic use | Aminopyridines - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Inflammation - drug therapy | Aminopyridines - pharmacology | Phosphodiesterase 4 Inhibitors | Benzamides - pharmacology | Drug Evaluation, Preclinical | Benzamides - adverse effects | Cyclopropanes - pharmacology | Pulmonary Disease, Chronic Obstructive - drug therapy | Lung diseases, Obstructive | Isoenzymes | Comorbidity | Respiratory agents | Pharmacology | T cells | Macrophages | Pulmonary hypertension | Endothelium | Metabolites | Universities and colleges | Smoking
Journal Article
Journal Article