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Lipids, ISSN 0024-4201, 06/2019, Volume 54, Issue 6-7, pp. 369 - 379
Dysregulated hepatic gluconeogenesis is a hallmark of insulin resistance and type 2 diabetes mellitus (T2DM). Although existing drugs have been proven to... 
Rosiglitazone | Conjugated linoleic acid | Glucose‐6‐phosphatase | Phosphoenolpyruvate carboxykinase | Gluconeogenesis | ACTIVATION | LIPID-METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | DAIRY-COWS | NUTRITION & DIETETICS | PEPCK GENE-EXPRESSION | INSULIN-RESISTANCE | LIVER | ISOMERS | PPAR-GAMMA | Glucose-6-phosphatase
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2015, Volume 60, Issue 2, pp. 195 - 207
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, p. e0179988
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 07/2010, Volume 120, Issue 7, pp. 2355 - 2369
Metformin is widely used to treat hyperglycemia in individuals with type 2 diabetes. Recently the LKB1/AMP-activated protein kinase (LKB1/AMPK) pathway was... 
MEDICINE, RESEARCH & EXPERIMENTAL | RESPIRATORY-CHAIN | SKELETAL-MUSCLE | PHOSPHOENOLPYRUVATE CARBOXYKINASE | ACTIVATED PROTEIN-KINASE | GLUCOKINASE TRANSLOCATION | GLUCOSE-METABOLISM | COACTIVATOR TORC2 | AICA RIBOSIDE | UPSTREAM KINASE | ISOLATED RAT HEPATOCYTES | Glucose-6-Phosphatase - genetics | Hypoglycemic Agents - metabolism | Diabetes Mellitus, Type 2 - genetics | Gluconeogenesis - drug effects | Diabetes Mellitus, Type 2 - metabolism | Hepatocytes - metabolism | Metformin - metabolism | AMP-Activated Protein Kinases | Hyperglycemia - genetics | Liver - drug effects | Protein-Serine-Threonine Kinases - metabolism | Liver - metabolism | Metformin - pharmacology | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Glucose - genetics | Glucose - pharmacology | Glucose-6-Phosphatase - metabolism | Hypoglycemic Agents - pharmacology | Mice, Knockout | Hyperglycemia - metabolism | Phosphoenolpyruvate Carboxykinase (ATP) - genetics | Up-Regulation - drug effects | Animals | Gluconeogenesis - genetics | Glucose-6-Phosphatase - biosynthesis | Phosphoenolpyruvate Carboxykinase (ATP) - metabolism | Glucose - metabolism | Mice | Protein-Serine-Threonine Kinases - pharmacology | Type 2 diabetes | Control | Usage | Genetic aspects | Research | Metformin | Gene expression | Drug therapy | Health aspects | Gluconeogenesis | Up-Regulation | Glucose-6-Phosphatase | gluconeogenesis, animal models | Liver | Protein-Serine-Threonine Kinases | Glucose | LKB1 | Life Sciences | Hypoglycemic Agents | Phosphoenolpyruvate Carboxykinase (ATP) | Human health and pathology | Hyperglycemia | Hepatocytes | AMPK | Endocrinology and metabolism | Diabetes Mellitus, Type 2
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2012, Volume 287, Issue 44, pp. 37340 - 37351
Chronic hepatitis C virus (HCV) infection greatly increases the risk for type 2 diabetes and nonalcoholic steatohepatitis; however, the pathogenic mechanisms... 
DIABETES-MELLITUS | LIPID-ACCUMULATION | GLUCONEOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | RESISTANCE | INFECTION | SERINE PHOSPHORYLATION | INSULIN-RECEPTOR SUBSTRATE-1 | CCAAT/ENHANCER-BINDING-PROTEIN | GLUCOSE-PRODUCTION | Glucose-6-Phosphatase - genetics | Insulin - physiology | Humans | Phosphoenolpyruvate Carboxykinase (GTP) - metabolism | Secretory Vesicles - metabolism | Hepacivirus - genetics | Diabetes Mellitus, Type 2 - virology | Phosphoenolpyruvate Carboxykinase (GTP) - genetics | Luciferases - genetics | Forkhead Transcription Factors - metabolism | Fatty Liver - enzymology | Hepacivirus - physiology | Lipid Metabolism - genetics | Genes, Reporter | Genome, Viral | Promoter Regions, Genetic | Signal Transduction | Fatty Liver - virology | CCAAT-Enhancer-Binding Protein-beta - genetics | Enzyme Induction | Rats | Forkhead Transcription Factors - genetics | CCAAT-Enhancer-Binding Protein-beta - metabolism | Glucose-6-Phosphatase - metabolism | Viral Nonstructural Proteins - physiology | CCAAT-Enhancer-Binding Protein-beta - physiology | Animals | Gluconeogenesis - genetics | Virus Replication | Cyclic AMP Response Element-Binding Protein - metabolism | Cell Line, Tumor | Glucose - metabolism | Forkhead Box Protein O1 | Luciferases - biosynthesis | Molecular Bases of Disease | Obesity | Liver Metabolism | Diabetes | NASH | Insulin | Gluconeogenesis
Journal Article