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Journal of Molecular Biology, ISSN 0022-2836, 12/2008, Volume 384, Issue 1, pp. 120 - 136
The alkaline phosphatase superfamily comprises a large number of hydrolytic metalloenzymes such as phosphatases and sulfatases. We have characterised a new... 
phosphonate monoester hydrolase | double-displacement mechanism | phosphodiesterase | alkaline phosphatase superfamily | formylglycine | POSTTRANSLATIONAL FORMATION | CATALYTIC PROMISCUITY | ACTIVE-SITE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BURKHOLDERIA CARYOPHILLI PG2982 | ESCHERICHIA-COLI | HUMAN ARYLSULFATASE | PHOSPHOGLYCERATE MUTASE | ESTER HYDROLYSIS | SULFUR PROTEIN ATSB | SITE-SPECIFIC MUTAGENESIS | Glycine - analogs & derivatives | Glycine - metabolism | Hydrolysis - drug effects | Alkaline Phosphatase - metabolism | Crystallography, X-Ray | Rhizobium leguminosarum - enzymology | Mutagenesis - drug effects | Alkaline Phosphatase - chemistry | Protein Structure, Quaternary | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Catalysis | Binding Sites | Phosphoric Diester Hydrolases - metabolism | Protein Structure, Secondary | Models, Molecular | Mutant Proteins - metabolism | Static Electricity | Protein Folding | Phosphoric Diester Hydrolases - chemistry | Substrate Specificity - drug effects | Mutant Proteins - chemistry | Structural Homology, Protein | Kinetics | Evolution, Molecular | Metals - pharmacology | Post-translational modification | Legumes | Enzymes | Cysteine | Phosphatases | Phosphonates | Crystals | Nucleotides | Mimosaceae | Polyols | Nature conservation | Hydrolysis | Beans | Polyethylene glycol | Analysis | Structure | Mass spectrometry | Index Medicus
Journal Article
Journal Article
ACS Chemical Biology, ISSN 1554-8929, 12/2014, Volume 9, Issue 12, pp. 2875 - 2882
Journal Article
Journal Article
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 10/2015, Volume 56, Issue 41, pp. 5619 - 5622
Fluorophosphonates represent powerful probes for the identification and analysis of active serine hydrolases in activity based protein profiling. Although... 
Arylphosphonofluoridates | Monoesterification | DAST fluorination | Pyrophosphonates | Activity based probes | ACID | ACTIVITY-BASED PROTEOMICS | SPECIFICITY | ANALOGS | CHEMISTRY, ORGANIC | SERINE HYDROLASES | PHOSPHONATE | INHIBITION | ENZYME | ESTERS | MONOESTERS | Enzymes | Hydrolases | Analysis
Journal Article