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11/2012
Transgenic manipulation of exogenous and endogenous gene expression in human embryonic stem cells (hESCs) is a powerful approach to decipher the genetic... 
R4-Integrase | 0541 | human embryonic stem cell | piggyBac
Dissertation
NATURE, ISSN 0028-0836, 10/2011, Volume 478, Issue 7369, pp. 391 - 391
Human induced pluripotent stem cells (iPSCs) represent a unique opportunity for regenerative medicine because they offer the prospect of generating unlimited... 
COMPLEX | MULTIDISCIPLINARY SCIENCES | PIGGYBAC TRANSPOSON | GENERATION | INDUCTION | ZINC-FINGER NUCLEASES | EFFICIENT | GENOME | LINES
Journal Article
Oncotarget, ISSN 1949-2553, 07/2019, Volume 10, Issue 42, p. 4253
Journal Article
Journal Article
Cancers, ISSN 2072-6694, 09/2019, Volume 11, Issue 9, p. 1335
The most common brain tumours, gliomas, have significant morbidity. Detailed biological and genetic understanding of these tumours is needed in order to devise... 
transposon | CRISPR | glioma | cancer | mouse model | piggyBac
Journal Article
Journal of Virological Methods, ISSN 0166-0934, 12/2019, Volume 274, p. 113727
CD163 is a cellular receptor for (PRRSV). Transgenic expression of CD163 can predispose a variety of PRRSV non-permissive cells to PRRSV infection. These... 
CD163 | Susceptibility | PiggyBac | PRRSV | 3D4/21/CD163
Journal Article
Nature Biotechnology, ISSN 1087-0156, 09/2018, Volume 36, Issue 8, pp. 765 - 771
Journal Article
Journal of molecular biology, ISSN 0022-2836, 9/2017, Volume 429, Issue 18, pp. 2780 - 2789
The development of haploid mammalian cell lines, coupled to next generation sequencing, has recently facilitated forward genetic screenings in mammals. For... 
piggyBac transposon | genetic screenings | haploid mammalian cells | Genetrap | RNAseq
Journal Article
Biology of Reproduction, ISSN 0006-3363, 2014, Volume 90, Issue 5, pp. 93 - 93
ABSTRACT The process of transgenesis involves the introduction of a foreign gene, the transgene, into the genome of an animal. Gene transfer by pronuclear... 
transgenesis | pmGENIE-3 | piggyBac | transposase | pig
Journal Article
Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7562, pp. 561 - 567
Journal Article
Genes & Diseases, ISSN 2352-3042, 03/2015, Volume 2, Issue 1, pp. 96 - 105
Sustained, high level transgene expression in mammalian cells is desired in many cases for studying gene functions. Traditionally, stable transgene expression... 
piggyBac transposon | Transposition | piggyBac transposase | Stable transgene expression | Retroviral vectors | Mesenchymal stem cells | PiggyBac transposase | PiggyBac transposon
Journal Article
Expert Opinion on Biological Therapy, ISSN 1471-2598, 07/2012, Volume 12, Issue 7, pp. 841 - 858
Journal Article