Critical Care Medicine, ISSN 0090-3493, 05/2017, Volume 45, Issue 5, pp. e470 - e478
Journal Article
Critical Care Medicine, ISSN 0090-3493, 02/2018, Volume 46, Issue 2, pp. 333 - 335
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 10/2011, Volume 50, Issue 10, pp. 637 - 664
The exposure-response relationship of anti-infective agents at the site of infection is currently being re-examined. Epithelial lining fluid (ELF) has been...
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Iclaprim | Linezolid | Levofloxacin | Clarithromycin | Cefepime | Gentamicin | Azithromycin | Roxithromycin | Cefdinir | Moxifloxacin | Vancomycin | Teicoplanin | Ceftobiprole | Antibacterials | Amoxicillinclavulanic-acid | Cefditoren | Cefpodoxime-proxetil | Pulmonary-lavage | Meropenem | Interstitial-fluid | Piperacillintazobactam | Cefaclor | Ceftazidime | Netilmicin | Cefpirome | Dirithromycin | Telithromycin | Pharmacology | Erythromycin | Ertapenem | Modithromycin | Cethromycin | Telavancin | Ceftibuten | Tobramycin | Biapenem | Ciprofloxacin | Oritavancin | Pharmacokinetics | Tigecycline | Cefuroxime-axetil | COMMUNITY-ACQUIRED PNEUMONIA | VENTILATOR-ASSOCIATED PNEUMONIA | SEVERE NOSOCOMIAL PNEUMONIA | KETOLIDE ANTIMICROBIAL AGENT | HEALTHY ADULT SUBJECTS | PHARMACOLOGY & PHARMACY | MONTE-CARLO-SIMULATION | RESISTANT STREPTOCOCCUS-PNEUMONIAE | STEADY-STATE PLASMA | CRITICALLY-ILL PATIENTS | IN-VITRO ACTIVITY | Epithelium - metabolism | Humans | Bronchoalveolar Lavage Fluid - microbiology | Microbial Sensitivity Tests | Tissue Distribution | Models, Biological | Body Fluid Compartments - metabolism | Anti-Bacterial Agents - pharmacokinetics | Anti-Bacterial Agents - pharmacology | Lung - metabolism | Bronchoalveolar Lavage Fluid - chemistry | Macrophages, Alveolar - metabolism | Anti-Bacterial Agents - administration & dosage | Monte Carlo Method
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Iclaprim | Linezolid | Levofloxacin | Clarithromycin | Cefepime | Gentamicin | Azithromycin | Roxithromycin | Cefdinir | Moxifloxacin | Vancomycin | Teicoplanin | Ceftobiprole | Antibacterials | Amoxicillinclavulanic-acid | Cefditoren | Cefpodoxime-proxetil | Pulmonary-lavage | Meropenem | Interstitial-fluid | Piperacillintazobactam | Cefaclor | Ceftazidime | Netilmicin | Cefpirome | Dirithromycin | Telithromycin | Pharmacology | Erythromycin | Ertapenem | Modithromycin | Cethromycin | Telavancin | Ceftibuten | Tobramycin | Biapenem | Ciprofloxacin | Oritavancin | Pharmacokinetics | Tigecycline | Cefuroxime-axetil | COMMUNITY-ACQUIRED PNEUMONIA | VENTILATOR-ASSOCIATED PNEUMONIA | SEVERE NOSOCOMIAL PNEUMONIA | KETOLIDE ANTIMICROBIAL AGENT | HEALTHY ADULT SUBJECTS | PHARMACOLOGY & PHARMACY | MONTE-CARLO-SIMULATION | RESISTANT STREPTOCOCCUS-PNEUMONIAE | STEADY-STATE PLASMA | CRITICALLY-ILL PATIENTS | IN-VITRO ACTIVITY | Epithelium - metabolism | Humans | Bronchoalveolar Lavage Fluid - microbiology | Microbial Sensitivity Tests | Tissue Distribution | Models, Biological | Body Fluid Compartments - metabolism | Anti-Bacterial Agents - pharmacokinetics | Anti-Bacterial Agents - pharmacology | Lung - metabolism | Bronchoalveolar Lavage Fluid - chemistry | Macrophages, Alveolar - metabolism | Anti-Bacterial Agents - administration & dosage | Monte Carlo Method
Journal Article
Drugs, ISSN 0012-6667, 4/2012, Volume 72, Issue 6, pp. e17 - e32
Intra-abdominal infection (IAI) is a complex disease entity in which different aspects must be balanced in order to select the proper antimicrobial regimen and...
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Fluoroquinolones | Linezolid | Doripenem | Daptomycin | Intra-abdominal-infections | Aminoglycosides | Moxifloxacin | Quinupristindalfopristin | Amoxicillinclavulanic-acid | Imidazoles | Cephalosporins | Imipenemcilastatin | Meropenem | Carbapenems | Piperacillintazobactam | Tigecycline | Glycopeptides | SECONDARY PERITONITIS | RISK-FACTORS | INTENSIVE-CARE-UNIT | MULTIDRUG-RESISTANT BACTERIA | ESCHERICHIA-COLI | PHARMACOLOGY & PHARMACY | POSTOPERATIVE PERITONITIS | TOXICOLOGY | DISEASES SOCIETY | INVASIVE CANDIDIASIS | ANTIBIOTIC-THERAPY | SEVERE SEPSIS | Severity of Illness Index | Anti-Infective Agents - therapeutic use | Intraabdominal Infections - drug therapy | Humans | Risk Factors | Prevention | Usage | Abscess | Anti-infective agents | Dosage and administration | Health aspects | Abdomen | Therapy In Practice
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Fluoroquinolones | Linezolid | Doripenem | Daptomycin | Intra-abdominal-infections | Aminoglycosides | Moxifloxacin | Quinupristindalfopristin | Amoxicillinclavulanic-acid | Imidazoles | Cephalosporins | Imipenemcilastatin | Meropenem | Carbapenems | Piperacillintazobactam | Tigecycline | Glycopeptides | SECONDARY PERITONITIS | RISK-FACTORS | INTENSIVE-CARE-UNIT | MULTIDRUG-RESISTANT BACTERIA | ESCHERICHIA-COLI | PHARMACOLOGY & PHARMACY | POSTOPERATIVE PERITONITIS | TOXICOLOGY | DISEASES SOCIETY | INVASIVE CANDIDIASIS | ANTIBIOTIC-THERAPY | SEVERE SEPSIS | Severity of Illness Index | Anti-Infective Agents - therapeutic use | Intraabdominal Infections - drug therapy | Humans | Risk Factors | Prevention | Usage | Abscess | Anti-infective agents | Dosage and administration | Health aspects | Abdomen | Therapy In Practice
Journal Article
Hospital Pharmacy, ISSN 0018-5787, 3/2017, Volume 52, Issue 3, pp. 221 - 228
Objectives The compatibility of vancomycin with existing and novel β-lactam/β-lactamase inhibitors at clinically relevant concentrations in 5% dextrose in...
Ceftolozane-tazobactam | Vancomycin | Compatibility | Piperacillintazobactam | Ceftazidime-avibactam | Dextrose | dextrose | ceftolozane-tazobactam | vancomycin | ceftazidime-avibactam | Original | compatibility | piperacillin-tazobactam
Ceftolozane-tazobactam | Vancomycin | Compatibility | Piperacillintazobactam | Ceftazidime-avibactam | Dextrose | dextrose | ceftolozane-tazobactam | vancomycin | ceftazidime-avibactam | Original | compatibility | piperacillin-tazobactam
Journal Article
Journal of Biomaterials Science, Polymer Edition, ISSN 0920-5063, 05/2013, Volume 24, Issue 7, pp. 807 - 819
The aim of this study is to prepare a novel wound dressing material which provides burst release of an antibiotic in combination with sustained release of...
chitosan | sequential release | EGF | cell culture | semi-IPN hydrogels | piperacillin-tazobactam | MATERIALS SCIENCE, BIOMATERIALS | POLYMER SCIENCE | PIPERACILLIN-TAZOBACTAM | ENGINEERING, BIOMEDICAL | SWELLING BEHAVIOR | DELIVERY | piperacillintazobactam | CHITIN | ACRYLIC-ACID | Cell Line | Wounds and Injuries - surgery | Bandages | Biocompatible Materials - chemistry | Piperacillin - chemistry | Biocompatible Materials - pharmacology | Acrylic Resins - chemistry | Penicillanic Acid - chemistry | Animals | Chitosan - chemistry | Anti-Bacterial Agents - chemistry | Epidermal Growth Factor - chemistry | Water - chemistry | Mice | Kinetics | Hydrogels - chemistry | Penicillanic Acid - analogs & derivatives
chitosan | sequential release | EGF | cell culture | semi-IPN hydrogels | piperacillin-tazobactam | MATERIALS SCIENCE, BIOMATERIALS | POLYMER SCIENCE | PIPERACILLIN-TAZOBACTAM | ENGINEERING, BIOMEDICAL | SWELLING BEHAVIOR | DELIVERY | piperacillintazobactam | CHITIN | ACRYLIC-ACID | Cell Line | Wounds and Injuries - surgery | Bandages | Biocompatible Materials - chemistry | Piperacillin - chemistry | Biocompatible Materials - pharmacology | Acrylic Resins - chemistry | Penicillanic Acid - chemistry | Animals | Chitosan - chemistry | Anti-Bacterial Agents - chemistry | Epidermal Growth Factor - chemistry | Water - chemistry | Mice | Kinetics | Hydrogels - chemistry | Penicillanic Acid - analogs & derivatives
Journal Article
TURKISH JOURNAL OF HEMATOLOGY, ISSN 1300-7777, 12/2018, Volume 35, Issue 4, pp. 290 - 295
Objective: We aimed to find the incidence and risk factors of hematologic adverse effects of piperacillin-tazobactam (TZP). Materials and Methods: Adult...
INFECTIONS | Leukopenia | Piperacillin-tazobactam | Adverse effects | HEMATOLOGY | Eosinophilia | Neutropenia | Humans | Middle Aged | Risk Factors | Female | Leukopenia - drug therapy | Male | Eosinophilia - drug therapy | Piperacillin, Tazobactam Drug Combination - adverse effects | Neutropenia - drug therapy | Statistical analysis | Comorbidity | Anemia | Systematic review | Multivariate analysis | Patients | Risk factors | Fever | Antibiotics | Hemoglobin | Data collection | Bone marrow | Nosocomial infections | Drug dosages | Brief Report | Piperacillintazobactam
INFECTIONS | Leukopenia | Piperacillin-tazobactam | Adverse effects | HEMATOLOGY | Eosinophilia | Neutropenia | Humans | Middle Aged | Risk Factors | Female | Leukopenia - drug therapy | Male | Eosinophilia - drug therapy | Piperacillin, Tazobactam Drug Combination - adverse effects | Neutropenia - drug therapy | Statistical analysis | Comorbidity | Anemia | Systematic review | Multivariate analysis | Patients | Risk factors | Fever | Antibiotics | Hemoglobin | Data collection | Bone marrow | Nosocomial infections | Drug dosages | Brief Report | Piperacillintazobactam
Journal Article
Drugs, ISSN 0012-6667, 2010, Volume 70, Issue 15, pp. 1927 - 1944
Ventilator-associated pneumonia (YAP) affects 10-20% of mechanically ventilated patients and is associated with increased morbidity and mortality and high...
Linezolid | Levofloxacin | Selective-gastrointestinal-decontamination | Amikacin | Cefepime | Cefotaxime | Gentamicin | Vancomycin | Ertapenem | Cefuroxime | Amoxicillinclavulanic-acid | Imipenemcilastatin | Nosocomial-pneumonia | Meropenem | Ciprofloxacin | Piperacillintazobactam | Ceftazidime | C-REACTIVE PROTEIN | RANDOMIZED CONTROLLED-TRIALS | COMMUNITY-ACQUIRED PNEUMONIA | GRAM-NEGATIVE BACTERIA | INTENSIVE-CARE-UNIT | COATED ENDOTRACHEAL-TUBES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | ADULT ICU PATIENTS | SUBGLOTTIC SECRETION DRAINAGE | REQUIRING MECHANICAL VENTILATION | ANTIBIOTIC-THERAPY | Humans | Biomarkers - analysis | Clinical Protocols | Pneumonia, Ventilator-Associated - prevention & control | Anti-Infective Agents - therapeutic use | Pneumonia, Ventilator-Associated - etiology | Early Diagnosis | Cross Infection - drug therapy | Pneumonia, Ventilator-Associated - diagnosis | Pneumonia, Ventilator-Associated - drug therapy
Linezolid | Levofloxacin | Selective-gastrointestinal-decontamination | Amikacin | Cefepime | Cefotaxime | Gentamicin | Vancomycin | Ertapenem | Cefuroxime | Amoxicillinclavulanic-acid | Imipenemcilastatin | Nosocomial-pneumonia | Meropenem | Ciprofloxacin | Piperacillintazobactam | Ceftazidime | C-REACTIVE PROTEIN | RANDOMIZED CONTROLLED-TRIALS | COMMUNITY-ACQUIRED PNEUMONIA | GRAM-NEGATIVE BACTERIA | INTENSIVE-CARE-UNIT | COATED ENDOTRACHEAL-TUBES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | ADULT ICU PATIENTS | SUBGLOTTIC SECRETION DRAINAGE | REQUIRING MECHANICAL VENTILATION | ANTIBIOTIC-THERAPY | Humans | Biomarkers - analysis | Clinical Protocols | Pneumonia, Ventilator-Associated - prevention & control | Anti-Infective Agents - therapeutic use | Pneumonia, Ventilator-Associated - etiology | Early Diagnosis | Cross Infection - drug therapy | Pneumonia, Ventilator-Associated - diagnosis | Pneumonia, Ventilator-Associated - drug therapy
Journal Article
Drugs, ISSN 0012-6667, 2010, Volume 70, Issue 7, pp. 841 - 858
Anaerobic bacteria are the predominant indigenous flora of humans and, as a result, play an important role in infections, some of which are serious with a high...
Carbapenems, therapeutic use | Piperacillintazobactam, therapeutic use | Tigecycline, therapeutic use | Metronidazole, therapeutic use | Clindamycin, therapeutic use | Anaerobic-infections, treatment | Cephamycins, therapeutic use | Moxifloxacin, therapeutic use | ANTIMICROBIAL SUSCEPTIBILITY | PENICILLIN-BINDING PROTEINS | ANTIBIOTIC-RESISTANCE | FLUOROQUINOLONE RESISTANCE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | NITROIMIDAZOLE RESISTANCE | METRONIDAZOLE RESISTANCE | BACTEROIDES-FRAGILIS GROUP | CARBAPENEMASE GENE CFIA | IN-VITRO ACTIVITY | CLOSTRIDIUM-DIFFICILE | Gram-Negative Anaerobic Bacteria - isolation & purification | Humans | Gram-Negative Bacterial Infections - drug therapy | Gram-Positive Bacterial Infections - epidemiology | Gram-Negative Bacterial Infections - microbiology | Anti-Bacterial Agents - therapeutic use | Bacteria, Anaerobic - isolation & purification | Animals | Gram-Positive Bacterial Infections - microbiology | Gram-Negative Bacterial Infections - epidemiology | Anti-Bacterial Agents - adverse effects | Bacteria, Anaerobic - drug effects | Gram-Negative Anaerobic Bacteria - drug effects | Gram-Positive Bacterial Infections - drug therapy | Anti-Bacterial Agents - administration & dosage | Drug Resistance, Multiple, Bacterial - drug effects
Carbapenems, therapeutic use | Piperacillintazobactam, therapeutic use | Tigecycline, therapeutic use | Metronidazole, therapeutic use | Clindamycin, therapeutic use | Anaerobic-infections, treatment | Cephamycins, therapeutic use | Moxifloxacin, therapeutic use | ANTIMICROBIAL SUSCEPTIBILITY | PENICILLIN-BINDING PROTEINS | ANTIBIOTIC-RESISTANCE | FLUOROQUINOLONE RESISTANCE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | NITROIMIDAZOLE RESISTANCE | METRONIDAZOLE RESISTANCE | BACTEROIDES-FRAGILIS GROUP | CARBAPENEMASE GENE CFIA | IN-VITRO ACTIVITY | CLOSTRIDIUM-DIFFICILE | Gram-Negative Anaerobic Bacteria - isolation & purification | Humans | Gram-Negative Bacterial Infections - drug therapy | Gram-Positive Bacterial Infections - epidemiology | Gram-Negative Bacterial Infections - microbiology | Anti-Bacterial Agents - therapeutic use | Bacteria, Anaerobic - isolation & purification | Animals | Gram-Positive Bacterial Infections - microbiology | Gram-Negative Bacterial Infections - epidemiology | Anti-Bacterial Agents - adverse effects | Bacteria, Anaerobic - drug effects | Gram-Negative Anaerobic Bacteria - drug effects | Gram-Positive Bacterial Infections - drug therapy | Anti-Bacterial Agents - administration & dosage | Drug Resistance, Multiple, Bacterial - drug effects
Journal Article
Journal of Perinatology, ISSN 0743-8346, 07/2013, Volume 33, Issue 7, pp. 529 - 532
OBJECTIVE: We changed from ampicillin and gentamicin (AG) to piperacillin-tazobactam (PT) for routine treatment of suspected early-onset sepsis. The rationale...
gentamicin | necrotizing enterocolitis | ampicillin | piperacillintazobactam | diaper rash | IN-VITRO | EARLY-ONSET SEPSIS | ANTIBIOTIC EXPOSURE | RISK | PEDIATRICS | piperacillin-tazobactam | OBSTETRICS & GYNECOLOGY | Infant, Very Low Birth Weight | Humans | Male | Treatment Outcome | Ampicillin - administration & dosage | Gentamicins - administration & dosage | Infant, Premature, Diseases - drug therapy | Sepsis - drug therapy | Diaper Rash - prevention & control | Apgar Score | Infant, Premature | Penicillanic Acid - therapeutic use | Female | Retrospective Studies | Sepsis - congenital | Alkaline Phosphatase - blood | Infant, Newborn | Penicillanic Acid - analogs & derivatives | Piperacillin - therapeutic use | Sepsis | Dosage and administration | Drug therapy, Combination | Drug therapy | Patient outcomes | Index Medicus
gentamicin | necrotizing enterocolitis | ampicillin | piperacillintazobactam | diaper rash | IN-VITRO | EARLY-ONSET SEPSIS | ANTIBIOTIC EXPOSURE | RISK | PEDIATRICS | piperacillin-tazobactam | OBSTETRICS & GYNECOLOGY | Infant, Very Low Birth Weight | Humans | Male | Treatment Outcome | Ampicillin - administration & dosage | Gentamicins - administration & dosage | Infant, Premature, Diseases - drug therapy | Sepsis - drug therapy | Diaper Rash - prevention & control | Apgar Score | Infant, Premature | Penicillanic Acid - therapeutic use | Female | Retrospective Studies | Sepsis - congenital | Alkaline Phosphatase - blood | Infant, Newborn | Penicillanic Acid - analogs & derivatives | Piperacillin - therapeutic use | Sepsis | Dosage and administration | Drug therapy, Combination | Drug therapy | Patient outcomes | Index Medicus
Journal Article
International Journal of Infectious Diseases, ISSN 1201-9712, 2006, Volume 10, Issue 2, pp. S9 - S16
Effective empirical antimicrobial therapy has led to a better outcome for febrile neutropenic patients. Guidelines are based mainly on expert opinion, current...
Febrile | Review | Piperacillintazobactam | Neutropenia | Guidelines | CEFTAZIDIME PLUS AMIKACIN | FEBRILE NEUTROPENIC PATIENTS | INFECTIOUS DISEASES | MONOTHERAPY | METAANALYSIS | PIPERACILLIN-TAZOBACTAM | CANCER-CHEMOTHERAPY | tazobactam | neutropenia | PERSISTENT FEVER | review | DOUBLE-BLIND | guidelines | piperacillin | PLACEBO-CONTROLLED TRIAL | EMPIRIC THERAPY | febrile | Antibiotics | Practice guidelines (Medicine) | Evidence-based medicine
Febrile | Review | Piperacillintazobactam | Neutropenia | Guidelines | CEFTAZIDIME PLUS AMIKACIN | FEBRILE NEUTROPENIC PATIENTS | INFECTIOUS DISEASES | MONOTHERAPY | METAANALYSIS | PIPERACILLIN-TAZOBACTAM | CANCER-CHEMOTHERAPY | tazobactam | neutropenia | PERSISTENT FEVER | review | DOUBLE-BLIND | guidelines | piperacillin | PLACEBO-CONTROLLED TRIAL | EMPIRIC THERAPY | febrile | Antibiotics | Practice guidelines (Medicine) | Evidence-based medicine
Journal Article
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