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chemistry, organic (42) 42
piperidinone (30) 30
piperidinones (22) 22
chemistry (13) 13
alkaloids (12) 12
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hydrogen bonding (9) 9
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pyridine (7) 7
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substituted piperidinones (6) 6
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ACS Catalysis, ISSN 2155-5435, 06/2015, Volume 5, Issue 6, pp. 3700 - 3703
Journal Article
SYNLETT, ISSN 0936-5214, 04/2019, Volume 30, Issue 7, pp. 821 - 826
Herein is reported the synthesis of polyfunctionalised piperidines and 2-piperidinones, through hydrogen atom transfer (HAT) chemistry catalysed by Fe(acac)... 
Michael addition | FUNCTIONALIZATION | radicals | ALPHA-ARYLATION | piperidines | CHEMISTRY, ORGANIC | piperidinone | iron | HAT | ASYMMETRIC HYDROGENATION | DERIVATIVES
Journal Article
ACS Catalysis, ISSN 2155-5435, 09/2016, Volume 6, Issue 9, pp. 5904 - 5907
A catalytic, enzyme-initiated (aza-) Achmatowicz reaction is presented. The involvement of a robust vanadium-dependent peroxidase from Curvularia inaequalis... 
oxidation | hypohalogenites | peroxidase | biocatalysis | Achmatowicz reaction | ENTRY | VANADIUM CHLOROPEROXIDASE | CHEMISTRY, PHYSICAL | PIPERIDINONES | CURVULARIA-INAEQUALIS | OXYFUNCTIONALIZATION REACTIONS
Journal Article
ACS Catalysis, ISSN 2155-5435, 06/2015, Volume 5, Issue 6, pp. 3700 - 3703
Asymmetric formal aza-Diels–Alder reactions with α,β-unsaturated ketones and 3H-indoles with disubstituted groups on the C3 position catalyzed by primary... 
bifunctional catalyst | IMINES | CHEMISTRY, PHYSICAL | asymmetric catalysis | DIENOPHILES | MICHAEL ADDITION | DESYMMETRIZATION | cycloaddition | aza-Diels-Alder | BRONSTED ACIDS | CONSTRUCTION | ENONES | piperidinone | amine | ACCESS | NITROALKENES | CONJUGATE ADDITION
Journal Article
Acta crystallographica. Section E, Structure reports online, ISSN 1600-5368, 08/2014, Volume 70, Issue Pt 8, p. o883
In the title compound, C26H26N2O2, the piperidine ring exhibits a chair conformation. The phenyl rings are attached to the central heterocycle in an equatorial... 
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 08/2014, Volume 5, Issue 8, pp. 894 - 899
Continued optimization of the N-substituent in the piperidinone series provided potent piperidinone–pyridine inhibitors 6, 7, 14, and 15 with improved... 
MDM2 | pyridine | piperidinone | protein-protein interaction | p53 | APOPTOSIS | CHEMISTRY, MEDICINAL | PROTEIN | CLINICAL DEVELOPMENT | CANCER-THERAPY
Journal Article
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, ISSN 0108-2701, 08/2014, Volume 70, pp. 817 - U280
Molecules of (S)-6-oxo-1-(thiophen-2-ylmethyl)piperidine-2-carboxylic acid, C11H13NO3S, crystallize as single enantiomers in the space group P2(1) and the... 
hydrogen bonding | disorder | pharmaceutical compounds | piperidinecarboxylic acids | 4-PIPERIDONE DERIVATIVES | crystal structure | CRYSTALS | piperidinone | electronic structures | CRYSTALLOGRAPHY
Journal Article
Tetrahedron, ISSN 0040-4020, 09/2003, Volume 59, Issue 38, pp. 7491 - 7496
To develop a method of synthesis of the potentially physiologically active compounds, 1′-substituted 6-amino-spiro-4-(piperidine-4′... 
pyrazole | Michael adduct | piperidinone | pyran | pyranopyrazole | spiro compounds | Piperidinone | Pyran | Pyranopyrazole | Pyrazole | Spiro compounds | NITRILES | CHEMISTRY, ORGANIC | Nitriles
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 04/2011, Volume 52, Issue 14, pp. 1549 - 1552
A three-component diastereoselective vinylogous Mannich-type reaction (VMR) with the silyl ketene acetal ( ) was developed. Adducts from the reactions provided... 
Piperidinone | Asymmetric synthesis | Piperidine | Anabasine | Vinylogous Mannich reaction | PYRROLIDINE | ACID | DIELS-ALDER REACTIONS | IMINES | CHEMISTRY, ORGANIC | ALKALOIDS | Tetrahedrons | Strategy | Synthesis (chemistry) | Construction | Ketenes | Adducts
Journal Article
Russian Journal of General Chemistry, ISSN 1070-3632, 8/2019, Volume 89, Issue 8, pp. 1673 - 1682
New piperidinone incorporating pyrimidine, triazine, diazipine, oxatriazine, and thiazole derivatives have been synthesized starting with... 
Chemistry | oxatriazine | Chemistry/Food Science, general | diazipine | MCF-7 | thiazole | HCT-116 | piperidinone | thiazolopyrimidine | pyrimidine | anticancer | THIOGLYCOSIDES | PYRIDINE | ALPHA | CHEMISTRY, MULTIDISCIPLINARY | AMINES | Care and treatment | Pyrimidines | Triazoles | Tanning | Cancer
Journal Article
Acta Crystallographica Section E: Structure Reports Online, ISSN 2056-9890, 2014, Volume 70, Issue 8, pp. o883 - O883
In the title compound, C26H26N2O2, the piperidine ring exhibits a chair conformation. The phenyl rings are attached to the central heterocycle in an equatorial... 
oxime | hydrogen bonding | piperidinone | CRYSTALLOGRAPHY | crystal structure
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2018, Volume 159, pp. 1 - 9
Journal Article
Journal Article
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, ISSN 1068-1620, 03/2017, Volume 43, Issue 2, pp. 186 - 196
The synthesis of novel thiazole-based piperidinone oximes and screening of their antioxidant and antimicrobial activity are described. The obtained results... 
antibacterial activity | MODEL SYSTEMS | hydrazinyl thiazoles | piperidinone oximes | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | antioxidant activity | antifungal activity | DERIVATIVES | Antioxidants | Sulfur compounds | Explosives | Antibacterial agents
Journal Article
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