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1. Full Text Cell-Based Measures of Viral Persistence Are Associated With Immune Activation and Programmed Cell Death Protein 1 (PD-1)—Expressing CD4+T cells
by Hiroyu Hatano and Vivek Jain and Peter W. Hunt and Tzong-Hae Lee and Elizabeth Sinclair and Tri D. Do and Rebecca Hoh and Jeffrey N. Martin and Joseph M. McCune and Frederick Hecht and Michael P. Busch and Steven G. Deeks
The Journal of Infectious Diseases, ISSN 0022-1899, 7/2013, Volume 208, Issue 1, pp. 50 - 56
Background. Studies aimed at defining the association between host immune responses and human immunodeficiency virus (HIV) persistence during therapy are... 
T lymphocytes | HIV/AIDS | Antiretrovirals | Highly active antiretroviral therapy | HIV | RNA | DNA | AIDS | Blood plasma | HIV 1 | Virology | D-dimer | 2-LTR circles | ongoing viral replication | raltegravir intensification | SUPPRESSIVE ANTIRETROVIRAL THERAPY | LOW-LEVEL VIREMIA | LYMPHATIC TISSUE FIBROSIS | PLASMA VIREMIA | INFECTIOUS DISEASES | HIV-INFECTED INDIVIDUALS | MICROBIOLOGY | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | POLYMERASE-CHAIN-REACTION | DISEASE PROGRESSION | HAART | DNA, Viral - drug effects | HIV Infections - virology | Humans | Middle Aged | Male | RNA, Viral - blood | CD4 Lymphocyte Count | Programmed Cell Death 1 Receptor - blood | HIV - drug effects | Antiretroviral Therapy, Highly Active | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | Proviruses - drug effects | Lymphocyte Activation - immunology | Immunity, Cellular - drug effects | Lymphocyte Activation - drug effects | Adult | Female | HIV Infections - drug therapy | Immune response | CD4 lymphocytes | Development and progression | Genetic aspects | Research | HIV infection | Apoptosis | Index Medicus | Abridged Index Medicus | Major and Brief Reports
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2. Full Text BAFF and CD4(+) T cells are major survival factors for long-lived splenic plasma cells in a B-cell-depletion context
by Thai, LH and Le Gallou, S and Robbins, A and Crickx, E and Fadeev, T and Zhou, ZC and Cagnard, N and Megret, J and Bole, C and Weill, JC and Reynaud, CA and Mahevas, M
BLOOD, ISSN 0006-4971, 04/2018, Volume 131, Issue 14, pp. 1545 - 1555
Previous data have suggested that B-cell-depletion therapy may induce the settlement of autoreactive long-lived plasma cells (LLPCs) in the spleen of patients... 
RHEUMATOID-ARTHRITIS | MAINTENANCE | LUPUS | DENDRITIC CELLS | MEMORY | AFFINITY MATURATION | IMMUNOTHERAPY | AUTOIMMUNITY | RITUXIMAB | HUMORAL IMMUNITY | HEMATOLOGY | Spleen - immunology | Cell Survival | Lymphocyte Depletion | CD4-Positive T-Lymphocytes - pathology | Plasma Cells - pathology | CD4-Positive T-Lymphocytes - immunology | Animals | Lupus Erythematosus, Systemic - immunology | B-Cell Activating Factor - immunology | Mice | Spleen - pathology | Lupus Erythematosus, Systemic - pathology | Disease Models, Animal | Plasma Cells - immunology | Index Medicus | Abridged Index Medicus
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3. Full Text Preferential Generation of Follicular B Helper T Cells from Foxp3⁺ T Cells in Gut Peyer's Patches
by Masayuki Tsuji and Noriko Komatsu and Shimpei Kawamoto and Keiichiro Suzuki and Osami Kanagawa and Tasuku Honjo and Shohei Hori and Sidonia Fagarasan
Science, ISSN 0036-8075, 3/2009, Volume 323, Issue 5920, pp. 1488 - 1492
Most of the immunoglobulin A (IgA) in the gut is generated by B cells in the germinal centers of Peyer's patches through a process that requires the presence... 
T lymphocytes | Spleen | Molecules | Peyers patches | Cytokines | B lymphocytes | Plasma cells | AIDS | Reports | Mice | Small intestine | GERMINAL CENTER FORMATION | CXC CHEMOKINE RECEPTOR-5 | POPULATION | ACTIVATION | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | RETINOIC-ACID | DIFFERENTIATION | INTERLEUKIN-21 | LAMINA PROPRIA | EXPRESSION | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | Spleen - immunology | T-Lymphocyte Subsets - cytology | Dendritic Cells - immunology | Germinal Center - immunology | Gene Expression Profiling | Adoptive Transfer | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | CD40 Antigens - metabolism | Forkhead Transcription Factors - metabolism | T-Lymphocytes, Helper-Inducer - immunology | T-Lymphocytes, Helper-Inducer - cytology | T-Lymphocytes, Regulatory - cytology | Cell Differentiation | Intestine, Small - immunology | T-Lymphocytes, Helper-Inducer - metabolism | Lymphocyte Activation | CD4-Positive T-Lymphocytes - cytology | Down-Regulation | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | Spleen - cytology | Lymph Nodes - immunology | Forkhead Transcription Factors - genetics | Lymph Nodes - cytology | Peyer's Patches - cytology | Animals | B-Lymphocytes - immunology | Intestine, Small - cytology | T-Lymphocyte Subsets - metabolism | Dendritic Cells - cytology | Immunoglobulin A, Secretory - biosynthesis | Peyer's Patches - immunology | Lymphatic system | Immunology | Cellular biology | Gene expression | Rodents | Index Medicus
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4. Full Text Natural killer (NK)-dendritic cell interactions generate MHC class II-dressed NK cells that regulate CD4⁺ T cells
by Masafumi Nakayama and Kazuyoshi Takeda and Mitsuko Kawano and Toshiyuki Takai and Naoto Ishii and Kouetsu Ogasawara
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2011, Volume 108, Issue 45, pp. 18360 - 18365
Natural killer (NK) cells contribute to not only innate but also to adaptive immunity by interacting with dendritic cells (DCs) and T cells. All activated... 
T lymphocytes | Molecules | Dendritic cells | Natural killer T cells | Cell lines | Antigen presenting cells | Cultured cells | Cellular immunity | Natural killer cells | Physiological regulation | ADAPTIVE IMMUNITY | ACTIVATION | NKG2D | DENDRITIC CELLS | INTERCELLULAR TRANSFER | MULTIDISCIPLINARY SCIENCES | INNATE | ANTIGENS | PROTEINS | SUBSET | MOLECULES | CD4-Positive T-Lymphocytes - immunology | Microscopy, Confocal | Animals | Histocompatibility Antigens Class II - immunology | Dendritic Cells - immunology | Humans | Mice, Inbred C57BL | Killer Cells, Natural - immunology | Mice | Reverse Transcriptase Polymerase Chain Reaction | Hypersensitivity, Delayed - immunology | Proteins | Gene expression | Rodents | Cells | Binding sites | Index Medicus | Cell proliferation | Spleen | Antigen presentation | Animal models | CD86 antigen | Hypersensitivity (delayed) | Immune response (cell-mediated) | CD80 antigen | Lymphocytes T | DAP10 protein | Cell interactions | Adoptive transfer | CD4 antigen | Costimulator | Major histocompatibility complex | Plasma membranes | Histocompatibility antigen HLA | Biological Sciences
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5. Full Text A proliferation-inducing ligand sustains the proliferation of human naïve (CD27−) B cells and mediates their differentiation into long-lived plasma cells in vitro via transmembrane activator and calcium modulator and cyclophilin ligand interactor and B-cell mature antigen
by Matsuda, Yoshiko and Haneda, Masataka and Kadomatsu, Kenji and Kobayashi, Takaaki
Cellular Immunology, ISSN 0008-8749, 06/2015, Volume 295, Issue 2, pp. 127 - 136
Long-lived plasma cells (PCs) contribute to humoral immunity through an undefined mechanism. Memory B cells, but not human naïve B cells, can be induced to... 
A proliferation-inducing ligand | Transmembrane activator and calcium modulator and cyclophilin ligand interactor | Long-lived plasma cell | B-cell mature antigen | Naïve B cell | SURVIVAL | BAFF | GERMINAL CENTER B | BONE-MARROW | T-FOLLICULAR-HELPER | IMMUNOLOGY | MEMORY B | CELL BIOLOGY | HUMORAL IMMUNITY | GENE-EXPRESSION | Naive B cell | SECRETING CELLS | NF-KAPPA-B | B-Cell Maturation Antigen - immunology | Antibodies, Monoclonal - pharmacology | Humans | Middle Aged | Male | Tumor Necrosis Factor Ligand Superfamily Member 13 - pharmacology | Young Adult | Cell Differentiation - immunology | B-Lymphocytes - immunology | Flow Cytometry | Cell Differentiation - drug effects | Adult | Female | Cell Culture Techniques | Transmembrane Activator and CAML Interactor Protein - antagonists & inhibitors | Transmembrane Activator and CAML Interactor Protein - immunology | B-Cell Maturation Antigen - antagonists & inhibitors | Antigens | B cells | Index Medicus
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6. Phospholipid metabolism in cellular signaling
by Mato, José M
1990, ISBN 9780849359781, 145 p. :$bill. ;$c27 cm.
Membrane lipids | Cell interaction | Cellular signal transduction | Metabolism
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7. Full Text Human IgE+ B cells are derived from T cell–dependent and T cell–independent pathways
by Berkowska, Magdalena A., PhD and Heeringa, Jorn J., MD and Hajdarbegovic, Enes, MD and van der Burg, Mirjam, PhD and Thio, H. Bing, MD, PhD and van Hagen, P. Martin, MD, PhD and Boon, Louis, PhD and Orfao, Alberto, MD, PhD and van Dongen, Jacques J.M., MD, PhD and van Zelm, Menno C., PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 3, pp. 688 - 697.e6
Background The prevalence of IgE-mediated diseases has been increasing worldwide, yet IgE-expressing B cells are poorly characterized, mainly because of their... 
Allergy and Immunology | B cell | atopic dermatitis | plasma cell | IgE | CD40 ligand | NASAL-MUCOSA | IMMUNOGLOBULIN-E SYNTHESIS | BRONCHIAL MUCOSE | HUMAN NAIVE | MEMORY | ALLERGY | IN-VIVO | CLASS-SWITCH RECOMBINATION | PERIPHERAL-BLOOD | IMMUNOLOGY | EXPRESSION | PLASMA-CELLS | Somatic Hypermutation, Immunoglobulin | Cell Separation | Germinal Center - immunology | Humans | Immunoglobulin E - metabolism | Cells, Cultured | Cell Communication | Hypersensitivity - immunology | B-Lymphocytes - immunology | CD40 Ligand - metabolism | Flow Cytometry | CD40 Ligand - genetics | T-Lymphocytes, Helper-Inducer - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 7 - metabolism | Immunologic Memory | Immunoglobulin Class Switching | Immunoglobulins | Mutation | Allergies | Immune system | Index Medicus | Abridged Index Medicus
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8. Full Text Essential Role of IL-21 in B Cell Activation, Expansion, and Plasma Cell Generation during CD4+ T Cell-B Cell Collaboration
by Kuchen, Stefan and Robbins, Rachel and Sims, Gary P and Sheng, Chen and Phillips, Terence M and Lipsky, Peter E and Ettinger, Rachel
The Journal of Immunology, ISSN 0022-1767, 11/2007, Volume 179, Issue 9, pp. 5886 - 5896
During T cell-B cell collaboration, plasma cell (PC) differentiation and Ig production are known to require T cell-derived soluble factors. However, the exact... 
RESPONSES | IMMUNOAFFINITY CAPILLARY-ELECTROPHORESIS | MEMORY | IMMUNOGLOBULIN | CD40 LIGAND | RECEPTOR | ANTIBODY | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | LYMPHOCYTES-T | B-Lymphocytes - cytology | Humans | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Interleukins - metabolism | CD4-Positive T-Lymphocytes - immunology | Plasma Cells - drug effects | B-Lymphocytes - drug effects | Immunity, Innate - immunology | Lymphocyte Activation - immunology | B-Lymphocytes - immunology | Lymphocyte Activation - drug effects | Interleukins - immunology | CD3 Complex - immunology | Antibodies - immunology | Cell Differentiation | Cell Proliferation - drug effects | Interleukins - pharmacology | CD4-Positive T-Lymphocytes - drug effects | Immunologic Memory - immunology | Plasma Cells - cytology | Plasma Cells - immunology | Index Medicus | Abridged Index Medicus
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9. Full Text Memory CD8+ T cells colocalize with IL‐7+ stromal cells in bone marrow and rest in terms of proliferation and transcription
by Sercan Alp, Özen and Durlanik, Sibel and Schulz, Daniel and McGrath, Mairi and Grün, Joachim R and Bardua, Marcus and Ikuta, Koichi and Sgouroudis, Evridiki and Riedel, René and Zehentmeier, Sandra and Hauser, Anja E and Tsuneto, Motokazu and Melchers, Fritz and Tokoyoda, Koji and Chang, Hyun‐Dong and Thiel, Andreas and Radbruch, Andreas
European Journal of Immunology, ISSN 0014-2980, 04/2015, Volume 45, Issue 4, pp. 975 - 987
It is believed that memory CD8 + T cells are maintained in secondary lymphoid tissues, peripheral tissues, and BM by homeostatic proliferation. Their survival... 
CD8 T cell | Bone marrow | Memory cells | Gene expression | Interleukin‐7 | Interleukin-7 | SURVIVAL | IMMUNE-RESPONSE | SITE | IMMUNOLOGICAL MEMORY | RM CELLS | IMMUNOLOGY | SECONDARY LYMPHOID ORGANS | HOMEOSTATIC PROLIFERATION | IN-VIVO | LIVED PLASMA-CELLS | ANTIGEN | Cell Proliferation | Antigens, CD - biosynthesis | Bone Marrow Cells - cytology | Mice, Inbred C57BL | Stromal Cells - immunology | Lectins, C-Type - biosynthesis | Animals | Interleukin-7 - immunology | Bone Marrow Cells - immunology | Resting Phase, Cell Cycle - immunology | Ki-67 Antigen - biosynthesis | Transcription, Genetic | Mice | Antigens, Differentiation, T-Lymphocyte - biosynthesis | CD8-Positive T-Lymphocytes - immunology | Interleukin-2 - biosynthesis | Immunologic Memory - immunology | Interferon-gamma - biosynthesis | Tumor Necrosis Factor Receptor Superfamily, Member 9 - biosynthesis | Genetic transcription | Interleukins | T cells | Analysis | Index Medicus | Highlights
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10. Full Text IL-6 Triggers IL-21 production by human CD4(+) T cells to drive STAT3-dependent plasma cell differentiation in B cells
by Diehl, Sean A and Schmidlin, Heike and Nagasawa, Maho and Blom, Bianca and Spits, Hergen
Immunology and cell biology, ISSN 0818-9641, 2012, Volume 90, Issue 8, pp. 802 - 811
Interleukin (IL)-21-producing CD4(+) T cells are central to humoral immunity. Deciphering the signals that induce IL-21 production in CD4(+) T cells and those... 
FH | IL‐21 | cells | T | BCL6 | STAT3 | human | IL‐6 | TFH cells | IL-21 | IL-6 | IMMUNOLOGY | CELL BIOLOGY | CXC CHEMOKINE RECEPTOR-5 | BLIMP-1 | FOLLICULAR-HELPER-CELLS | IMMUNE-RESPONSES | IN-VIVO | BCL-6 EXPRESSION | GENERATION | ANTIBODY-RESPONSES | T-FH cells | TRANSCRIPTION FACTOR | LYMPHOCYTES | Biomarkers - metabolism | Humans | CD4-Positive T-Lymphocytes - immunology | DNA-Binding Proteins - metabolism | Plasma Cells - drug effects | Cell Differentiation - immunology | Animals | Interleukin-6 - pharmacology | Cell Differentiation - drug effects | Mice | Interleukins - biosynthesis | Immunoglobulins - biosynthesis | CD4-Positive T-Lymphocytes - drug effects | Plasma Cells - cytology | STAT3 Transcription Factor - metabolism | Plasma Cells - immunology | Proto-Oncogene Proteins c-bcl-6 | Index Medicus | plasma cell differentiation
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11. Full Text Metabolic reprogramming commits differentiation of human CD27 + IgD + B cells to plasmablasts or CD27 - IgD - cells
by Torigoe, Masataka and Iwata, Shigeru and Nakayamada, Shingo and Sakata, Kei and Zhang, Mingzeng and Hajime, Maiko and Miyazaki, Yusuke and Narisawa, Manabu and Ishii, Koji and Shibata, Hirotaka and Tanaka, Yoshiya
Journal of Immunology, ISSN 0022-1767, 07/2017, Volume 199, Issue 2, pp. 425 - 434
B cells play a crucial role in the pathogenesis of autoimmune diseases, such as systemic lupus erythematosus (SLE). However, the relevance of the metabolic... 
PLASMACYTOID DENDRITIC CELLS | MAMMALIAN TARGET | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | MEMORY | IMMUNOGLOBULIN-M | TOLL-LIKE RECEPTORS | CPG-OLIGODEOXYNUCLEOTIDES | IMMUNOLOGY | T-CELLS | MTOR | Protein Kinases - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Immunoglobulin D - genetics | Male | Multiprotein Complexes - genetics | Immunoglobulin D - immunology | Mechanistic Target of Rapamycin Complex 1 | Plasma Cells - physiology | Toll-Like Receptor 9 - immunology | Young Adult | Multiprotein Complexes - metabolism | Flow Cytometry | TOR Serine-Threonine Kinases - genetics | Lupus Erythematosus, Systemic - immunology | Lactic Acid - biosynthesis | Adult | B-Lymphocyte Subsets - immunology | Female | Plasma Cells - metabolism | Tumor Necrosis Factor Receptor Superfamily, Member 7 - immunology | Oligodeoxyribonucleotides - immunology | Immunophenotyping | Immunoglobulin D - deficiency | Tumor Necrosis Factor Receptor Superfamily, Member 7 - genetics | Interferon-alpha - immunology | B-Lymphocytes - drug effects | Metabolic Networks and Pathways - genetics | B-Lymphocytes - immunology | B-Lymphocyte Subsets - metabolism | Cell Differentiation - drug effects | Adolescent | Immunologic Memory | Aged | Plasma Cells - immunology | TOR protein | CD27 antigen | Lymphocyte receptors | Pathogenesis | Activation | Immunoglobulin D | Kinases | AMP-activated protein kinase | Cell activation | Systemic lupus erythematosus | Toll-like receptors | CpG islands | Immunological memory | Memory cells | CD19 antigen | AMP | Rapamycin | Metabolism | TLR9 protein | Chronic conditions | Lymphocytes B | Glycolysis | Interferon | Lactic acid | Autoimmune diseases | Differentiation | Index Medicus | Abridged Index Medicus
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