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Antimicrobial activity in vitro of plumbagin isolated from plumbago species, 12/2003
Plumbagin is a naturally occurring naphthoquinone isolated from roots of Plumbago scandens   . The plant was collected at the Campus of Fundação Oswaldo Cruz,... 
Plumbago scandens   - plumbagin - antimicrobial activity
Journal
Antimicrobial Activity and Chemical Investigation of Brazilian Drosera, 11/2004
The antimicrobial activity of three different extracts (hexanic, ethyl acetate, methanol) obtained from Brazilian Drosera species (D. communis, D. montana var.... 
Microbiology | Tropical Diseases | Drosera species - Droseraceae - antimicrobial activity - plumbagin - aliphatic compounds oc04152
Journal
Life Sciences, ISSN 0024-3205, 08/2019, Volume 231, pp. 116422 - 116422
This study was performed to evaluate the antidiabetic and wound healing activity of plumbagin in diabetic rats by macroscopical, biochemical, histological,... 
Wound healing | Plumbagin | Nrf2 | Anti-inflammatory | Antidiabetic | Index Medicus
Journal Article
10/2013
Purpose: To investigate the protective effects of plumbagin against liver fibrosis and explore the influence of plumbagin on the proliferation of hepatic... 
Plumbagin | Leptin | Proliferation | Hepatic stellate cell | Anti-inflammatory | Signal transduction pathway
Web Resource
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 08/2019, Volume 116, pp. 108923 - 108923
The mechanism of Plumbagin ameliorates liver fibrosis via a ROS-mediated NF-кB signaling pathway. The oxidative stress and the NF-κB signaling pathway are... 
Liver fibrosis | NF-кB signaling pathway | Plumbagin | ROS
Journal Article
Journal Article
by Zhou, Rui and Wu, Ka and Su, Min and Li, Rong
Environmental Toxicology and Pharmacology, ISSN 1382-6689, 08/2019, Volume 70, pp. 103200 - 103200
Plumbagin exerts effective anti-hepatocellular carcinoma (HCC) benefits, however, the detailed mechanisms behind these effects are not yet completely... 
Hepatocellular carcinoma | Network pharmacology | Targets | Plumbagin | Molecular mechanisms | Index Medicus
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 05/2018, Volume 101, pp. 379 - 390
Although plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) protects against cerebral ischemia and spinal cord injury-induced oxidative stress and inflammation... 
β-secretase | Trigonelline | Plumbagin | Alzheimer’s disease | Astrocytes | GFAP
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2004, Volume 45, Issue 38, pp. 7115 - 7119
Ellis accumulates a large amount of plumbagin ( ), which operates as an antifeedant against predators. Content of reached 0.5% weight of the fresh trap lobes.... 
Plumbagin | Antifeedant | antifeedant | CHEMISTRY, ORGANIC | plumbagin
Journal Article
Research Journal of Pharmacy and Technology, ISSN 0974-3618, 08/2016, Volume 9, Issue 8, pp. 1019 - 1022
Journal Article
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 07/2019, Volume 10
Resistance acquired toward anti-cancer agents is a significant drawback in breast cancer therapy. A key factor contributing to drug resistance is apoptosis... 
MAPK pathway | SURVIVAL | ACTIVATION | TRANSCRIPTION | BCL-2 FAMILY PROTEINS | apoptosis | breast cancer | PLUMBAGIN | BH3 MIMETIC ABT-737 | Mcl-1 | SIGNALING PATHWAY | RESISTANCE | PHARMACOLOGY & PHARMACY | plumbagin derivatives | NF-KAPPA-B | Proteins | Care and treatment | Cancer cells | Breast cancer | Biochemistry | Drug resistance | Cancer | Apoptosis
Journal Article
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, ISSN 1600-5368, 11/2009, Volume 65, pp. O2737 - U632
In the title compound, C15H14O5, an intramolecular O-H center dot center dot center dot O hydrogen bond occurs. In the crystal, the molecules form inversion... 
PLUMBAGIN | CRYSTALLOGRAPHY
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 01/2019, Volume 219, Issue 3, pp. 459 - 469
Abstract Background The stress response adaptability of Mycobacterium tuberculosis (Mtb) is still unresolved. In this study, we ascribe an important function... 
CELLS | INFECTIOUS DISEASES | plumbagin | MACROPHAGES | triclosan | MICROBIOLOGY | MmpL6 | IMMUNOLOGY | OXYGEN | INHIBITION | Mycobacterium tuberculosis | GENE-EXPRESSION | RESISTANCE | INHA | oxidative stress
Journal Article
Acta pharmacologica Sinica, ISSN 1671-4083, 05/2019, Volume 40, Issue 8, pp. 1127 - 1128
The authors regretted to find the mis-representative images in Fig. 3a, c and Fig. 4a, c when re-read our previously published article Synergistic suppression... 
Acids | Plumbagin | Negligence | Zoledronic acid | Breast cancer | Pharmacology | Synergistic effect | Apoptosis | Index Medicus
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 01/2019, Volume 123, pp. 492 - 500
Plumbagin (5-hydroxy-2-methyl-1,4-naphthaquinone) has displayed antitumor activity and in animal models; however, the underlying molecular mechanisms have not... 
Nepenthes alata | Reactive oxygen species | Plumbagin | Anticancer | Apoptosis | p53 | ARREST | FOOD SCIENCE & TECHNOLOGY | DOXORUBICIN | GROWTH | TOXICOLOGY | INHIBITOR | Index Medicus
Journal Article
Cell death & disease, ISSN 2041-4889, 05/2019, Volume 10, Issue 5, pp. 371 - 1
This article has been retracted at the request of the authors. After publication, the authors found that in Figure 2B-a the first two images in the third row... 
Osteoclastogenesis | Zoledronic acid | Extracellular signal-regulated kinase | Adenosine | Breast cancer | Plumbagin
Journal Article
Journal of Pharmacological Sciences, ISSN 1347-8613, 2014, Volume 124, Issue 4, pp. 486 - 493
Abstract. Plumbagin, a naphthoquinone derived from the medicinal plant Plumbago zeylanica, has been shown to exert anti-cancer and anti-proliferative... 
Journal Article
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