X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (1168) 1168
hiv-1 - genetics (807) 807
virology (783) 783
index medicus (614) 614
molecular sequence data (525) 525
hiv infections - virology (495) 495
infectious diseases (458) 458
female (452) 452
male (450) 450
hiv (433) 433
pol gene products, human immunodeficiency virus - genetics (425) 425
immunology (376) 376
adult (369) 369
animals (361) 361
phylogeny (338) 338
viruses (313) 313
mutation (300) 300
hiv-1 - classification (276) 276
base sequence (272) 272
hiv-1 - isolation & purification (258) 258
sequence analysis, dna (257) 257
genotype (255) 255
amino acid sequence (254) 254
hiv-1 - drug effects (243) 243
middle aged (239) 239
hiv infections - epidemiology (237) 237
infection (228) 228
gene products, pol - genetics (226) 226
hiv-1 (226) 226
immunodeficiency-virus type-1 (216) 216
cell line (211) 211
human-immunodeficiency-virus (206) 206
virus diseases (192) 192
research (186) 186
research article (185) 185
hiv infections - drug therapy (183) 183
human immunodeficiency virus--hiv (177) 177
drug resistance (170) 170
microbiology (167) 167
genes, pol (165) 165
hiv-1 - immunology (165) 165
gene products, gag - genetics (164) 164
prevalence (161) 161
aids (160) 160
hiv-1 - physiology (157) 157
molecular epidemiology (153) 153
viral load (151) 151
reverse-transcriptase (149) 149
genetic aspects (145) 145
young adult (145) 145
rna, viral - genetics (142) 142
gene products, gag - metabolism (138) 138
health aspects (138) 138
drug resistance, viral - genetics (137) 137
hiv infections - transmission (135) 135
hiv infection (133) 133
hiv infections - immunology (133) 133
adolescent (132) 132
replication (132) 132
drug resistance, viral (129) 129
human immunodeficiency virus (129) 129
genetic variation (126) 126
mutations (126) 126
polymerase chain reaction (126) 126
anti-hiv agents - pharmacology (123) 123
analysis (122) 122
antiretroviral therapy (122) 122
virus replication (119) 119
biochemistry & molecular biology (118) 118
cluster analysis (117) 117
aids/hiv (116) 116
dna (116) 116
epidemiology (116) 116
hiv-1 - enzymology (116) 116
gag gene products, human immunodeficiency virus - genetics (114) 114
proteins (114) 114
recombination, genetic (113) 113
type-1 (113) 113
multidisciplinary sciences (111) 111
pol gene (110) 110
gene products, gag - immunology (105) 105
gene products, pol - immunology (105) 105
drug-resistance (103) 103
identification (103) 103
acquired immune deficiency syndrome--aids (102) 102
article (98) 98
mice (97) 97
expression (96) 96
fusion proteins, gag-pol - genetics (95) 95
medicine (95) 95
anti-hiv agents - therapeutic use (93) 93
fusion proteins, gag-pol - metabolism (93) 93
antiviral agents (92) 92
genes, gag (91) 91
rna (90) 90
science (90) 90
hiv reverse transcriptase - genetics (89) 89
biotechnology & applied microbiology (87) 87
infections (87) 87
hiv protease - genetics (86) 86
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e21225
Background: The safety and immunogenicity of a vaccine regimen consisting of a 6-plasmid HIV-1 DNA prime (envA, envB, envC, gagB, polB, nefB) boosted by a... 
RESPONSES | IMMUNITY | ASSAY | SAFETY | MULTIDISCIPLINARY SCIENCES | ANTIBODY | IMMUNOGENICITY EVALUATION | CANDIDATE | INFECTION | STEP | MEMORY T-CELLS | env Gene Products, Human Immunodeficiency Virus - immunology | Immunization, Secondary - adverse effects | Immunoglobulin G - blood | Human Immunodeficiency Virus Proteins - immunology | Humans | Middle Aged | AIDS Vaccines - immunology | Vaccines, DNA - immunology | pol Gene Products, Human Immunodeficiency Virus - immunology | Male | Antibodies, Viral - blood | Vaccines, DNA - administration & dosage | Young Adult | env Gene Products, Human Immunodeficiency Virus - genetics | T-Lymphocytes - metabolism | Immunoglobulin G - immunology | Adenoviridae - genetics | Adult | Female | gag Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - genetics | Immunization - adverse effects | Enzyme-Linked Immunosorbent Assay | Immunization - methods | Anemia - chemically induced | Immunization, Secondary - methods | HIV-1 - genetics | HIV-1 - immunology | nef Gene Products, Human Immunodeficiency Virus - genetics | nef Gene Products, Human Immunodeficiency Virus - immunology | Interferon-gamma - immunology | Adolescent | Antibodies, Viral - immunology | Human Immunodeficiency Virus Proteins - genetics | T-Lymphocytes - immunology | AIDS Vaccines - administration & dosage | gag Gene Products, Human Immunodeficiency Virus - immunology | Interferon-gamma - blood | Cohort Studies | Oligomers | AIDS vaccines | Adenoviruses | Immunotherapy | DNA | Clinical trials | Product development | Interferon | Biological response modifiers | T cells | HIV (Viruses) | Antigenic determinants | Health care | CD8 antigen | Antibodies | Lymphocytes T | Infections | Vaccines | Epidemiology | Randomization | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Inserts | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Recombinant | Binding | Medical research | Immunoglobulins | Cytokines | Epitopes | Immune response (humoral) | CD4 antigen | Disease prevention | Hospitals | Infectious diseases | Immunogenicity | γ-Interferon | Adults | Cancer | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | Human immunodeficiency virus
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2017, Volume 25, Issue 5, pp. 1168 - 1186
CRISPR-associated protein 9 (Cas9)-mediated genome editing provides a promising cure for HIV-1/AIDS; however, gene delivery efficiency in vivo remains an... 
genome editing | humanized BLT mice | animal models | viral latency | HIV | AAV | Tg26 mice | gene therapy | Cas9 | gRNA | EFFICIENT DELIVERY | MEDICINE, RESEARCH & EXPERIMENTAL | GENE EDITING TECHNOLOGIES | PACKAGING CAPACITY | LENTIVIRAL VECTORS | ADENOASSOCIATED VIRAL VECTORS | STAPHYLOCOCCUS-AUREUS CAS9 | CRISPR-CAS9 NUCLEASES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CRISPR/CAS9 SYSTEM | GENETICS & HEREDITY | MODULATES PROLIFERATION | NEURAL PRECURSOR CELLS | Oligonucleotides - genetics | Dependovirus - genetics | Endonucleases - genetics | Staphylococcus aureus - enzymology | RNA, Guide - genetics | RNA, Guide - metabolism | Humans | HIV Long Terminal Repeat | pol Gene Products, Human Immunodeficiency Virus - metabolism | Endonucleases - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | HIV Infections - pathology | Proviruses - genetics | Base Sequence | Clustered Regularly Interspaced Short Palindromic Repeats | gag Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - genetics | Disease Models, Animal | Genome, Viral | HIV-1 - metabolism | Dependovirus - metabolism | Genetic Vectors - chemistry | HIV Infections - virology | Bacterial Proteins - genetics | Genetic Vectors - metabolism | Mice, Transgenic | HIV-1 - genetics | Proviruses - metabolism | Staphylococcus aureus - chemistry | Oligonucleotides - metabolism | Animals | CRISPR-Cas Systems | HIV Infections - therapy | Bacterial Proteins - metabolism | Gene Editing - methods | Mice | Genetic Therapy - methods | Neuroimaging | Animal models | Bioluminescence | Intravenous administration | Genes | Liver | Clinical trials | Chronic infection | Infections | Genomes | Thymus | Acquired immune deficiency syndrome--AIDS | Efficiency | Transgenic animals | Human immunodeficiency virus--HIV | Bone marrow | Colon | Deoxyribonucleic acid--DNA | Spleen | CRISPR | Gene transfer | Advisors | Transgenic mice | Ribonucleic acid--RNA | Progenitor cells | Polymerase chain reaction | Studies | Genotyping | Neural stem cells | Original
Journal Article
2011, 1. Aufl., Wiley series in drug discovery and development, ISBN 9781118015377, xiii, 506 p., [16] p. of plates
This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging... 
Antiviral agents | HIV Integrase | Enzymes | Inhibitors | Drug Design | pharmacology | HIV (Viruses) | HIV Integrase Inhibitors | Science | Chemistry | Industrial & Technical
Book
PLoS ONE, ISSN 1932-6203, 2012, Volume 7, Issue 4, p. e34723
HIV-1 candidate vaccines expressing an artificial polyprotein comprising Gag, Pol and Nef (GPN) and a secreted envelope protein (Env) were shown in recent... 
AIDS RESEARCH | IMMUNIZATION | T-CELL RESPONSES | VIRUS | PHASE-I TRIAL | IMMUNE-RESPONSES | BIOLOGY | ENVELOPE PROTEIN | INFECTION | NYVAC-C | EXPRESSION | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | Vaccines, DNA - immunology | pol Gene Products, Human Immunodeficiency Virus - immunology | Vaccines, Synthetic - immunology | Vaccines, DNA - administration & dosage | Clinical Trials, Phase III as Topic | env Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - biosynthesis | HEK293 Cells | Female | pol Gene Products, Human Immunodeficiency Virus - genetics | Gene Products, gag - immunology | Gene Products, gag - genetics | Vaccines, Synthetic - genetics | nef Gene Products, Human Immunodeficiency Virus - biosynthesis | HIV-1 - genetics | Gene Products, gag - biosynthesis | HIV-1 - immunology | Animals | env Gene Products, Human Immunodeficiency Virus - biosynthesis | nef Gene Products, Human Immunodeficiency Virus - genetics | nef Gene Products, Human Immunodeficiency Virus - immunology | Vaccines, Virus-Like Particle - immunology | Mice | Mice, Inbred BALB C | Vaccines, Synthetic - administration & dosage | AIDS vaccines | Viral proteins | Vaccination | DNA | Amino acids | T cells | HIV (Viruses) | Antigenic determinants | Competition | CD8 antigen | Clinical trials | Viruses | Lymphocytes T | DNA vaccines | Histocompatibility antigen H-2 | Vaccines | Virus-like particles | Proteins | Clonal deletion | Gag protein | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Combined vaccines | Deletion | Deoxyribonucleic acid--DNA | Medical research | Cytomegalovirus | Envelope protein | Gene expression | Nef protein | Immunogenicity | γ-Interferon | Budding | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | Human immunodeficiency virus
Journal Article
Journal Article
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 10, pp. 5330 - 5339
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 9, pp. 1 - 16
Background: We conducted a double-blind, randomized, placebo-controlled Phase I study of a recombinant replication-defective adenovirus type 5 (rAd5) vector... 
IMMUNITY | NEUTRALIZING ANTIBODIES | ASSAY | REPLICATION | MULTIDISCIPLINARY SCIENCES | CLINICAL-TRIALS | PHASE-1 SAFETY | CANDIDATE | INFECTION | GAG | T-CELLS | HIV Infections - prevention & control | Humans | Middle Aged | AIDS Vaccines - immunology | Vaccines, DNA - immunology | pol Gene Products, Human Immunodeficiency Virus - immunology | Genetic Vectors - adverse effects | Male | AIDS Vaccines - adverse effects | Young Adult | HIV Infections - immunology | Immunization, Secondary | Drug-Related Side Effects and Adverse Reactions | Adenoviridae - genetics | Adult | gag Gene Products, Human Immunodeficiency Virus - genetics | Adenoviridae - immunology | pol Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - adverse effects | Double-Blind Method | Genetic Vectors - immunology | HIV Infections - virology | HIV-1 - genetics | Genetic Vectors - genetics | HIV-1 - classification | HIV-1 - immunology | Vaccines, DNA - adverse effects | Adolescent | gag Gene Products, Human Immunodeficiency Virus - adverse effects | Antibodies, Viral - immunology | gag Gene Products, Human Immunodeficiency Virus - immunology | HIV antigens | Medical research | AIDS vaccines | Safety and security measures | Biological response modifiers | HIV (Viruses) | Adenoviruses | DNA | Medicine, Experimental | Genetic research | Interferon | Health aspects | HIV infection | Laboratories | Antibodies | Infections | DNA vaccines | Vaccines | Dosage | Immunity | Epidemiology | Proteins | Randomization | Immunology | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Safety | Public health | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Recombinant | Immune system | Antigens | Immunoglobulins | Immune response | Priming | Immune response (humoral) | Infectious diseases | Nef protein | Immunogenicity | γ-Interferon | Adults | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | Human immunodeficiency virus
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 11/2014, Volume 70, Issue 6, pp. 1833 - 1842
Objectives: The safety, immunogenicity, impact on the latent reservoir and rebound of viral load after therapeutic HIV-1 vaccination with recombinant modified... 
Disulfiram | Functional cure | Reservoir | Poxvirus | VIRAL LOAD | INFECTIOUS DISEASES | GAG VACCINE | FUNCTIONAL-AVIDITY | TREATMENT INTERRUPTION | ADULTS | poxvirus | MICROBIOLOGY | disulfiram | ANTIRETROVIRAL THERAPY | INDIVIDUALS | IMMUNIZATION | functional cure | T-CELL RESPONSES | PHARMACOLOGY & PHARMACY | INFECTION | reservoir | HIV Envelope Protein gp120 - genetics | Recombinant Fusion Proteins - immunology | Humans | Middle Aged | AIDS Vaccines - immunology | pol Gene Products, Human Immunodeficiency Virus - immunology | Male | Vaccines, Synthetic - immunology | Vaccinia virus - genetics | AIDS Vaccines - adverse effects | Viral Load | Drug Carriers | Anti-HIV Agents - administration & dosage | HIV Envelope Protein gp120 - immunology | Vaccination - methods | Vaccines, Synthetic - adverse effects | HIV-1 - isolation & purification | Adult | Female | gag Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - genetics | Placebos - administration & dosage | HIV-1 - genetics | Plasma - virology | HIV-1 - immunology | nef Gene Products, Human Immunodeficiency Virus - genetics | nef Gene Products, Human Immunodeficiency Virus - immunology | HIV Infections - therapy | Recombinant Fusion Proteins - genetics | Vaccines, Synthetic - administration & dosage | AIDS Vaccines - administration & dosage | gag Gene Products, Human Immunodeficiency Virus - immunology | Disulfiram - administration & dosage
Journal Article
Journal Article
Molecular Therapy, ISSN 1525-0016, 03/2015, Volume 23, Issue 3, pp. 591 - 601
This study evaluated the safety and immunogenicity of PENNVAX-B in 12 HIV infected individuals. PENNVAX-B is a combination of three optimized synthetic... 
MEDICINE, RESEARCH & EXPERIMENTAL | ELECTROPORATION | RESERVOIR | ELIMINATION | ANTIRETROVIRAL THERAPY | CD8(+) T-CELLS | REPLICATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | LYMPHOID-TISSUE | GENETICS & HEREDITY | FULL REPERTOIRE | EXPRESSION | LYMPHOCYTES | Consensus Sequence | Perforin - genetics | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | Middle Aged | Vaccination | AIDS Vaccines - immunology | pol Gene Products, Human Immunodeficiency Virus - immunology | Male | Granzymes - genetics | Leukocytes, Mononuclear - virology | HIV Infections - immunology | env Gene Products, Human Immunodeficiency Virus - genetics | HIV Infections - pathology | Leukocytes, Mononuclear - immunology | Adult | Female | Granzymes - biosynthesis | gag Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - genetics | env Gene Products, Human Immunodeficiency Virus - chemistry | HIV Infections - virology | Interferon-gamma - secretion | gag Gene Products, Human Immunodeficiency Virus - chemistry | pol Gene Products, Human Immunodeficiency Virus - chemistry | Enzyme-Linked Immunospot Assay | AIDS Vaccines - chemistry | Antiretroviral Therapy, Highly Active | Leukocytes, Mononuclear - pathology | HIV-1 - immunology | HIV Infections - therapy | Vaccines, Synthetic | AIDS Vaccines - genetics | AIDS Vaccines - administration & dosage | gag Gene Products, Human Immunodeficiency Virus - immunology | Immunity, Cellular | Interferon-gamma - biosynthesis | Perforin - biosynthesis | Original
Journal Article