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Yakugaku Zasshi, ISSN 0031-6903, 2013, Volume 133, Issue 5, pp. 519 - 526
Journal Article
YAKUGAKU ZASSHI, ISSN 0031-6903, 2013, Volume 133, Issue 5, pp. 519 - 526
Polyglutamine tract-binding protein 1 (PQBP1) is a nuclear protein that regulates transcription and pre-mRNA splicing. In addition, the mutations in the PQBP1... 
polyglutamine tract-binding protein 1 | NMR | intrinsically disordered protein (IDP) | pre-mRNA splicing
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 11/2005, Volume 95, Issue 3, pp. 858 - 870
Polyglutamine tract‐binding protein‐1 (PQBP‐1) is a nuclear protein that interacts and colocalizes with mutant polyglutamine proteins. We previously reported... 
neuron | transcription | polyglutamine | polyglutamine tract‐binding protein‐1 | transgenic mouse | degeneration | Transgenic mouse | Degeneration | Neuron | Polyglutamine | Transcription | Polyglutamine tract-binding protein-1 | APOPTOSIS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMYOTROPHIC-LATERAL-SCLEROSIS | NEUROSCIENCES | REPRESSES TRANSCRIPTION | LINKED MENTAL-RETARDATION | NITRIC-OXIDE | HYPERPOLARIZATION | polyglutamine tract-binding protein-1 | GROWTH-FACTOR | CYTOCHROME-C RELEASE | HUNTINGTONS-DISEASE | Mitochondria - enzymology | Oligonucleotide Array Sequence Analysis | Humans | Oxidative Stress - physiology | Nerve Degeneration - physiopathology | Mitochondria - ultrastructure | Motor Neurons - pathology | Motor Neurons - ultrastructure | Nerve Degeneration - metabolism | Electron Transport Complex IV - metabolism | Motor Neuron Disease - metabolism | Caspases - metabolism | Mitochondria - genetics | Up-Regulation - physiology | Anterior Horn Cells - ultrastructure | Motor Neuron Disease - physiopathology | Nuclear Proteins - genetics | Motor Neurons - physiology | Cytochromes c - metabolism | Anterior Horn Cells - pathology | Mice, Transgenic | Nuclear Proteins - metabolism | Membrane Potentials - physiology | Microscopy, Electron | Nerve Degeneration - pathology | Motor Neuron Disease - pathology | Anterior Horn Cells - physiology | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Cell Death - physiology | Mice | Proteins | Neurons | Transgenic animals | Genetic research | Amino acids | Cells | Neurological disorders | Index Medicus
Journal Article
FEBS Letters, ISSN 0014-5793, 12/2014, Volume 588, Issue 24, pp. 4583 - 4589
Polyglutamine tract-binding protein 1 (PQBP1) is an intrinsically disordered protein abundantly expressed in the brain. Mutations in the gene are causative for... 
Intra-molecular interaction | NMR | Intrinsically disordered protein | Segmental isotope-labeling | Expressed protein ligation | EPL | polar amino acid-rich domain | PRD | matrix-assisted laser desorption ionization time-of-flight mass analysis | WW domain | expressed protein ligation | C-segment | PQBP1 | IDP | PQBP1(1–219) with a C-terminal thioester group | C-terminal domain | high-performance liquid chromatography | sodium dodecyl sulfate–polyacrylamide gel electrophoresis | HPLC | residues 1–219 of PQBP1 | PQBP1(220–265) with a Gly220Cys mutation | intrinsically disordered protein | sodium 2-sulfanylethanesulfonate | N-fragment | WWD | N-segment | residues 220–265 of PQBP1 | polyglutamine tract-binding protein 1 | SDS–PAGE | nuclear magnetic resonance | MALDI-TOF MS | CTD | MESNA | C-fragment | POLYGLUTAMINE TRACT | TERMINAL DOMAIN | NMR-SPECTROSCOPY | BIOCHEMISTRY & MOLECULAR BIOLOGY | NATIVE CHEMICAL LIGATION | TRANSCRIPTION | N-15 | CELL BIOLOGY | BIOPHYSICS | ASSIGNMENT | U5-15KD | TRACT-BINDING PROTEIN-1 | RESIDUES | Isotope Labeling | Nuclear Proteins - metabolism | Magnetic Resonance Spectroscopy | Nuclear Proteins - chemistry | Intrinsically Disordered Proteins - chemistry | Intrinsically Disordered Proteins - metabolism | Proteins | Medical research | Surface active agents | Analysis | Medicine, Experimental | Nuclear magnetic resonance spectroscopy | Sulfates | Labeling | Mental illness | High performance liquid chromatography | Protein binding | Index Medicus
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 10/2006, Volume 99, Issue 1, pp. 70 - 83
Journal Article
Nature Communications, ISSN 2041-1723, 04/2014, Volume 5, Issue 1, p. 3822
A loss-of-function of polyglutamine tract-binding protein 1 (PQBP1) induced by frameshift mutations is believed to cause X-linked mental retardation. However,... 
WW DOMAIN | RENPENNING SYNDROME | POLYGLUTAMINE TRACT | LINKED MENTAL-RETARDATION | TERMINAL DOMAIN | MULTIDISCIPLINARY SCIENCES | DISEASE | MISSENSE MUTATION | MACHINE | TRACT-BINDING PROTEIN-1 | INSIGHTS
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2010, Volume 285, Issue 25, pp. 19391 - 19401
Journal Article
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 1999, Volume 8, Issue 6, pp. 977 - 987
Journal Article
by Zhang, Y and Zhao, HY and Xu, W and Jiang, DH and Huang, LX and Li, LS
JOURNAL OF CANCER, ISSN 1837-9664, 2019, Volume 10, Issue 9, pp. 2091 - 2101
Osteosarcoma (OS) is the most common primary bone malignancy, predominately affecting children and adolescents. Due to the introduction of chemotherapy, the... 
POLYGLUTAMINE TRACT | PROTEIN | PROGNOSTIC-FACTORS | TRANSCRIPTION | PQBP1 | recurrence | RENPENNING SYNDROME | WW DOMAIN | BIOINFORMATICS | ONCOLOGY | metastasis | HIGH-GRADE OSTEOSARCOMA | MUTATIONS | BINDING | osteosarcoma | PCK2
Journal Article
Nature Genetics, ISSN 1061-4036, 2003, Volume 35, Issue 4, pp. 313 - 315
Journal Article