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index medicus (292) 292
polyubiquitination (270) 270
humans (239) 239
animals (182) 182
ubiquitination (166) 166
ubiquitin (160) 160
cell biology (153) 153
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mice (106) 106
activation (99) 99
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phosphorylation (64) 64
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protein binding (57) 57
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binding (44) 44
proteolysis (44) 44
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enzymes (41) 41
immunology (41) 41
lysine - metabolism (40) 40
physiological aspects (38) 38
complex (37) 37
proteasome endopeptidase complex - metabolism (37) 37
cell line, tumor (34) 34
cancer (33) 33
pathway (33) 33
multidisciplinary sciences (32) 32
polyubiquitin - metabolism (32) 32
ubiquitin-proteasome system (32) 32
expression (31) 31
autophagy (30) 30
hela cells (30) 30
proteasome (30) 30
mice, knockout (29) 29
ubiquitin-conjugating enzymes - metabolism (29) 29
ubiquitin-protein ligases - genetics (29) 29
gene expression (28) 28
mutation (28) 28
amino acid sequence (27) 27
biophysics (27) 27
chains (27) 27
dna damage (27) 27
ligase (26) 26
biology (25) 25
inflammation (25) 25
protein transport (25) 25
ubiquitin ligase (25) 25
cells (24) 24
endocytosis (24) 24
intracellular signaling peptides and proteins - metabolism (24) 24
k11-linked polyubiquitination (24) 24
mice, inbred c57bl (24) 24
molecular sequence data (24) 24
oncology (24) 24
p53 (24) 24
analysis (23) 23
kinase (23) 23
nuclear proteins - metabolism (23) 23
ubiquitin - chemistry (23) 23
lysine (22) 22
ubiquitination - drug effects (22) 22
cell cycle (21) 21
female (21) 21
gene (21) 21
innate immunity (21) 21
mechanism (21) 21
recognition (21) 21
ubiquitination - physiology (21) 21
kinases (20) 20
macromolecular substances (20) 20
male (20) 20
nf-κb (20) 20
tumor suppressor protein p53 - metabolism (20) 20
ubiquitylation (20) 20
dna (19) 19
gene expression regulation (19) 19
genetic aspects (19) 19
inhibition (19) 19
models, molecular (19) 19
molecular biology (19) 19
nf-kappa b (19) 19
protein structure, tertiary (19) 19
ubiquitin-protein ligase (19) 19
life sciences (18) 18
nemo (18) 18
protein processing, post-translational (18) 18
signal transduction - drug effects (18) 18
down-regulation (17) 17
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Neuroscience Letters, ISSN 0304-3940, 06/2019, Volume 703, pp. 53 - 57
Characteristic neuropathological structures observed in Alzheimer’s disease, such as neurofibrillary tangles and dystrophic neurites of senile plaques, are... 
Ubiquitin | Immunohistochemistry | Tau | Linear polyubiquitination | Alzheimer
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2020, Volume 521, Issue 2, pp. 533 - 538
Retinoblastoma (RB) is the most common intraocular malignancy. The tumor propagation of RB is maintained by several core transcriptional regulators, including... 
Tumorigenesis | Retinoblastoma | Polyubiquitination | c-Myc | ZCCHC2
Journal Article
SCIENCE, ISSN 0036-8075, 05/2019, Volume 364, Issue 6441, pp. 651 - 651
Activation of tumor suppressors for the treatment of human cancer has been a long sought, yet elusive, strategy. PTEN is a critical tumor suppressive... 
UBIQUITINATION | GENE | E3 LIGASE WWP1 | MULTIDISCIPLINARY SCIENCES | INDOLE-3-CARBINOL | MECHANISMS | CONTINUUM | MODEL | CELL-SURVIVAL | POLYUBIQUITINATION | BREAST
Journal Article
New Phytologist, ISSN 0028-646X, 02/2018, Volume 217, Issue 3, pp. 995 - 1011
Journal Article
Cellular Signalling, ISSN 0898-6568, 07/2012, Volume 24, Issue 7, pp. 1381 - 1389
Protein kinases are important regulators of intracellular signal transduction pathways and play critical roles in diverse cellular processes. TAK1, a member of... 
Degradation | TNFα | TAK1 | Lys | linked polyubiquitination
Journal Article
by Kao, SH and Cheng, WC and Wang, YT and Wu, HT and Yeh, HY and Chen, YJ and Tsai, MH and Wu, KJ
CANCER RESEARCH, ISSN 0008-5472, 05/2019, Volume 79, Issue 10, pp. 2549 - 2563
Markers of cancer stemness predispose patients to tumor aggressiveness, drug and immunotherapy resistance, relapse, and metastasis. DDX17 is a cofactor of the... 
CELLS | DATABASE | ONCOLOGY | UBIQUITIN LIGASE | ACETYLATION | TRANSCRIPTION | RNA HELICASES | POLYUBIQUITINATION | MICROPROCESSOR
Journal Article
Cell, ISSN 0092-8674, 06/2009, Volume 137, Issue 6, pp. 1001 - 1004
Journal Article