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1. Full Text Switching antiplatelet therapy in real-world clinical practice
by Angiolillo, Dominick J
Cardiovascular revascularization medicine, ISSN 1553-8389, 12/2018, Volume 19, Issue 8, pp. 897 - 898
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2. Full Text Morphine interaction with prasugrel: a double-blind, cross-over trial in healthy volunteers
by Hobl, Eva-Luise and Hobl, Eva-Luise and Reiter, Birgit and Reiter, Birgit and Schoergenhofer, Christian and Schoergenhofer, Christian and Schwameis, Michael and Schwameis, Michael and Derhaschnig, Ulla and Derhaschnig, Ulla and Lang, Irene Marthe and Lang, Irene Marthe and Stimpfl, Thomas and Stimpfl, Thomas and Jilma, Bernd and Jilma, Bernd
Clinical research in cardiology, ISSN 1861-0684, 4/2016, Volume 105, Issue 4, pp. 349 - 355
Prasugrel | Medicine & Public Health | Drug interactions | Morphine | Platelet function tests | Cardiology | Vasodilator-stimulated phosphoprotein | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Purinergic P2Y Receptor Antagonists - administration & dosage | Humans | Male | Purinergic P2Y Receptor Antagonists - blood | Drug Monitoring - methods | Healthy Volunteers | Platelet Aggregation Inhibitors - blood | Young Adult | Purinergic P2Y Receptor Antagonists - adverse effects | Tandem Mass Spectrometry | Austria | Analgesics, Opioid - adverse effects | Drug Interactions | Biotransformation | Platelet Aggregation Inhibitors - administration & dosage | Platelet Function Tests | Chromatography, Liquid | Adult | Female | Platelet Aggregation - drug effects | Platelet Aggregation Inhibitors - pharmacokinetics | Prasugrel Hydrochloride - administration & dosage | Prasugrel Hydrochloride - pharmacokinetics | Platelet Aggregation Inhibitors - adverse effects | Double-Blind Method | Risk Assessment | Purinergic P2Y Receptor Antagonists - pharmacokinetics | Prasugrel Hydrochloride - adverse effects | Cross-Over Studies | Analgesics, Opioid - administration & dosage | Morphine - administration & dosage | Morphine - adverse effects | Prasugrel Hydrochloride - blood | Medical colleges | Metabolites | Vasodilators | Clinical trials | Liquid chromatography | Mass spectrometry | Index Medicus | Original Paper
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3. Full Text Morphine delays the onset of action of prasugrel in patients with prior history of ST-elevation myocardial infarction
by Thomas, Mark R and Morton, Allison C and Hossain, Rashed and Chen, Beining and Luo, Lei and Shahari, Nur Nazihah B. Md and Hua, Peng and Beniston, Richard G and Judge, Heather M and Storey, Robert F
Thrombosis and haemostasis, ISSN 0340-6245, 01/2016, Volume 116, Issue 7, pp. 96 - 102
Cellular Haemostasis and Platelets | Prasugrel | inhibitors | Morphine | Platelet reactivity | Antiplatelet medications | P2Y | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Humans | Middle Aged | Intestinal Absorption - drug effects | ST Elevation Myocardial Infarction - drug therapy | Male | ST Elevation Myocardial Infarction - blood | Cross-Over Studies | Platelet Aggregation Inhibitors - blood | Time Factors | Platelet Aggregation Inhibitors - administration & dosage | ST Elevation Myocardial Infarction - surgery | Aged | Platelet Aggregation - drug effects | Platelet Aggregation Inhibitors - pharmacokinetics | Prasugrel Hydrochloride - administration & dosage | Prasugrel Hydrochloride - pharmacokinetics | Morphine - administration & dosage | Morphine - adverse effects | Percutaneous Coronary Intervention | Prasugrel Hydrochloride - blood
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4. Full Text Crushed Prasugrel Tablets in Patients with STEMI Undergoing Primary Percutaneous Coronary Intervention the CRUSH Study
by Rollini, Fabiana and Franchi, Francesco and Hu, Jenny and Kureti, Megha and Aggarwal, Niti and Durairaj, Ashwin and Park, Yongwhi and Seawell, Michael and Cox-Alomar, Pedro and Zenni, Martin M and Guzman, Luis A and Suryadevara, Siva and Antoun, Patrick and Bass, Theodore A and Angiolillo, Dominick J
Journal of the American College of Cardiology, ISSN 0735-1097, 05/2016, Volume 67, Issue 17, pp. 1994 - 2004
crushed tablet | pharmacodynamic | pharmacokinetic | platelets | Prospective Studies | Tablets | Humans | Middle Aged | Male | ST Elevation Myocardial Infarction - therapy | Platelet Aggregation | Platelet Aggregation Inhibitors - blood | Receptors, Purinergic P2Y12 - blood | Platelet Aggregation Inhibitors - administration & dosage | Female | Platelet Aggregation Inhibitors - pharmacokinetics | Prasugrel Hydrochloride - administration & dosage | Prasugrel Hydrochloride - pharmacokinetics | Percutaneous Coronary Intervention | Prasugrel Hydrochloride - blood | Transluminal angioplasty | Medicine, Experimental | Medical research | Cardiology | Studies | Anticoagulants | Aspirin | Heart attacks | Blood platelets | Bioavailability | Acute coronary syndromes | Drug dosages | Index Medicus | Abridged Index Medicus
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5. Full Text A Multinational Trial of Prasugrel for Sickle Cell Vaso-Occlusive Events
by Heeney, Matthew M and Hoppe, Carolyn C and Abboud, Miguel R and Inusa, Baba and Kanter, Julie and Ogutu, Bernhards and Brown, Patricia B and Heath, Lori E and Jakubowski, Joseph A and Zhou, Chunmei and Zamoryakhin, Dmitry and Agbenyega, Tsiri and Colombatti, Raffaella and Hassab, Hoda M and Nduba, Videlis N and Oyieko, Janet N and Robitaille, Nancy and Segbefia, Catherine I and Rees, David C and DOVE Investigators
The New England journal of medicine, ISSN 0028-4793, 02/2016, Volume 374, Issue 7, pp. 625 - 635
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Peripheral Vascular Diseases - prevention & control | Acute Chest Syndrome - etiology | Double-Blind Method | Pain - prevention & control | Administration, Oral | Anemia, Sickle Cell - complications | Humans | Child, Preschool | Male | Anemia, Sickle Cell - drug therapy | Prasugrel Hydrochloride - adverse effects | Prasugrel Hydrochloride - therapeutic use | Peripheral Vascular Diseases - etiology | Adolescent | Pain - etiology | Female | Hemorrhage - chemically induced | Platelet Aggregation Inhibitors - therapeutic use | Acute Chest Syndrome - prevention & control | Child | Platelet Aggregation Inhibitors - adverse effects | Care and treatment | Sickle cell anemia | Occlusion | Anemia | Clinical trials | Patients | Hemorrhage | Thrombosis | Pain | Blood platelets | Cell adhesion | Children | Sickle cell disease | Drug therapy | Adolescents | Index Medicus | Abridged Index Medicus
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6. Full Text Effect of 1-Month Dual Antiplatelet Therapy Followed by Clopidogrel vs 12-Month Dual Antiplatelet Therapy on Cardiovascular and Bleeding Events in Patients Receiving PCI: The STOPDAPT-2 Randomized Clinical Trial
by Watanabe, Hirotoshi and Domei, Takenori and Morimoto, Takeshi and Natsuaki, Masahiro and Shiomi, Hiroki and Toyota, Toshiaki and Ohya, Masanobu and Suwa, Satoru and Takagi, Kensuke and Nanasato, Mamoru and Hata, Yoshiki and Yagi, Masahiro and Suematsu, Nobuhiro and Yokomatsu, Takafumi and Takamisawa, Itaru and Doi, Masayuki and Noda, Toshiyuki and Okayama, Hideki and Seino, Yoshitane and Tada, Tomohisa and Sakamoto, Hiroki and Hibi, Kiyoshi and Abe, Mitsuru and Kawai, Kazuya and Nakao, Koichi and Ando, Kenji and Tanabe, Kengo and Ikari, Yuji and Hanaoka, Keiichi Igarashi and Morino, Yoshihiro and Kozuma, Ken and Kadota, Kazushige and Furukawa, Yutaka and Nakagawa, Yoshihisa and Kimura, Takeshi and STOPDAPT-2 Investigators and for the STOPDAPT-2 Investigators
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 06/2019, Volume 321, Issue 24, pp. 2414 - 2427
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Drug-Eluting Stents | Drug Administration Schedule | Humans | Middle Aged | Male | Prasugrel Hydrochloride - adverse effects | Prasugrel Hydrochloride - therapeutic use | Aspirin - adverse effects | Female | Aged | Aspirin - therapeutic use | Clopidogrel - adverse effects | Hemorrhage - chemically induced | Clopidogrel - therapeutic use | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Percutaneous Coronary Intervention | Purinergic P2Y Receptor Antagonists - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Aggregation | Aspirin | Dosage and administration | Blood platelets | Cardiovascular diseases | Drug therapy | Myocardial infarction | Cerebral infarction | Therapy | Surgical implants | Stroke | Clinical trials | Drug delivery | Criteria | Thrombosis | Hemorrhage | Patients | Bleeding | Ischemia | Implants | Clopidogrel | Thromboembolism | Stents | Index Medicus | Abridged Index Medicus | Original Investigation | Research
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7. Full Text Pharmacokinetics and pharmacodynamics of oral P2Y12 inhibitors during the acute phase of a myocardial infarction: A systematic review
by Khan, Nazish and Cox, Anthony R and Cotton, James M
Thrombosis research, ISSN 0049-3848, 2016, Volume 143, pp. 141 - 148
Hematology, Oncology and Palliative Medicine | Prasugrel | P2Y12 inhibitors | Aspirin | ST elevation myocardial infarction | Platelet function assays | Primary percutaneous coronary intervention | STEMI | Clopidogrel | Ticagrelor | Inhibition of platelet activity (IPA) | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Prasugrel Hydrochloride - pharmacology | Adenosine - pharmacokinetics | Purinergic P2Y Receptor Antagonists - administration & dosage | Ticlopidine - pharmacology | Ticlopidine - therapeutic use | Humans | Adenosine - therapeutic use | Platelet Aggregation Inhibitors - administration & dosage | Platelet Aggregation Inhibitors - pharmacology | Ticlopidine - administration & dosage | Platelet Aggregation Inhibitors - pharmacokinetics | Ticlopidine - pharmacokinetics | Prasugrel Hydrochloride - administration & dosage | Platelet Aggregation Inhibitors - therapeutic use | Prasugrel Hydrochloride - pharmacokinetics | Purinergic P2Y Receptor Antagonists - therapeutic use | Myocardial Infarction - surgery | Purinergic P2Y Receptor Antagonists - pharmacology | Administration, Oral | Purinergic P2Y Receptor Antagonists - pharmacokinetics | Adenosine - pharmacology | Adenosine - administration & dosage | Ticlopidine - analogs & derivatives | Prasugrel Hydrochloride - therapeutic use | Myocardial Infarction - drug therapy | Adenosine - analogs & derivatives | Percutaneous Coronary Intervention | Heart attack | Index Medicus
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8. Full Text Long-term dual antiplatelet therapy for secondary prevention of cardiovascular events in the subgroup of patients with previous myocardial infarction: A collaborative meta-analysis of randomized trials
by Udell, Jacob A and Bonaca, Marc P and Collet, Jean-Philippe and Lincoff, A. Michael and Kereiakes, Dean J and Costa, Francesco and Lee, Cheol Whan and Mauri, Laura and Valgimigli, Marco and Park, Seung-Jung and Montalescot, Gilles and Sabatine, Marc S and Braunwald, Eugene and Bhatt, Deepak L
European heart journal, ISSN 0195-668X, 01/2016, Volume 37, Issue 4, pp. 390 - 399
Myocardial infarction | Prasugrel | Clopidogrel | Stable coronary heart disease | Ticagrelor | Dual antiplatelet therapy | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Humans | Middle Aged | Treatment Outcome | Long-Term Care | Adenosine - administration & dosage | Secondary Prevention - methods | Ticlopidine - analogs & derivatives | Randomized Controlled Trials as Topic | Young Adult | Adenosine - analogs & derivatives | Platelet Aggregation Inhibitors - administration & dosage | Ticlopidine - administration & dosage | Adult | Aged | Myocardial Infarction - prevention & control | Prasugrel Hydrochloride - administration & dosage | Drug Therapy, Combination | Index Medicus
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9. Full Text Prasugrel in critically ill patients
by Schoergenhofer, Christian and Hobl, Eva-Luise and Staudinger, Thomas and Speidl, Walter S and Heinz, Gottfried and Siller-Matula, Jolanta and Zauner, Christian and Reiter, Birgit and Kubica, Jacek and Jilma, Bernd
Thrombosis and haemostasis, ISSN 0340-6245, 06/2017, Volume 117, Issue 8, pp. 1582 - 1587
Cellular Haemostasis and Platelets | Antiplatelet drugs | Pharmacodynamics | Pharmacokinetics | Intensive care unit | Platelet function | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Activation, Metabolic | Humans | Middle Aged | Critical Illness | Male | Microfilament Proteins - blood | Drug Monitoring - methods | Platelet Aggregation Inhibitors - blood | Austria | Phosphoproteins - blood | Platelet Aggregation Inhibitors - administration & dosage | Platelet Function Tests | Female | Platelet Aggregation - drug effects | Platelet Aggregation Inhibitors - pharmacokinetics | Prasugrel Hydrochloride - administration & dosage | Blood Platelets - drug effects | Prasugrel Hydrochloride - pharmacokinetics | Drug Resistance | Platelet Aggregation Inhibitors - adverse effects | Cell Adhesion Molecules - blood | Treatment Outcome | Prasugrel Hydrochloride - adverse effects | Biomarkers - blood | Blood Platelets - metabolism | Prasugrel Hydrochloride - blood | pharmacokinetics | intensive care unit | platelet function | pharmacodynamics
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10. Full Text Guided de-escalation of antiplatelet treatment in patients with acute coronary syndrome undergoing percutaneous coronary intervention (TROPICAL-ACS): a randomised, open-label, multicentre trial
by Sibbing, Dirk and Aradi, Dániel and Jacobshagen, Claudius and Gross, Lisa and Trenk, Dietmar and Geisler, Tobias and Orban, Martin and Hadamitzky, Martin and Merkely, Béla and Kiss, Róbert Gábor and Komócsi, András and Dézsi, Csaba A and Holdt, Lesca and Felix, Stephan B and Parma, Radoslaw and Klopotowski, Mariusz and Schwinger, Robert H G and Rieber, Johannes and Huber, Kurt and Neumann, Franz-Josef and Koltowski, Lukasz and Mehilli, Julinda and Huczek, Zenon and Massberg, Steffen and Parma, Radoslaw and Parma, Zofia and Lesiak, Maciej and Komosa, Anna and Huczek, Zenon and Koltowski, Lukasz and Kowara, Michal and Rymuza, Bartosz and Klopotowski, Mariusz and Malek, Lukasz and Aradi, Daniel and Veress, Gábor and Dézsi, András Döme and Merkely, Béla and Lux, Árpád and Kiss, Róbert Gábor and Papp, Judit and Kovács, Andrea and Dézsi, Csaba András and Amer, Sayour and Ruzsa, Zoltán and Róna, Szilárd and Komócsi, András and Ili, Renáta and Ungi, Imre and Nagy, Ferenc and Zweiker, Robert and Tóth-Gayor, Gábor and Huber, Kurt and Haller, Paul and von Scheidt, Wolfgang and Blüthgen, Andreas and Neumann, Franz-Josef and Trenk, Dietmar and Leggewie, Stefan and Kreider-Stempfle, Hans Ulrich and Remp, Thomas and Kara, Kaffer and Mügge, Andreas and Wutzler, Alexander and Fichtlscherer, Stephan and Zeiher, Andreas M and Seeger, Florian and Hinterseer, Martin and König, Andreas and Lederle, Susanne and Jacobshagen, Claudius and Czepluch, Frauke and Maier, Lars and Schillinger, Wolfgang and Sossalla, Samuel and Hummel, Astrid and Felix, Stephan and Karakas, Mahir and Sydow, Karsten and Rudolph, Tanja and Halbach, Marcel and Gori, Tommaso and Münzel, Thomas and May, Andreas and Gerstenberg, Carsten-Manuel and Pilecky, David and Rieber, Johannes and Deichstetter, Markus and Sibbing, Dirk and Mehilli, Julinda and Gross, Lisa and Kääb, Stefan and Löw, Anja and Orban, Martin and Orban, Matthias and Sattler, Stefan and Deuschl, Sabine and Teupser, Daniel and Holdt, Lesca and Mudra, Harald and ... and TROPICAL-ACS Investigators
The Lancet (British edition), ISSN 0140-6736, 10/2017, Volume 390, Issue 10104, pp. 1747 - 1757
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Myocardial Infarction - epidemiology | Acute Coronary Syndrome - epidemiology | Drug Administration Schedule | Hemorrhage - epidemiology | Humans | Middle Aged | Europe - epidemiology | Male | Prasugrel Hydrochloride - adverse effects | Ticlopidine - analogs & derivatives | Platelet Aggregation Inhibitors - administration & dosage | Platelet Function Tests | Ticlopidine - adverse effects | Ticlopidine - administration & dosage | Acute Coronary Syndrome - therapy | Clopidogrel | Female | Stroke - epidemiology | Hemorrhage - chemically induced | Prasugrel Hydrochloride - administration & dosage | Drug Monitoring | Percutaneous Coronary Intervention | Platelet Aggregation Inhibitors - adverse effects | Transluminal angioplasty | Care and treatment | Coronary heart disease | Cardiac patients | Analysis | Anticoagulants | Heart attacks | Blood platelets | Angioplasty | Clinical trials | Acute coronary syndromes | Drug therapy | Patients | Evidence-based medicine | Clinical outcomes | Myocardial infarction | Intervention | Bleeding | Consortia | Randomization | Motivation | Inhibition | Cerebral infarction | Stroke | Test procedures | Health risks | Thrombosis | Coronary vessels | Biomarkers | Infarction | Cardiovascular diseases | Platelets | Index Medicus | Abridged Index Medicus
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