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Gut, ISSN 0017-5749, 09/2018, Volume 67, Issue 9, pp. 1683 - 1691
bile acid metabolism | primary sclerosing cholangitis | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Animal models | Glucagon | Liver | Microbiomes | Gallbladder diseases | Homeostasis | Biochemistry | Pruritus | Proteins | Microbiota | Intestine | Rodents | Gastroenterology | Colon | Intestinal microflora | Resins | Digestive tract | Glucagon-like peptide 1 | Enzyme-linked immunosorbent assay | Phenotypes | Excretion | Statistical analysis | Bile acids | Digestive system | Cholangitis | Histology | Inflammation | Gene expression | Bile duct | Acids | Hepatocytes | Fibrosis | Protein expression | Cholestasis | Bile | Index Medicus | Abridged Index Medicus | 2312 | 1506 | Hepatology | Gastroenterology and Hepatology | Gastroenterologi
Journal Article
Biochimica et biophysica acta. Molecular basis of disease, ISSN 0925-4439, 04/2018, Volume 1864, Issue 4, pp. 1345 - 1355
Primary biliary cholangitis | Intrahepatic cholestasis of pregnancy | Primary sclerosing cholangitis | Bile acids | Cirrhotic cardiomyopathy | Ursodeoxycholic acid | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cholagogues and Choleretics - pharmacology | Bile Acids and Salts - blood | Cholestasis, Intrahepatic - blood | Pregnancy Complications - blood | Prevalence | Apoptosis - drug effects | Humans | Bile Acids and Salts - chemistry | Cardiomyopathies - prevention & control | Cholestasis, Intrahepatic - drug therapy | Cardiomyopathies - etiology | Cholagogues and Choleretics - therapeutic use | Cholangitis - drug therapy | Ursodeoxycholic Acid - therapeutic use | Cholangitis - complications | Female | Cholangitis - metabolism | Pregnancy Complications - metabolism | Cholestasis, Intrahepatic - complications | Heart - physiopathology | Arrhythmias, Cardiac - prevention & control | Cardiomyopathies - blood | Maternal-Fetal Exchange | Liver Cirrhosis, Biliary - drug therapy | Bile Acids and Salts - metabolism | Arrhythmias, Cardiac - etiology | Cholangitis - blood | Pregnancy Complications - drug therapy | Pregnancy | Myocytes, Cardiac - pathology | Ursodeoxycholic Acid - pharmacology | Cardiomyopathies - epidemiology | Cholestasis, Intrahepatic - metabolism | Heart - drug effects | Hydrophobic and Hydrophilic Interactions | Hemodynamics - drug effects | Liver Cirrhosis, Biliary - complications | Liver Cirrhosis, Biliary - blood | Liver Cirrhosis, Biliary - metabolism | Index Medicus
Journal Article
Journal of hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 1, pp. 155 - 168
Gastroenterology and Hepatology | Gallstones | Liver cancer | Bile acids | Fatty liver disease | Cholestasis | Liver regeneration | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Animals | Carrier Proteins - metabolism | Cholestasis - metabolism | Membrane Glycoproteins - metabolism | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Liver Diseases - metabolism | Liver Regeneration - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Corticosteroids | Glucagon | Calcifediol | Ursodiol | Deoxycholic acid | Epidermal growth factor | Vitamin D | Physiological aspects | Fibroblast growth factors | Alfacalcidol | Index Medicus | IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6 | PFIC, progressive familial intrahepatic cholestasis | TNFα, tumor necrosis factor α | 3 (human) | SRC2, p160 steroid receptor coactivator | NAFLD, non-alcoholic fatty liver disease | BA, bile acid | bile acid receptor | 8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5 | UDCA, ursodeoxycholic acid | LRH-1 (NR5A2), liver receptor homolog-1 | LCA, lithocholic acid | LXRα (NR1H3), liver X receptor alpha | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | OSTαβ, organic solute transporter alpha | ABCG5 | AMPK, AMP activated protein kinase | NASH, non-alcoholic steatohepatitis | SHP (NR0B2), short heterodimer partner | OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2 | EGFR, epidermal growth factor receptor | IL6, interleukin 6 | TGR5, G protein-coupled bile acid receptor | PH, partial hepatectomy | AE2, anion exchanger 2 | PSC, primary sclerosing cholangitis | OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1 | RARα (NR1B1), retinoic acid receptor alpha | GLP-1, glucagon like peptide 1 | VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents | MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2 | NTCP (SLC10A1), sodium | CAR (NR1I3), constitutive androstane receptor | taurocholate cotransporting polypeptide, solute carrier family 10, member 1 | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | GR (NR3C1), glucocorticoid receptor | Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer | 19, fibroblast growth factor 15 | Mdr2 | ICP, intrahepatic cholestasis of pregnancy | BRIC, benign recurrent intrahepatic cholestasis | OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3 | MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3 | beta | MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1 | norUDCA, norursodeoxycholic acid | 6-ECDCA, 6-ethylchenodeoxycholic acid | FXR (NR1H4), farnesoid X receptor | BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2 | HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha | PBC, primary biliary cirrhosis | MDR3 (ABCB4), multidrug resistance protein 2 (rodents) | HNF1α, hepatocyte nuclear factor 1 alpha | NR, nuclear receptor | FGF15 | RXRα (NR2B1), retinoid X receptor alpha | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | HCC, hepatocellular carcinoma | MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4 | TPN, total parenteral nutrition
Journal Article
Proteins, structure, function, and bioinformatics, ISSN 0887-3585, 03/2016, Volume 84, Issue 3, pp. 316 - 331
structural genomics | secondary bile acid | gut microbe mediated human metabolite | gut microbes | nuclear transport factor‐2 superfamily | secondary bile acid synthesis | primary bile acid | 7α‐dehyroxylation | bile acid 7α‐dehydratase | Bile acid 7α-dehydratase | Secondary bile acid | Nuclear transport factor-2 superfamily | Primary bile acid | 7α-dehyroxylation | Secondary bile acid synthesis | Gut microbe mediated human metabolite | Structural genomics | Gut microbes | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Catalytic Domain | Mutagenesis, Site-Directed | Hydroxylation | Protein Structure, Secondary | Humans | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Crystallography, X-Ray | Cholic Acids - biosynthesis | Clostridium - enzymology | Hydrogen Bonding | Cholic Acids - chemistry | Protein Binding | Molecular Docking Simulation | Structural Homology, Protein | Hydro-Lyases - chemistry | Hydro-Lyases - genetics | Kinetics | Amino Acid Substitution | Index Medicus | nuclear transport factor-2 superfamily | bile acid 7α-dehydratase
Journal Article
Current opinion in lipidology, ISSN 0957-9672, 02/2012, Volume 23, Issue 1, pp. 43 - 55
SMALL HETERODIMER PARTNER | glucose | CORONARY-ARTERY DISEASE | GLYCEMIC CONTROL | bile acid sequestrants | UMCG Approved | hypercholesterolemia | ORPHAN NUCLEAR RECEPTOR | DENSITY-LIPOPROTEIN CHOLESTEROL | GLUCAGON-LIKE PEPTIDE-1 | bile acids | PRIMARY HYPERCHOLESTEROLEMIA | FARNESOID-X-RECEPTOR | COLESEVELAM HYDROCHLORIDE | TYPE-2 DIABETES-MELLITUS | energy metabolism | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Anion Exchange Resins - pharmacology | Dyslipidemias - drug therapy | Cholestyramine Resin - therapeutic use | Humans | Bile Acids and Salts - metabolism | Clinical Trials as Topic | Animals | Anticholesteremic Agents - therapeutic use | Cholestyramine Resin - pharmacology | Anion Exchange Resins - therapeutic use | Diabetes Mellitus, Type 2 - drug therapy | Anticholesteremic Agents - pharmacology | Energy Metabolism - drug effects | Index Medicus
Journal Article
Journal of hepatology, ISSN 0168-8278, 09/2017, Volume 67, Issue 3, pp. 619 - 631
Bile ducts | Cholangitis | Primary biliary cholangitis | Bile secretion | Primary sclerosing cholangitis | Bile canaliculus | Cholangiopathies | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Carrier Proteins - physiology | Liver Cirrhosis - etiology | Liver - pathology | Humans | ATP Binding Cassette Transporter, Sub-Family B - physiology | ATP Binding Cassette Subfamily B Member 11 - physiology | Autophagy | Membrane Glycoproteins - physiology | Animals | Cholestasis - etiology | Mice | Bile Acids and Salts - physiology | Apoptosis | Liver diseases | Bile acids | Acids | Cell death | Gallbladder diseases | Bile | Index Medicus
Journal Article