X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
pristimerin (106) 106
index medicus (48) 48
apoptosis (47) 47
triterpenes - pharmacology (33) 33
humans (32) 32
pharmacology & pharmacy (25) 25
celastraceae (21) 21
oncology (21) 21
animals (18) 18
triterpenes - chemistry (16) 16
biochemistry & molecular biology (14) 14
cell line, tumor (14) 14
cancer (13) 13
chemistry, medicinal (13) 13
proteins (13) 13
antineoplastic agents - pharmacology (12) 12
inflammation (12) 12
plant sciences (12) 12
triterpenes (12) 12
apoptosis - drug effects (11) 11
cells (11) 11
kinases (11) 11
mice (11) 11
nf-kappa-b (11) 11
cell proliferation - drug effects (10) 10
male (10) 10
tingenone (10) 10
triterpenes - isolation & purification (10) 10
triterpenoids (10) 10
angiogenesis (9) 9
breast cancer (9) 9
cell cycle (9) 9
chemotherapy (9) 9
female (9) 9
growth (9) 9
in-vitro (9) 9
cancer therapies (8) 8
death (8) 8
flow cytometry (8) 8
health aspects (8) 8
maytenus - chemistry (8) 8
pathway (8) 8
signal transduction - drug effects (8) 8
analysis (7) 7
article (7) 7
cancer cells (7) 7
care and treatment (7) 7
celastrol (7) 7
chemistry, multidisciplinary (7) 7
chemistry, organic (7) 7
cytotoxic activity (7) 7
induction (7) 7
nf-kappa b - metabolism (7) 7
nf-κb (7) 7
plants (7) 7
rats (7) 7
ros (7) 7
terpenoids (7) 7
toxicology (7) 7
activation (6) 6
articles (6) 6
cell death (6) 6
cytotoxicity (6) 6
development and progression (6) 6
drug screening assays, antitumor (6) 6
immunoglobulins (6) 6
inhibition (6) 6
mice, inbred balb c (6) 6
mice, nude (6) 6
molecular structure (6) 6
nf-kappa b (6) 6
oxidative stress (6) 6
akt (5) 5
antineoplastic agents - chemistry (5) 5
antineoplastic agents, phytogenic - pharmacology (5) 5
biosynthesis (5) 5
cancer-cells (5) 5
cell biology (5) 5
cell growth (5) 5
cell movement - drug effects (5) 5
colorectal cancer (5) 5
dose-response relationship, drug (5) 5
gene expression regulation, neoplastic - drug effects (5) 5
genetic aspects (5) 5
integrative & complementary medicine (5) 5
invasion (5) 5
maytenus (5) 5
metastasis (5) 5
migration (5) 5
mitochondria (5) 5
pharmacology (5) 5
phosphorylation (5) 5
plant roots (5) 5
plant roots - chemistry (5) 5
proliferation (5) 5
quinone (5) 5
reactive oxygen species - metabolism (5) 5
scutioides (5) 5
structure-activity relationship (5) 5
triterpene (5) 5
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Phytomedicine, ISSN 0944-7113, 02/2018, Volume 40, pp. 140 - 147
Colorectal cancer (CRC) is one of the most common malignancies associated with high mortality rate worldwide. We previously reported that pristimerin inhibits... 
NF-кB | Pristimerin | Colorectal cancer | HCT-116 cells
Journal Article
Current Cancer Drug Targets, ISSN 1568-0096, 01/2016, Volume 16, Issue 1, pp. 100 - 108
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2019
AbstractObjectivePlatinum compounds have been widely used as a primary treatment for many types of cancer. However, resistance is the major cause of... 
Hematology, Oncology, and Palliative Medicine | Obstetrics and Gynecology
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2016, Volume 39, Issue 1, pp. 97 - 103
This paper describes the ultrasound-assisted extraction (UAE) of pristimerin from Celastrus orbiculatus. Methanol was the most effective for pristimerin... 
Journal Article
International Immunopharmacology, ISSN 1567-5769, 06/2018, Volume 59, pp. 31 - 39
Pristimerin (Pris) is a triterpenoid derivative obtained from Celastraceae and Hippocrateaceae families. This compound has been extensively tested for its... 
Lipopolysaccharide | Pristimerin | Inflammation | Lung | Apoptosis | CELLS | INHIBITING INFLAMMATION | PATHWAY | PHARMACOLOGY & PHARMACY | TISSUES | IMMUNOLOGY | RESPIRATORY-DISTRESS-SYNDROME | Antioxidants | Acute respiratory distress syndrome | Drugstores | Interleukins | Mitogens | Pharmacy
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 02/2019, Volume 299, pp. 1 - 7
Gliomas are among the most frequent types of primary malignancies in the central nervous system. The main treatment for glioma includes surgical resection... 
Glioma | Mahanine | Invasion | Apoptosis | PI3K/AKT | PRISTIMERIN | TARGET | ACTIVATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | BRAF | ROS | PLANTS | PHARMACOLOGY & PHARMACY | TOXICOLOGY
Journal Article
Helvetica Chimica Acta, ISSN 0018-019X, 06/2013, Volume 96, Issue 6, pp. 1046 - 1054
In continuation of our work on Maytenus salicifolia, we report herein the isolation and structural elucidation of two new compounds, salicassin (1), a... 
Salicassin | Maytenus salicifolia | Triterpenoids | Pristimerin, 16β-hydroxy | Cytotoxic activity
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 03/2019, Volume 231, pp. 516 - 524
(Miers) A. C. Smith (family Celastraceae) is a traditional medicinal plant found in the Amazon Rainforest known as “miraruíra”, "cipó-miraruíra" or “panu” and... 
5-fluorouracil | Salacia impressifolia | Celastraceae | Pristimerin | Anti-leukemia | HL-60 | Tingenone | 22-hydroxytingenone | Doxorubicin | APOPTOSIS | CELLS | CHEMISTRY, MEDICINAL | SAFETY | KAPPA-B | TRITERPENES | CYTOTOXIC ACTIVITY | PLANT SCIENCES | INTEGRATIVE & COMPLEMENTARY MEDICINE | PHARMACOLOGY & PHARMACY
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2012, Volume 13, Issue 4, pp. 1097 - 1104
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2016
This paper describes the ultrasound-assisted extraction (UAE) of pristimerin from Celastrus orbiculatus. Methanol was the most effective for pristimerin... 
pristimerin | Celastrus orbiculatus | response surface methodology | ultrasound-assisted extraction | Optimization
Journal Article
Molecules, 06/2012, Volume 17, Issue 6, pp. 6854 - 6868
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 2013, Volume 36, Issue 2, pp. 316 - 325
Pristimerin is a naturally occurring triterpenoid that causes cytotoxicity in several cancer cell lines. However, the mechanism of action for the cytotoxic... 
Journal Article
by Wu, HY and Li, L and Ai, ZD and Yin, JY and Chen, L
ONCOLOGY LETTERS, ISSN 1792-1074, 03/2019, Volume 17, Issue 3, pp. 3017 - 3025
Pristimerin is an active compound isolated from the traditional Chinese herbs Celastraceae and Hippocrateaceae. It has been reported to exert antitumor effects... 
CANCER-CELLS | pristimerin | proliferation | ONCOLOGY | antitumor | GROWTH | DRUGS | apoptosis | oral squamous cell carcinoma | NF-KAPPA-B | CYCLE
Journal Article
PHYTOMEDICINE, ISSN 0944-7113, 02/2018, Volume 40, pp. 140 - 147
Background: Colorectal cancer (CRC) is one of the most common malignancies associated with high mortality rate worldwide. We previously reported that... 
MIGRATION | TARGET | APOPTOSIS | P65 PHOSPHORYLATION | ACTIVATION | CHEMISTRY, MEDICINAL | CYCLOOXYGENASE-2 | Colorectal cancer | TRANSCRIPTION | Pristimerin | ALPHA KINASE | PLANT SCIENCES | NF-kappa B | INTEGRATIVE & COMPLEMENTARY MEDICINE | INFLAMMATION | PHARMACOLOGY & PHARMACY | HCT-116 cells | INSIGHTS
Journal Article
CURRENT CANCER DRUG TARGETS, ISSN 1568-0096, 2017, Volume 17, Issue 2, pp. 100 - 108
Pristimerin, a natural triterpenoid isolated form Celastrus and Maytenus spp, has been shown to possess a variety of biological and pharmacological effects.... 
natural compounds | OXIDATIVE STRESS | SIGNALING PATHWAYS | MAYTENUS-ILICIFOLIA | TUMOR ANGIOGENESIS | IN-VITRO | Antitumor agents | NF-kappa B | pristimerin | ONCOLOGY | QUINONEMETHIDE TRITERPENES | pharmacological effects | FATTY-ACID SYNTHASE | NF-KAPPA-B | UBIQUITIN-PROTEASOME PATHWAY | PANCREATIC-CANCER CELLS
Journal Article
Phytomedicine, ISSN 0944-7113, 03/2018, Volume 42, pp. 164 - 171
Pristimerin is a quinonemethide triterpenoid with anti-cancer, anti-angiogenic, anti-inflammatory and anti-protozoal activity. However, the therapeutic role of... 
NF-κB | Pristimerin | FOXO3a | Colitis-associated colon cancer | Cell cycle | Apoptosis | CELLS | CHEMISTRY, MEDICINAL | TRANSCRIPTION | PLANT SCIENCES | MOLECULAR TARGETS | NF-kappa B | INTEGRATIVE & COMPLEMENTARY MEDICINE | INFLAMMATION | PHARMACOLOGY & PHARMACY
Journal Article
Journal Article
World Chinese Journal of Digestology, ISSN 1009-3079, 03/2016, Volume 24, Issue 7, pp. 1064 - 1069
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 07/2019, Volume 120, Issue 7, pp. 12002 - 12009
Journal Article
Medicines (Basel, Switzerland), ISSN 2305-6320, 03/2019, Volume 6, Issue 1, p. 36
: Quinonemethide triterpenoids, known as celastroloids, constitute a relatively small group of biologically active compounds restricted to the Celastraceae... 
Maytenus chiapensis | HPLC-PDA | pristimerin | tingenone | Celastraceae | quinonemethide triterpenoids
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.