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Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 06/2013, Volume 48, Issue 6, pp. 733 - 741
Journal Article
Journal Article
Journal of Endodontics, ISSN 0099-2399, 07/2019, Volume 45, Issue 7, pp. 873 - 881
During dental pulp healing, progenitor cells migrate to the injured site. This study investigated the effect of iloprost (an exogenous prostacyclin [PGI ]) on... 
dental pulp | prostacyclin analog | wound healing | iloprost | matrix metalloproteinase 9 | Cell migration | MMP-2 | DENTISTRY, ORAL SURGERY & MEDICINE | BLOOD-FLOW | EXPRESSION | Enzymes | Iloprost | RNA | Analysis | Genes | Genetic research | Prostacyclin | Gene expression | Protein kinases | Cells
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 01/2019, Volume 27, Issue 2, pp. 338 - 342
Isocarbacyclin is a valuable synthetic analogue of prostacyclin with potential neuroprotective effects for the treatment of ischemic stroke. Herein, we... 
Neuroprotective | Stroke | Synthesis | Isocarbacyclin | Analogues | CHEMISTRY, MEDICINAL | LIPID MICROSPHERES | THROMBOSIS | ALKYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | REPERFUSION | NEURONAL DAMAGE | PROSTACYCLIN RECEPTOR | CLINPROST | THERAPY | LIGAND | Index Medicus
Journal Article
Journal Article
Chest, ISSN 0012-3692, 08/2004, Volume 126, Issue 2, pp. 420 - 427
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2007, Volume 360, Issue 4, pp. 821 - 827
Journal Article
ANNALS OF THE RHEUMATIC DISEASES, ISSN 0003-4967, 12/2012, Volume 71, Issue 12, pp. 2044 - 2050
Objective Among pleiotropic effects, the capacity of prostaglandin I-2 (PGI(2)) analogues to affect adaptive immunity remains poorly characterised. The purpose... 
PROSTANOID RECEPTORS | CYTOKINE PRODUCTION | DENDRITIC CELLS | PROSTACYCLIN ANALOG | ILOPROST THERAPY | INTERLEUKIN 22 | ALLERGIC LUNG INFLAMMATION | CD4(+) T-CELLS | RAYNAUDS-PHENOMENON | RHEUMATOLOGY | HUMAN MONOCYTES
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 2004, Volume 102, Issue 2, pp. 139 - 153
Prostacyclin and its analogues (prostanoids) are potent vasodilators and possess antithrombotic and antiproliferative properties. All of these properties help... 
VASODILATORY RESPONSE | ARTERIAL-HYPERTENSION | AEROSOLIZED PROSTACYCLIN | ACUTE LUNG INJURY | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | PLACEBO-CONTROLLED TRIAL | CONTINUOUS INTRAVENOUS EPOPROSTENOL | LONG-TERM TREATMENT | INHALED NITRIC-OXIDE | RESPIRATORY-DISTRESS-SYNDROME
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 05/2019, Volume 60, Issue 22, pp. 1467 - 1470
A three-component coupling procedure was developed to construct the entire prostaglandin (PG) skeleton under HMPA-free and stoichiometric conditions a... 
Three-component prostaglandin synthesis | HMPA-free | Lithium enolate/dimethylzinc/organotriflate system | Organozincate conjugate addition | Mono-alkylation | TRIPLY CONVERGENT SYNTHESIS | ALKYLATION | CHEMISTRY, ORGANIC | RECEPTOR | Prostaglandins | Prostacyclin
Journal Article
Journal Article
Prostaglandins, Leukotrienes & Essential Fatty Acids, ISSN 0952-3278, 04/2015, Volume 95, p. 19
In this study, the inhibitory profiles of the prostacyclin analogues treprostinil and naxaprostene on several isolated smooth muscle preparations have been... 
Prostacyclin
Journal Article
Circulation Research, ISSN 0009-7330, 07/2010, Volume 107, Issue 2, pp. 252 - 262
RATIONALE:Mutations in the bone morphogenetic protein type II receptor (BMPR-II) are responsible for the majority of cases of heritable pulmonary arterial... 
cyclic adenosine 5'-monophosphate | inhibitor of DNA binding protein | prostacyclin | BMP type II receptor | Smad1 phosphorylation | CARDIAC & CARDIOVASCULAR SYSTEMS | cyclic adenosine 5 '-monophosphate | BONE MORPHOGENETIC PROTEIN | RECEPTOR | BMPR-II | LOOP-HELIX PROTEINS | GROWTH-FACTOR-BETA | THERAPY | GENE | GERMLINE MUTATIONS | PERIPHERAL VASCULAR DISEASE | HYPERTENSION | HEMATOLOGY | EXPRESSION | Up-Regulation | Antihypertensive Agents - pharmacology | Phosphorylation | Iloprost - pharmacology | Muscle, Smooth, Vascular - metabolism | Humans | Monocrotaline | Myocytes, Smooth Muscle - pathology | Male | Bone Morphogenetic Protein 4 - metabolism | Hypertension, Pulmonary - chemically induced | Pulmonary Artery - metabolism | Transfection | RNA Interference | Smad5 Protein - metabolism | Epoprostenol - pharmacology | Hypertension, Pulmonary - drug therapy | Myocytes, Smooth Muscle - drug effects | Cyclic AMP - metabolism | Myocytes, Smooth Muscle - metabolism | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Cyclic AMP-Dependent Protein Kinases - metabolism | Promoter Regions, Genetic | Bone Morphogenetic Protein Receptors, Type II - genetics | Cells, Cultured | Rats | Hypertension, Pulmonary - genetics | Smad Proteins - genetics | Hypertension, Pulmonary - metabolism | Pulmonary Artery - drug effects | Inhibitor of Differentiation Protein 1 - metabolism | Rats, Sprague-Dawley | Epoprostenol - analogs & derivatives | Muscle, Smooth, Vascular - pathology | Animals | Inhibitor of Differentiation Protein 1 - genetics | Smad1 Protein - metabolism | Cell Proliferation - drug effects | Smad6 Protein - metabolism | Mutation | Hypertension, Pulmonary - pathology | Smad Proteins - metabolism | Pulmonary Artery - pathology | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, pp. e98483 - e98483
Previous studies showed that prostacyclin inhibited fibrosis. However, both receptors of prostacyclin, prostacyclin receptor (IP) and peroxisome... 
ISCHEMIA-REPERFUSION INJURY | PPAR-ALPHA | PROSTAGLANDIN I-2 | MYOCARDIAL FIBROSIS | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | CREB-BINDING-PROTEIN | SMOOTH-MUSCLE-CELLS | NF-KAPPA-B | TYROSINE NITRATION | MOLECULAR PATHWAYS | Angiotensin II - pharmacology | Myocytes, Cardiac - cytology | Rats | DNA Primers | Rats, Sprague-Dawley | Epoprostenol - analogs & derivatives | Animals | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | Base Sequence | Myocytes, Cardiac - metabolism | Epoprostenol - pharmacology | Cell Proliferation - drug effects | Receptors, Epoprostenol - drug effects | Smad Proteins - metabolism | Transforming Growth Factor beta - metabolism | Heart | Neonates | Phosphorylation | Smad protein | Collagen (type I) | Immunoprecipitation | Transcription | Collagens | Smooth muscle | Prostacyclin | Nuclei | Proteins | CREB-binding protein | Receptors | Ischemia | Smad2 protein | Rodents | Fibroblasts | Inhibition | Angiotensin II | Heart diseases | Deoxyribonucleic acid--DNA | Analogue | Pulmonary arteries | Protein biosynthesis | Pharmacology | siRNA | Cyclic AMP response element-binding protein | Gene expression | Protein synthesis | Pharmacy | Collagen | Fibrosis | Angiotensin | Peroxisome proliferator-activated receptors | Receptor mechanisms | Laboratory animals | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article