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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2017, Volume 140, Issue 5, pp. 1364 - 1377.e2
Background Exposure to allergens, such as house dust mite (HDM), through the skin often precedes allergic inflammation in the lung. It was proposed that TH 2... 
Allergy and Immunology | airway inflammation | allergy | Epicutaneous sensitization | house dust mite | skin dendritic cells | CONTACT HYPERSENSITIVITY | CD4(+) T-CELLS | IMMUNOLOGY | LANGERHANS CELLS | ATOPIC-DERMATITIS | TIGHT JUNCTIONS | MEDIATED-IMMUNITY | INHALED ANTIGEN | IN-VIVO | TYPE-2 IMMUNITY | PROTEASE ACTIVITY | Dendritic Cells - immunology | Mice, Inbred C57BL | Cells, Cultured | Interferon Regulatory Factors - metabolism | Hypersensitivity - immunology | Mice, Transgenic | Th2 Cells - immunology | Arthropod Proteins - immunology | Antigens, Dermatophagoides - immunology | Animals | Antigen Presentation | Langerhans Cells - immunology | Mice | Receptors, Antigen, T-Cell - genetics | Cysteine Endopeptidases - immunology | Pyroglyphidae - immunology | Skin - immunology | Allergens | Enzymes | Dendritic cells | Genetic research | Genetic engineering | Skin | Interferon | Biological response modifiers | T cells | Genetic polymorphisms | Asthma | Cell proliferation | Mites | Lymphocytes T | Kinases | Adoptive transfer | Lymph nodes | Respiratory tract | T-cell receptor | Enzymatic activity | Lymphocytes | Transgenic animals | Nose | Respiratory tract diseases | Immune system | Antigen presentation | Lymphatic system | Leukocytes (eosinophilic) | Hypersensitivity | House dust | Inflammation | T cell receptors | Pattern recognition | Allergies | Drainage | Dust | Lungs | Antigen-presenting cells | Interferon regulatory factor 4 | Der p 1 antigen | Ear | Langerhans cells | Interferon regulatory factor | Life Sciences | Immunology
Journal Article
Journal Article
Clinical & Experimental Allergy, ISSN 0954-7894, 07/2017, Volume 47, Issue 7, pp. 946 - 960
Background: Allergy to the German cockroach (Blattella germanica) is a significant asthma risk factor for inner-city communities. Cockroach, like other... 
protease | asthma | proteinase‐activated receptor‐2 (PAR2) | calcium signalling | cockroach | proteinase-activated receptor-2 (PAR2) | DUST MITE ALLERGEN | PERIPLANETA-AMERICANA | DER-P-1 | IMMUNOLOGY | TANDEM MASS-SPECTROMETRY | IDENTIFICATION | CHILDREN | EPITHELIAL-CELLS | ALLERGY | INFLAMMATION | Amino Acid Sequence | Cell Line | Chromatography, Ion Exchange | Signal Transduction | Humans | Receptor, PAR-2 - metabolism | beta-Arrestins - metabolism | Hypersensitivity - immunology | Cockroaches - immunology | Animals | Allergens - immunology | Hypersensitivity - metabolism | Blattellidae - immunology | Hypersensitivity - genetics | Ligands | Serine Proteases - chemistry | Serine Proteases - immunology | Calcium Signaling | Receptor, PAR-2 - genetics | Allergens | Trypsin | Proteases | Serine | Enzyme kinetics | Cockroaches | Asthma | Phosphorylation | Enzyme activity | Calcium | Proteinase | Allergenicity | Risk factors | Expressed sequence tags | Calcium signalling | Respiratory tract | Receptors | Enzymatic activity | Proteolysis | Respiratory tract diseases | Libraries | Ion exchange | Enzymes | Hypersensitivity | Amino acid sequence | Extracellular signal-regulated kinase | MAP kinase | Ion exchanging | Inhibitors | Acids | Animal behavior | Ion-exchange chromatography | Skin | In vivo methods and tests | Serine proteinase | Kinetics | Skin tests | Proteinase-activated receptor-2 (PAR2) | calcium signaling
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, p. 6763
Asthma, a common disorder that affects 4250 million people worldwide, is defined by exaggerated bronchoconstriction to inflammatory mediators including... 
EXTRACELLULAR-MATRIX PROTEINS | ASPERGILLUS-FUMIGATUS | EPITHELIAL-CELLS | CONTRACTION | MULTIDISCIPLINARY SCIENCES | LUNG-DISEASE | SMOOTH-MUSCLE-CELLS | MECHANISMS | PEN C-13 | SERINE PROTEINASE | EXPRESSION | Histamine - biosynthesis | Calcium - metabolism | Humans | Immunoglobulin E - biosynthesis | Extracellular Matrix - immunology | Myocytes, Smooth Muscle - pathology | Calcium - immunology | Trachea - drug effects | Histamine - immunology | Bronchi - immunology | Extracellular Matrix - chemistry | Bronchi - drug effects | Allergens - administration & dosage | Allergens - immunology | Fungal Proteins - immunology | Bronchoconstriction - drug effects | Asthma - immunology | Bronchoconstriction - immunology | Female | Bacterial Proteins - immunology | rho GTP-Binding Proteins - immunology | Myocytes, Smooth Muscle - drug effects | Bronchi - pathology | Disease Models, Animal | Gene Expression | rho GTP-Binding Proteins - genetics | Extracellular Matrix - drug effects | Administration, Inhalation | Aspergillus fumigatus - chemistry | Bacterial Proteins - administration & dosage | Endopeptidases - administration & dosage | Endopeptidases - immunology | Trachea - immunology | Trachea - pathology | Animals | Aspergillus fumigatus - immunology | Myocytes, Smooth Muscle - immunology | Mice | Mice, Inbred BALB C | Primary Cell Culture | Asthma - pathology | Fungal Proteins - administration & dosage | Biodegradation | Allergens | Calcium | Serine | Medical treatment | Lung diseases | Muscles | Smooth muscle | RhoA protein | Inflammation | Asthma | Respiratory tract | Fungi | Histamine | Bronchoconstriction | Protease | Bradykinin | Extracellular matrix | Serine proteinase | Acetylcholine | Disruption | Calcium ions | Alkaline protease
Journal Article
Journal Article