Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (416) 416
life sciences & biomedicine (405) 405
proteasomal degradation (361) 361
humans (276) 276
biochemistry & molecular biology (173) 173
animals (172) 172
proteasome endopeptidase complex - metabolism (168) 168
cell biology (145) 145
ubiquitin (124) 124
ubiquitination (119) 119
proteins (95) 95
proteolysis (81) 81
mice (75) 75
ubiquitin - metabolism (61) 61
ubiquitin-protein ligases - metabolism (58) 58
phosphorylation (57) 57
oncology (54) 54
biophysics (53) 53
apoptosis (50) 50
cell line, tumor (50) 50
proteasomes (48) 48
protein binding (47) 47
cell line (46) 46
hek293 cells (46) 46
signal transduction (42) 42
gene expression (41) 41
analysis (40) 40
biology (40) 40
ligases (38) 38
research (38) 38
biological and medical sciences (37) 37
neurosciences (37) 37
mutation (36) 36
male (35) 35
neurosciences & neurology (35) 35
cancer (34) 34
genetic aspects (31) 31
cell cycle (30) 30
proteasome inhibitors (30) 30
autophagy (29) 29
enzymes (28) 28
genetics & heredity (28) 28
hela cells (28) 28
proteasome endopeptidase complex (28) 28
rats (28) 28
cells, cultured (27) 27
degradation (27) 27
nuclear proteins - metabolism (27) 27
ubiquitin-protein ligases - genetics (27) 27
female (26) 26
kinases (26) 26
life sciences (26) 26
physiological aspects (26) 26
proteasome (26) 26
leupeptins - pharmacology (25) 25
medical sciences (24) 24
proteasome endopeptidase complex - genetics (24) 24
tumors (24) 24
binding sites (23) 23
gene expression regulation (23) 23
protein stability (23) 23
review (23) 23
transfection (23) 23
amino acid sequence (22) 22
health aspects (22) 22
protein processing, post-translational (22) 22
blotting, western (21) 21
pharmacology & pharmacy (21) 21
viruses (21) 21
models, biological (20) 20
protein folding (20) 20
virology (20) 20
dna damage (19) 19
microbiology (19) 19
molecular biology (19) 19
parkinson's disease (19) 19
ubiquitin-proteasome system (19) 19
carrier proteins - metabolism (18) 18
molecular sequence data (18) 18
multienzyme complexes - metabolism (18) 18
nuclear proteins - genetics (18) 18
oxidative stress (18) 18
proteasomal activity (18) 18
research article (18) 18
transcription factors - metabolism (18) 18
biochemistry, general (17) 17
biomedicine (17) 17
cell nucleus - metabolism (17) 17
cysteine endopeptidases - metabolism (17) 17
development and progression (17) 17
dna-binding proteins - metabolism (17) 17
immunoprecipitation (17) 17
transcription factors (17) 17
cell death (16) 16
cell proliferation (16) 16
endoplasmic reticulum (16) 16
p53 (16) 16
proteases (16) 16
protein degradation (16) 16
time factors (16) 16
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (544) 544
French (5) 5
Japanese (4) 4
Korean (3) 3
German (2) 2
Russian (2) 2
Chinese (1) 1
Czech (1) 1
Polish (1) 1
Portuguese (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Small Molecule-Mediated TGF-β Type II Receptor Degradation Promotes Cardiomyogenesis in Embryonic Stem Cells
by Willems, Erik and Cabral-Teixeira, Joaquim and Schade, Dennis and Cai, Wenqing and Reeves, Patrick and Bushway, Paul J and Lanier, Marion and Walsh, Christopher and Kirchhausen, Tomas and Izpisua Belmonte, Juan Carlos and Cashman, John and Mercola, Mark
Cell stem cell, ISSN 1934-5909, 08/2012, Volume 11, Issue 2, pp. 242 - 252
Cell & Tissue Engineering | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Fundamental and applied biological sciences. Psychology | Cell receptors | Miscellaneous | Cell differentiation, maturation, development, hematopoiesis | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Cell structures and functions | Embryonic Stem Cells - metabolism | Protein-Serine-Threonine Kinases - deficiency | Embryonic Stem Cells - cytology | Molecular Weight | Membrane Glycoproteins - metabolism | Humans | Structure-Activity Relationship | Neoplasm Proteins - metabolism | Dose-Response Relationship, Drug | Proteolysis - drug effects | HEK293 Cells | Protein-Serine-Threonine Kinases - metabolism | Epidermal Growth Factor - deficiency | Dihydropyridines - chemistry | Myocytes, Cardiac - cytology | Cells, Cultured | Epidermal Growth Factor - metabolism | Down-Regulation - drug effects | Mice, Knockout | Animals | Myocytes, Cardiac - drug effects | Embryonic Stem Cells - drug effects | Receptors, Transforming Growth Factor beta - metabolism | Cell Differentiation - drug effects | Dihydropyridines - pharmacology | Myocytes, Cardiac - metabolism | Mice | Neoplasm Proteins - deficiency | Membrane Glycoproteins - deficiency | Receptors, Transforming Growth Factor beta - deficiency | Index Medicus | cardiogenesis | embryonic stem cells | TGFβ | Small molecule inhibitor | proteasomal degradation | mesoderm | 1,4-dihydropyridine
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Phosphorylation of WRINKLED1 by KIN10 Results in Its Proteasomal Degradation, Providing a Link between Energy Homeostasis and Lipid Biosynthesis
by Zhiyang Zhai and Hui Liu and John Shanklin and Brookhaven National Lab. (BNL), Upton, NY (United States)
The Plant cell, ISSN 1040-4651, 4/2017, Volume 29, Issue 4, pp. 871 - 889
RESEARCH ARTICLES | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Cell Biology | Arabidopsis Proteins - genetics | Phosphorylation | Plants, Genetically Modified - genetics | Tobacco - metabolism | Homeostasis | Transcription Factors - genetics | Arabidopsis - metabolism | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Transcription Factors - metabolism | Plant Proteins - genetics | Plants, Genetically Modified - metabolism | Tobacco - genetics | Gene Expression Regulation, Plant | Lipid Metabolism - genetics | Plant Proteins - metabolism | Energy Metabolism - genetics | Energy Metabolism - physiology | Lipid Metabolism - physiology | Genetic research | Biosynthesis | Research | Gene expression | Transcription factors | Sucrose | Nucleotide sequence | Lipids | Triglycerides | Kinases | Degradation | Energy balance | Signaling | E coli | Energy conservation | Proteasomes | Glycolysis | Sugar | Sugars | Deoxyribonucleic acid--DNA | Index Medicus | protein proteasomal degradation | TAG | fatty acids | BASIC BIOLOGICAL SCIENCES | Sugar sensing
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Synthesis of 7-benzylguanosine cap-analogue conjugates for eIF4E targeted degradation
by Kaur, Tanpreet and Menon, Arya and Garner, Amanda L
European journal of medicinal chemistry, ISSN 0223-5234, 03/2019, Volume 166, pp. 339 - 350
Proteasomal degradation | eIF4E | PROTACs | m7G cap | Cancer | G cap | Guanosine - analogs & derivatives | Chemistry Techniques, Synthetic | Humans | Eukaryotic Initiation Factor-4E - metabolism | Models, Molecular | Guanosine - chemical synthesis | Proteolysis - drug effects | Eukaryotic Initiation Factor-4E - chemistry | Guanosine - chemistry | Drug Design | Cell Line, Tumor | Guanosine - pharmacology | Protein Conformation | Proteolysis | Genetic translation | Therapeutics | Homeopathy | Materia medica and therapeutics | Index Medicus | cancer | proteasomal degradation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination
by Calabretta, Sara and Vogel, Gillian and Yu, Zhenbao and Choquet, Karine and Darbelli, Lama and Nicholson, Thomas B and Kleinman, Claudia L and Richard, Stéphane
Developmental cell, ISSN 1534-5807, 08/2018, Volume 46, Issue 4, pp. 426 - 440.e5
PRMT5 | PDGFRα | arginine methylation | ubiquitination | oligodendrocyte | myelination | receptor tyrosine kinase | cellular differentiation | Cbl | proteasomal degradation | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Disproportionately high levels of HGF induce the degradation of the c-met receptor through the proteasomal degradation pathway
by Lee, Nayeon and Lee, Junghun and Lee, Sang Hwan and Kim, Subin and Kim, Sunyoung
Biochemical and biophysical research communications, ISSN 0006-291X, 11/2018, Volume 505, Issue 3, pp. 925 - 930
Proteasomal degradation | RTK | Negative feedback | HGF | Migration | Y1003 | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Ubiquitin | Tyrosine | Metastasis | Endothelium | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Methyl-2-acetylamino-3-(4-hydroxyl-3,5-dimethoxybenzoylthio)propanoate suppresses melanogenesis through ERK signaling pathway mediated MITF proteasomal degradation
by Ha, Ji Hoon and Jeong, Yoon Ju and Xuan, Song Hua and Lee, Jae-Young and Park, Jino and Park, Soo Nam
Journal of dermatological science, ISSN 0923-1811, 08/2018, Volume 91, Issue 2, pp. 142 - 152
Microphthalmia-associated transcription factor | Proteasomal degradation | A reconstructed human skin tissue | ERK signaling pathway | Depigmentation | Life Sciences & Biomedicine | Dermatology | Science & Technology | Enzymes | Hydroxides | Analysis | Skin | Intermedin | Gene expression | Free radicals (Chemistry)
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Pseudorabies Virus Infection Accelerates Degradation of the Kinesin-3 Motor KIF1A
by Huang, Hao and Koyuncu, Orkide O and Enquist, Lynn W
Journal of virology, ISSN 0022-538X, 05/2020, Volume 94, Issue 9
Life Sciences & Biomedicine | Science & Technology | Virology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Ubiquitin‐Modulated Phase Separation of Shuttle Proteins: Does Condensate Formation Promote Protein Degradation?
by Dao, Thuy P and Castañeda, Carlos A
BioEssays, ISSN 0265-9247, 11/2020, Volume 42, Issue 11, pp. e2000036 - n/a
liquid‐liquid phase separation | autophagy | ubiquitin shuttle proteins | protein quality control | polyubiquitin | proteasomal degradation | biomolecular condensates | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Proteins | Ubiquitin | Degradation | Spacecraft components | Condensates | Liquid phases | Phase separation | Quality control | Proteasomes | Substrates | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation
by Lawlor, Kate E and Feltham, Rebecca and Yabal, Monica and Conos, Stephanie A and Chen, Kaiwen W and Ziehe, Stephanie and Graß, Carina and Zhan, Yifan and Nguyen, Tan A and Hall, Cathrine and Vince, Angelina J and Chatfield, Simon M and D’Silva, Damian B and Pang, Kenneth C and Schroder, Kate and Silke, John and Vaux, David L and Jost, Philipp J and Vince, James E
Cell reports (Cambridge), ISSN 2211-1247, 07/2017, Volume 20, Issue 3, pp. 668 - 682
caspase-8 | RIPK3 | autoinflammatory disease | TNFR2 | NLRP3 | XIAP | cIAP1 | interferon | Toll-like receptor | necroptosis | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Inhibitor of Apoptosis Proteins - genetics | TNF Receptor-Associated Factor 2 - genetics | Caspase 8 - metabolism | Myeloid Differentiation Factor 88 - genetics | TNF Receptor-Associated Factor 2 - metabolism | Interleukin-1beta - genetics | Mice, Knockout | Caspase 8 - genetics | Inhibitor of Apoptosis Proteins - deficiency | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Interleukin-1beta - metabolism | Proteolysis | Toll-Like Receptors - genetics | Cell Death | Inhibitor of Apoptosis Proteins - metabolism | Mice | Toll-Like Receptors - metabolism | Myeloid Differentiation Factor 88 - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights