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protecting groups (93) 93
chemistry, organic (85) 85
chemistry, multidisciplinary (45) 45
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solid-phase synthesis (32) 32
protecting group (31) 31
biochemistry & molecular biology (26) 26
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photochemie (7) 7
photoremovable protecting groups (7) 7
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cyclic-peptides (6) 6
efficient (6) 6
ethers (6) 6
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photolabile protecting groups (6) 6
polymers (6) 6
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Chemistry – A European Journal, ISSN 0947-6539, 01/2014, Volume 20, Issue 5, pp. 1258 - 1262
Three structurally related relay protecting groups for carboxylic acids that are based on chelating amines have been developed. These protecting groups can... 
amides | protecting groups | orthogonality | chelators | carboxylic acids | Chelators | Amides | Carboxylic acids | Orthogonality | Protecting groups | CHEMISTRY, MULTIDISCIPLINARY | Organic acids | Fluorides | Acids
Journal Article
Tetrahedron, ISSN 0040-4020, 2005, Volume 61, Issue 9, pp. 2493 - 2503
New deprotection conditions that provide a complete orthogonality between Tsc and Fmoc amino-protecting groups are described. The potential of these orthogonal... 
Orthogonal deprotection | Branched peptide | Fmoc | Tsc | Amino-protecting group | METHYLATION | ACID | SOLID-PHASE SYNTHESIS | ANALOGS | CHEMISTRY, ORGANIC | orthogonal deprotection | THIOESTERS | amino-protecting group | AQUEOUS-SOLUTION | REMOVAL | PEPTIDE-SYNTHESIS | branched peptide | POLYAMIDES | CYCLIZATION | Peptides
Journal Article
10/2009, Volume 2009, Issue 29, 10
For regioselective deprotection studies under SPOS conditions the glucosamine derivatives 4ab/4ba, 4ac/4ca and 4ad/4da – with Fmoc/PA, Fmoc/Lev or Fmoc/Alloc,... 
Carbohydrates | Glucosamine | Diols, vicinal | Oligosaccharides | Solid‐phase synthesis | Protecting groups | Solid-phase synthesis | COMPLEX | STRATEGY | CHEMISTRY, ORGANIC | HEXASACCHARIDE | LIBRARIES | SUPPORT | GLYCOSIDE-BOND FORMATION
Book Review
Tetrahedron Letters, ISSN 0040-4039, 08/2015, Volume 56, Issue 35, pp. 5010 - 5012
A monosaccharide unit was synthesized bearing four different temporary protecting groups. The protecting groups used (Fmoc carbonate, NAP ether, levulinoyl and... 
Monosaccharide Scaffold | Orthogonal protection | Protecting groups | Full orthogonality | LIBRARIES | DESIGN | BIOLOGICAL EVALUATION | CHEMISTRY, ORGANIC | OLIGOSACCHARIDE | Fructose
Journal Article
Carbohydrate letters, ISSN 1073-5070, 2000, Volume 4, Issue 1, pp. 21 - 27
The 1-phenyl-3-butenyl (PBU) protecting group was alternatively introduced in position 4 or 6 by regioselective opening of methyl... 
Carbohydrates | Regioselection | Protecting groups
Journal Article
Chemical Communications, ISSN 1359-7345, 1/2013, Volume 49, Issue 17, pp. 1679 - 1695
The concept of orthogonality has been applied to many areas of chemistry, ranging from wave functions to chromatography. But it was Barany and Merrifield's... 
TERPYRIDINE METAL-COMPLEXES | 1,3-DIPOLAR CYCLOADDITIONS | HYDROGEN-BONDED COMPLEXES | FREE TRIAZOLE FORMATION | ONE-POT SYNTHESIS | IN-VIVO | PROTECTING GROUPS | RAPID SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | DYNAMIC COMBINATORIAL LIBRARIES | THIOL-ENE CLICK | Binding | Self assembly | Peptides | Nanomaterials | Strategy | Activation | Nanostructure | Orthogonality
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 01/2016, Volume 22, Issue 4, pp. 1511 - 1521
Journal Article
Organic & Biomolecular Chemistry, ISSN 1477-0520, 01/2018, Volume 16, Issue 17, pp. 3114 - 3120
A new, simple protocol for the synthesis of acetals under basic conditions from non-enolizable aldehydes and alcohols has been reported. Such reactivity is... 
Synthesis | Sodium | Protecting groups | Alcohol | Aldehydes | Orthogonality | Acetals | Functional groups | Alcohols
Journal Article
Organic Letters, ISSN 1523-7060, 07/2007, Volume 9, Issue 14, pp. 2649 - 2651
The main challenge in developing new wavelength-specific photolabile protecting groups is the rigorous control of the photolysis rate. This rate is controlled... 
ORGANIC-SYNTHESIS | ETHERS | 2-NITROBENZYL COMPOUNDS | CHEMISTRY, ORGANIC | REACTION-MECHANISMS | ALDEHYDES | RELEASE | PHOTOREMOVABLE PROTECTING GROUPS | CLEAVAGE | DERIVATIVES
Journal Article
ACS Catalysis, ISSN 2155-5435, 10/2017, Volume 7, Issue 10, pp. 6821 - 6826
A highly efficient, catalytic strategy for the deprotection of classical phenacyl (Pac) as well as desyl (Dsy) protection groups has been developed using... 
Photoredox catalysis | Peptide synthesis | Acids | Orthogonality | Photocleavable linker | Protecting groups | ORGANIC-SYNTHESIS | P-HYDROXYPHENACYL | CHEMISTRY, PHYSICAL | RELEASE | orthogonality | protecting groups | acids | ROBUSTNESS SCREEN | ESTERS | SYNTHETIC APPLICATIONS | RAPID ASSESSMENT | photocleavable linker | photoredox catalysis | peptide synthesis | ECONOMY | CARBOXYLIC-ACIDS
Journal Article
Synlett, ISSN 0936-5214, 11/2004, Volume 2004, Issue 13, pp. 2268 - 2274
ABSTRACT A major challenge in organic synthesis is the selective reaction of a functional group in the presence of others. This can be achieved by using an... 
account | Cleavage | Chromophores | Protecting groups | Photochemistry | chromophores | protecting groups | cleavage | photochemistry | SOLID-PHASE SYNTHESIS | CHEMISTRY, ORGANIC | PHOTOLYSIS | LINKER | AMIDES
Journal Article
Pure and Applied Chemistry, ISSN 0033-4545, 02/2006, Volume 78, Issue 2, pp. 241 - 247
Journal Article
Tetrahedron, ISSN 0040-4020, 2009, Volume 65, Issue 22, pp. 4316 - 4325
Selective deprotection of aromatic ethers bearing two protecting groups on the same aromatic ring by solid-supported acids (Amberlyst-15 and PTS-Si) was... 
ALCOHOLS | MILD | SELECTIVE DEPROTECTION | ALLYL ETHERS | HYDROGENOLYSIS | CHEMISTRY, ORGANIC | PROTECTING GROUPS | NEUTRAL CONDITIONS | CATALYST | EFFICIENT | BENZYL ETHERS
Journal Article
Green Chemistry, ISSN 1463-9262, 2018, Volume 20, Issue 2, pp. 469 - 475
The present work shows that it is possible to ring-open cyclic carbonates with unprotected amino acids in water. Fine tuning of the reaction parameters made it... 
Naturvetenskap | Natural Sciences | Organisk kemi | Kemi | Chemical Sciences | Organic Chemistry
Journal Article
Pure and Applied Chemistry, ISSN 0033-4545, 01/2006, Volume 78, Issue 2, pp. 241 - 247
The photochemical liberation of functional groups is an attractive alternative to the traditional chemical approach. Several photolabile protecting groups have... 
photochemistry | protecting groups | chromatic orthogonality | ORGANIC-SYNTHESIS | ORTHOGONAL PHOTOLYSIS | ALDEHYDES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
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