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Journal Article
Nature Medicine, ISSN 1078-8956, 02/2004, Volume 10, Issue 2, pp. 168 - 174
Journal Article
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 01/2013, Volume 54, Issue 1, pp. 134 - 151
ETC-1002 (8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid) is a novel investigational drug being developed for the treatment of dyslipidemia and other... 
Fatty acid oxidation | LDL-cholesterol | Cardiovascular disease | Cholesterol synthesis | Metabolic syndrome | Fatty acid synthesis | RAT-LIVER | cardiovascular disease | cholesterol synthesis | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACETYL-COA CARBOXYLASE | RECEPTOR-ALPHA | metabolic syndrome | fatty acid synthesis | FATTY-ACID OXIDATION | INSULIN-RESISTANCE | DENSITY-LIPOPROTEIN | fatty acid oxidation | HEXADECANEDIOIC ACID | PEROXISOME PROLIFERATORS | HEPATOCYTE NUCLEAR FACTOR-4-ALPHA | ALPHA,OMEGA-DICARBOXYLIC ACIDS | Carbohydrate Metabolism - drug effects | AMP-Activated Protein Kinases - metabolism | ATP Citrate (pro-S)-Lyase - antagonists & inhibitors | Liver - enzymology | Fatty Acids - therapeutic use | Obesity - drug therapy | Calcium - metabolism | Diet - adverse effects | Humans | Male | Glucose - biosynthesis | Dicarboxylic Acids - pharmacology | Sterols - biosynthesis | Obesity - blood | Dicarboxylic Acids - therapeutic use | Dyslipidemias - blood | Liver - drug effects | Enzyme Inhibitors - chemistry | Female | Obesity - etiology | ATP Citrate (pro-S)-Lyase - metabolism | Molecular Targeted Therapy - methods | Protein-Serine-Threonine Kinases - metabolism | Biomarkers - metabolism | Cricetinae | Dyslipidemias - drug therapy | Fatty Acids - chemistry | Liver - metabolism | Enzyme Inhibitors - pharmacology | Rats | Biomarkers - blood | Enzyme Activation - drug effects | Enzyme Inhibitors - therapeutic use | Hep G2 Cells | Obesity - metabolism | Dicarboxylic Acids - chemistry | Animals | Signal Transduction - drug effects | Lipid Metabolism - drug effects | Dyslipidemias - metabolism | Glucagon - metabolism | Liver - cytology | Mice | Energy Metabolism - drug effects | Fatty Acids - biosynthesis | Fatty Acids - pharmacology
Journal Article
Journal Article
FASEB Journal, ISSN 0892-6638, 03/2009, Volume 23, Issue 3, pp. 709 - 719
Journal Article