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Neurology, ISSN 0028-3878, 06/2015, Volume 84, Issue 22, pp. 2247 - 2257
OBJECTIVE:To test blood and CSF neurofilament light chain (NfL) levels in relation to disease progression and survival in amyotrophic lateral sclerosis (ALS).... 
SURVIVAL | DIAGNOSIS | AXONAL DAMAGE | BRAIN-INJURY | DISEASE | CSF | ALS | MARKERS | CEREBROSPINAL-FLUID | PROTEINS | CLINICAL NEUROLOGY
Journal Article
Trends in Pharmacological Sciences, ISSN 0165-6147, 2015, Volume 36, Issue 5, pp. 297 - 309
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 07/2011, Volume 29, Issue 21, pp. 2866 - 2874
Purpose The results of the Iressa Pan-Asia Study (IPASS), which compared gefitinib and carboplatin/paclitaxel in previously untreated never-smokers and light... 
TRIAL | CHEMOTHERAPY-NAIVE PATIENTS | FACTOR-RECEPTOR GENE | PLACEBO | ONCOLOGY-GROUP | ONCOLOGY | TYROSINE KINASE | SENSITIVITY | EGFR MUTATIONS | MOLECULAR PREDICTORS | PREVIOUSLY TREATED PATIENTS | Immunohistochemistry | Lung Neoplasms - drug therapy | Predictive Value of Tests | Adenocarcinoma - pathology | Lung Neoplasms - mortality | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Time Factors | Gefitinib | Odds Ratio | Paclitaxel - administration & dosage | Adenocarcinoma - chemistry | Precision Medicine | ErbB Receptors - antagonists & inhibitors | Lung Neoplasms - chemistry | Risk Assessment | Risk Factors | Carboplatin - administration & dosage | In Situ Hybridization, Fluorescence | Logistic Models | Survival Rate | Adenocarcinoma - drug therapy | Biomarkers, Tumor - genetics | Mutation | Carcinoma, Non-Small-Cell Lung - chemistry | Adenocarcinoma of Lung | ErbB Receptors - genetics | Lung Neoplasms - pathology | Patient Selection | Female | Adenocarcinoma - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Biomarkers, Tumor - analysis | Carcinoma, Non-Small-Cell Lung - genetics | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Gene Dosage | Carcinoma, Non-Small-Cell Lung - mortality | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Asia | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | ErbB Receptors - analysis | Adenocarcinoma - mortality
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2012, Volume 367, Issue 9, pp. 795 - 804
Journal Article
Molecular Oncology, ISSN 1574-7891, 05/2015, Volume 9, Issue 5, pp. 960 - 966
A tumor biomarker is a molecular or process-based change that reflects the status of an underlying malignancy. A tumor biomarker may be identified and measured... 
Validation | Tumor biomarkers | Level of evidence | ONCOLOGY | CLINICAL ONCOLOGY/COLLEGE | RECOMMENDATIONS | AMERICAN SOCIETY | Biomarkers, Tumor - metabolism | Humans | Neoplasms - diagnosis | Care and treatment | Cancer | Tumors | Laboratories | Oncology | Biology | Malignancy | Metastasis | Patients | Investigations | Proteins | Validity | Precision medicine | Medical prognosis | Biomarkers | Differential diagnosis | Reviews | Review
Journal Article
Journal of Proteome Research, ISSN 1535-3893, 03/2012, Volume 11, Issue 3, pp. 1937 - 1948
Biomarkers are most frequently proteins that are measured in the blood. Their development largely relies on antibody creation to test the protein candidate... 
pancreatic cancer | chronic pancreatitis | multiple reaction monitoring (MRM) | selected reaction monitoring (SRM) | pancreas | targeted proteomics | biomarker | plasma | mass spectrometer | pancreatic ductal adenocarcinoma | DIAGNOSIS | BIOCHEMICAL RESEARCH METHODS | MARKERS | VALIDATION | RISK | ABUNDANCE | PEPTIDES | PROTEINS | Exoribonucleases | Area Under Curve | Chondroitin Sulfate Proteoglycans - chemistry | Humans | Keratan Sulfate - blood | Molecular Sequence Data | Case-Control Studies | Keratan Sulfate - chemistry | Peptide Mapping | Exonucleases - blood | Lumican | Tissue Inhibitor of Metalloproteinase-1 - chemistry | Tissue Inhibitor of Metalloproteinase-1 - blood | Amino Acid Sequence | Pancreatic Neoplasms - blood | Gelsolin - blood | Enzyme-Linked Immunosorbent Assay | Chondroitin Sulfate Proteoglycans - blood | Biomarkers, Tumor - blood | Carcinoma, Pancreatic Ductal - blood | Exonucleases - chemistry | Peptide Fragments - chemistry | Pilot Projects | 14-3-3 Proteins - blood | Proteomics | 14-3-3 Proteins - chemistry | ROC Curve | Biomarkers, Tumor - chemistry | Gelsolin - chemistry | Plasma | Selected reaction monitoring (SRM) | Biomarker | Targeted proteomics | Pancreatic ductal adenocarcinoma | Pancreatic cancer | Chronic pancreatitis | Multiple reaction monitoring (MRM) | Mass spectrometer | Pancreas
Journal Article
Journal Article
Aquatic Toxicology, ISSN 0166-445X, 06/2017, Volume 187, pp. 64 - 71
Journal Article
Science, ISSN 0036-8075, 10/2018, Volume 362, Issue 6411, pp. 197 - 197
Programmed cell death protein-1 (PD-1) and programmed cell death ligand-1 (PD-L1) checkpoint blockade immunotherapy elicits durable antitumor effects in... 
CELL LUNG-CANCER | MISMATCH-REPAIR DEFICIENCY | MUTATIONAL PROCESSES | METASTATIC MELANOMA | CTLA-4 BLOCKADE | MULTIDISCIPLINARY SCIENCES | COPY NUMBER | PROGRAMMED DEATH LIGAND-1 | SEQUENCING DATA | CLINICAL-RESPONSE | SOMATIC MUTATIONS | Antibodies, Monoclonal, Humanized - therapeutic use | Humans | Transcriptome | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Genetic Markers | Cell Cycle Checkpoints | Neoplasms - therapy | Neoplasms - genetics | Antineoplastic Agents, Immunological - therapeutic use | Immunotherapy | Inflammation - genetics | T-Lymphocytes - immunology | Tumor Burden - genetics | Biomarkers, Tumor - genetics | Mutation | Molecular Targeted Therapy - methods | Monoclonal antibodies | Genetic aspects | T cells | Biological markers | Gene expression | Cancer | Tumors | Apoptosis | Cell receptors | Physiological aspects | Diagnosis | Identification and classification | Methods | PD-1 protein | Clinical trials | Genomes | Biology | Lymphocytes T | Microsatellite instability | Data bases | Subgroups | Anticancer properties | Proteins | Cell activation | Pembrolizumab | Databases | Antigenicity | Lymphocytes | Deoxyribonucleic acid--DNA | Medical research | Stability | Microsatellites | Mortality | Melanoma | Data processing | Inflammation | Patients | Immune checkpoint | Cell death | Correlation analysis | PD-L1 protein | Biomarkers | Ligands | Antitumor activity | Cutoffs | Solid tumors
Journal Article