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Neuron, ISSN 0896-6273, 02/2013, Volume 77, Issue 3, pp. 425 - 439
Recent genome-wide association studies have linked common variants in the human genome to Parkinson@s disease (PD) risk. Here we show that the consequences of... 
LOCALIZATION | RETROMER | TRANSPORT | COMPLEX | KINASE | GENE-EXPRESSION | TRAFFICKING | ALPHA | NEURODEGENERATION | MICE | NEUROSCIENCES | rab5 GTP-Binding Proteins - genetics | Immunoprecipitation | Humans | Middle Aged | Cerebral Cortex - pathology | Male | Tubulin - genetics | rab GTP-Binding Proteins - genetics | Green Fluorescent Proteins - genetics | Statistics as Topic | Vesicle-Associated Membrane Protein 2 - genetics | Cerebral Cortex - cytology | Tyrosine 3-Monooxygenase | rab5 GTP-Binding Proteins - metabolism | Tubulin - metabolism | Transfection | Aged, 80 and over | Female | Neurons - metabolism | Parkinson Disease - metabolism | Protein-Serine-Threonine Kinases - metabolism | Animals, Newborn | Synaptosomal-Associated Protein 25 - genetics | rab GTP-Binding Proteins - metabolism | Genetic Predisposition to Disease | Genome-Wide Association Study | Parkinson Disease - pathology | Animals, Genetically Modified | Drosophila | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Rats | Parkinson Disease - genetics | Mutation - genetics | Rats, Sprague-Dawley | Protein Transport - genetics | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Animals | Polymorphism, Single Nucleotide - genetics | Aged | Mice | Synaptosomal-Associated Protein 25 - metabolism | Vesicle-Associated Membrane Protein 2 - metabolism | Parkinson's disease | Neurons | Genomics | Risk factors | Brain | Laboratories | Parkinsons disease | Kinases | Gene expression | Experiments | Defects | Proteins | Pathology | Insects | Neurodegeneration | Gene loci | Mutation | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2015, Volume 57, Issue 1, pp. 39 - 54
Journal Article
Nature Cell Biology, ISSN 1465-7392, 01/2010, Volume 12, Issue 1, pp. 19 - 30
Journal Article
Science, ISSN 0036-8075, 2/2008, Volume 319, Issue 5865, pp. 921 - 926
HIV-1 exploits multiple host proteins during infection. We performed a large-scale small interfering RNA screen to identify host factors required by HIV-1 and... 
T lymphocytes | HIV infections | HIV | Cell lines | Small interfering RNA | HeLa cells | Viruses | Infections | Genetic screening | Cells | Research Article | NUCLEAR IMPORT | COMPLEX | TRANSPORT | SNARE TLG1P | N-LINKED GLYCOSYLATION | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | GLYCOPROTEINS | CXCR4 | ENDOPLASMIC-RETICULUM | LATE GOLGI | HIV-1 - pathogenicity | Cytoskeletal Proteins - genetics | Human Immunodeficiency Virus Proteins - physiology | Genomics | Humans | rab GTP-Binding Proteins - genetics | Virus Internalization | Vesicular Transport Proteins - physiology | HIV-1 - physiology | RNA Interference | Transcription, Genetic | Cytoskeletal Proteins - physiology | Mediator Complex | Intracellular Signaling Peptides and Proteins - genetics | Proteins - physiology | HIV Infections - genetics | HIV Infections - virology | Vesicular Transport Proteins - genetics | Computational Biology | HIV-1 - genetics | Virus Integration | Karyopherins - physiology | Host-Pathogen Interactions | rab GTP-Binding Proteins - physiology | Virus Replication | Cell Line, Tumor | Karyopherins - genetics | RNA, Small Interfering | Intracellular Signaling Peptides and Proteins - physiology | HIV Infections - metabolism | Proteins | Gene targeting | RNA | Physiological aspects | Drug targeting | Genetic aspects | Research | Host-virus relationships | Properties | HIV infection | Health aspects | Biomedical research | Ribonucleic acid--RNA | Human immunodeficiency virus--HIV | Index Medicus
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 12/2008, Volume 19, Issue 12, pp. 5360 - 5372
Class III phosphatidylinositol 3-kinase (PI3-kinase) regulates multiple membrane trafficking. In yeast, two distinct PI3-kinase complexes are known: complex I... 
PRE-AUTOPHAGOSOMAL STRUCTURE | LATE ENDOSOMES | MOLECULAR MACHINERY | PROTEIN-KINASE | TRANS-GOLGI NETWORK | TUMOR-SUPPRESSOR | VPS34 PTDINS 3-KINASE | SACCHAROMYCES-CEREVISIAE | SELECTIVE AUTOPHAGY | SELF-DIGESTION | CELL BIOLOGY | Autophagy-Related Proteins | Adaptor Proteins, Vesicular Transport - classification | Humans | Adaptor Proteins, Vesicular Transport - genetics | Molecular Sequence Data | rab GTP-Binding Proteins - genetics | Autophagy - physiology | Phosphatidylinositol 3-Kinases - metabolism | Phylogeny | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Adaptor Proteins, Vesicular Transport - metabolism | Recombinant Fusion Proteins - metabolism | Multiprotein Complexes - metabolism | RNA Interference | Tumor Suppressor Proteins - genetics | Apoptosis Regulatory Proteins - genetics | Phagosomes - ultrastructure | Cell Membrane - metabolism | Membrane Proteins - metabolism | Androstadienes - metabolism | Beclin-1 | rab GTP-Binding Proteins - metabolism | Amino Acid Sequence | Cell Line | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Phagosomes - metabolism | Apoptosis Regulatory Proteins - metabolism | Endocytosis - physiology | Phosphatidylinositol 3-Kinases - genetics | Multiprotein Complexes - chemistry | Sequence Alignment | Animals | Recombinant Fusion Proteins - genetics | Signal Transduction - physiology | Mice | Index Medicus
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 4/2010, Volume 189, Issue 2, pp. 223 - 232
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2016, Volume 18, Issue 4, pp. 404 - 417
Journal Article