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Journal of Clinical Investigation, ISSN 0021-9738, 10/2011, Volume 121, Issue 10, pp. 4127 - 4137
Journal Article
Science Signaling, ISSN 1945-0877, 05/2012, Volume 5, Issue 225, pp. ra38 - ra38
Interferon-beta (IFN-beta) is widely used to treat multiple sclerosis (MS), and its efficacy was demonstrated in the setting of experimental autoimmune... 
RESPONSES | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | ACTIVATION | MULTIPLE-SCLEROSIS | DENDRITIC CELLS | MECHANISM | CASPASE-1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CENTRAL-NERVOUS-SYSTEM | EXPRESSION | NALP3 INFLAMMASOME | CELL BIOLOGY | Recombinant Proteins - therapeutic use | Proto-Oncogene Proteins c-vav - antagonists & inhibitors | Reactive Oxygen Species - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Encephalomyelitis, Autoimmune, Experimental - immunology | Suppressor of Cytokine Signaling 1 Protein | Male | Receptor, Interferon alpha-beta - physiology | Interleukin-1beta - genetics | Neuropeptides - physiology | Proto-Oncogene Proteins c-vav - physiology | Cytoskeletal Proteins - deficiency | Interferon-beta - therapeutic use | rac GTP-Binding Proteins - antagonists & inhibitors | Interleukin-1beta - biosynthesis | Caspase 1 - physiology | rac GTP-Binding Proteins - physiology | Disease Models, Animal | Carrier Proteins - physiology | Macrophages - physiology | Encephalomyelitis, Autoimmune, Experimental - physiopathology | Receptor, Interferon alpha-beta - deficiency | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Mice, Inbred C57BL | Mice, Transgenic | Mice, Knockout | Gene Expression Regulation - drug effects | Carrier Proteins - genetics | Inflammasomes - physiology | Animals | Apoptosis Regulatory Proteins | Interferon beta-1b | CD4-Positive T-Lymphocytes - transplantation | CARD Signaling Adaptor Proteins | Suppressor of Cytokine Signaling Proteins - antagonists & inhibitors | Suppressor of Cytokine Signaling Proteins - physiology | Mice | Enzyme Activation | rac1 GTP-Binding Protein | Neuropeptides - antagonists & inhibitors | Index Medicus
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2010, Volume 107, Issue 22, pp. 9944 - 9949
Actomyosin contractility affects cellular organization within tissues in part through the generation of mechanical forces at sites of cell—matrix and cell—cell... 
Cell growth | Microinjections | Epithelial cells | Bowties | Cell adhesion | Cadherins | Adherens junctions | Focal adhesions | Physiological regulation | Endothelial cells | Mechanotransduction | Traction force | Myosin | Adherens junction | PDMS | CONTACTS | ACTIVATION | mechanotransduction | MULTIDISCIPLINARY SCIENCES | MYOSIN IIB | myosin | EXTENSION | FOCAL ADHESIONS | traction force | SHAPE | adherens junction | RAC | GROWTH | RHO | VASCULAR ENDOTHELIAL-CADHERIN | Myosin Type II - physiology | rhoA GTP-Binding Protein - administration & dosage | Cadherins - metabolism | Mechanotransduction, Cellular - drug effects | Humans | Green Fluorescent Proteins - genetics | rhoA GTP-Binding Protein - physiology | rhoA GTP-Binding Protein - genetics | Mechanotransduction, Cellular - physiology | Antigens, CD - genetics | Antigens, CD - metabolism | Endothelial Cells - ultrastructure | Thrombin - pharmacology | Lysophospholipids - pharmacology | rac GTP-Binding Proteins - physiology | Cadherins - genetics | Endothelial Cells - physiology | Recombinant Proteins - metabolism | Green Fluorescent Proteins - metabolism | Cells, Cultured | Recombinant Proteins - genetics | rho GTP-Binding Proteins - physiology | Recombinant Proteins - administration & dosage | Sphingosine - pharmacology | Biomechanical Phenomena | Sphingosine - analogs & derivatives | Adherens Junctions - physiology | Adherens Junctions - drug effects | Adherens Junctions - ultrastructure | Amino Acid Substitution | Endothelial Cells - drug effects | Junctional complexes (Epithelium) | Cell junctions | Properties | Proteins | Biochemistry | Cells | Cell adhesion & migration | Index Medicus | Biological Sciences | Physical Sciences
Journal Article
Nature Cell Biology, ISSN 1465-7392, 02/2010, Volume 12, Issue 2, pp. 170 - 176
Journal Article
Cell, ISSN 0092-8674, 2010, Volume 140, Issue 4, pp. 579 - 589
Journal Article
Journal Article
Blood, ISSN 0006-4971, 05/2012, Volume 119, Issue 18, pp. 4253 - 4263
Journal Article
Journal Article
Nature Neuroscience, ISSN 1097-6256, 09/2004, Volume 7, Issue 9, pp. 923 - 929
The establishment of a polarized morphology is an essential step in the differentiation of neurons with a single axon and multiple dendrites. In cultured rat... 
NEURITOGENESIS | BREAKING | PROTEIN | RAC | GROWTH | AXON | RHO-GTPASES | ESTABLISHMENT | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | CELL POLARITY | Body Patterning - drug effects | Green Fluorescent Proteins | Embryo, Mammalian | Microtubule-Associated Proteins - metabolism | Neurons - cytology | rhoA GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - genetics | Cytochalasin D - pharmacology | RNA, Messenger - biosynthesis | Transfection - methods | Time Factors | Protein Kinase C - metabolism | Reverse Transcriptase Polymerase Chain Reaction - methods | Neurons - physiology | Neurons - drug effects | RNA Interference - physiology | Protein-Serine-Threonine Kinases - metabolism | Animals, Newborn | Proto-Oncogene Proteins - metabolism | Dendrites - drug effects | Dendrites - metabolism | Gene Transfer Techniques | GTP Phosphohydrolases - physiology | Cells, Cultured | Axons - drug effects | Axons - metabolism | Rats | rap GTP-Binding Proteins - physiology | cdc42 GTP-Binding Protein - physiology | Hippocampus - cytology | Body Patterning - physiology | Immunohistochemistry - methods | Proto-Oncogene Proteins c-akt | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Phalloidine - drug effects | Mice | Antibodies, Monoclonal - metabolism | Luminescent Proteins - metabolism | Physiological aspects | Research | Neurons | Guanosine triphosphatase | Polarity (Psychology) | Index Medicus
Journal Article