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Publication DateThe Journal of biological chemistry, ISSN 1083-351X, 2016, Volume 291, Issue 9, pp. 4323 - 4333
Receptors, Lysophosphatidic Acid - metabolism | Lysophospholipids - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | Extracellular Matrix - metabolism | Melanoma - enzymology | Podosomes - enzymology | Neoplasm Proteins - antagonists & inhibitors | Receptors, Lysophosphatidic Acid - agonists | Receptors, Lysophosphatidic Acid - genetics | cdc42 GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - genetics | Endothelins - metabolism | Neoplasm Proteins - metabolism | Time-Lapse Imaging | Podosomes - metabolism | RNA Interference | cdc42 GTP-Binding Protein - antagonists & inhibitors | Fluorescence Resonance Energy Transfer | Receptors, Lysophosphatidic Acid - antagonists & inhibitors | Neoplasm Proteins - genetics | Biomarkers - metabolism | Melanoma - metabolism | Recombinant Proteins - metabolism | rac1 GTP-Binding Protein - agonists | rhoA GTP-Binding Protein - antagonists & inhibitors | Recombinant Proteins - genetics | Melanoma - pathology | cdc42 GTP-Binding Protein - agonists | Hydrolysis | Podosomes - pathology | Microscopy, Confocal | Neoplasm Proteins - agonists | cdc42 GTP-Binding Protein - genetics | Receptors, G-Protein-Coupled - antagonists & inhibitors | rac1 GTP-Binding Protein - antagonists & inhibitors | Cell Line, Tumor | Luminescent Proteins - genetics | Receptors, G-Protein-Coupled - genetics | Extracellular Matrix - pathology | Microscopy, Fluorescence | rac1 GTP-Binding Protein - metabolism | Luminescent Proteins - metabolism | rac1 GTP-Binding Protein - genetics | Index Medicus | CDC42 | invadopodia | biosensor | fluorescence resonance energy transfer (FRET) | calcium intracellular release | G protein-coupled receptor (GPCR) | Rho (Rho GTPase) | phosphatidylinositide 3-kinase (PI 3-kinase) | imaging | Rac (Rac GTPase) | Cell Biology
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Loading RightsThe Journal of cell biology, ISSN 0021-9525, 04/2012, Volume 197, Issue 3, pp. 439 - 455
Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Phosphatidylinositol Phosphates - metabolism | Humans | Extracellular Matrix - metabolism | cdc42 GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - genetics | Cell Movement - physiology | Myosin Type II - metabolism | rho-Associated Kinases - metabolism | cdc42 GTP-Binding Protein - antagonists & inhibitors | Microscopy, Atomic Force | Cell Culture Techniques | Dermis - cytology | Fibroblasts - metabolism | Dermis - metabolism | Cells, Cultured | Cell Communication | rhoA GTP-Binding Protein - antagonists & inhibitors | Blotting, Western | Animals | cdc42 GTP-Binding Protein - genetics | Fluorescent Antibody Technique | rac1 GTP-Binding Protein - antagonists & inhibitors | Fibroblasts - cytology | Mice | Pseudopodia - physiology | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Fibroblasts | Physiological aspects | Inositol | Research | Health aspects | Cell migration | Proteins | Matrix | Three dimensional imaging | Kinases | Cell adhesion & migration | Index Medicus
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Loading RightsCell death & disease, ISSN 2041-4889, 01/2014, Volume 5, Issue 11, pp. e1517 - e1517
Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Leucine - pharmacology | Mesothelioma - pathology | Apoptosis - drug effects | Farnesol - pharmacology | Humans | Gene Expression Regulation, Neoplastic | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | cdc42 GTP-Binding Protein - metabolism | rab GTP-Binding Proteins - genetics | rhoA GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - genetics | Protein Prenylation | Transferases - genetics | cdc42 GTP-Binding Protein - antagonists & inhibitors | Transferases - metabolism | Leucine - analogs & derivatives | Diterpenes - pharmacology | rab GTP-Binding Proteins - metabolism | DNA Topoisomerases, Type II - metabolism | Myeloid Cell Leukemia Sequence 1 Protein - antagonists & inhibitors | Signal Transduction | rhoA GTP-Binding Protein - antagonists & inhibitors | Imidazoles - pharmacology | Mesothelioma - genetics | S Phase - genetics | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Diphosphonates - antagonists & inhibitors | Mesothelioma - metabolism | cdc42 GTP-Binding Protein - genetics | rac1 GTP-Binding Protein - antagonists & inhibitors | Cell Line, Tumor | DNA Topoisomerases, Type II - genetics | rab GTP-Binding Proteins - antagonists & inhibitors | Imidazoles - antagonists & inhibitors | S Phase - drug effects | Diphosphonates - pharmacology | rac1 GTP-Binding Protein - metabolism | RNA, Small Interfering - metabolism | rac1 GTP-Binding Protein - genetics | Index Medicus | Original
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Loading RightsThe Journal of biological chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 40, pp. 15397 - 15418
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Proto-Oncogene Proteins c-met - metabolism | RNA, Small Interfering - genetics | Epithelial Cells - metabolism | Cytoskeletal Proteins - antagonists & inhibitors | Cytoskeletal Proteins - genetics | Neuroglia - pathology | Epithelial Cells - drug effects | Humans | Gene Expression Regulation, Neoplastic | rac GTP-Binding Proteins - metabolism | Protein Transport - drug effects | Hepatocyte Growth Factor - pharmacology | Neuroglia - drug effects | Cell Membrane - chemistry | rac GTP-Binding Proteins - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | rac GTP-Binding Proteins - genetics | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Cytoskeletal Proteins - metabolism | Cell Membrane - metabolism | Cell Membrane - drug effects | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Signal Transduction | Neoplasm Invasiveness | Proto-Oncogene Proteins c-met - antagonists & inhibitors | rac1 GTP-Binding Protein - agonists | Epithelial Cells - pathology | Proto-Oncogene Proteins - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Proto-Oncogene Proteins c-met - genetics | Cell Movement - drug effects | Receptor Protein-Tyrosine Kinases - genetics | Adaptor Proteins, Signal Transducing - genetics | rac1 GTP-Binding Protein - antagonists & inhibitors | Cell Line, Tumor | Neuroglia - metabolism | Cell Proliferation - drug effects | Adaptor Proteins, Signal Transducing - metabolism | rac1 GTP-Binding Protein - metabolism | RNA, Small Interfering - metabolism | rac1 GTP-Binding Protein - genetics | Index Medicus | glioblastoma | Ras-related C3 botulinum toxin substrate 1 (Rac1) | cell signaling | cell migration | receptor tyrosine kinase | cancer | cell invasion | guanine nucleotide exchange factor (GEF)
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Loading RightsNature (London), ISSN 0028-0836, 09/2009, Volume 461, Issue 7260, pp. 104 - 108
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Motility and taxis | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Flavoproteins - chemistry | rho GTP-Binding Proteins - antagonists & inhibitors | Cell Surface Extensions | Fluorescence Recovery After Photobleaching | Humans | Crystallography, X-Ray | rac1 GTP-Binding Protein - radiation effects | Avena - genetics | Fibroblasts | Myosins - metabolism | rac1 GTP-Binding Protein - chemistry | Genetic Engineering - methods | Cell Line | Flavoproteins - metabolism | Cell Survival | Flavoproteins - genetics | Crystallization | Models, Molecular | Enzyme Activation - radiation effects | Cell Movement - radiation effects | Animals | Embryo, Mammalian - cytology | rho GTP-Binding Proteins - metabolism | Cryptochromes | Protein Conformation | Mice | HeLa Cells | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Measurement | Control | Motility | Physiological aspects | Research | Cells | Proteins | Studies | Hydrogen bonds | Motion pictures | Mutation | Binding sites | Crystal structure | Index Medicus
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Loading RightsCellular signalling, ISSN 0898-6568, 05/2013, Volume 25, Issue 5, pp. 1075 - 1085
Dvl2 | Breast cancer | Rac1 | Rab35 | Wnt5a | Migration | Immunoprecipitation | Humans | rab GTP-Binding Proteins - genetics | rhoA GTP-Binding Protein - metabolism | Phosphoproteins - antagonists & inhibitors | Wnt-5a Protein | Breast Neoplasms | Phosphoproteins - metabolism | Wnt Proteins - metabolism | Wnt Proteins - genetics | MCF-7 Cells | RNA Interference | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Female | Dishevelled Proteins | Proto-Oncogene Proteins - metabolism | rab GTP-Binding Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Signal Transduction | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | Adaptor Proteins, Signal Transducing - genetics | rac1 GTP-Binding Protein - antagonists & inhibitors | rab GTP-Binding Proteins - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - metabolism | Wnt Proteins - antagonists & inhibitors | rac1 GTP-Binding Protein - metabolism | Cell Movement | RNA, Small Interfering - metabolism | rac1 GTP-Binding Protein - genetics | Development and progression | G proteins | Cancer cells | Index Medicus | Cellular | Ribonucleic acids | Breast | Activation | Gene expression | Signalling | Cancer | Biological
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Loading RightsThe FASEB journal, ISSN 0892-6638, 09/2014, Volume 28, Issue 9, pp. 4077 - 4087
spaceflight | VEGF | MG‐63 | RhoA | Cdc42 | Spaceflight | MG-63 | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Humans | Actins - metabolism | cdc42 GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - metabolism | Vascular Endothelial Growth Factor A - metabolism | rhoA GTP-Binding Protein - genetics | Vascular Endothelial Growth Factor A - genetics | Microtubules - metabolism | cdc42 GTP-Binding Protein - antagonists & inhibitors | Osteoblasts - cytology | Real-Time Polymerase Chain Reaction | Gravity Sensing | Signal Transduction | RNA, Messenger - genetics | Cell Physiological Phenomena | Cells, Cultured | rhoA GTP-Binding Protein - antagonists & inhibitors | Weightlessness | Reverse Transcriptase Polymerase Chain Reaction | Space Flight | Mechanotransduction, Cellular | cdc42 GTP-Binding Protein - genetics | rac1 GTP-Binding Protein - antagonists & inhibitors | Cytoskeleton - metabolism | Osteoblasts - metabolism | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Index Medicus | Research Communications
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Loading RightsChemMedChem, ISSN 1860-7179, 04/2018, Volume 13, Issue 7, pp. 754 - 761
inhibitors | CNF1 | screening | Rac1 | drug discovery | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Human Umbilical Vein Endothelial Cells | Immunoassay | Small Molecule Libraries - pharmacology | Humans | Monensin - pharmacology | Escherichia coli Proteins - metabolism | Drug Repositioning | Escherichia coli - chemistry | Lasalocid - pharmacology | Bacterial Toxins - adverse effects | Escherichia coli Proteins - adverse effects | Bacterial Toxins - antagonists & inhibitors | rac1 GTP-Binding Protein - immunology | Amodiaquine - pharmacology | Bacterial Toxins - metabolism | Diphtheria Toxin - adverse effects | Escherichia coli Proteins - antagonists & inhibitors | HeLa Cells | rac1 GTP-Binding Protein - chemistry | rac1 GTP-Binding Protein - metabolism | Bepridil - pharmacology | Drugs | Bacterial infections | Drug discovery | Drug approval | Gastrointestinal diseases | Escherichia coli | Biodegradation | Lasalocid | Monensin | Cytotoxic necrotizing factor | Fluorescence | Cytotoxicity | Rac1 protein | Inflammation | Infections | Diphtheria | Degradation | Inhibitors | E coli | Intestine | Cytotoxic necrotizing factor 1 | Proteasomes | Necrotizing factor 1 | Amodiaquine | Intoxication | Diphtheria toxin | Index Medicus | Bacterial Toxins/adverse effects | rac1 GTP-Binding Protein/immunology | Diphtheria Toxin/adverse effects | Lasalocid/pharmacology | Cellular Biology | Bacterial Toxins/antagonists & inhibitors | Life Sciences | Bepridil/pharmacology | Monensin/pharmacology | Small Molecule Libraries/pharmacology | Bacterial Toxins/metabolism | Subcellular Processes | rac1 GTP-Binding Protein/chemistry | Cell Behavior | Amodiaquine/pharmacology | Escherichia coli Proteins/antagonists & inhibitors | Bacteriology | Microbiology and Parasitology | Escherichia coli Proteins/adverse effects | Escherichia coli Proteins/metabolism | Escherichia coli/chemistry | rac1 GTP-Binding Protein/metabolism
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Loading RightsCellular signalling, ISSN 0898-6568, 01/2018, Volume 42, pp. 88 - 96
Chemokine receptor | Antagonist | Rac1 | Chemotaxis | Ligand bias | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Humans | Receptors, CCR5 - genetics | cdc42 GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - genetics | Pyrones - pharmacology | Quinolines - pharmacology | DNA-Binding Proteins - metabolism | Receptors, CCR5 - metabolism | Peptides - chemical synthesis | MCF-7 Cells | Receptors, CXCR4 - genetics | Aminoquinolines - pharmacology | Amino Acid Sequence | DNA-Binding Proteins - antagonists & inhibitors | Signal Transduction | Jurkat Cells | Gene Expression Regulation | THP-1 Cells | Chemokine CCL3 - pharmacology | Transcription Factors - antagonists & inhibitors | Chemotaxis - drug effects | Cytoskeleton - ultrastructure | Pyrimidines - pharmacology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Peptides - pharmacology | Receptors, CXCR4 - metabolism | Transcription Factors - metabolism | Receptors, CCR1 - genetics | Chemokine CXCL12 - pharmacology | cdc42 GTP-Binding Protein - genetics | Receptors, CCR1 - metabolism | rac1 GTP-Binding Protein - antagonists & inhibitors | Cytoskeleton - metabolism | Cytoskeleton - drug effects | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Phosphates | G proteins | T cells | Muscle proteins | Membrane proteins | Index Medicus
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Loading RightsExperimental cell research, ISSN 0014-4827, 07/2007, Volume 313, Issue 11, pp. 2504 - 2520
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Proto-Oncogene Proteins c-vav - antagonists & inhibitors | Proto-Oncogene Proteins c-vav - genetics | Humans | rac GTP-Binding Proteins - metabolism | Male | Lung - cytology | Respiratory Distress Syndrome, Adult - metabolism | Adherens Junctions - metabolism | rac GTP-Binding Proteins - antagonists & inhibitors | Blood-Air Barrier - drug effects | Cyclic AMP-Dependent Protein Kinases - genetics | Guanine Nucleotide Exchange Factors - metabolism | rac GTP-Binding Proteins - genetics | Epoprostenol - pharmacology | Lung - metabolism | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Cyclic AMP - metabolism | T-Lymphoma Invasion and Metastasis-inducing Protein 1 | Cyclic AMP-Dependent Protein Kinases - metabolism | Dinoprostone - pharmacology | Guanine Nucleotide Exchange Factors - genetics | Cytoskeleton - pathology | Respiratory Distress Syndrome, Adult - prevention & control | Endothelial Cells - metabolism | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Cells, Cultured | Blood-Air Barrier - cytology | Permeability | Adherens Junctions - pathology | Epoprostenol - analogs & derivatives | Animals | Blood-Air Barrier - metabolism | Guanine Nucleotide Exchange Factors - antagonists & inhibitors | Lung - drug effects | Adherens Junctions - drug effects | rac1 GTP-Binding Protein - antagonists & inhibitors | Cytoskeleton - metabolism | Mice | Cytoskeleton - drug effects | Proto-Oncogene Proteins c-vav - metabolism | rac1 GTP-Binding Protein - metabolism | Endothelial Cells - drug effects | rac1 GTP-Binding Protein - genetics | Index Medicus
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