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Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2012, Volume 287, Issue 7, pp. 5059 - 5069
Compromised clearance of all-trans-retinal (atRAL), a component of the retinoid cycle, increases the susceptibility of mouse retina to acute light-induced... 
VISUAL CYCLE | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | 5-HT1A RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHOLIPASE-C | IN-VIVO | RECESSIVE RETINITIS-PIGMENTOSA | GENE ABCR | BINDING-PROPERTIES | NEUTROPHIL NADPH-OXIDASE | Reactive Oxygen Species - metabolism | Receptor, Serotonin, 5-HT2A - genetics | Calcium - metabolism | Humans | NADPH Oxidases - metabolism | Corneal Dystrophies, Hereditary - genetics | Type C Phospholipases - metabolism | Retinaldehyde - metabolism | Alcohol Oxidoreductases - genetics | ATP-Binding Cassette Transporters - genetics | Corneal Dystrophies, Hereditary - pathology | ATP-Binding Cassette Transporters - metabolism | NADPH Oxidases - genetics | Signal Transduction | Light - adverse effects | Receptor, Muscarinic M3 - metabolism | Alcohol Oxidoreductases - metabolism | Corneal Dystrophies, Hereditary - metabolism | Receptor, Muscarinic M3 - genetics | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Mice, Knockout | Macular Degeneration - metabolism | Animals | Macular Degeneration - genetics | Type C Phospholipases - genetics | Mice | Inositol 1,4,5-Trisphosphate - genetics | Photoreceptor Cells, Vertebrate - metabolism | Receptor, Serotonin, 5-HT2A - metabolism | Inositol 1,4,5-Trisphosphate - metabolism | Photoreceptor Cells, Vertebrate - pathology | Macular Degeneration - pathology | Index Medicus | Molecular Bases of Disease | Vitamin A | Retinal metabolism | Vision | Reactive oxygen species (ROS) | Retinoid
Journal Article
Gene Therapy, ISSN 0969-7128, 10/2008, Volume 15, Issue 19, pp. 1311 - 1320
Journal Article
American Journal of Ophthalmology, ISSN 0002-9394, 11/2018, Volume 195, pp. 16 - 25
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2017, Volume 114, Issue 15, pp. 3987 - 3992
Recessive Stargardt macular degeneration (STGD1) is caused by mutations in the gene for the ABCA4 transporter in photoreceptor outer segments. STGD1 patients... 
Recessive Stargardt macular degeneration | Bisretinoids | Complement system | Gene therapy | Retinal pigment epithelium | VISUAL CYCLE | CELLS | ACTIVATION | complement system | MULTIDISCIPLINARY SCIENCES | recessive Stargardt macular degeneration | gene therapy | MACULAR DEGENERATION | CHOROIDAL NEOVASCULARIZATION | RECEPTOR-OPSIN | RPE LIPOFUSCIN | MEMBRANE-ATTACK-COMPLEX | REGULATORY PROTEINS | retinal pigment epithelium | bisretinoids | GEOGRAPHIC ATROPHY | Dependovirus - genetics | Retinal Pigment Epithelium - metabolism | Retinoids - metabolism | Oxidative Stress | Complement C3 - metabolism | Gene Expression Regulation | Autophagy | Receptors, Complement - metabolism | Macular Degeneration - metabolism | Retinal Pigment Epithelium - pathology | Animals | Macular Degeneration - congenital | ATP-Binding Cassette Transporters - genetics | Mice, Mutant Strains | Receptors, Complement - genetics | Mice, Inbred BALB C | Photoreceptor Cells, Vertebrate - metabolism | Lipofuscin - metabolism | Photoreceptor Cells, Vertebrate - pathology | Injections, Intraocular | Disease Models, Animal | Macular Degeneration - pathology | Oxidative stress | Complement receptors | Complement component C3b | Retina | Viruses | Activation | Complement | Accumulation | Proteins | Macular degeneration | Genotype & phenotype | Etiology | Coding | Rodents | Modulation | Pigments | Degeneration | Recombinant | Crry protein | Therapeutic applications | Visual observation | Complement regulatory proteins | Gene expression | Epithelium | Complement activation | Complement component C3 | Retinal degeneration | Photoreceptors | Mice | Mutation | Transporter | Index Medicus | Biological Sciences
Journal Article