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life sciences & biomedicine (10) 10
science & technology (10) 10
spd1 (8) 8
humans (4) 4
cell cycle proteins - metabolism (3) 3
fission yeast (3) 3
immunology (3) 3
ribonucleotide reductase (3) 3
amino acid sequence (2) 2
biochemistry & molecular biology (2) 2
blotting, western (2) 2
cell biology (2) 2
cell cycle proteins - genetics (2) 2
cell proliferation (2) 2
ddb1 (2) 2
flow cytometry (2) 2
genetics (2) 2
infectious diseases (2) 2
internal medicine (2) 2
medical colleges (2) 2
microbiology (2) 2
molecular sequence data (2) 2
mutation (2) 2
protein binding (2) 2
proteins (2) 2
research article (2) 2
schizosaccharomyces - metabolism (2) 2
schizosaccharomyces pombe proteins - metabolism (2) 2
sequence homology, amino acid (2) 2
spd1 protein (2) 2
t cells (2) 2
tumors (2) 2
whole genome sequencing (2) 2
activator for thyroid hormone and retinoid receptors (1) 1
akt protein (1) 1
alanine (1) 1
analysis (1) 1
animal models (1) 1
animals (1) 1
antigens (1) 1
apoptosis (1) 1
bacterial proteins - genetics (1) 1
bacteriology (1) 1
bcl-x protein (1) 1
biological and medical sciences (1) 1
calreticulin - administration & dosage (1) 1
calreticulin - immunology (1) 1
cancer (1) 1
cancer research (1) 1
cation transport proteins - chemistry (1) 1
cation transport proteins - genetics (1) 1
cd3 antigen (1) 1
cdc2 protein (1) 1
cdc2 protein kinase - metabolism (1) 1
cdc22 (1) 1
cdc2p (1) 1
cds1 gene (1) 1
cds1 protein (1) 1
cdt2 (1) 1
cell cycle proteins - chemistry (1) 1
cell death (1) 1
cell line, tumor (1) 1
cell separation (1) 1
cells, cultured (1) 1
checkpoint kinase (1) 1
child (1) 1
chimeric antigen receptor (1) 1
chimeric antigen receptors (1) 1
china (1) 1
chk1 protein (1) 1
circular dichroism (1) 1
cloning, molecular (1) 1
copia (1) 1
crl4 (1) 1
crt (1) 1
cul4 (1) 1
cycadopsida - classification (1) 1
cycadopsida - genetics (1) 1
ddb1 gene (1) 1
ddb1-cul4 (1) 1
ddb1–cul4cdt2 ubiquitin ligase (1) 1
degron (1) 1
deoxyribonucleases - classification (1) 1
deoxyribonucleases - genetics (1) 1
deoxyribonucleic acid--dna (1) 1
deoxyribonucleotides - metabolism (1) 1
dermatology (1) 1
development and progression (1) 1
disease (1) 1
disease outbreaks (1) 1
dna - chemistry (1) 1
dna damage (1) 1
dna repair (1) 1
dna replication (1) 1
dna replication - physiology (1) 1
dna replication checkpoint (1) 1
dna sequencing (1) 1
dna, plant - analysis (1) 1
dna-binding proteins - genetics (1) 1
dna-binding proteins - metabolism (1) 1
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1. Full Text Temperature‐dependent structural changes in intrinsically disordered proteins: Formation of α‒helices or loss of polyproline II?
by Kjaergaard, Magnus and Nørholm, Ann‒Beth and Hendus‒Altenburger, Ruth and Pedersen, Stine F and Poulsen, Flemming M and Kragelund, Birthe B
Protein science, ISSN 0961-8368, 08/2010, Volume 19, Issue 8, pp. 1555 - 1564
transient secondary structure | polyproline II | S‒phase delayed 1 (Spd1) | activator for thyroid hormone and retinoid receptors (ACTR) | temperature dependence | circular dichroism (CD) | intrinsically disordered protein (IDP) | sodium–proton (Na+/H+) exchanger 1 (NHE1) | nuclear magnetic resonance spectroscopy (NMR) | Sodium-proton (Na+/H+) exchanger 1 (NHE1) | Temperature dependence | Transient secondary structure | Intrinsically disordered protein (IDP) | Nuclear magnetic resonance spectroscopy (NMR) | Circular dichroism (CD) | Polyproline II | Activator for thyroid hormone and retinoid receptors (ACTR) | S-phase delayed 1 (Spd1) | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Fungal Proteins - chemistry | Temperature | Peptides - chemistry | Protein Structure, Secondary | Humans | Scattering, Small Angle | Fungal Proteins - genetics | Sodium-Hydrogen Exchangers - chemistry | Nuclear Magnetic Resonance, Biomolecular | Cation Transport Proteins - genetics | Sodium-Hydrogen Exchangers - genetics | Cation Transport Proteins - chemistry | Circular Dichroism | Sodium-Hydrogen Exchanger 1 | Index Medicus | sodium–proton (Na+ | H+) exchanger 1 (NHE1
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2. Full Text Serum levels of soluble PD1 in pemphigus vulgaris: A useful marker for disease severity
by Zeid, Ola Abu and Rashed, Laila and Khalifa, Shimaa and Saleh, Marwah Adly and Ragab, Nanis
Journal of cosmetic dermatology, ISSN 1473-2130, 2020
PDAI | Pemphigus vulgaris | PD1 | sPD1 | Life Sciences & Biomedicine | Dermatology | Science & Technology | Index Medicus
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3. Full Text Break-induced ATR and Ddb1-Cul4Cdt2 ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast
by Moss, Jennifer and Tinline-Purvis, Helen and Walker, Carol A and Folkes, Lisa K and Stratford, Michael R and Hayles, Jacqueline and Hoe, Kwang-Lae and Kim, Dong-Uk and Park, Han-Oh and Kearsey, Stephen E and Fleck, Oliver and Holmberg, Christian and Nielsen, Olaf and Humphrey, Timothy C
Genes & development, ISSN 0890-9369, 12/2010, Volume 24, Issue 23, pp. 2705 - 2716
ubiquitin ligase | Homologous recombination repair | Ribonucleotide reductase | Fission yeast | Ddb1-Cul4 | Rad3 | Spd1 | ribonucleotide reductase | Ddb1–Cul4Cdt2 ubiquitin ligase | homologous recombination repair | Research Paper | fission yeast
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4. Full Text Increased antitumor activities of glypican-3-specific chimeric antigen receptor-modified T cells by coexpression of a soluble PD1–CH3 fusion protein
by Pan, Zeyan and Di, Shengmeng and Shi, Bizhi and Jiang, Hua and Shi, Zhimin and Liu, Ying and Wang, Yi and Luo, Hong and Yu, Min and Wu, Xiuqi and Li, Zonghai
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 10/2018, Volume 67, Issue 10, pp. 1621 - 1634
Immunology | Medicine & Public Health | Chimeric antigen receptor | PD-1/PD-L1 | Oncology | Cancer Research | Hepatocellular carcinoma | Glypican-3 | sPD1 | Life Sciences & Biomedicine | Science & Technology | Antigens | Medical colleges | T cells | Cell death | Immunoglobulin G | Cell proliferation | Animal models | PD-1 protein | AKT protein | Lymphocytes T | CD3 antigen | Proteins | Chimeric antigen receptors | Granzyme B | Bcl-x protein | Lymphocytes | PD-L1 protein | Xenografts | Heparan sulfate proteoglycans | Solid tumors | Fusion protein | Apoptosis | Tumors | Index Medicus
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5. Full Text A heterozygous duplication variant of the HOXD13 gene caused synpolydactyly type 1 with variable expressivity in a Chinese family
by Zaib, Tahir and Ji, Wei and Saleem, Komal and Nie, Guangchen and Li, Chao and Cao, Lin and Xu, Baijun and Dong, Kexian and Yu, Hanfei and Hao, Xuguang and Xue, Yan and Si, Shuhan and Jia, Xueyuan and Wu, Jie and Zhang, Xuelong and Guan, Rongwei and Ji, Guohua and Bai, Jing and Chen, Feng and Liu, Yong and Sun, Wenjing and Fu, Songbin
BMC medical genetics, ISSN 1471-2350, 12/2019, Volume 20, Issue 1, pp. 203 - 203
Variable expressivity | HOXD13 | SPD1 | Whole genome sequencing | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Gene Duplication | Exons | Humans | Male | Transcription Factors - genetics | Homeodomain Proteins - genetics | Pedigree | China | Female | Heterozygote | Mutation | Child | Syndactyly - genetics | Ethylenediaminetetraacetic acid | Genes | Genomics | Medical genetics | Family | Genomes | Genetic aspects | Nucleotide sequencing | DNA sequencing | Alanine | Disease | Genetic diversity | Family medical history | Proteins | Syndactyly | Software | HOXD13 gene | Deoxyribonucleic acid--DNA | Index Medicus
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6. Full Text Spd1 accumulation causes genome instability independently of ribonucleotide reductase activity but functions to protect the genome when deoxynucleotide pools are elevated
by Fleck, Oliver and Vejrup-Hansen, Rasmus and Watson, Adam and Carr, Antony M and Nielsen, Olaf and Holmberg, Christian
Journal of cell science, ISSN 0021-9533, 11/2013, Volume 126, Issue 21, pp. 4985 - 4994
Checkpoint kinase | Genome instability | Ribonucleotide reductase | Spd1 | Ddb1 | Life Sciences & Biomedicine | Science & Technology | Cell Biology | DNA-Binding Proteins - metabolism | Schizosaccharomyces - genetics | Genomic Instability | Schizosaccharomyces - metabolism | Schizosaccharomyces pombe Proteins - genetics | Genome, Fungal | Deoxyribonucleotides - metabolism | Cell Cycle Proteins - metabolism | Schizosaccharomyces pombe Proteins - metabolism | Cell Cycle Proteins - genetics | Schizosaccharomyces - enzymology | DNA-Binding Proteins - genetics | Index Medicus
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7. Full Text Unravelling pathogenetic mechanisms of epidemic lineages
by Oppegaard, Oddvar
Virulence, ISSN 2150-5594, 10/2017, Volume 8, Issue 7, pp. 1102 - 1104
whole genome sequencing | outbreak | Streptococcus pyogenes | streptodornase | spd1 | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Streptococcal Infections - epidemiology | Epidemics | Disease Outbreaks | Humans | Index Medicus
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8. Full Text Modification of sPD1 with CRT induces potent anti-tumor immune responses in vitro and in vivo
by Wang, Gongze and Li, Zhiying and Tian, Huiqun and Wu, Wei and Liu, Chaoqi
Biomedicine & pharmacotherapy, ISSN 0753-3322, 2015, Volume 76, pp. 57 - 64
Internal Medicine | Medical Education | Tumor immune | Recombinant protein | CRT | Immunotherapy | sPD1 | SPD1 | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Lymphocytes - metabolism | Recombinant Fusion Proteins - immunology | Immunotherapy - methods | Cell Proliferation | Enzyme-Linked Immunosorbent Assay | Melanoma, Experimental - therapy | Survival Rate | Blotting, Western | Programmed Cell Death 1 Receptor - administration & dosage | Animals | Flow Cytometry | Melanoma, Experimental - immunology | Calreticulin - administration & dosage | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Calreticulin - immunology | Programmed Cell Death 1 Receptor - immunology | Recombinant Fusion Proteins - administration & dosage | Immune response | Analysis | Development and progression | T cells | Tumors | Protein binding | Medical colleges | Recombinant proteins | Enzyme-linked immunosorbent assay | Cancer | Index Medicus
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9. Full Text Ddb1 Is Required for the Proteolysis of the Schizosaccharomyces pombe Replication Inhibitor Spd1 during S Phase and after DNA Damage
by Tanya Bondar and Aleksandr Ponomarev and Pradip Raychaudhuri
The Journal of biological chemistry, ISSN 0021-9258, 03/2004, Volume 279, Issue 11, pp. 9937 - 9943
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Schizosaccharomyces pombe Proteins - chemistry | Signal Transduction | Cell Separation | Cell Cycle Proteins - metabolism | Ubiquitin - metabolism | Glutathione Transferase - metabolism | Blotting, Western | Precipitin Tests | Cell Cycle Proteins - chemistry | Schizosaccharomyces - metabolism | DNA - chemistry | Phenotype | Flow Cytometry | Ultraviolet Rays | Time Factors | Ribonucleotide Reductases - antagonists & inhibitors | Gene Deletion | S Phase | Schizosaccharomyces pombe Proteins - metabolism | Protein Binding | DNA Damage | Mutation | Dose-Response Relationship, Radiation | Ddb1 gene | Spd1 gene | signalosome | Cds1 gene | Index Medicus
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10. Full Text The In Vitro Interaction of Streptococcus pyogenes with Human Pharyngeal Cells Induces a Phage-Encoded Extracellular DNase
by Thomas B. Broudy and Vijaykumar Pancholi and Vincent A. Fischetti
Infection and Immunity, ISSN 0019-9567, 06/2002, Volume 70, Issue 6, pp. 2805 - 2811
Infectious Diseases | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains | Biological and medical sciences | Microbiology | Bacteriology | Amino Acid Sequence | Streptococcus Phages - enzymology | Streptococcus Phages - genetics | Streptococcus pyogenes - growth & development | Humans | Bacterial Proteins - genetics | Cells, Cultured | Molecular Sequence Data | Deoxyribonucleases - classification | Streptococcus pyogenes - virology | Sequence Analysis, DNA | Sequence Homology, Amino Acid | Deoxyribonucleases - genetics | Pharynx - cytology | Streptococcus pyogenes - enzymology | Pharynx - microbiology | SpeC protein | Spd1 protein | Index Medicus | Molecular Pathogenesis
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11. Full Text Ribonucleotide reductase activity is regulated by proliferating cell nuclear antigen (PCNA)
by Salguero, Israel and Guarino, Estrella and Shepherd, Marianne and Deegan, Tom and Havens, Courtney G and MacNeill, Stuart A and Walter, Johannes C and Kearsey, Stephen E
Current biology, ISSN 0960-9822, 4/2012, Volume 22, Issue 8, pp. 720 - 726
Cdt2 | ribonucleotide reductase | DNA replication | PCNA | CRL4 | Suc22 | Spd1 | DNA repair | Ddb1 | degron | PIP box | Cul4 | fission yeast | Cdc22
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12. Full Text The Spd1p S phase inhibitor can activate the DNA replication checkpoint pathway in fission yeast
by Borgne, A and Nurse, P
Journal of cell science, ISSN 0021-9533, 12/2000, Volume 113, Issue 23, pp. 4341 - 4350
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phosphorylation | G2 Phase - physiology | Protein-Tyrosine Kinases - metabolism | Schizosaccharomyces pombe Proteins | Cell Cycle Proteins - metabolism | ras Proteins - metabolism | G1 Phase - physiology | Nuclear Proteins | CDC2 Protein Kinase - metabolism | DNA Replication - physiology | Gene Expression - physiology | Cell Cycle Proteins - genetics | S Phase - physiology | Genes, cdc - physiology | Schizosaccharomyces | Spd1p | Fission yeast | Y15 phosphorylation | DNA replication checkpoint | Cdc2p | cds1 protein | rad protein | cdc2 protein | Spd1 protein | chk1 protein | Index Medicus
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13. Full Text Different classes of retrotransposons in coniferous spruce species
by L'Homme, Yvan and Séguin, Armand and Tremblay, Francine M
Genome, ISSN 0831-2796, 12/2000, Volume 43, Issue 6, pp. 1084 - 1089
Copia | Gypsy | PCR | Picea | Spruce | Genetics | Flowers & plants | transposon copia | transposon Spd1 | transposon Ty3 | transposon gypsy | transposon Ty1 | transposon Spc1 | Index Medicus
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