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The New England journal of medicine, ISSN 1533-4406, 2016, Volume 374, Issue 23, pp. 2222 - 2234
Journal Article
LANCET, ISSN 0140-6736, 09/2016, Volume 388, Issue 10048, pp. 963 - 973
Background Few data are available for the efficacy of "triple therapy" with two long-acting bronchodilators and an inhaled corticosteroid in chronic... 
POPULATION | MEDICINE, GENERAL & INTERNAL | LUNG-FUNCTION | EXACERBATIONS | INDIVIDUAL COMPONENTS | TIOTROPIUM | FLUTICASONE PROPIONATE/SALMETEROL | GLYCOPYRRONIUM | COPD | SALMETEROL | SALMETEROL/FLUTICASONE
Journal Article
International Journal of COPD, ISSN 1176-9106, 06/2015, Volume 10, pp. 1015 - 1026
Background: The current Global initiative for chronic Obstructive Lung Disease (GOLD) treatment strategy recommends the use of one or more bronchodilators... 
Clinical trial | agonists | Long-acting muscarinic antagonist | Long-acting β | COPD | clinical trial | COST-EFFECTIVENESS | SAFETY | INHALED CORTICOSTEROIDS | SALMETEROL | FORMOTEROL | OBSTRUCTIVE PULMONARY-DISEASE | PRIMARY-CARE | FLUTICASONE PROPIONATE | RESPIRATORY SYSTEM | DOUBLE-BLIND | TIOTROPIUM | long-acting beta-agonists | long-acting muscarinic antagonist | Bronchodilator Agents - therapeutic use | Indans - adverse effects | Spirometry | Glucocorticoids - administration & dosage | Glucocorticoids - therapeutic use | Bronchodilator Agents - administration & dosage | Humans | Middle Aged | Muscarinic Antagonists - adverse effects | Male | Fluticasone-Salmeterol Drug Combination - therapeutic use | Pulmonary Disease, Chronic Obstructive - physiopathology | Muscarinic Antagonists - therapeutic use | Indans - therapeutic use | Recovery of Function | Fluticasone-Salmeterol Drug Combination - adverse effects | Forced Expiratory Volume | Quinolones - adverse effects | Time Factors | Adrenergic beta-2 Receptor Agonists - adverse effects | Quinolones - therapeutic use | Adrenergic beta-2 Receptor Agonists - therapeutic use | Adult | Female | Surveys and Questionnaires | Indans - administration & dosage | Bronchodilator Agents - adverse effects | Glucocorticoids - adverse effects | Glycopyrrolate - adverse effects | Severity of Illness Index | Pulmonary Disease, Chronic Obstructive - diagnosis | Double-Blind Method | Glycopyrrolate - therapeutic use | Administration, Inhalation | Treatment Outcome | Lung - physiopathology | Glycopyrrolate - analogs & derivatives | Fluticasone-Salmeterol Drug Combination - administration & dosage | Muscarinic Antagonists - administration & dosage | Quinolones - administration & dosage | Glycopyrrolate - administration & dosage | Lung - drug effects | Adrenergic beta-2 Receptor Agonists - administration & dosage | Aged | Nebulizers and Vaporizers | Pulmonary Disease, Chronic Obstructive - drug therapy | Lung diseases, Obstructive | Drug therapy, Combination | Comparative analysis | Drug therapy | Methods | Bronchodilator agents
Journal Article
Journal Article
Journal Article
Medicine (United States), ISSN 0025-7974, 2015, Volume 94, Issue 51, p. e2306
A combination of long-acting anticholinergic agents (LAACs) and long-acting beta(2)-adrenergic receptor agonist (LABA) is effective in improving lung function... 
MORTALITY | MEDICINE, GENERAL & INTERNAL | EFFICACY | INFLAMMATION | EXACERBATIONS | TIOTROPIUM | ANTICHOLINERGICS | FIXED-DOSE COMBINATION | CARDIOVASCULAR SAFETY | GLYCOPYRRONIUM | SALMETEROL | Bronchodilator Agents - administration & dosage | Humans | Middle Aged | Male | Salmeterol Xinafoate - adverse effects | Fluticasone-Salmeterol Drug Combination - adverse effects | Stroke - chemically induced | Tiotropium Bromide - administration & dosage | Adrenergic beta-Agonists - administration & dosage | Aged, 80 and over | Female | Bronchodilator Agents - adverse effects | Cholinergic Antagonists - adverse effects | Adrenergic beta-Agonists - adverse effects | Tiotropium Bromide - adverse effects | Formoterol Fumarate - adverse effects | Administration, Inhalation | Salmeterol Xinafoate - administration & dosage | Cholinergic Antagonists - administration & dosage | Fluticasone-Salmeterol Drug Combination - administration & dosage | Budesonide, Formoterol Fumarate Drug Combination - adverse effects | Taiwan - epidemiology | Aged | Cardiovascular Diseases - chemically induced | Delayed-Action Preparations | Budesonide, Formoterol Fumarate Drug Combination - administration & dosage | Drug Combinations | Cohort Studies | Formoterol Fumarate - administration & dosage | Pulmonary Disease, Chronic Obstructive - drug therapy | Lung diseases, Obstructive | Care and treatment | Usage | Cohort analysis | Research | Risk factors | Bronchodilator agents | Morbidity
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2016, Volume 375, Issue 9, pp. 840 - 849
Journal Article
The lancet respiratory medicine, ISSN 2213-2600, 2013, Volume 1, Issue 3, pp. 210 - 223
Journal Article
Thorax, ISSN 0040-6376, 11/2006, Volume 61, Issue 11, pp. 940 - 944
Background: The homozygous presence of the arginine-16 variant of the β2 adrenoceptor gene ADRB2 reverses the benefits from the regular use of short acting β2... 
polymorphism | ADRB2 | children | salmeterol | Asthma
Journal Article
Respiratory Research, ISSN 1465-9921, 06/2018, Volume 19, Issue 1, pp. 121 - 8
Journal Article
Journal Article
Journal of internal medicine, ISSN 0954-6820, 2013, Volume 273, Issue 6, pp. 584 - 594
Objectives Combinations of inhaled corticosteroids (ICSs) and long‐acting β2‐agonists (LABAs) are recommended for patients with moderate and severe chronic... 
long‐acting β2‐agonists | fluticasone/salmeterol | exacerbations | budesonide/formoterol | inhaled corticosteroids | Exacerbations | Fluticasone/salmeterol | Inhaled corticosteroids | agonists | Budesonide/formoterol | Long-acting β | fluticasone | MANAGEMENT | HEALTHY-SUBJECTS | formoterol | RANDOMIZED CONTROLLED-TRIAL | SALMETEROL/FLUTICASONE | budesonide | PROPIONATE | MEDICINE, GENERAL & INTERNAL | long-acting 2-agonists | salmeterol | BACTERIAL-COLONIZATION | WITHDRAWAL | COPD | Formoterol Fumarate | Glucocorticoids - administration & dosage | Bronchodilator Agents - administration & dosage | Follow-Up Studies | Humans | Middle Aged | Male | Pulmonary Disease, Chronic Obstructive - physiopathology | Secondary Prevention | Ethanolamines - administration & dosage | Dose-Response Relationship, Drug | Time Factors | Albuterol - administration & dosage | Female | Registries | Retrospective Studies | Drug Therapy, Combination | Administration, Inhalation | Albuterol - analogs & derivatives | Treatment Outcome | Androstadienes - administration & dosage | Adrenergic beta-2 Receptor Agonists - administration & dosage | Aged | Budesonide - administration & dosage | Fluticasone-Salmeterol Drug Combination | Respiratory Function Tests | Drug Combinations | Pulmonary Disease, Chronic Obstructive - drug therapy | Prevention | Medicine, Experimental | Medical research | Lung diseases, Obstructive | Corticosteroids
Journal Article