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JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 06/2011, Volume 208, Issue 6, pp. 1279 - 1289
The ability of antigen receptors to engage self-ligands with varying affinity is crucial for lymphocyte development. To further explore this concept, we... 
MEDICINE, RESEARCH & EXPERIMENTAL | NKT CELLS | POSITIVE SELECTION | RECOGNITION | THYMIC SELECTION | NEGATIVE SELECTION | CLONAL DELETION | IMMUNOLOGY | SELF-PEPTIDES | IDENTIFICATION | STAT5 ACTIVATION | ANTIGEN
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 10/2019, Volume 68, Issue 10, pp. 1561 - 1572
Preclinical and clinical studies have suggested that cancer treatment with antitumor antibodies induces a specific adaptive T cell response. A central role in... 
Life Sciences | Non-mutated self-peptides | Human CD20-derived peptides | Follicular lymphoma | CD4+ T cell responses
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 02/2018, Volume 43, Issue 2, pp. 108 - 123
The mechanisms by which a T cell detects antigen using its T cell antigen receptor (TCR) are crucial to our understanding of immunity and the harnessing of T... 
TCR | kinase | phosphatase | signaling | antigen | T cell | Antigen | Signaling | Phosphatase | Kinase | SH2 DOMAIN | ACTIVATION | POSITIVE SELECTION | STRUCTURAL BASIS | CELL ANTIGEN RECEPTOR | LIGAND RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TYROSINE PROTEIN-KINASE | T-CELL | SELF-PEPTIDES | BINDING | Signal Transduction - immunology | Receptors, Antigen, T-Cell - immunology | Animals | Humans
Journal Article
Nature Communications, ISSN 2041-1723, 04/2014, Volume 5, Issue 1, pp. 1 - 14
For decades, the global impact of genomic polymorphisms on the repertoire of peptides presented by major histocompatibility complex (MHC) has remained a matter... 
CANCER-CELLS | COMPLEX | PROTEIN | MINOR HISTOCOMPATIBILITY ANTIGEN | HEMATOPOIETIC-CELL TRANSPLANTATION | MULTIDISCIPLINARY SCIENCES | LEUKEMIA | SELF-PEPTIDES | IDENTIFICATION | T-CELLS | MASS-SPECTROMETRY | Polymorphism, Genetic - genetics | Major Histocompatibility Complex - genetics | Peptides - chemistry | Humans | Alleles
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8
Major histocompatibility complex (MHC) class I molecules (proteins) bind peptides of eight to ten amino acids to present them at the cell surface to cytotoxic... 
FREE-ENERGY CALCULATIONS | TAPASIN DEPENDENCE | COMPLEX | T-CELL RESPONSES | BINDING GROOVE | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | CONFORMATIONAL FLEXIBILITY | ANTIGEN PRESENTATION | SELF-PEPTIDES | PROTEINS
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2014, Volume 192, Issue 7, pp. 2984 - 2993
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 11/2019, Volume 20, Issue 11, pp. 1481 - 1481
Journal Article