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serelaxin (172) 172
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Journal of the American College of Cardiology, ISSN 0735-1097, 01/2013, Volume 61, Issue 2, pp. 196 - 206
Journal Article
EUROPEAN JOURNAL OF HEART FAILURE, ISSN 1388-9842, 07/2017, Volume 19, Issue 7, pp. 961 - 961
Journal Article
Circulation Journal, ISSN 1346-9843, 2015
Background:Serelaxin, a recombinant form of human relaxin-2, is in development for treating acute heart failure (AHF) and a Phase II study in Japanese AHF... 
Serelaxin | Efficacy | Tolerability | Safety | Pharmacokinetics
Journal Article
Revista Española de Cardiología (English Edition), ISSN 1885-5857, 06/2017, Volume 70, Issue 6, pp. 516 - 516
Journal Article
LANCET, ISSN 0140-6736, 05/2013, Volume 381, Issue 9880, pp. 1813 - 1814
Journal Article
JAMA, ISSN 0098-7484, 12/2013, Volume 310, Issue 23, pp. 2533 - 2543
Journal Article
European Journal of Heart Failure, ISSN 1388-9842, 11/2017, Volume 19, Issue 11, pp. 1355 - 1357
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2017, Volume 376, Issue 20, pp. 1956 - 1964
Journal Article
Expert Review of Cardiovascular Therapy, ISSN 1477-9072, 09/2017, Volume 15, Issue 9, pp. 649 - 651
Journal Article
European Journal of Heart Failure, ISSN 1388-9842, 07/2017, Volume 19, Issue 7, pp. 958 - 960
Journal Article
PLOS ONE, ISSN 1932-6203, 05/2018, Volume 13, Issue 5
While the cerebral autoregulation sufficiently protects subcortical brain regions during hypoxia or asphyxia, the cerebral cortex is not as adequately... 
HEMORRHAGIC-SHOCK | CARDIAC-OUTPUT | RESPONSES | ASPHYXIA | NITRIC-OXIDE SYNTHASE | ISOFLURANE | MULTIDISCIPLINARY SCIENCES | CEREBRAL-BLOOD-FLOW | RECEPTORS | AUTOREGULATION | SERELAXIN
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2019, Volume 381, Issue 8, pp. 776 - 777
For most of the past 3000 years, physicians believed that all patients with heart failure had acute heart failure. Heart failure was viewed as an episodic... 
MORTALITY | MEDICINE, GENERAL & INTERNAL | RELAX-AHF | SERELAXIN | Heart failure | Practice | Care and treatment | Physicians | Cardiac patients | Edema | Diuresis | Peptides | Mortality | Beta blockers | Heart diseases | Structure-function relationships
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2019, Volume 512, Issue 4, pp. 799 - 805
The physiological function of endothelial cells plays an important role in maintaining normal cardiovascular function. Endothelial dysfunction induced by AngII... 
Human umbilical vascular endothelial cells | Angiotensin II | H2 relaxin | Mitochondrial fission | APOPTOSIS | FIS1 | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INCREASES | DAMAGE | SERELAXIN | BIOPHYSICS | DYNAMICS | RECEPTORS | Cardiology | Angiotensin | Endothelium
Journal Article
Expert Review of Cardiovascular Therapy, ISSN 1477-9072, 06/2016, Volume 14, Issue 6, pp. 703 - 711
Much progress in the medical therapy of chronic heart failure (HF) has been made in the last decades. The last was the introduction of a new treatment strategy... 
Heart failure | clinical trials | LCZ696 | Pharmacological therapy | serelaxin
Journal Article
Cardiovascular Research, ISSN 0008-6363, 05/2017, Volume 113, Issue 6, pp. 553 - 555
Journal Article
Expert Review of Cardiovascular Therapy, ISSN 1477-9072, 06/2016, Volume 14, Issue 6, pp. 667 - 675
Outcomes for patients with acute heart failure remain suboptimal and treatments principally target improvement of symptoms. To date there has been no therapy... 
heart failure | RELAX-AHF | Relaxin | review | serelaxin
Journal Article
Nobel Medicus, ISSN 1305-2381, 01/2019, Volume 15, Issue 1, pp. 5 - 14
Journal Article
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