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ANTICANCER RESEARCH, ISSN 0250-7005, 11/2019, Volume 39, Issue 11, pp. 6063 - 6066
Background/Aim: Treatment of colorectal cancer (CRC) does not reflect immune interactions between tumours and macro-organisms. Serpin B9 is known as an... 
serpin B9 | prognostic factor | DENDRITIC CELLS | ONCOLOGY | Colorectal cancer | visceral surgery | INHIBITOR | immunosurveillance | CARCINOMA | INFILTRATION | Prognosis | Colorectal carcinoma | Reverse transcription | Gene expression | Metastases | Polymerase chain reaction | Granzyme B | Medical prognosis | Glyceraldehyde-3-phosphate dehydrogenase | Colon | Tumors | Immune system | Cancer
Journal Article
Anticancer Research, ISSN 0250-7005, 07/2018, Volume 38, Issue 7, pp. 4159 - 4167
Background/Aim: Tumour-infiltrating lymphocytes (TILs) and Granzyme B play crucial roles in immune reactions against colorectal carcinoma (CRCa). The inhibitor... 
Lymph node metastasis | Recurrence | CD4 | CD8 | Colorectal carcinoma | Serpin B9 | CD25 | Natural killer cells | CD57 | FoxP3 | CD56 | Tumour-infiltrating lymphocytes | tumour-infiltrating lymphocytes | CLASSIFICATION | CANCER | recurrence | natural killer cells | PROGNOSTIC-FACTOR | ONCOLOGY | T-CELLS | lymph node metastasis | LYMPHOCYTES
Journal Article
International Journal of Cancer, ISSN 0020-7136, 09/2014, Volume 135, Issue 6, pp. 1497 - 1508
Journal Article
Cancer Letters, ISSN 0304-3835, 2013, Volume 341, Issue 2, pp. 178 - 185
Journal Article
Blood Cancer Journal, ISSN 2044-5385, 03/2013, Volume 3, Issue 3, pp. e106 - e106
Tumors develop when infiltrating immune cells contribute growth stimuli, and cancer cells are selected to survive within such a cytotoxic microenvironment. One... 
Immunotoxin | Serine Protease | Treatment Resistance | Targeted Cancer Therapy | Serpin B9 | PI-9 | targeted cancer therapy | APOPTOSIS | CANCER CELLS | PROTEINASE-INHIBITOR-9 | TUMOR-CELLS | serine protease | IN-VITRO | ONCOLOGY | immunotoxin | INHIBITOR | EXPRESSION | STERNBERG CELLS | treatment resistance | Original
Journal Article
Antibodies, ISSN 2073-4468, 01/2013, Volume 2, Issue 4, pp. 19 - 49
  Conventional cancer treatments lack specificity and often cause severe side effects. Targeted therapeutic approaches are therefore preferred, including the... 
serpin B9 | endosomal release | immunotherapy | bio-engineering | immunotoxin | human cytolytic fusion protein | surface-charge
Journal Article
Journal Article
Nephrology, dialysis, transplantation, ISSN 0931-0509, 2012, Volume 27, Issue 7, pp. 2746 - 2754
Serine protease inhibitor B9 (serpinB9) protects against granzyme B-mediated apoptosis and could help to reduce tubular damage under inflammatory conditions... 
PI-9 | viral infection | kidney transplantation | dsRNA receptors | serpins | GRANZYME-B INHIBITOR | DOUBLE-STRANDED-RNA | DENDRITIC CELLS | CYTOMEGALOVIRUS-INFECTION | TRANSPLANT RECIPIENTS | TRANSPLANTATION | PROTEASE INHIBITOR-9 | CYTOTOXIC LYMPHOCYTES | UROLOGY & NEPHROLOGY | IMMUNOCOMPETENT CELLS | EPSTEIN-BARR-VIRUS | PROTEINASE INHIBITOR-9 | Tumor Virus Infections - genetics | Inflammation - pathology | Epithelial Cells - metabolism | Herpesvirus 4, Human - genetics | Tumor Virus Infections - virology | Humans | Polyomavirus Infections - metabolism | Immunoenzyme Techniques | Interferon-Induced Helicase, IFIH1 | Inflammation - metabolism | RNA, Viral - genetics | Inflammation Mediators - metabolism | Epstein-Barr Virus Infections - genetics | RNA, Double-Stranded - metabolism | RNA, Viral - metabolism | Toll-Like Receptor 3 - genetics | DEAD-box RNA Helicases - metabolism | Epithelial Cells - cytology | Kidney Tubules - metabolism | Real-Time Polymerase Chain Reaction | Kidney Diseases - metabolism | Lymphocytes - metabolism | DEAD Box Protein 58 | Poly I-C - pharmacology | Tumor Virus Infections - metabolism | Serpins - genetics | Epstein-Barr Virus Infections - virology | Serpins - metabolism | RNA, Messenger - genetics | Cells, Cultured | BK Virus - genetics | Kidney Transplantation | Lymphocytes - cytology | Reverse Transcriptase Polymerase Chain Reaction | Toll-Like Receptor 3 - metabolism | Blotting, Western | Kidney Tubules - cytology | DEAD-box RNA Helicases - genetics | Biopsy | Polyomavirus Infections - virology | Polyomavirus Infections - genetics | RNA, Double-Stranded - genetics | Kidney Diseases - surgery | Kidney Diseases - virology | Epstein-Barr Virus Infections - metabolism
Journal Article
EMBO reports, ISSN 1469-221X, 10/2011, Volume 12, Issue 10, pp. 1011 - 1017
Journal Article
Journal Article
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 2015, Volume 308, Issue 4, pp. L344 - L357
Pathological fibrosis is driven by a feedback loop in which the fibrotic extracellular matrix is both a cause and consequence of fibroblast activation.... 
Plasminogen activator inhibitor 1 | Extracellular matrix | Mechanotransduction | Hippo | Idiopathic pulmonary fibrosis | LUNG | DOMAIN | PHYSIOLOGY | mechanotransduction | HIPPO PATHWAY | idiopathic pulmonary fibrosis | TRANSCRIPTIONAL COACTIVATOR | plasminogen activator inhibitor 1 | GROWTH-FACTOR-BETA | MECHANICAL MEMORY | MATRIX STIFFNESS | INHIBITION | RESPIRATORY SYSTEM | DIFFERENTIATION | IDIOPATHIC PULMONARY-FIBROSIS | extracellular matrix | NIH 3T3 Cells | Humans | Male | Intracellular Signaling Peptides and Proteins - metabolism | Pulmonary Fibrosis - genetics | Phosphoproteins - metabolism | Serpin E2 - biosynthesis | Gene Knockdown Techniques | Female | Lung - metabolism | Pulmonary Fibrosis - metabolism | Plasminogen Activator Inhibitor 1 - genetics | Intracellular Signaling Peptides and Proteins - genetics | Mechanotransduction, Cellular - genetics | Fibroblasts - metabolism | Lung - pathology | Pulmonary Fibrosis - pathology | Phosphoproteins - genetics | Fibroblasts - pathology | Plasminogen Activator Inhibitor 1 - biosynthesis | Serpin E2 - genetics | Animals | Transforming Growth Factor beta - genetics | Adaptor Proteins, Signal Transducing - genetics | Mice, Inbred NOD | Mice | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Transforming Growth Factor beta - metabolism | Transcriptional coactivators | Fibroblasts | Genetic aspects | Pulmonary fibrosis | Health aspects | Oncogenes | Call for Papers
Journal Article