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index medicus (288) 288
serum (209) 209
animals (206) 206
protein-serine-threonine kinases - metabolism (161) 161
humans (153) 153
immediate-early proteins - metabolism (120) 120
protein-serine-threonine kinases - genetics (120) 120
physiology (99) 99
mice (96) 96
phosphorylation (90) 90
immediate-early proteins - genetics (88) 88
cell biology (81) 81
protein-kinase (78) 78
activation (70) 70
male (70) 70
sgk1 (68) 68
expression (63) 63
female (62) 62
biochemistry & molecular biology (61) 61
kinases (56) 56
rats (51) 51
cell line (48) 48
signal transduction (46) 46
apoptosis (44) 44
aldosterone (43) 43
gene expression (42) 42
original paper (41) 41
epithelial na+ channel (40) 40
urogenital system (40) 40
corticosteroids (39) 39
cells, cultured (38) 38
immediate-early proteins (37) 37
urology & nephrology (36) 36
proteins (35) 35
sodium - metabolism (35) 35
cells (33) 33
protein-serine-threonine kinases - physiology (32) 32
rodents (32) 32
glucocorticoids (31) 31
insulin (30) 30
phosphatidylinositol 3-kinases - metabolism (30) 30
nedd4 ubiquitin protein ligases (27) 27
nuclear proteins (27) 27
epithelial sodium channels (25) 25
epithelial sodium channels - metabolism (25) 25
transport (25) 25
xenopus laevis (25) 25
article (24) 24
protein kinases (24) 24
research (24) 24
sodium (24) 24
biochemistry (23) 23
mutation (23) 23
neurosciences (23) 23
pharmacology & pharmacy (23) 23
research article (23) 23
ubiquitin ligase nedd4-2 (23) 23
ubiquitin-protein ligases - metabolism (23) 23
dexamethasone - pharmacology (22) 22
glucocorticoid-inducible kinase (22) 22
mice, knockout (22) 22
signal transduction - drug effects (22) 22
transfection (22) 22
akt (21) 21
gene (21) 21
gene-expression (21) 21
proto-oncogene proteins c-akt - metabolism (21) 21
sodium channels - metabolism (21) 21
biophysics (20) 20
immediate-early proteins - physiology (20) 20
rats, sprague-dawley (20) 20
rna, messenger - metabolism (20) 20
sgk (20) 20
cancer (19) 19
cell line, tumor (19) 19
enac (19) 19
kidney (19) 19
kinase (19) 19
oncology (19) 19
physiological aspects (19) 19
protein-serine-threonine kinases - antagonists & inhibitors (19) 19
threonine protein-kinase (19) 19
up-regulation (19) 19
aldosterone - pharmacology (18) 18
inflammation (18) 18
inhibition (18) 18
molecular sequence data (18) 18
channel (17) 17
collecting duct (17) 17
epithelial sodium channel (17) 17
health aspects (17) 17
hypertension (17) 17
immediate-early proteins - antagonists & inhibitors (17) 17
nedd4-2 (17) 17
phosphoinositide 3-kinase (17) 17
reverse transcriptase polymerase chain reaction (17) 17
transcription (17) 17
down-regulation (16) 16
endocrinology & metabolism (16) 16
epithelial cells - metabolism (16) 16
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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2015, Volume 35, Issue 3, pp. 547 - 557
OBJECTIVE—Atherosclerosis, an inflammatory disease of arterial vessel walls, requires migration and matrix metalloproteinase (MMP)-9–dependent invasion of... 
Inflammation | Migration and invasion protein | Atherosclerosis | Serum-glucocorticoid regulated kinase | atherosclerosis | migration and invasion protein | APOE-NULL MICE | ATHEROSCLEROTIC PLAQUES | INCREASED EXPRESSION | PATHOGENIC T(H)17 CELLS | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | NEOINTIMA FORMATION | MATRIX METALLOPROTEINASE-3 | inflammation | MUSCLE-CELL MIGRATION | PERIPHERAL VASCULAR DISEASE | serum-glucocorticoid regulated kinase | HEMATOLOGY | NF-KAPPA-B | E-DEFICIENT MICE | Inflammation - pathology | Protein-Serine-Threonine Kinases - deficiency | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Humans | Male | Immediate-Early Proteins - metabolism | Matrix Metalloproteinase 9 - metabolism | Carotid Artery Diseases - pathology | Matrix Metalloproteinase 9 - genetics | Peritonitis - genetics | Carotid Arteries - enzymology | Immediate-Early Proteins - deficiency | Transcription, Genetic | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Atherosclerosis - pathology | Macrophages - pathology | NF-kappa B p50 Subunit - metabolism | Signal Transduction | Matrix Metalloproteinase 2 - metabolism | Plaque, Atherosclerotic | Macrophages - enzymology | Mice, Knockout | Aorta - pathology | Aortic Diseases - genetics | Peritonitis - enzymology | Immediate-Early Proteins - genetics | Carotid Artery Diseases - enzymology | Carotid Artery Diseases - genetics | Mutation | Inflammation - enzymology | Vascular Remodeling | I-kappa B Proteins - metabolism | Atherosclerosis - enzymology | Transfection | I-kappa B Kinase - metabolism | Thioglycolates | Aortic Diseases - enzymology | Active Transport, Cell Nucleus | Aorta - enzymology | Aortic Diseases - pathology | Cell Line | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Peritonitis - chemically induced | Chemotaxis | Gene Expression Regulation, Enzymologic | Animals | Apolipoproteins E - genetics | Inflammation - genetics | Carotid Arteries - pathology | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2013, Volume 288, Issue 52, pp. 36841 - 36854
Journal Article
Diabetes, ISSN 0012-1797, 07/2006, Volume 55, Issue 7, pp. 2059 - 2066
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2012, Volume 166, Issue 4, pp. 1272 - 1289
BACKGROUND AND PURPOSE Glucocorticoids appear to control Na + absorption in pulmonary epithelial cells via a mechanism dependent upon serum and... 
epithelial Na | H441 cells | serum and glucocorticoid‐regulated kinase 1 | pulmonary Na | TORC2 | absorption | channel | 3‐phosphatidylinositol phosphate kinase | 3-phosphatidylinositol phosphate kinase | serum and glucocorticoid-regulated kinase 1 | SERINE PROTEASES | ALPHA-SUBUNIT | PROTEIN-KINASE | SODIUM-CHANNEL | PKB-ALPHA | epithelial Na plus channel | SIGNAL-TRANSDUCTION | PHARMACOLOGY & PHARMACY | CYSTIC-FIBROSIS | GAMMA-SUBUNIT | SGK1 | MTOR COMPLEX | pulmonary Na plus absorption | Respiratory Mucosa - drug effects | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Humans | Epithelial Sodium Channels - metabolism | Protein Subunits - metabolism | Immediate-Early Proteins - metabolism | Dexamethasone - pharmacology | Protein Processing, Post-Translational - drug effects | Time Factors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Phosphorylation - drug effects | Phosphatidylinositol 3-Kinase - metabolism | Protein-Serine-Threonine Kinases - metabolism | Membrane Potentials - drug effects | Cell Line | Enzyme Inhibitors - pharmacology | Respiratory Mucosa - enzymology | Transcription Factors - antagonists & inhibitors | Enzyme Activation - drug effects | Transcription Factors - metabolism | Up-Regulation - drug effects | Signal Transduction - drug effects | Glucocorticoids - pharmacology | Respiratory Mucosa - metabolism | Immediate-Early Proteins - antagonists & inhibitors | Sodium | Kinases | Index Medicus | Research Papers | pulmonary Na+ absorption | epithelial Na+ channel
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 05/2008, Volume 105, Issue 3, pp. 820 - 832
Journal Article
International Journal of Andrology, ISSN 0105-6263, 08/2011, Volume 34, Issue 4pt1, pp. 379 - 389
Journal Article
Journal Article
American journal of physiology. Renal physiology, ISSN 1931-857X, 10/2018, Volume 315, Issue 4, pp. F1058 - F1066
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 10/2006, Volume 399, pp. 69 - 76
The serine/threonine protein kinase Sgk1 (serum- and glucocorticoid-inducible kinase 1) is characterized by a short half-life and has been implicated in the... 
localization | OUTER-MEMBRANE | CELLS | ISOFORMS | mitochondria | outer mitochondrial membrane | topology | EPITHELIAL NA+ CHANNEL | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUBCELLULAR-LOCALIZATION | SIGNALS | half-life | serum- and glucocorticoid-inducible kinase 1 (Sgk1) | FAMILY | UBIQUITIN LIGASE NEDD4-2 | THREONINE PROTEIN-KINASE | EXPRESSION
Journal Article
Journal of Cancer, ISSN 1837-9664, 2017, Volume 8, Issue 12, pp. 2256 - 2262
Colorectal cancer (CRC) is one of the most leading causes of cancer-related death worldwide. The serum and glucocorticoid inducible kinase SGK1 is highly... 
Cell proliferation | Serum and glucocorticoid inducible kinase 1 | Inhibitor | Cell migration | Colonic tumor growth | Colorectal cancer | APOPTOSIS | ACTIVATION | PROTEIN-KINASE | SERUM | EMD638683 | ONCOLOGY | GENES | TUMOR-GROWTH
Journal Article
Biochemical Journal, ISSN 0264-6021, 10/2006, Volume 399, Issue 1, pp. 69 - 76
The serine/threonine protein kinase Sgk1 (serum- and glucocorticoid-inducible kinase 1) is characterized by a short half-life and has been implicated in the... 
Mitochondria | Serum- and glucocorticoid-inducible kinase 1 (Sgk1) | Half-life | Topology | Localization | Outer mitochondrial membrane | Amino Acid Sequence | Cell Line | Mitochondria - enzymology | Humans | Kidney - cytology | Mitochondria - metabolism | Mice, Knockout | Mitochondrial Membranes - metabolism | Protein Transport | Immediate-Early Proteins - metabolism | Animals | Immediate-Early Proteins - chemistry | Mice | Protein Processing, Post-Translational | Protein-Serine-Threonine Kinases - chemistry | Protein-Serine-Threonine Kinases - metabolism | Index Medicus | localization | OMM, outer mitochondrial membrane | HEK-293 cells, human embryonic kidney cells | Hsp60, heat-shock protein 60 | GFP, green fluorescent protein | Grp78, 78 kDa glucose-regulated protein | mitochondria | outer mitochondrial membrane | topology | Sgk1, serum- and glucocorticoid-inducible kinase 1 | DAPI, 4′,6-diamidino-2-phenylindole | half-life | NP40, Nonidet P40 | serum- and glucocorticoid-inducible kinase 1 (Sgk1) | ENaC, epithelial sodium channel | Nedd4-2, neural precursor cell expressed, developmentally down-regulated 4-2 | FOXO3a, forkhead box O3a | BiP, immunoglobulin heavy-chain binding protein | DMEM, Dulbecco's modified Eagle's medium | DIABLO, direct IAP (inhibitor of apoptosis protein) binding protein with low pI | Smac, second mitochondria-derived activator of caspase | GAPDH, glyceraldehyde-3-phosphate dehydrogenase
Journal Article